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Volumn 71, Issue 12, 2011, Pages 1332-1343

TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug

Author keywords

benign hyperplasia; epithelial mesenchymal transition; miR 200 family; Slug; transforming growth factor 1

Indexed keywords

BIOLOGICAL MARKER; MESSENGER RNA; MICRORNA; MICRORNA 200; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

EID: 79960705270     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21350     Document Type: Article
Times cited : (94)

References (46)
  • 1
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • Kalluri R, Weinberg RA,. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119 (6): 1420-1428.
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 2
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • Xu J, Lamouille S, Derynck R,. TGF-beta-induced epithelial to mesenchymal transition. Cell Res 2009; 19 (2): 156-172.
    • (2009) Cell Res , vol.19 , Issue.2 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 3
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • DOI 10.1242/jcs.00224
    • Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, Cano A,. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors. J Cell Sci 2003; 116 (Pt 3): 499-511. (Pubitemid 36231290)
    • (2003) Journal of Cell Science , vol.116 , Issue.3 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 4
    • 20144388095 scopus 로고    scopus 로고
    • DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
    • DOI 10.1038/sj.onc.1208429
    • Eger A, Aigner K, Sonderegger S, Dampier B, Oehler S, Schreiber M, Berx G, Cano A, Beug H, Foisner R,. DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene 2005; 24 (14): 2375-2385. (Pubitemid 40546696)
    • (2005) Oncogene , vol.24 , Issue.14 , pp. 2375-2385
    • Eger, A.1    Aigner, K.2    Sonderegger, S.3    Dampier, B.4    Oehler, S.5    Schreiber, M.6    Berx, G.7    Cano, A.8    Beug, H.9    Foisner, R.10
  • 9
    • 0035920152 scopus 로고    scopus 로고
    • A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
    • Perez-Moreno MA, Locascio A, Rodrigo I, Dhondt G, Portillo F, Nieto MA, Cano A,. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J Biol Chem 2001; 276 (29): 27424-27431.
    • (2001) J Biol Chem , vol.276 , Issue.29 , pp. 27424-27431
    • Perez-Moreno, M.A.1    Locascio, A.2    Rodrigo, I.3    Dhondt, G.4    Portillo, F.5    Nieto, M.A.6    Cano, A.7
  • 10
    • 77956262480 scopus 로고    scopus 로고
    • Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells
    • Lindley LE, Briegel KJ,. Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells. Biochem Biophys Res Commun 2010; 399 (4): 659-664.
    • (2010) Biochem Biophys Res Commun , vol.399 , Issue.4 , pp. 659-664
    • Lindley, L.E.1    Briegel, K.J.2
  • 11
    • 33748928159 scopus 로고    scopus 로고
    • The Diverse Functions of MicroRNAs in Animal Development and Disease
    • DOI 10.1016/j.devcel.2006.09.009, PII S1534580706004023
    • Kloosterman WP, Plasterk RH,. The diverse functions of microRNAs in animal development and disease. Dev Cell 2006; 11 (4): 441-450. (Pubitemid 44430905)
    • (2006) Developmental Cell , vol.11 , Issue.4 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.A.2
  • 13
    • 67650686848 scopus 로고    scopus 로고
    • The role of microRNAs in metastasis and epithelial-mesenchymal transition
    • Bracken CP, Gregory PA, Khew-Goodall Y, Goodall GJ,. The role of microRNAs in metastasis and epithelial-mesenchymal transition. Cell Mol Life Sci 2009; 6 (10): 1682-1699.
    • (2009) Cell Mol Life Sci , vol.6 , Issue.10 , pp. 1682-1699
    • Bracken, C.P.1    Gregory, P.A.2    Khew-Goodall, Y.3    Goodall, G.J.4
  • 14
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y,. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283 (22): 14910-14914.
