A human islet cell culture system for high-throughput screening

Journal of Biomolecular Screening

Volumn 17, Issue 4, 2012, Pages 509-518

  Walpita, Deepika ^a   Hasaka, Thomas ^a   Spoonamore, James ^a   Vetere, Amedeo ^a   Takane, Karen K ^b   Fomina Yadlin, Dina ^a,c   Fiaschi Taesch, Nathalie ^b   Shamji, Alykhan ^a   Clemons, Paul A ^a   Stewart, Andrew F ^b   Schreiber, Stuart L ^a,c,d,e   Wagner, Bridget K ^a  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d HARVARD UNIVERSITY   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

assay development; beta cell proliferation; high throughput screening; human islet

Indexed keywords

ADENOVIRUS VECTOR; C PEPTIDE; CYCLIN D1; CYCLIN DEPENDENT KINASE 6; GLUCOSE; KI 67 ANTIGEN; RAPAMYCIN;

ADENOVIRUS; ADOLESCENT; ADULT; ARTICLE; BLADDER CARCINOMA; CANCER CELL CULTURE; CELL PROLIFERATION; CHILD; CONTROLLED STUDY; CULTURE TECHNIQUE; CYTOLOGY; DISSOCIATION; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; INSULIN RELEASE; MICROTITER PLATE ASSAY; MOLECULAR LIBRARY; PANCREAS ISLET CELL; PANCREAS ISLET CELL FUNCTION; PHENOTYPE; PILOT STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

CELL LINE; CELL PROLIFERATION; DRUG EVALUATION, PRECLINICAL; GLUCOSE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; PRIMARY CELL CULTURE; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES;

EID: 84858968454     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111430253     Document Type: Article

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