-
2
-
-
0024415865
-
Early detection of prostate cancer
-
Scardino PT. Early detection of prostate cancer. Urol Clin North Am 1989;16:635-55.
-
(1989)
Urol Clin North Am
, vol.16
, pp. 635-655
-
-
Scardino, P.T.1
-
4
-
-
84891835267
-
Castration-resistant prostate cancer: From new pathophysiology to new treatment
-
Sridhar SS, Freedland SJ, Gleave ME, Higano C, Mulders P, Parker C, et al. Castration-resistant prostate cancer: from new pathophysiology to new treatment. Eur Urol 2014;65: 289-99.
-
(2014)
Eur Urol
, vol.65
, pp. 289-299
-
-
Sridhar, S.S.1
Freedland, S.J.2
Gleave, M.E.3
Higano, C.4
Mulders, P.5
Parker, C.6
-
6
-
-
64349120177
-
Targeting TGF-beta in prostate cancer: Therapeutic possibilities during tumor progression
-
Jones E, Pu H, Kyprianou N. Targeting TGF-beta in prostate cancer: Therapeutic possibilities during tumor progression. Expert Opin Ther Targets 2009;13:227-34.
-
(2009)
Expert Opin Ther Targets
, vol.13
, pp. 227-234
-
-
Jones, E.1
Pu, H.2
Kyprianou, N.3
-
7
-
-
84894059406
-
Molecular alterations and emerging targets in castration resistant prostate cancer
-
Lorente D, De Bono JS. Molecular alterations and emerging targets in castration resistant prostate cancer. Eur J Cancer 2014;50:753-64.
-
(2014)
Eur J Cancer
, vol.50
, pp. 753-764
-
-
Lorente, D.1
De Bono, J.S.2
-
8
-
-
0842346190
-
Transforming growth factorbeta- related proteins: An ancestral and widespread superfamily of cytokines in metazoans
-
Herpin A, Lelong C, Favrel P. Transforming growth factorbeta- related proteins: An ancestral and widespread superfamily of cytokines in metazoans. Dev Comp Immunol 2004; 28:461-85.
-
(2004)
Dev Comp Immunol
, vol.28
, pp. 461-485
-
-
Herpin, A.1
Lelong, C.2
Favrel, P.3
-
9
-
-
84866742560
-
TGFbeta signalling in context
-
Massague J. TGFbeta signalling in context. Nat Rev Mol Cell Biol 2012;13:616-30.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 616-630
-
-
Massague, J.1
-
10
-
-
0027724228
-
Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease
-
Kulkarni AB, Karlsson S. Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease. Am J Pathol 1993;143:3-9.
-
(1993)
Am J Pathol
, vol.143
, pp. 3-9
-
-
Kulkarni, A.B.1
Karlsson, S.2
-
11
-
-
0028972869
-
Transforming growth factor-beta 3 is required for secondary palate fusion
-
Proetzel G, Pawlowski SA, Wiles MV, Yin M, Boivin GP, Howles PN, et al. Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet 1995;11:409-14.
-
(1995)
Nat Genet
, vol.11
, pp. 409-414
-
-
Proetzel, G.1
Pawlowski, S.A.2
Wiles, M.V.3
Yin, M.4
Boivin, G.P.5
Howles, P.N.6
-
12
-
-
0030609894
-
TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
-
Sanford LP, Ormsby I, Gittenberger-de Groot AC, Sariola H, Friedman R, Boivin GP, et al. TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes. Development 1997;124:2659-70.
-
(1997)
Development
, vol.124
, pp. 2659-2670
-
-
Sanford, L.P.1
Ormsby, I.2
Gittenberger-De, G.A.C.3
Sariola, H.4
Friedman, R.5
Boivin, G.P.6
-
14
-
-
0031990782
-
Overexpression of transforming growth factor (TGF) beta1 type II receptor restores TGF-beta1 sensitivity and signaling in human prostate cancer cells
-
Guo Y, Kyprianou N. Overexpression of transforming growth factor (TGF) beta1 type II receptor restores TGF-beta1 sensitivity and signaling in human prostate cancer cells. Cell Growth Differ 1998;9:185-93.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 185-193
-
-
Guo, Y.1
Kyprianou, N.2
-
15
-
-
0034644472
-
TGFbeta signaling in growth control, cancer, and heritable disorders
-
Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 2000;103: 295-309.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
16
-
-
0036144377
-
TGFbeta induces apoptosis through smad-mediated expression of DAP-kinase
-
Jang CW, Chen CH, Chen CC, Chen JY, Su YH, Chen RH. TGFbeta induces apoptosis through smad-mediated expression of DAP-kinase. Nat Cell Biol 2002;4:51-8.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 51-58
-
-
Jang, C.W.1
Chen, C.H.2
Chen, C.C.3
Chen, J.Y.4
Su, Y.H.5
Chen, R.H.6
-
17
-
-
70450221920
-
4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation
-
Azar R, Alard A, Susini C, Bousquet C, Pyronnet S. 4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation. EMBO J 2009;28:3514-22.
