TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: A retrospective study

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Bacman, David ^a   Merkel, Susanne ^a   Croner, Roland ^a   Papadopoulos, Thomas ^a   Brueckl, Wolfgang ^a   Dimmler, Arno ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b St Vincentius Hospital   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD68 ANTIGEN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; PROTEIN SERINE THREONINE KINASE; TGF BETA TYPE I RECEPTOR; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER STAGING; COLON CARCINOMA; COLON RESECTION; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; PHENOTYPE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; SURVIVAL TIME; TISSUE MICROARRAY; TUMOR ASSOCIATED LEUKOCYTE; TUMOR DIFFERENTIATION; CANCER INVASION; COLON TUMOR; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; LYMPH NODE; MACROPHAGE; METABOLISM; MIDDLE AGED; PATHOLOGY; STROMA CELL; SURVIVAL RATE;

ADULT; AGED; AGED, 80 AND OVER; COLONIC NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPH NODES; LYMPHATIC METASTASIS; MACROPHAGES; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RETROSPECTIVE STUDIES; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; SMAD4 PROTEIN; STROMAL CELLS; SURVIVAL RATE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MARKERS, BIOLOGICAL;

EID: 34748819999     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-156     Document Type: Article

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