Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

PLoS ONE

Volumn 12, Issue 2, 2017, Pages

  Hayes, Heather L ^a,c   Peterson, Brett S ^a,b   Haldeman, Jonathan M ^a,b   Newgard, Christopher B ^a,b   Hohmeier, Hans E ^a,b   Stephens, Samuel B ^a,b,d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Zen Bio Inc   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; PUMA PROTEIN; X BOX BINDING PROTEIN 1; X LINKED INHIBITOR OF APOPTOSIS; APAF1 PROTEIN, RAT; GLUCOSE; INHIBITOR OF APOPTOSIS PROTEIN; INSULIN; XIAP PROTEIN, RAT;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA DAMAGE RESPONSE; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; RAT; ANIMAL; CELL CULTURE; CELL LINE; CYTOLOGY; INSULINOMA; METABOLISM; PANCREAS ISLET; PANCREAS TUMOR; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; AUTOPHAGY; CASPASE 3; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; GLUCOSE; INHIBITOR OF APOPTOSIS PROTEINS; INSULIN; INSULINOMA; ISLETS OF LANGERHANS; PANCREATIC NEOPLASMS; RATS;

EID: 85013213291     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0172567     Document Type: Article

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