-
(2009)
EMBO J
, vol.28
, pp. 3514-3522
-
-
Azar, R.1
Alard, A.2
Susini, C.3
Bousquet, C.4
Pyronnet, S.5
-
18
-
-
79951472098
-
Identification of an mRNP complex regulating tumorigenesis at the translational elongation step
-
Hussey GS, Chaudhury A, Dawson AE, Lindner DJ, Knudsen CR, Wilce MC, et al. Identification of an mRNP complex regulating tumorigenesis at the translational elongation step. Mol Cell 2011;41:419-31.
-
(2011)
Mol Cell
, vol.41
, pp. 419-431
-
-
Hussey, G.S.1
Chaudhury, A.2
Dawson, A.E.3
Lindner, D.J.4
Knudsen, C.R.5
Wilce, M.C.6
-
19
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
-
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol Cell 2000;6:1365-75.
-
(2000)
Mol Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
-
20
-
-
27244445059
-
Transforming growth factor beta and prostate cancer
-
Zhu B, Kyprianou N. Transforming growth factor beta and prostate cancer. Cancer Treat Res 2005;126:157-73.
-
(2005)
Cancer Treat Res
, vol.126
, pp. 157-173
-
-
Zhu, B.1
Kyprianou, N.2
-
21
-
-
84899538936
-
Cofilin drives cell-invasive and metastatic responses to TGFbeta in prostate cancer
-
Collazo J, Zhu B, Larkin S, Martin SK, Pu H, Horbinski C, et al. Cofilin drives cell-invasive and metastatic responses to TGFbeta in prostate cancer. Cancer Res 2014;74:2362-73.
-
(2014)
Cancer Res
, vol.74
, pp. 2362-2373
-
-
Collazo, J.1
Zhu, B.2
Larkin, S.3
Martin, S.K.4
Pu, H.5
Horbinski, C.6
-
22
-
-
33749017960
-
Prohibitin and cofilin are intracellular effectors of transforming growth factor beta signaling in human prostate cancer cells
-
Zhu B, Fukada K, Zhu H, Kyprianou N. Prohibitin and cofilin are intracellular effectors of transforming growth factor beta signaling in human prostate cancer cells. Cancer Res 2006; 66:8640-7.
-
(2006)
Cancer Res
, vol.66
, pp. 8640-8647
-
-
Zhu, B.1
Fukada, K.2
Zhu, H.3
Kyprianou, N.4
-
23
-
-
34748819999
-
TGF-beta receptor 2 downregulation in tumourassociated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: A retrospective study
-
Bacman D, Merkel S, Croner R, Papadopoulos T, Brueckl W, Dimmler A. TGF-beta receptor 2 downregulation in tumourassociated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: A retrospective study. BMC Cancer 2007;7:156.
-
(2007)
BMC Cancer
, vol.7
, pp. 156
-
-
Bacman, D.1
Merkel, S.2
Croner, R.3
Papadopoulos, T.4
Brueckl, W.5
Dimmler, A.6
-
24
-
-
33845979811
-
The type III TGF-beta receptor suppresses breast cancer progression
-
Dong M, How T, Kirkbride KC, Gordon KJ, Lee JD, Hempel N, et al. The type III TGF-beta receptor suppresses breast cancer progression. J Clin Invest 2007;117:206-17.
-
(2007)
J Clin Invest
, vol.117
, pp. 206-217
-
-
Dong, M.1
How, T.2
Kirkbride, K.C.3
Gordon, K.J.4
Lee, J.D.5
Hempel, N.6
-
25
-
-
0030979568
-
Down-regulation of protein and mRNA expression for transforming growth factor-beta (TGF-beta1) type I and type II receptors in human prostate cancer
-
Guo Y, Jacobs SC, Kyprianou N. Down-regulation of protein and mRNA expression for transforming growth factor-beta (TGF-beta1) type I and type II receptors in human prostate cancer. Int J Cancer 1997;71:573-9.
