Expression of macrophage inflammatory protein-1α and monocyte chemoattractant protein-1 in glioma-infiltrating microglia: Involvement of ATP and P2X7 receptor

Journal of Neuroscience Research

Volumn 89, Issue 2, 2011, Pages 199-211

  Fang, Kuan Min ^a   Wang, Ying Lan ^a   Huang, Ming Chao ^b   Sun, Synthia H ^c   Cheng, Henrich ^b,c   Tzeng, Shun Fen ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

ATP; Chemokine; Glioma; Microglia; Purinergic receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRILLIANT BLUE; CALCIUM ION; EGTAZIC ACID; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GLIOMA; GLIOMA CELL; IN VITRO STUDY; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE, TUMOR; CHEMOKINE CCL2; CHEMOKINE CCL3; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLIOMA; IMMUNOHISTOCHEMISTRY; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2X;

EID: 78650197453     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22538     Document Type: Article

References (51)

1. Aloisi F. 2001. Immune function of microglia. Glia 36: 165-179.
2. Asensio VC, Campbell IL. 2001. Chemokines and viral diseases of the central nervous system. Adv Virus Res 56: 127-173.
3. Babcock AA, Kuziel WA, Rivest S, Owens T. 2003. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci 23: 7922-7930.
4. Badie B, Schartner J. 2001. Role of microglia in glioma biology. Microsc Res Techniq 54: 106-113.
5. Baggiolini M. 1998. Chemokines and leukocyte traffic. Nature 392: 565-568.
6. Bajetto A, Bonavia R, Barbero S, Schettini G. 2002. Characterization of chemokines and their receptors in the central nervous system: physiopathological implications. J Neurochem 82: 1311-1329.
7. Barron KD. 1995. The microglial cell. A historical review. J Neurol Sci 134(Suppl): 57-68.
8. Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, Kang J, Naus CC, Nedergaard M. 1998. Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci U S A 95: 15735-15740.
9. Cowell RM, Xu H, Galasso JM, Silverstein FS. 2002. Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brain. Stroke 33: 795-801.
10. Cuadros MA, Navascues J. 1998. The origin and differentiation of microglial cells during development. Prog Neurobiol 56: 173-189.
11. Desbaillets I, Tada M, de Tribolet N, Diserens AC, Hamou MF, Van Meir EG. 1994. Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro. Int J Cancer 58: 240-247.
12. Dickson DW, Lee SC, Mattiace LA, Yen SH, Brosnan C. 1993. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7: 75-83.
13. Fang KM, Yang CS, Sun SH, Tzeng SF. 2009. Microglial phagocytosis attenuated by short-term exposure to exogenous ATP through P2X receptor action. J Neurochem 111: 1225-1237.
14. Fields RD, Burnstock G. 2006. Purinergic signalling in neuron-glia interactions. Nat Rev Neurosci 7: 423-436.
15. Graeber MB, Scheithauer BW, Kreutzberg GW. 2002. Microglia in brain tumors. Glia 40: 252-259.
16. Harden TK, Lazarowski ER. 1999. Release of ATP and UTP from astrocytoma cells. Prog Brain Res 120: 135-143.
17. Haynes SE, Hollopeter G, Yang G, Kurpius D, Dailey ME, Gan WB, Julius D. 2006. The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat Neurosci 9: 1512-1519.
18. Hide I, Tanaka M, Inoue A, Nakajima K, Kohsaka S, Inoue K, Nakata Y. 2000. Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem 75: 965-972.
19. Hockel M, Vaupel P. 2001. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. JNCI 93: 266-276.
20. Inoue K. 2002. Microglial activation by purines and pyrimidines. Glia 40: 156-163.
21. Inoue K, Koizumi S, Tsuda M. 2007. The role of nucleotides in the neuron-glia communication responsible for the brain functions. J Neurochem 102: 1447-1458.
22. Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S. 1998. Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Res Mol Brain Res 57: 1-9.
23. Jantaratnotai N, Choi HB, McLarnon JG. 2009. ATP stimulates chemokine production via a store-operated calcium entry pathway in C6 glioma cells. BMC cancer 9: 442.
