-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
J. Ferlay, H.R. Shin, F. Bray, D. Forman, C. Mathers, and D.M. Parkin Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 Int J Cancer 127 2010 2893 2917
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
84860266865
-
International variation in prostate cancer incidence and mortality rates
-
M.M. Center, A. Jemal, and J. Lortet-Tieulent et al. International variation in prostate cancer incidence and mortality rates Eur Urol 61 2012 1079 1092
-
(2012)
Eur Urol
, vol.61
, pp. 1079-1092
-
-
Center, M.M.1
Jemal, A.2
Lortet-Tieulent, J.3
-
3
-
-
1042269786
-
Effect of orchiectomy and irradiation on cancer of the prostate
-
C. Huggins Effect of orchiectomy and irradiation on cancer of the prostate Ann Surg 115 1942 1192 1200
-
(1942)
Ann Surg
, vol.115
, pp. 1192-1200
-
-
Huggins, C.1
-
4
-
-
46749099444
-
Castration-recurrent prostate cancer is not androgen-independent
-
J.L. Mohler Castration-recurrent prostate cancer is not androgen-independent Adv Exp Med Biol 617 2008 223 234
-
(2008)
Adv Exp Med Biol
, vol.617
, pp. 223-234
-
-
Mohler, J.L.1
-
5
-
-
42949165515
-
A role for the androgen-receptor in clinically localized and advanced prostate cancer
-
J.L. Mohler A role for the androgen-receptor in clinically localized and advanced prostate cancer Best Pract Res Clin Endocrinol Metab 22 2008 357 372
-
(2008)
Best Pract Res Clin Endocrinol Metab
, vol.22
, pp. 357-372
-
-
Mohler, J.L.1
-
6
-
-
84867663093
-
Biology of castration-recurrent prostate cancer
-
F. Azzouni, and J. Mohler Biology of castration-recurrent prostate cancer Urol Clin North Am 39 2012 435 452
-
(2012)
Urol Clin North Am
, vol.39
, pp. 435-452
-
-
Azzouni, F.1
Mohler, J.2
-
7
-
-
70349395222
-
Anti-androgens and androgen-depleting therapies in prostate cancer: New agents for an established target
-
Y. Chen, N.J. Clegg, and H.I. Scher Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target Lancet Oncol 10 2009 981 991
-
(2009)
Lancet Oncol
, vol.10
, pp. 981-991
-
-
Chen, Y.1
Clegg, N.J.2
Scher, H.I.3
-
8
-
-
0029058770
-
Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): Potential agents for the treatment of prostatic cancer
-
G.A. Potter, S.E. Barrie, M. Jarman, and M.G. Rowlands Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer J Med Chem 38 1995 2463 2471
-
(1995)
J Med Chem
, vol.38
, pp. 2463-2471
-
-
Potter, G.A.1
Barrie, S.E.2
Jarman, M.3
Rowlands, M.G.4
-
9
-
-
0030925281
-
Biochemistry and pharmacokinetics of potent non-steroidal cytochrome P450(17alpha) inhibitors
-
S.E. Barrie, B.P. Haynes, and G.A. Potter et al. Biochemistry and pharmacokinetics of potent non-steroidal cytochrome P450(17alpha) inhibitors J Steroid Biochem Mol Biol 60 1997 347 351
-
(1997)
J Steroid Biochem Mol Biol
, vol.60
, pp. 347-351
-
-
Barrie, S.E.1
Haynes, B.P.2
Potter, G.A.3
-
10
-
-
0032585605
-
The 16,17-double bond is needed for irreversible inhibition of human cytochrome p45017alpha by abiraterone (17-(3-pyridyl)androsta-5, 16-dien-3beta-ol) and related steroidal inhibitors
-
M. Jarman, S.E. Barrie, and J.M. Llera The 16,17-double bond is needed for irreversible inhibition of human cytochrome p45017alpha by abiraterone (17-(3-pyridyl)androsta-5, 16-dien-3beta-ol) and related steroidal inhibitors J Med Chem 41 1998 5375 5381
-
(1998)
J Med Chem
, vol.41
, pp. 5375-5381
-
-
Jarman, M.1
Barrie, S.E.2
Llera, J.M.3
-
11
-
-
53749090666
-
Phase i clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
G. Attard, A.H. Reid, and T.A. Yap et al. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven J Clin Oncol 26 2008 4563 4571
-
(2008)
J Clin Oncol
, vol.26
, pp. 4563-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
-
12
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
J.S. de Bono, C.J. Logothetis, and A. Molina et al. Abiraterone and increased survival in metastatic prostate cancer N Engl J Med 364 2011 1995 2005
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
13
-
-
79960435644
-
Phase II study of abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer displaying bone flare discordant with serologic response
-
C.J. Ryan, S. Shah, and E. Efstathiou et al. Phase II study of abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer displaying bone flare discordant with serologic response Clin Cancer Res 17 2011 4854 4861