-
(1997)
Int J Cancer
, vol.71
, pp. 573-579
-
-
Guo, Y.1
Jacobs, S.C.2
Kyprianou, N.3
-
26
-
-
0033559189
-
Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1- mediated apoptosis
-
Guo Y, Kyprianou N. Restoration of transforming growth factor beta signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1- mediated apoptosis. Cancer Res 1999;59:1366-71.
-
(1999)
Cancer Res
, vol.59
, pp. 1366-1371
-
-
Guo, Y.1
Kyprianou, N.2
-
27
-
-
70349742484
-
Dysfunctional transforming growth factor-beta receptor II accelerates prostate tumorigenesis in the TRAMP mouse model
-
Pu H, Collazo J, Jones E, Gayheart D, Sakamoto S, Vogt A, et al. Dysfunctional transforming growth factor-beta receptor II accelerates prostate tumorigenesis in the TRAMP mouse model. Cancer Res 2009;69:7366-74.
-
(2009)
Cancer Res
, vol.69
, pp. 7366-7374
-
-
Pu, H.1
Collazo, J.2
Jones, E.3
Gayheart, D.4
Sakamoto, S.5
Vogt, A.6
-
28
-
-
84881245194
-
Improvement of a predictive model of castration-resistant prostate cancer: Functional genetic variants in TGFbeta1 signaling pathway modulation
-
Teixeira AL, Gomes M, Nogueira A, Azevedo AS, Assis J, Dias F, et al. Improvement of a predictive model of castration-resistant prostate cancer: functional genetic variants in TGFbeta1 signaling pathway modulation. PLoS One 2013;8:e72419.
-
(2013)
PLoS One
, vol.8
, pp. e72419
-
-
Teixeira, A.L.1
Gomes, M.2
Nogueira, A.3
Azevedo, A.S.4
Assis, J.5
Dias, F.6
-
29
-
-
77953026276
-
Roles for the type III TGF-beta receptor in human cancer
-
Gatza CE, Oh SY, Blobe GC. Roles for the type III TGF-beta receptor in human cancer. Cell Signal 2010;22:1163-74.
-
(2010)
Cell Signal
, vol.22
, pp. 1163-1174
-
-
Gatza, C.E.1
Oh, S.Y.2
Blobe, G.C.3
-
31
-
-
33847069683
-
The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer
-
Turley RS, Finger EC, Hempel N, How T, Fields TA, Blobe GC. The type III transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer. Cancer Res 2007;67:1090-8.
-
(2007)
Cancer Res
, vol.67
, pp. 1090-1098
-
-
Turley, R.S.1
Finger, E.C.2
Hempel, N.3
How, T.4
Fields, T.A.5
Blobe, G.C.6
-
32
-
-
14944363173
-
Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer
-
Bandyopadhyay A, Wang L, López-Casillas F, Mendoza V, Yeh IT, Sun L. Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer. Prostate 2005;63:81-90.
-
(2005)
Prostate
, vol.63
, pp. 81-90
-
-
Bandyopadhyay, A.1
Wang, L.2
López-Casillas, F.3
Mendoza, V.4
Yeh, I.T.5
Sun, L.6
-
33
-
-
78649903609
-
Overexpression of transforming growth factor beta1 in malignant prostate cells is partly caused by a runaway of TGFbeta1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-beta type I receptor
-
e8e1519.e13
-
Yu N, Kozlowski JM, Park II, Chen L, Zhang Q, Xu D, et al. Overexpression of transforming growth factor beta1 in malignant prostate cells is partly caused by a runaway of TGFbeta1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-beta type I receptor. Urology 2010;76:1519.e8e1519.e13.
-
(2010)
Urology
, vol.76
, pp. 1519
-
-
Yu, N.1
Kozlowski, J.M.2
Park, I.I.3
Chen, L.4
Zhang, Q.5
Xu, D.6
-
34
-
-
80053601066
-
TGF-beta regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence
-
Zhang Q, Chen L, Helfand BT, Jang TL, Sharma V, Kozlowski J, et al. TGF-beta regulates DNA methyltransferase expression in prostate cancer, correlates with aggressive capabilities, and predicts disease recurrence. PLoS One 2011;6:e25168.