    • (2008) J Biol Chem , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 15
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • DOI 10.1038/embor.2008.74, PII EMBOR200874
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz T,. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9 (6): 582-589. (Pubitemid 351772923)
    • (2008) EMBO Reports , vol.9 , Issue.6 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6    Brabletz, T.7
  • 16
    • 77956230322 scopus 로고    scopus 로고
    • The, ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?
    • Brabletz S, Brabletz T,. The, ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer? EMBO Rep 2010; 11 (9): 670-677.
    • (2010) EMBO Rep , vol.11 , Issue.9 , pp. 670-677
    • Brabletz, S.1    Brabletz, T.2
  • 17
    • 0028603343 scopus 로고
    • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type i receptors
    • Miettinen PJ, Ebner R, Lopez AR, Derynck R,. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: Involvement of type I receptors. J Cell Biol 1994; 127 (6 Pt 2): 2021-2036.
    • (1994) J Cell Biol , vol.127 , Issue.6 PART 2 , pp. 2021-2036
    • Miettinen, P.J.1    Ebner, R.2    Lopez, A.R.3    Derynck, R.4
  • 18
    • 74949093198 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer
    • Miyazono K,. Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85 (8): 314-323.
    • (2009) Proc Jpn Acad ser B Phys Biol Sci , vol.85 , Issue.8 , pp. 314-323
    • Miyazono, K.1
  • 19
    • 75649088874 scopus 로고    scopus 로고
    • Mechanisms of the epithelial-mesenchymal transition by TGF-beta
    • Wendt MK, Allington TM, Schiemann WP,. Mechanisms of the epithelial-mesenchymal transition by TGF-beta. Future Oncol 2009; 5 (8): 1145-1168.
    • (2009) Future Oncol , vol.5 , Issue.8 , pp. 1145-1168
    • Wendt, M.K.1    Allington, T.M.2    Schiemann, W.P.3
  • 20
    • 33746034613 scopus 로고    scopus 로고
    • Transforming growth factor-β employs HMGA2 to elicit epithelial-mesenchymal transition
    • DOI 10.1083/jcb.200512110
    • Thuault S, Valcourt U, Petersen M, Manfioletti G, Heldin CH, Moustakas A,. Transforming growth factor-beta employs HMGA2 to elicit epithelial- mesenchymal transition. J Cell Biol 2006; 174 (2): 175-183. (Pubitemid 44079853)
    • (2006) Journal of Cell Biology , vol.174 , Issue.2 , pp. 175-183
    • Thuault, S.1    Valcourt, U.2    Petersen, M.3    Manfioletti, G.4    Heldin, C.-H.5    Moustakas, A.6
  • 22
    • 30944466813 scopus 로고    scopus 로고
    • Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
    • DOI 10.1016/j.cytogfr.2005.09.008, PII S1359610105001127
    • Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, Flanders KC,. Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev 2006; 17 (1-2): 19-27. (Pubitemid 43117513)
    • (2006) Cytokine and Growth Factor Reviews , vol.17 , Issue.1-2 , pp. 19-27
    • Roberts, A.B.1    Tian, F.2    Byfield, S.D.3    Stuelten, C.4    Ooshima, A.5    Saika, S.6    Flanders, K.C.7
  • 24
    • 77955665703 scopus 로고    scopus 로고
    • TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells
    • Starsichova A, Lincova E, Pernicova Z, Kozubik A, Soucek K,. TGF-beta1 suppresses IL-6-induced STAT3 activation through regulation of Jak2 expression in prostate epithelial cells. Cell Signal 2010; 22 (11): 1734-1744.
    • (2010) Cell Signal , vol.22 , Issue.11 , pp. 1734-1744
    • Starsichova, A.1    Lincova, E.2    Pernicova, Z.3    Kozubik, A.4    Soucek, K.5
  • 26
    • 44949231424 scopus 로고    scopus 로고
    • T method
    • DOI 10.1038/nprot.2008.73, PII NPROT.2008.73
    • Schmittgen TD, Livak KJ,. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008; 3 (6): 1101-1108. (Pubitemid 351818697)
    • (2008) Nature Protocols , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 27
    • 77954862083 scopus 로고    scopus 로고