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4854-4861
-
-
Ryan, C.J.1
Shah, S.2
Efstathiou, E.3
-
14
-
-
84870243969
-
Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: Exploratory analysis of data from the COU-AA-301 randomised trial
-
C.J. Logothetis, E. Basch, and A. Molina et al. Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial Lancet Oncol 13 2012 1210 1217
-
(2012)
Lancet Oncol
, vol.13
, pp. 1210-1217
-
-
Logothetis, C.J.1
Basch, E.2
Molina, A.3
-
15
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
C.J. Ryan, M.R. Smith, and J.S. de Bono et al. Abiraterone in metastatic prostate cancer without previous chemotherapy N Engl J Med 368 2013 138 148
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
-
16
-
-
84879901733
-
Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy [abstract 5]
-
D. Rathkopf, M. Smith, and J. De Bono et al. Updated interim analysis (IA) of COU-AA-302, a randomized phase III study of abiraterone acetate (AA) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) without prior chemotherapy [abstract 5] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Rathkopf, D.1
Smith, M.2
De Bono, J.3
-
17
-
-
84866909023
-
Effect of neoadjuvant abiraterone acetate (AA) plus leuprolide acetate (LHRHa) on PSA, pathological complete response (pCR), and near pCR in localized high-risk prostate cancer (LHRPC): Results of a randomized phase II study [abstract 4521]
-
M.E. Taplin, R.B. Montgomery, and C. Logothetis et al. Effect of neoadjuvant abiraterone acetate (AA) plus leuprolide acetate (LHRHa) on PSA, pathological complete response (pCR), and near pCR in localized high-risk prostate cancer (LHRPC): results of a randomized phase II study [abstract 4521] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Taplin, M.E.1
Montgomery, R.B.2
Logothetis, C.3
-
18
-
-
84856780403
-
Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer
-
T. Kaku, T. Hitaka, and A. Ojida et al. Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer Bioorg Med Chem 19 2011 6383 6399
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 6383-6399
-
-
Kaku, T.1
Hitaka, T.2
Ojida, A.3
-
19
-
-
84870366365
-
Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats
-
T. Hara, J. Kouno, and T. Kaku et al. Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats J Steroid Biochem Mol Biol 134 2013 80 91
-
(2013)
J Steroid Biochem Mol Biol
, vol.134
, pp. 80-91
-
-
Hara, T.1
Kouno, J.2
Kaku, T.3
-
20
-
-
84891825980
-
A phase I/II study of safety and efficacy of orteronel (TAK-700), an oral, investigational, nonsteroidal 17,20-lyase inhibitor, with docetaxel and prednisone (DP) in metastatic castration-resistant prostate cancer (mCRPC): Updated phase II results [abstract 59]
-
D.P. Petrylak, J.G. Gandhi, and W.R. Clark et al. A phase I/II study of safety and efficacy of orteronel (TAK-700), an oral, investigational, nonsteroidal 17,20-lyase inhibitor, with docetaxel and prednisone (DP) in metastatic castration-resistant prostate cancer (mCRPC): updated phase II results [abstract 59] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Petrylak, D.P.1
Gandhi, J.G.2
Clark, W.R.3
-
21
-
-
84867615161
-
A phase III, randomized, double-blind, multicenter trial comparing the investigational agent orteronel (TAK-700) plus prednisone (P) with placebo plus P in patients with metastatic castration-resistant prostate cancer (mCRPC) that has progressed during or following docetaxel-based therapy [abstract TPS4693]
-
R. Dreicer, D. Agus, and J. Bellmunt et al. A phase III, randomized, double-blind, multicenter trial comparing the investigational agent orteronel (TAK-700) plus prednisone (P) with placebo plus P in patients with metastatic castration-resistant prostate cancer (mCRPC) that has progressed during or following docetaxel-based therapy [abstract TPS4693] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Dreicer, R.1
Agus, D.2
Bellmunt, J.3
-
22
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
H.I. Scher, T.M. Beer, and C.S. Higano et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study Lancet 375 2010 1437 1446
-
(2010)
Lancet
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
-
23