-
(2011)
PLOS ONE
, vol.6
, pp. e25168
-
-
Zhang, Q.1
Chen, L.2
Helfand, B.T.3
Jang, T.L.4
Sharma, V.5
Kozlowski, J.6
-
35
-
-
79958698402
-
TRAF6 ubiquitinates TGFbeta type I receptor to promote its cleavage and nuclear translocation in cancer
-
Mu Y, Sundar R, Thakur N, Ekman M, Gudey SK, Yakymovych M, et al. TRAF6 ubiquitinates TGFbeta type I receptor to promote its cleavage and nuclear translocation in cancer. Nat Commun 2011;2:330.
-
(2011)
Nat Commun
, vol.2
, pp. 330
-
-
Mu, Y.1
Sundar, R.2
Thakur, N.3
Ekman, M.4
Gudey, S.K.5
Yakymovych, M.6
-
36
-
-
33646386905
-
The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors
-
Wang W, Mouneimne G, Sidani M, Wyckoff J, Chen X, Makris A, et al. The activity status of cofilin is directly related to invasion, intravasation, and metastasis of mammary tumors. J Cell Biol 2006;173:395-404.
-
(2006)
J Cell Biol
, vol.173
, pp. 395-404
-
-
Wang, W.1
Mouneimne, G.2
Sidani, M.3
Wyckoff, J.4
Chen, X.5
Makris, A.6
-
37
-
-
58249122148
-
Androgen receptor and growth factor signaling cross-talk in prostate cancer cells
-
Zhu ML, Kyprianou N. Androgen receptor and growth factor signaling cross-talk in prostate cancer cells. Endocr Relat Cancer 2008;15:841-9.
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 841-849
-
-
Zhu, M.L.1
Kyprianou, N.2
-
38
-
-
0035021390
-
Dihydrotestosterone enhances transforming growth factor-beta-induced apoptosis in hormone-sensitive prostate cancer cells
-
Bruckheimer EM, Kyprianou N. Dihydrotestosterone enhances transforming growth factor-beta-induced apoptosis in hormone-sensitive prostate cancer cells. Endocrinology 2001;142:2419-26.
-
(2001)
Endocrinology
, vol.142
, pp. 2419-2426
-
-
Bruckheimer, E.M.1
Kyprianou, N.2
-
39
-
-
0036787491
-
Bcl-2 antagonizes the combined apoptotic effect of transforming growth factor-beta and dihydrotestosterone in prostate cancer cells
-
Bruckheimer EM, Kyprianou N. Bcl-2 antagonizes the combined apoptotic effect of transforming growth factor-beta and dihydrotestosterone in prostate cancer cells. Prostate 2002;53:133-42.
-
(2002)
Prostate
, vol.53
, pp. 133-142
-
-
Bruckheimer, E.M.1
Kyprianou, N.2
-
40
-
-
14044259321
-
Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling
-
Wang H, Song K, Sponseller TL, Danielpour D. Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling. J Biol Chem 2005;280: 5154-62.
-
(2005)
J Biol Chem
, vol.280
, pp. 5154-5162
-
-
Wang, H.1
Song, K.2
Sponseller, T.L.3
Danielpour, D.4
-
41
-
-
31644437977
-
Direct activation of TGF-beta1 transcription by androgen and androgen receptor complex in Huh7 human hepatoma cells and its tumor in nude mice
-
Yoon G, Kim JY, Choi YK, Won YS, Lim IK. Direct activation of TGF-beta1 transcription by androgen and androgen receptor complex in Huh7 human hepatoma cells and its tumor in nude mice. J Cell Biochem 2006;97:393-411.
-
(2006)
J Cell Biochem
, vol.97
, pp. 393-411
-
-
Yoon, G.1
Kim, J.Y.2
Choi, Y.K.3
Won, Y.S.4
Lim, I.K.5
-
42
-
-
0035266183
-
SMAD3 represses androgen receptor-mediated transcription
-
Hayes SA, Zarnegar M, Sharma M, Yang F, Peehl DM, ten Dijke P, et al. SMAD3 represses androgen receptor-mediated transcription. Cancer Res 2001;61:2112-8.