24. 7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J Neurochem 108: 115-125.
25. Katayama T, Ito M, Kaneko S, Satoh M, Uehara T, Minami M. 2009. Reciprocal regulation of ATPgammaS-induced monocyte chemoattractant protein-1 production by ERK and p38 MAP kinases in rat corticostriatal slice cultures. J Neurosci Res 87: 1573-1581.
26. Kreutzberg GW. 1996. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19: 312-318.
27. Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. 2006. Malignant glioma progression and nitric oxide. Neurochem Int 49: 764-768.
28. Leung SY, Wong MP, Chung LP, Chan AS, Yuen ST. 1997. Monocyte chemoattractant protein-1 expression and macrophage infiltration in gliomas. Acta Neuropathol 93: 518-527.
29. Liu B, Hong JS. 2003. Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 304: 1-7.
30. McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85: 890-902.
31. McManus CM, Brosnan CF, Berman JW. 1998. Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia. J Immunol 160: 1449-1455.
32. Melchers F, Rolink AG, Schaniel C. 1999. The role of chemokines in regulating cell migration during humoral immune responses. Cell 99: 351-354.
33. Mishima K, Higashiyama S, Asai A, Yamaoka K, Nagashima Y, Taniguchi N, Kitanaka C, Kirino T, Kuchino Y. 1998. Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas. Acta Neuropathol 96: 322-328.
34. Morimura T, Neuchrist C, Kitz K, Budka H, Scheiner O, Kraft D, Lassmann H. 1990. Monocyte subpopulations in human gliomas: expression of Fc and complement receptors and correlation with tumor proliferation. Acta Neuropathol 80: 287-294.
35. Morioka T, Baba T, Black KL, Streit WJ. 1992. Response of microglial cells to experimental rat glioma. Glia 6: 75-79.
36. Morrone FB, Horn AP, Stella J, Spiller F, Sarkis JJ, Salbego CG, Lenz G, Battastini AM. 2005. Increased resistance of glioma cell lines to extracellular ATP cytotoxicity. J Neurooncol 71: 135-140.
37. Morrone FB, Oliveira DL, Gamermann P, Stella J, Wofchuk S, Wink MR, Meurer L, Edelweiss MI, Lenz G, Battastini AM. 2006. In vivo glioblastoma growth is reduced by apyrase activity in a rat glioma model. BMC Cancer 6: 226.
38. North RA, Barnard EA. 1997. Nucleotide receptors. Curr Opin Neurobiol 7: 346-357.
39. Ohsawa K, Irino Y, Nakamura Y, Akazawa C, Inoue K, Kohsaka S. 2007. Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis. Glia 55: 604-616.
40. Platten M, Kretz A, Naumann U, Aulwurm S, Egashira K, Isenmann S, Weller M. 2003. Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann Neurol 54: 388-392.
41. Ralevic V, Burnstock G. 1998. Receptors for purines and pyrimidines. Pharmacol Rev 50: 413-492.
42. Robins HI, Peterson CG, Mehta MP. 2003. Combined modality treatment for central nervous system malignancies. Semin Oncol 30(Suppl 9): 11-22.
43. Roggendorf W, Strupp S, Paulus W. 1996. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol 92: 288-293.
44. Sanz JM, Di Virgilio F. 2000. Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells. J Immunol 164: 4893-4898.
45. Streit WJ. 1994. Cellular immune response in brain tumors. Neuropathol Appl Neurobiol 20: 205-206.
46. Streit WJ. 2002. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 40: 133-139.
47. Watters JJ, Schartner JM, Badie B. 2005. Microglia function in brain tumors. J Neurosci Res 81: 447-455.
48. Wierzba-Bobrowicz T, Kuchna I, Matyja E. 1994. Reaction of microglial cells in human astrocytomas (preliminary report). Fol Neuropathol 32: 251-252.
49. Wink MR, Lenz G, Braganhol E, Tamajusuku AS, Schwartsmann G, Sarkis JJ, Battastini AM. 2003. Altered extracellular ATP, ADP and AMP catabolism in glioma cell lines. Cancer Lett 198: 211-218.
50. Yang I, Han SJ, Kaur G, Crane C, Parsa AT. 2010. The role of microglia in central nervous system immunity and glioma immunology. J Clin Neurosci 17: 6-10.
51. Zlotnik A, Yoshie O. 2000. Chemokines: a new classification system and their role in immunity. Immunity 12: 121-127.