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
H.I. Scher, K. Fizazi, and F. Saad et al. Increased survival with enzalutamide in prostate cancer after chemotherapy N Engl J Med 367 2012 1187 1197
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
24
-
-
84891828553
-
TERRAIN: A randomized, double-blind, phase II study comparing MDV3100 with bicalutamide (Bic) in men with metastatic castrate-resistant prostate cancer (CRPC) [abstract TPS4698]
-
E.S. Baskin-Bey, N.D. Shore, K. Barber, T. Ouatas, and A. Heidenreich TERRAIN: a randomized, double-blind, phase II study comparing MDV3100 with bicalutamide (Bic) in men with metastatic castrate-resistant prostate cancer (CRPC) [abstract TPS4698] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Baskin-Bey, E.S.1
Shore, N.D.2
Barber, K.3
Ouatas, T.4
Heidenreich, A.5
-
25
-
-
84891829320
-
A randomized, open-label, phase II study of MDV3100 alone or in combination with leuprolide and dutasteride as neoadjuvant therapy to prostatectomy in intermediate and high-risk prostate cancer [abstract TPS4695]
-
R.B. Montgomery, A. Joshua, and A.L. Hannah et al. A randomized, open-label, phase II study of MDV3100 alone or in combination with leuprolide and dutasteride as neoadjuvant therapy to prostatectomy in intermediate and high-risk prostate cancer [abstract TPS4695] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Montgomery, R.B.1
Joshua, A.2
Hannah, A.L.3
-
26
-
-
84863230424
-
ARN-509: A novel antiandrogen for prostate cancer treatment
-
N.J. Clegg, J. Wongvipat, and J.D. Joseph et al. ARN-509: a novel antiandrogen for prostate cancer treatment Cancer Res 72 2012 1494 1503
-
(2012)
Cancer Res
, vol.72
, pp. 1494-1503
-
-
Clegg, N.J.1
Wongvipat, J.2
Joseph, J.D.3
-
27
-
-
84891826988
-
A phase II study of the androgen signaling inhibitor ARN-509 in patients with castration-resistant prostate cancer (CRPC) [abstract TPS4697]
-
D. Rathkopf, N.D. Shore, and E.S. Antonarakis et al. A phase II study of the androgen signaling inhibitor ARN-509 in patients with castration-resistant prostate cancer (CRPC) [abstract TPS4697] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Rathkopf, D.1
Shore, N.D.2
Antonarakis, E.S.3
-
28
-
-
80052705344
-
Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): Head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model
-
R.D. Bruno, T.S. Vasaitis, and L.K. Gediya et al. Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model Steroids 76 2011 1268 1279
-
(2011)
Steroids
, vol.76
, pp. 1268-1279
-
-
Bruno, R.D.1
Vasaitis, T.S.2
Gediya, L.K.3
-
29
-
-
84891826086
-
Phase i clinical trial of galeterone (TOK-001), a multifunctional antiandrogen and CYP17 inhibitor in castration resistant prostate cancer (CRPC) [abstract 4665]
-
R.B. Montgomery, M.A. Eisenberger, and M. Rettig et al. Phase I clinical trial of galeterone (TOK-001), a multifunctional antiandrogen and CYP17 inhibitor in castration resistant prostate cancer (CRPC) [abstract 4665] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Montgomery, R.B.1
Eisenberger, M.A.2
Rettig, M.3
-
30
-
-
80055122242
-
A population-based study of prostate cancer chemotherapy
-
V. Harris, K. Lloyd, S. Forsey, P. Rogers, M. Roche, and C. Parker A population-based study of prostate cancer chemotherapy Clin Oncol 23 2011 706 708
-
(2011)
Clin Oncol
, vol.23
, pp. 706-708
-
-
Harris, V.1
Lloyd, K.2
Forsey, S.3
Rogers, P.4
Roche, M.5
Parker, C.6
-
31
-
-
8944220720
-
Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: A Canadian randomized trial with palliative end points
-
I.F. Tannock, D. Osoba, and M.R. Stockler et al. Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points J Clin Oncol 14 1996 1756 1764
-
(1996)
J Clin Oncol
, vol.14
, pp. 1756-1764
-
-
Tannock, I.F.1
Osoba, D.2
Stockler, M.R.3
-
32
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
I.F. Tannock, R. de Wit, and W.R. Berry et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer N Engl J Med 351 2004 1502 1512
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
De Wit, R.2
Berry, W.R.3
-
33
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
D.P. Petrylak, C.M. Tangen, and M.H. Hussain et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer N Engl J Med 351 2004 1513 1520