-
(2001)
Cancer Res
, vol.61
, pp. 2112-2118
-
-
Hayes, S.A.1
Zarnegar, M.2
Sharma, M.3
Yang, F.4
Peehl, D.M.5
Ten, D.P.6
-
43
-
-
77957345152
-
DHT selectively reverses Smad3-mediated/TGF-betainduced responses through transcriptional down-regulation of Smad3 in prostate epithelial cells
-
Song K, Wang H, Krebs TL, Wang B, Kelley TJ, Danielpour D. DHT selectively reverses Smad3-mediated/TGF-betainduced responses through transcriptional down-regulation of Smad3 in prostate epithelial cells. Mol Endocrinol 2010; 24:2019-29.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 2019-2029
-
-
Song, K.1
Wang, H.2
Krebs, T.L.3
Wang, B.4
Kelley, T.J.5
Danielpour, D.6
-
44
-
-
84863011667
-
Negative androgenresponse elements mediate androgen-dependent transcriptional inhibition of TGF-beta1 and CDK2 promoters in the prostate gland
-
Qi W, Gao S, Chu J, Zhou L, Wang Z. Negative androgenresponse elements mediate androgen-dependent transcriptional inhibition of TGF-beta1 and CDK2 promoters in the prostate gland. J Androl 2012;33:27-36.
-
(2012)
J Androl
, vol.33
, pp. 27-36
-
-
Qi, W.1
Gao, S.2
Chu, J.3
Zhou, L.4
Wang, Z.5
-
45
-
-
84881010495
-
Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion
-
Yu S, Xia S, Yang D, Wang K, Yeh S, Gao Z, et al. Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion. Med Oncol 2013;30:674.
-
(2013)
Med Oncol
, vol.30
, pp. 674
-
-
Yu, S.1
Xia, S.2
Yang, D.3
Wang, K.4
Yeh, S.5
Gao, Z.6
-
46
-
-
84905379640
-
Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer
-
Mishra S, Deng JJ, Gowda PS, Rao MK, Lin CL, Chen CL, et al. Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer. Oncogene 2014;33:4097-106.
-
(2014)
Oncogene
, vol.33
, pp. 4097-4106
-
-
Mishra, S.1
Deng, J.J.2
Gowda, P.S.3
Rao, M.K.4
Lin, C.L.5
Chen, C.L.6
-
47
-
-
33748059537
-
Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells
-
Ao M, Williams K, Bhowmick NA, Hayward SW. Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Res 2006;66:8007-16.
-
(2006)
Cancer Res
, vol.66
, pp. 8007-8016
-
-
Ao, M.1
Williams, K.2
Bhowmick, N.A.3
Hayward, S.W.4
-
48
-
-
30944466813
-
Smad3 is key to TGF-beta-mediated epithelialto- mesenchymal transition, fibrosis, tumor suppression and metastasis
-
Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, et al. Smad3 is key to TGF-beta-mediated epithelialto- mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev 2006;17(1-2): 19-27.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, Issue.1-2
, pp. 19-27
-
-
Roberts, A.B.1
Tian, F.2
Byfield, S.D.3
Stuelten, C.4
Ooshima, A.5
Saika, S.6
-
49
-
-
66449104669
-
Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo
-
Zhang X, Fournier MV, Ware JL, Bissell MJ, Yacoub A, Zehner ZE. Inhibition of vimentin or beta1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo. Mol Cancer Ther 2009;8:499-508.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 499-508
-
-
Zhang, X.1
Fournier, M.V.2
Ware, J.L.3
Bissell, M.J.4
Yacoub, A.5
Zehner, Z.E.6
-
50
-
-
66149171486
-
Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy
-
Zhang Q, Helfand BT, Jang TL, Zhu LJ, Chen L, Yang XJ, et al. Nuclear factor-kappaB-mediated transforming growth factor-beta-induced expression of vimentin is an independent predictor of biochemical recurrence after radical prostatectomy. Clin Cancer Res 2009;15:3557-67.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3557-3567
-
-
Zhang, Q.1
Helfand, B.T.2
Jang, T.L.3
Zhu, L.J.4
Chen, L.5
Yang, X.J.6
-
51
-
-
79960705270
-
TGF-beta1-induced EMT of nontransformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug
-
Slabáková E, Pernicová Z, Slaví čková E, Stařsíchová A, Kozubík A, Soucek K. TGF-beta1-induced EMT of nontransformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug. Prostate 2011;71:1332-43.