    • The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
    • Taylor MA, Parvani JG, Schiemann WP,. The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells. J Mammary Gland Biol Neoplasia 2010; 15 (2): 169-190.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 169-190
    • Taylor, M.A.1    Parvani, J.G.2    Schiemann, W.P.3
  • 28
    • 59849124087 scopus 로고    scopus 로고
    • Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer
    • Chu JH, Yu S, Hayward SW, Chan FL,. Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. Prostate 2009; 69 (4): 428-442.
    • (2009) Prostate , vol.69 , Issue.4 , pp. 428-442
    • Chu, J.H.1    Yu, S.2    Hayward, S.W.3    Chan, F.L.4
  • 29
    • 33748059537 scopus 로고    scopus 로고
    • Transforming growth factor-β promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells
    • DOI 10.1158/0008-5472.CAN-05-4451
    • Ao M, Williams K, Bhowmick NA, Hayward SW,. Transforming growth factor-{beta} promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Res 2006; 66 (16): 8007-8016. (Pubitemid 44299165)
    • (2006) Cancer Research , vol.66 , Issue.16 , pp. 8007-8016
    • Ao, M.1    Williams, K.2    Bhowmick, N.A.3    Hayward, S.W.4
  • 30
    • 78650310780 scopus 로고    scopus 로고
    • Epithelial plasticity, cancer stem cells and bone metastasis formation
    • van der Pluijm G,. Epithelial plasticity, cancer stem cells and bone metastasis formation. Bone 2011; 48 (1): 37-43.
    • (2011) Bone , vol.48 , Issue.1 , pp. 37-43
    • Van Der Pluijm, G.1
  • 32
    • 77957902732 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells
    • Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, Sarkar FH,. Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLoS ONE 2010; 5 (8): e12445.
    • (2010) PLoS ONE , vol.5 , Issue.8
    • Kong, D.1    Banerjee, S.2    Ahmad, A.3    Li, Y.4    Wang, Z.5    Sethi, S.6    Sarkar, F.H.7
  • 33
    • 26944435866 scopus 로고    scopus 로고
    • Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells
    • DOI 10.1677/erc.1.00958
    • Veveris-Lowe TL, Lawrence MG, Collard RL, Bui L, Herington AC, Nicol DL, Clements JA,. Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells. Endocr Relat Cancer 2005; 12 (3): 631-643. (Pubitemid 41482997)
    • (2005) Endocrine-Related Cancer , vol.12 , Issue.3 , pp. 631-643
    • Veveris-Lowe, T.L.1    Lawrence, M.G.2    Collard, R.L.3    Bui, L.4    Herington, A.C.5    Nicol, D.L.6    Clements, J.A.7
  • 34
    • 44449173164 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase induces epithelial-to- mesenchymal transition in prostate cancer
    • Cao J, Chiarelli C, Richman O, Zarrabi K, Kozarekar P, Zucker S,. Membrane type 1 matrix metalloproteinase induces epithelial-to-mesenchymal transition in prostate cancer. J Biol Chem 2008; 283 (10): 6232-6240.
    • (2008) J Biol Chem , vol.283 , Issue.10 , pp. 6232-6240
    • Cao, J.1    Chiarelli, C.2    Richman, O.3    Zarrabi, K.4    Kozarekar, P.5    Zucker, S.6
  • 36
    • 0029202881 scopus 로고
    • Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1
    • Hayward SW, Dahiya R, Cunha GR, Bartek J, Deshpande N, Narayan P,. Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1. In Vitro Cell Dev Biol Anim 1995; 31 (1): 14-24.
    • (1995) In Vitro Cell Dev Biol Anim , vol.31 , Issue.1 , pp. 14-24
    • Hayward, S.W.1    Dahiya, R.2    Cunha, G.R.3    Bartek, J.4    Deshpande, N.5    Narayan, P.6
  • 37
    • 16844379257 scopus 로고    scopus 로고
    • Cadherin switching: Essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition
    • DOI 10.1242/jcs.01634
    • Maeda M, Johnson KR, Wheelock MJ,. Cadherin switching: Essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition. J Cell Sci 2005; 118 (Pt 5): 873-887. (Pubitemid 40484880)
    • (2005) Journal of Cell Science , vol.118 , Issue.5 , pp. 873-887