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
-
34
-
-
77950562879
-
A review of the patterns of docetaxel use for hormone-resistant prostate cancer at the Princess Margaret Hospital
-
S.N. Chin, L. Wang, M. Moore, and S.S. Sridhar A review of the patterns of docetaxel use for hormone-resistant prostate cancer at the Princess Margaret Hospital Curr Oncol 17 2010 24 29
-
(2010)
Curr Oncol
, vol.17
, pp. 24-29
-
-
Chin, S.N.1
Wang, L.2
Moore, M.3
Sridhar, S.S.4
-
35
-
-
59449102526
-
Phase i and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
A.C. Mita, L.J. Denis, and E.K. Rowinsky et al. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors Clin Cancer Res 15 2009 723 730
-
(2009)
Clin Cancer Res
, vol.15
, pp. 723-730
-
-
Mita, A.C.1
Denis, L.J.2
Rowinsky, E.K.3
-
36
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
J.S. de Bono, S. Oudard, and M. Ozguroglu et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial Lancet 376 2010 1147 1154
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
De Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
-
37
-
-
84857603033
-
A subgr oup analysis of the TROPIC trial exploring reason for discontinuation of prior docetaxel and survival outcome of cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) [abstract 4526]
-
J. De Bono, S. Oudard, and M. Ozguroglu et al. A subgr oup analysis of the TROPIC trial exploring reason for discontinuation of prior docetaxel and survival outcome of cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) [abstract 4526] J Clin Oncol 29 Suppl 2011
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
De Bono, J.1
Oudard, S.2
Ozguroglu, M.3
-
38
-
-
84863840309
-
Impact of G-CSF prophylaxis on the occurrence of neutropenia in patients with metastatic castration-resistant prostate cancer (mCRPC) receiving cabazitaxel [abstract15131]
-
M. Ozguroglu, S. Oudard, and A.O. Sartor et al. Impact of G-CSF prophylaxis on the occurrence of neutropenia in patients with metastatic castration-resistant prostate cancer (mCRPC) receiving cabazitaxel [abstract15131] J Clin Oncol 29 Suppl 2011
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Ozguroglu, M.1
Oudard, S.2
Sartor, A.O.3
-
39
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
P.W. Kantoff, C.S. Higano, and N.D. Shore et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer N Engl J Med 363 2010 411 422
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
40
-
-
34447123763
-
Granulocyte macrophage colony-stimulating factor - Secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancer
-
E.J. Small, N. Sacks, and J. Nemunaitis et al. Granulocyte macrophage colony-stimulating factor - secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancer Clin Cancer Res 13 2007 3883 3891
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3883-3891
-
-
Small, E.J.1
Sacks, N.2
Nemunaitis, J.3
-
41
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
C.S. Higano, P.F. Schellhammer, and E.J. Small et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer Cancer 115 2009 3670 3679
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
-
42
-
-
30544449854
-
A phase i trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer
-
R.S. DiPaola, M. Plante, and H. Kaufman et al. A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer J Transl Med 4 2006 1
-
(2006)
J Transl Med
, vol.4
, pp. 1
-
-
Dipaola, R.S.1
Plante, M.2
Kaufman, H.3
-
43
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial of a poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
-
P.W. Kantoff, T.J. Schuetz, and B.A. Blumenstein et al. Overall survival analysis of a phase II randomized controlled trial of a poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer J Clin Oncol 28 2010 1099 1105
-
(2010)
J Clin Oncol
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
-
44
-
-
84880508629
-
Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: Results from an open-label, multicenter phase I/II study
-
S.F. Slovin, C.S. Higano, and O. Hamid et al. Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study Ann Oncol 24 2013 1813 1821
-
(2013)
Ann Oncol
, vol.24
, pp. 1813-1821
-
-
Slovin, S.F.1
Higano, C.S.2
Hamid, O.3
-
45
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