-
(2011)
Prostate
, vol.71
, pp. 1332-1343
-
-
Slabáková, E.1
Pernicová, Z.2
Slaví Čková, E.3
Stařsíchová, A.4
Kozubík, A.5
Soucek, K.6
-
52
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008;133:704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
-
53
-
-
66049105479
-
TGF-beta1 and TGF-beta2 strongly enhance the secretion of plasminogen activator inhibitor-1 and matrix metalloproteinase-9 of the human prostate cancer cell line PC-3
-
Konrad L, Scheiber JA, Schwarz L, Schrader AJ, Hofmann R. TGF-beta1 and TGF-beta2 strongly enhance the secretion of plasminogen activator inhibitor-1 and matrix metalloproteinase-9 of the human prostate cancer cell line PC-3. Regul Pept 2009;155(1-3):28-32.
-
(2009)
Regul Pept
, vol.155
, Issue.1-3
, pp. 28-32
-
-
Konrad, L.1
Scheiber, J.A.2
Schwarz, L.3
Schrader, A.J.4
Hofmann, R.5
-
54
-
-
84893090611
-
Regulation of crosstalk between epithelial to mesenchymal transition molecules and MMP-9 mediates the antimetastatic activity of anethole in DU145 prostate cancer cells
-
Ha B, Ko H, Kim B, Sohn EJ, Jung JH, Kim JS, et al. Regulation of crosstalk between epithelial to mesenchymal transition molecules and MMP-9 mediates the antimetastatic activity of anethole in DU145 prostate cancer cells. J Nat Prod 2014;77: 63-9.
-
(2014)
J Nat Prod
, vol.77
, pp. 63-69
-
-
Ha, B.1
Ko, H.2
Kim, B.3
Sohn, E.J.4
Jung, J.H.5
Kim, J.S.6
-
55
-
-
84880053006
-
Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus antiandrogen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis
-
Lin TH, Lee SO, Niu Y, Xu D, Liang L, Li L, et al. Differential androgen deprivation therapies with anti-androgens casodex/bicalutamide or MDV3100/Enzalutamide versus antiandrogen receptor ASC-J9(R) Lead to promotion versus suppression of prostate cancer metastasis. J Biol Chem 2013; 288:19359-69.
-
(2013)
J Biol Chem
, vol.288
, pp. 19359-19369
-
-
Lin, T.H.1
Lee, S.O.2
Niu, Y.3
Xu, D.4
Liang, L.5
Li, L.6
-
56
-
-
84879301158
-
Endothelial cells enhance prostate cancer metastasis via IL-6->androgen receptor->TGF-beta->MMP-9 signals
-
Wang X, Lee SO, Xia S, Jiang Q, Luo J, Li L, et al. Endothelial cells enhance prostate cancer metastasis via IL-6->androgen receptor->TGF-beta->MMP-9 signals. Mol Cancer Ther 2013; 12:1026-37.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 1026-1037
-
-
Wang, X.1
Lee, S.O.2
Xia, S.3
Jiang, Q.4
Luo, J.5
Li, L.6
-
57
-
-
84899586367
-
NEDD9 crucially regulates TGF-beta-triggered epithelial-mesenchymal transition and cell invasion in prostate cancer cells: Involvement in cancer progressiveness
-
Morimoto K, Tanaka T, Nitta Y, Ohnishi K, Kawashima H, Nakatani T. NEDD9 crucially regulates TGF-beta-triggered epithelial-mesenchymal transition and cell invasion in prostate cancer cells: involvement in cancer progressiveness. Prostate 2014;74:901-10.
-
(2014)
Prostate
, vol.74
, pp. 901-910
-
-
Morimoto, K.1
Tanaka, T.2
Nitta, Y.3
Ohnishi, K.4
Kawashima, H.5
Nakatani, T.6
-
58
-
-
84867568900
-
Clusterin mediates TGF-beta-induced epithelial- mesenchymal transition and metastasis via twist1 in prostate cancer cells
-
Shiota M, Zardan A, Takeuchi A, Kumano M, Beraldi E, Naito S, et al. Clusterin mediates TGF-beta-induced epithelial- mesenchymal transition and metastasis via twist1 in prostate cancer cells. Cancer Res 2012;72:5261-72.
-
(2012)
Cancer Res
, vol.72
, pp. 5261-5272
-
-
Shiota, M.1
Zardan, A.2
Takeuchi, A.3
Kumano, M.4
Beraldi, E.5
Naito, S.6
-
59
-
-
84869223265
-
The reactive stroma microenvironment and prostate cancer progression
-
Barron DA, Rowley DR. The reactive stroma microenvironment and prostate cancer progression. Endocr Relat Cancer 2012;19:R187-R204.
