TRAF6 ubiquitinates TGFβ type i receptor to promote its cleavage and nuclear translocation in cancer

Nature Communications

Volumn 2, Issue 1, 2011, Pages

  Mu, Yabing ^a,b   Sundar, Reshma ^a,c   Thakur, Noopur ^a,b   Ekman, Maria ^b   Gudey, Shyam Kumar ^a,b   Yakymovych, Mariya ^b   Hermansson, Annika ^a   Dimitriou, Helen ^a,d   Bengoechea Alonso, Maria Teresa ^b,e   Ericsson, Johan ^b,e   Heldin, Carl Henrik ^b   Landström, Marene ^a,b,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UMEÅ UNIVERSITY   (Sweden)

^d UNIVERSITY OF CRETE   (Greece)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; LYSINE; POLYUBIQUITIN; PROTEIN KINASE C ZETA; PROTEIN P300; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; ADAM PROTEIN; E1A ASSOCIATED P300 PROTEIN; EP300 PROTEIN, HUMAN; ISOENZYME; MMP2 PROTEIN, HUMAN; PROTEIN KINASE C; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ARTICLE; CANCER CELL; CANCER INVASION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE ACTIVATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MALE; NEOPLASM; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN LOCALIZATION; TRANSCRIPTION REGULATION; UBIQUITINATION; ACTIVE TRANSPORT; ANIMAL; CELL CULTURE; CHEMISTRY; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

GASTROPODA;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAM PROTEINS; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CELLS, CULTURED; E1A-ASSOCIATED P300 PROTEIN; HUMANS; ISOENZYMES; MATRIX METALLOPROTEINASE 2; MICE; NEOPLASM INVASIVENESS; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; UBIQUITINATION;

EID: 79958698402     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms1332     Document Type: Article

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