Y. Agata, A. Kawasaki, and H. Nishimura et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes Int Immunol 8 1996 765 772
-
(1996)
Int Immunol
, vol.8
, pp. 765-772
-
-
Agata, Y.1
Kawasaki, A.2
Nishimura, H.3
-
46
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
S.L. Topalian, F.S. Hodi, and J.R. Brahmer et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer N Engl J Med 366 2012 2443 2454
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
47
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
J.R. Brahmer, S.S. Tykodi, and L.Q. Chow et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer N Engl J Med 366 2012 2455 2465
-
(2012)
N Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
-
48
-
-
71249088083
-
Alpharadin, a 223Ra-based alpha-particle-emitting pharmaceutical for the treatment of bone metastases in patients with cancer
-
K. Liepe Alpharadin, a 223Ra-based alpha-particle-emitting pharmaceutical for the treatment of bone metastases in patients with cancer Curr Opin Investig Drugs 10 2009 1346 1358
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 1346-1358
-
-
Liepe, K.1
-
49
-
-
84860854128
-
Overall survival benefit and safety profile of radium-223 chloride, a first-in-class alpha-pharmaceutical: Results from a phase III randomized trial (ALSYMPCA) in patients with castration-resistant prostate cancer (CRPC) with bone metastases [abstract 8]
-
C. Parker, D. Heinrich, and J.M. O'Sullivan et al. Overall survival benefit and safety profile of radium-223 chloride, a first-in-class alpha-pharmaceutical: results from a phase III randomized trial (ALSYMPCA) in patients with castration-resistant prostate cancer (CRPC) with bone metastases [abstract 8] J Clin Oncol 30 Suppl 5 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL. 5
-
-
Parker, C.1
Heinrich, D.2
O'Sullivan, J.M.3
-
50
-
-
84861690508
-
Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401
-
W.K. Kelly, S. Halabi, and M. Carducci et al. Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401 J Clin Oncol 30 2012 1534 1540
-
(2012)
J Clin Oncol
, vol.30
, pp. 1534-1540
-
-
Kelly, W.K.1
Halabi, S.2
Carducci, M.3
-
51
-
-
84891830103
-
A phase 3 study to evaluate the efficacy and safety of docetaxel and prednisone (DP) with or without lenalidomide (LEN) in patients with castrate-resistant prostate cancer (CRPC): The MAINSAIL trial [abstract LBA24]
-
September 28-October 2, 2012; Vienna, Austria
-
D.P. Petrylak, K. Fizazi, and C.N. Sternberg et al. A phase 3 study to evaluate the efficacy and safety of docetaxel and prednisone (DP) with or without lenalidomide (LEN) in patients with castrate-resistant prostate cancer (CRPC): the MAINSAIL trial [abstract LBA24] Paper presented at: Meeting of the European Society of Medical Oncology September 28-October 2, 2012; Vienna, Austria 2012
-
(2012)
Paper Presented At: Meeting of the European Society of Medical Oncology
-
-
Petrylak, D.P.1
Fizazi, K.2
Sternberg, C.N.3
-
52
-
-
84879786803
-
Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): A phase 3, double-blind randomised trial
-
I.F. Tannock, K. Fizazi, and S. Ivanov et al. Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): a phase 3, double-blind randomised trial Lancet Oncol 14 2013 760 768
-
(2013)
Lancet Oncol
, vol.14
, pp. 760-768
-
-
Tannock, I.F.1
Fizazi, K.2
Ivanov, S.3
-
53
-
-
84876283322
-
Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): Results from the randomized phase III READY trial [abstract LBA8]
-
J.C. Araujo, G.C. Trudel, and F. Saad et al. Overall survival (OS) and safety of dasatinib/docetaxel versus docetaxel in patients with metastatic castration-resistant prostate cancer (mCRPC): results from the randomized phase III READY trial [abstract LBA8] J Clin Oncol 31 Suppl 6 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL. 6
-
-
Araujo, J.C.1
Trudel, G.C.2
Saad, F.3
-
54
-
-
70349926513
-
A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer (CRPC) [abstract 7]
-
E.J. Small, T. Demkow, and W.R. Gerritsen et al. A phase III trial of GVAX immunotherapy for prostate cancer in combination with docetaxel versus docetaxel plus prednisone in symptomatic, castration-resistant prostate cancer (CRPC) [abstract 7] J Clin Oncol Suppl 2009
-
(2009)
J Clin Oncol
, Issue.SUPPL.