-
(2012)
Endocr Relat Cancer
, vol.19
, pp. R187-R204
-
-
Barron, D.A.1
Rowley, D.R.2
-
60
-
-
84925663696
-
Silibinin prevents prostate cancer cell-mediated differentiation of naive fibroblasts into cancer-associated fibroblast phenotype by targeting TGF beta2
-
Epub ahead of print
-
Ting HJ, Deep G, Jain AK, Cimic A, Sirintrapun J, Romero LM, et al. Silibinin prevents prostate cancer cell-mediated differentiation of naive fibroblasts into cancer-associated fibroblast phenotype by targeting TGF beta2. Mol Carcinog 2014http://dx.doi.org/10.1002/mc.22135 [Epub ahead of print].
-
(2014)
Mol Carcinog
-
-
Ting, H.J.1
Deep, G.2
Jain, A.K.3
Cimic, A.4
Sirintrapun, J.5
Romero, L.M.6
-
61
-
-
3242687911
-
Diagnosis and reporting of limited adenocarcinoma of the prostate on needle biopsy
-
Epstein JI. Diagnosis and reporting of limited adenocarcinoma of the prostate on needle biopsy. Mod Pathol 2004;17: 307-15.
-
(2004)
Mod Pathol
, vol.17
, pp. 307-315
-
-
Epstein, J.I.1
-
62
-
-
84904034743
-
Apigenin inhibits TGFbeta- induced VEGF expression in human prostate carcinoma cells via a Smad2/3- And Src-dependent mechanism
-
Mirzoeva S, Franzen CA, Pelling JC. Apigenin inhibits TGFbeta- induced VEGF expression in human prostate carcinoma cells via a Smad2/3- And Src-dependent mechanism. Mol Carcinog 2014;53:598-609.
-
(2014)
Mol Carcinog
, vol.53
, pp. 598-609
-
-
Mirzoeva, S.1
Franzen, C.A.2
Pelling, J.C.3
-
63
-
-
0842288323
-
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
-
Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S, et al. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 2004; 303:848-51.
-
(2004)
Science
, vol.303
, pp. 848-851
-
-
Bhowmick, N.A.1
Chytil, A.2
Plieth, D.3
Gorska, A.E.4
Dumont, N.5
Shappell, S.6
-
64
-
-
59649101847
-
Generation of mice with conditionally activated transforming growth factor beta signaling through the TbetaRI/ALK5 receptor
-
Bartholin L, Cyprian FS, Vincent D, Garcia CN, Martel S, Horvat B, et al. Generation of mice with conditionally activated transforming growth factor beta signaling through the TbetaRI/ALK5 receptor. Genesis 2008;46:724-31.
-
(2008)
Genesis
, vol.46
, pp. 724-731
-
-
Bartholin, L.1
Cyprian, F.S.2
Vincent, D.3
Garcia, C.N.4
Martel, S.5
Horvat, B.6
-
65
-
-
33748465396
-
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cellspecific targeting of transforming growth factor-beta receptor
-
Marie JC, Liggitt D, Rudensky AY. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cellspecific targeting of transforming growth factor-beta receptor. Immunity 2006;25:441-54.
-
(2006)
Immunity
, vol.25
, pp. 441-454
-
-
Marie, J.C.1
Liggitt, D.2
Rudensky, A.Y.3
-
66
-
-
79960451984
-
T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-beta1 cytokine
-
Donkor MK, Sarkar A, Savage PA, Franklin RA, Johnson LK, Jungbluth AA, et al. T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-beta1 cytokine. Immunity 2011;35:123-34.
-
(2011)
Immunity
, vol.35
, pp. 123-134
-
-
Donkor, M.K.1
Sarkar, A.2
Savage, P.A.3
Franklin, R.A.4
Johnson, L.K.5
Jungbluth, A.A.6
-
67
-
-
0037385330
-
Foxp3 programs the development and function of CD4CD25 regulatory T cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4CD25 regulatory T cells. Nat Immunol 2003;4:330-6.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
68
-
-
0348223787
-
Conversion of peripheral CD4CD25- naive T cells to CD4CD25 regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, et al. Conversion of peripheral CD4CD25- naive T cells to CD4CD25 regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003;198:1875-86.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
69
-
-
31944446597
-
Infiltration of tumor-reactive transforming growth factorbeta insensitive CD8 T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells
-
Zhang Q, Jang TL, Yang X, Park I, Meyer RE, Kundu S, et al. Infiltration of tumor-reactive transforming growth factorbeta insensitive CD8 T cells into the tumor parenchyma is associated with apoptosis and rejection of tumor cells. Prostate 2006;66:235-47.