    • Maeda, M.1    Johnson, K.R.2    Wheelock, M.J.3
  • 38
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of β-catenin signaling, Slug, and MAPK
    • DOI 10.1083/jcb.200308162
    • Conacci-Sorrell M, Simcha I, Ben-Yedidia T, Blechman J, Savagner P, Ben-Ze'ev A,. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug, and MAPK. J Cell Biol 2003; 163 (4): 847-857. (Pubitemid 37517891)
    • (2003) Journal of Cell Biology , vol.163 , Issue.4 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3    Blechman, J.4    Savagner, P.5    Ben-Ze'Ev, A.6
  • 39
    • 0033835249 scopus 로고    scopus 로고
    • Time at confluence for human RPE cells: Effects on the adherens junction and in vitro wound closure
    • Kaida M, Cao F, Skumatz CM, Irving PE, Burke JM,. Time at confluence for human RPE cells: Effects on the adherens junction and in vitro wound closure. Invest Ophthalmol Vis Sci 2000; 41 (10): 3215-3224.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.10 , pp. 3215-3224
    • Kaida, M.1    Cao, F.2    Skumatz, C.M.3    Irving, P.E.4    Burke, J.M.5
  • 40
    • 66349094564 scopus 로고    scopus 로고
    • Cell-cell contact globally activates microRNA biogenesis
    • Hwang HW, Wentzel EA, Mendell JT,. Cell-cell contact globally activates microRNA biogenesis. Proc Natl Acad Sci USA 2009; 106 (17): 7016-7021.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.17 , pp. 7016-7021
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 41
    • 67549101912 scopus 로고    scopus 로고
    • Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus
    • Zhang C, Klymkowsky MW,. Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Dev Biol 2009; 331 (2): 340-349.
    • (2009) Dev Biol , vol.331 , Issue.2 , pp. 340-349
    • Zhang, C.1    Klymkowsky, M.W.2
  • 42
    • 69349087756 scopus 로고    scopus 로고
    • MiR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy
    • Adam L, Zhong M, Choi W, Qi W, Nicoloso M, Arora A, Calin G, Wang H, Siefker-Radtke A, McConkey D, Bar-Eli M, Dinney C,. miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin Cancer Res 2009; 15 (16): 5060-5072.
    • (2009) Clin Cancer Res , vol.15 , Issue.16 , pp. 5060-5072
    • Adam, L.1    Zhong, M.2    Choi, W.3    Qi, W.4    Nicoloso, M.5    Arora, A.6    Calin, G.7    Wang, H.8    Siefker-Radtke, A.9    McConkey, D.10    Bar-Eli, M.11    Dinney, C.12
  • 44
    • 70450263322 scopus 로고    scopus 로고
    • The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion
    • Sossey-Alaoui K, Bialkowska K, Plow EF,. The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion. J Biol Chem 2009; 284 (48): 33019-33029.
    • (2009) J Biol Chem , vol.284 , Issue.48 , pp. 33019-33029
    • Sossey-Alaoui, K.1    Bialkowska, K.2    Plow, E.F.3
  • 45
    • 77957280345 scopus 로고    scopus 로고
    • Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in nonosmall cell lung cancer
    • Ceppi P, Mudduluru G, Kumarswamy R, Rapa I, Scagliotti GV, Papotti M, Allgayer H,. Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in nonosmall cell lung cancer. Mol Cancer Res 2010; 8 (9): 1207-1216.
    • (2010) Mol Cancer Res , vol.8 , Issue.9 , pp. 1207-1216
    • Ceppi, P.1    Mudduluru, G.2    Kumarswamy, R.3    Rapa, I.4    Scagliotti, G.V.5    Papotti, M.6    Allgayer, H.7
  • 46
    • 69249156944 scopus 로고    scopus 로고
    • MiR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells
    • Kong D, Li Y, Wang Z, Banerjee S, Ahmad A, Kim HRC, Sarkar FH,. miR-200 regulates PDGF-D-mediated epithelial-mesenchymal transition, adhesion, and invasion of prostate cancer cells. Stem Cells 2009; 27 (8): 1712-1721.
    • (2009) Stem Cells , vol.27 , Issue.8 , pp. 1712-1721
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Ahmad, A.5    Kim, H.R.C.6    Sarkar, F.H.7


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