-
-
Small, E.J.1
Demkow, T.2
Gerritsen, W.R.3
-
55
-
-
79957953692
-
Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer
-
H.I. Scher, X. Jia, and K. Chi et al. Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer J Clin Oncol 29 2011 2191 2198
-
(2011)
J Clin Oncol
, vol.29
, pp. 2191-2198
-
-
Scher, H.I.1
Jia, X.2
Chi, K.3
-
56
-
-
84891831295
-
SWOG S0421: Phase III study of docetaxel (D) and atrasentan (A) versus docetaxel and placebo (P) for men with advanced castrate resistant prostate cancer (CRPC) [abstract 4511]
-
D. Quinn, C.M. Tangen, and M. Hussain et al. SWOG S0421: phase III study of docetaxel (D) and atrasentan (A) versus docetaxel and placebo (P) for men with advanced castrate resistant prostate cancer (CRPC) [abstract 4511] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Quinn, D.1
Tangen, C.M.2
Hussain, M.3
-
57
-
-
84879466638
-
Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer
-
K.S. Fizazi, C.S. Higano, and J.B. Nelson et al. Phase III, randomized, placebo-controlled study of docetaxel in combination with zibotentan in patients with metastatic castration-resistant prostate cancer J Clin Oncol 31 2013 1740 1747
-
(2013)
J Clin Oncol
, vol.31
, pp. 1740-1747
-
-
Fizazi, K.S.1
Higano, C.S.2
Nelson, J.B.3
-
58
-
-
81255175385
-
Randomized, placebo-controlled, phase III trial of sunitinib in combination with prednisone (SU+P) versus prednisone (P) alone in men with progressive metastatic castration-resistant prostate cancer (mCRPC) [abstract 4515]
-
M.D. Michaelson, S. Oudard, and Y. Ou et al. Randomized, placebo-controlled, phase III trial of sunitinib in combination with prednisone (SU+P) versus prednisone (P) alone in men with progressive metastatic castration-resistant prostate cancer (mCRPC) [abstract 4515] J Clin Oncol 29 Suppl 2011
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Michaelson, M.D.1
Oudard, S.2
Ou, Y.3
-
59
-
-
83355166909
-
Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
-
F.M. Yakes, J. Chen, and J. Tan et al. Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth Mol Cancer Ther 10 2011 2298 2308
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 2298-2308
-
-
Yakes, F.M.1
Chen, J.2
Tan, J.3
-
60
-
-
84874787799
-
Cabozantinib in patients with advanced prostate cancer: Results of a phase II randomized discontinuation trial
-
D.C. Smith, M.R. Smith, and C. Sweeney et al. Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial J Clin Oncol 31 2013 412 419
-
(2013)
J Clin Oncol
, vol.31
, pp. 412-419
-
-
Smith, D.C.1
Smith, M.R.2
Sweeney, C.3
-
61
-
-
84867676575
-
Tasquinimod and survival in men with metastatic castration-resistant prostate cancer: Results of long-term follow-up of a randomized phase II placebo-controlled trial [abstract 4550]
-
A.J. Armstrong, M. Haggman, and W.M. Stadler et al. Tasquinimod and survival in men with metastatic castration-resistant prostate cancer: results of long-term follow-up of a randomized phase II placebo-controlled trial [abstract 4550] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Armstrong, A.J.1
Haggman, M.2
Stadler, W.M.3
-
62
-
-
77957957234
-
Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer
-
K.N. Chi, S.J. Hotte, and E.Y. Yu et al. Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer J Clin Oncol 28 2010 4247 4254
-
(2010)
J Clin Oncol
, vol.28
, pp. 4247-4254
-
-
Chi, K.N.1
Hotte, S.J.2
Yu, E.Y.3
-
63
-
-
84866909021
-
Antitumour activity of docetaxel following treatment with the CYP17A1 inhibitor abiraterone: Clinical evidence for cross-resistance?