-
(2006)
Prostate
, vol.66
, pp. 235-247
-
-
Zhang, Q.1
Jang, T.L.2
Yang, X.3
Park, I.4
Meyer, R.E.5
Kundu, S.6
-
70
-
-
84856955090
-
Modeling prostate cancer in mice: Limitations and opportunities
-
Hensley PJ, Kyprianou N. Modeling prostate cancer in mice: Limitations and opportunities. J Androl 2012;33:133-44.
-
(2012)
J Androl
, vol.33
, pp. 133-144
-
-
Hensley, P.J.1
Kyprianou, N.2
-
71
-
-
84859827014
-
Loss of TGF-beta responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions
-
Li X, Sterling JA, Fan KH, Vessella RL, Shyr Y, Hayward SW, et al. Loss of TGF-beta responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions. Mol Cancer Res 2012;10:494-503.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 494-503
-
-
Li, X.1
Sterling, J.A.2
Fan, K.H.3
Vessella, R.L.4
Shyr, Y.5
Hayward, S.W.6
-
72
-
-
0027416389
-
Transgenic models for the study of prostate cancer
-
Thompson TC, Truong LD, Timme TL, Kadmon D, McCune BK, Flanders KC, et al. Transgenic models for the study of prostate cancer. Cancer 1993;71(3 Suppl):1165-71.
-
(1993)
Cancer
, vol.71
, Issue.3
, pp. 1165-1171
-
-
Thompson, T.C.1
Truong, L.D.2
Timme, T.L.3
Kadmon, D.4
McCune, B.K.5
Flanders, K.C.6
-
73
-
-
79951512852
-
SMAD4- dependent barrier constrains prostate cancer growth and metastatic progression
-
Ding Z, Wu CJ, Chu GC, Xiao Y, Ho D, Zhang J, et al. SMAD4- dependent barrier constrains prostate cancer growth and metastatic progression. Nature 2011;470:269-73.
-
(2011)
Nature
, vol.470
, pp. 269-273
-
-
Ding, Z.1
Wu, C.J.2
Chu, G.C.3
Xiao, Y.4
Ho, D.5
Zhang, J.6
-
75
-
-
67349217954
-
First human dose escalation study in patients with metastatic malignancies to determine safety and pharmacokinetics of LY2157299, a small molecule inhibitor of the transforming growth factor-b receptor I kinase
-
Abstr
-
Calve-Aller E. First human dose escalation study in patients with metastatic malignancies to determine safety and pharmacokinetics of LY2157299, a small molecule inhibitor of the transforming growth factor-b receptor I kinase. ASCO Annu Meet J Clin Oncol 2008;26:14554. Abstr.
-
(2008)
ASCO Annu Meet J Clin Oncol
, vol.26
, pp. 14554
-
-
Calve-Aller, E.1
-
76
-
-
79956011495
-
A phase 1, single-dose study of fresolimumab, an anti-TGF-beta antibody, in treatment-resistant primary focal segmental glomerulosclerosis
-
Trachtman H, Fervenza FC, Gipson DS, Heering P, Jayne DR, Peters H, et al. A phase 1, single-dose study of fresolimumab, an anti-TGF-beta antibody, in treatment-resistant primary focal segmental glomerulosclerosis. Kidney Int 2011;79: 1236-43.
-
(2011)
Kidney Int
, vol.79
, pp. 1236-1243
-
-
Trachtman, H.1
Fervenza, F.C.2
Gipson, D.S.3
Heering, P.4
Jayne, D.R.5
Peters, H.6
-
78
-
-
0036086409
-
Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases
-
Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, et al. Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases. J Clin Invest 2002; 109:1551-9.
-
(2002)
J Clin Invest
, vol.109
, pp. 1551-1559
-
-
Muraoka, R.S.1
Dumont, N.2
Ritter, C.A.3
Dugger, T.C.4
Brantley, D.M.5
Chen, J.6
|