β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice

British Journal of Pharmacology

Volumn 175, Issue 2, 2018, Pages 320-334

  Varga, Zoltan V ^a   Matyas, Csaba ^a   Erdelyi, Katalin ^a   Cinar, Resat ^a   Nieri, Daniela ^b   Chicca, Andrea ^b   Nemeth, Balazs Tamas ^a   Paloczi, Janos ^a   Lajtos, Tamas ^a   Corey, Lukas ^a   Hasko, Gyorgy ^c   Gao, Bin ^a   Kunos, George ^a   Gertsch, Jürg ^b   Pacher, Pal ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ALANINE AMINOTRANSFERASE; CANNABINOID 2 RECEPTOR; CARYOPHYLLENE; CD11B ANTIGEN; CD163 ANTIGEN; CXCL2 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUCOSE 6 PHOSPHATASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PADGEM PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); TRIACYLGLYCEROL; ALCOHOL; SESQUITERPENE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; FATTY LIVER; GENE EXPRESSION; IN VIVO STUDY; KUPFFER CELL; LIVER PROTECTION; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TREATMENT DURATION; TRIACYLGLYCEROL LEVEL; UPREGULATION; ACETYLATION; ANIMAL; BIOSYNTHESIS; BLOOD; BRAIN; CHEMICALLY INDUCED; DRUG EFFECT; GENETICS; INFLAMMATION; KNOCKOUT MOUSE; LIVER; METABOLISM; TOXIC HEPATITIS;

ACETYLATION; ANIMALS; BRAIN; CHEMICAL AND DRUG INDUCED LIVER INJURY; E-SELECTIN; ETHANOL; FATTY LIVER; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; KUPFFER CELLS; LIVER; MALE; MICE; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; P-SELECTIN; PPAR ALPHA; RECEPTOR, CANNABINOID, CB2; SESQUITERPENES;

EID: 85013436222     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13722     Document Type: Article

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