-
J. Mezynski, C. Pezaro, and D. Bianchini et al. Antitumour activity of docetaxel following treatment with the CYP17A1 inhibitor abiraterone: clinical evidence for cross-resistance? Ann Oncol 23 2012 2943 2947
-
(2012)
Ann Oncol
, vol.23
, pp. 2943-2947
-
-
Mezynski, J.1
Pezaro, C.2
Bianchini, D.3
-
64
-
-
85009437017
-
Effects on androgen receptor nuclear import by docetaxel, cabazitaxel, abiraterone, and enzalutamide. Potential mechanisms for cross-resistance in castration-resistant prostate cancer (CRPC) [abstract 5064]
-
R.J. van Soest, M.E. van Royen, and E.S. de Morree et al. Effects on androgen receptor nuclear import by docetaxel, cabazitaxel, abiraterone, and enzalutamide. Potential mechanisms for cross-resistance in castration-resistant prostate cancer (CRPC) [abstract 5064] J Clin Oncol 31 Suppl 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Van Soest, R.J.1
Van Royen, M.E.2
De Morree, E.S.3
-
65
-
-
84898742280
-
A randomized phase II study evaluating the optimal sequencing of sipuleucel-T and androgen deprivation therapy (ADT) in biochemically recurrent prostate cancer (BRPC): Immune results [abstract 5016]
-
E.S. Antonarakis, A.S. Kibel, and G. Adams et al. A randomized phase II study evaluating the optimal sequencing of sipuleucel-T and androgen deprivation therapy (ADT) in biochemically recurrent prostate cancer (BRPC): immune results [abstract 5016] J Clin Oncol 31 Suppl 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Antonarakis, E.S.1
Kibel, A.S.2
Adams, G.3
-
66
-
-
84878937422
-
New treatment developments applied to elderly patients with advanced prostate cancer
-
D. Mukherji, C.J. Pezaro, A. Shamseddine, and J.S. De Bono New treatment developments applied to elderly patients with advanced prostate cancer Cancer Treat Rev 39 2013 578 583
-
(2013)
Cancer Treat Rev
, vol.39
, pp. 578-583
-
-
Mukherji, D.1
Pezaro, C.J.2
Shamseddine, A.3
De Bono, J.S.4
-
67
-
-
84874694323
-
Post docetaxel treatment for castration-resistant prostate cancer (CRPC): Does sequencing matter? [abstract e15135]
-
Z.I. Malik, A.H. Montazeri, H. Wong, and C. Eswarvee Post docetaxel treatment for castration-resistant prostate cancer (CRPC): does sequencing matter? [abstract e15135] J Clin Oncol 30 Suppl 2012
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Malik, Z.I.1
Montazeri, A.H.2
Wong, H.3
Eswarvee, C.4
-
68
-
-
84891833046
-
Prognostic factors of survival in patients with metastatic castration resistant prostate cancer (mCRPC) treated with cabazitaxel: Sequencing might matter [abstract 5063]
-
A. Angelergues, D. Maillet, and A. Flechon et al. Prognostic factors of survival in patients with metastatic castration resistant prostate cancer (mCRPC) treated with cabazitaxel: sequencing might matter [abstract 5063] J Clin Oncol 31 Suppl 2013
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Angelergues, A.1
Maillet, D.2
Flechon, A.3
-
69
-
-
84882789820
-
Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100)
-
Y. Loriot, D. Bianchini, and E. Ileana et al. Antitumour activity of abiraterone acetate against metastatic castration-resistant prostate cancer progressing after docetaxel and enzalutamide (MDV3100) Ann Oncol 24 2013 1807 1812
-
(2013)
Ann Oncol
, vol.24
, pp. 1807-1812
-
-
Loriot, Y.1
Bianchini, D.2
Ileana, E.3
-
70
-
-
84882799782
-
Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide
-
K.L. Noonan, S. North, R.L. Bitting, A.J. Armstrong, S.L. Ellard, and K.N. Chi Clinical activity of abiraterone acetate in patients with metastatic castration-resistant prostate cancer progressing after enzalutamide Ann Oncol 24 2013 1802 1807
-
(2013)
Ann Oncol
, vol.24
, pp. 1802-1807
-
-
Noonan, K.L.1
North, S.2
Bitting, R.L.3
Armstrong, A.J.4
Ellard, S.L.5
Chi, K.N.6
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