-
1
-
-
84864740280
-
Pulmonary fibrosis: Patterns and perpetrators
-
Noble PW, Barkauskas CE, Jiang D. Pulmonary fibrosis: patterns and perpetrators. J Clin Invest 2012;122:2756-2762.
-
(2012)
J Clin Invest
, vol.122
, pp. 2756-2762
-
-
Noble, P.W.1
Barkauskas, C.E.2
Jiang, D.3
-
3
-
-
84901789076
-
Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis
-
Barkauskas CE, Noble PW. Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis. Am J Physiol Cell Physiol 2014;306:C987-C996.
-
(2014)
Am J Physiol Cell Physiol
, vol.306
, pp. C987-C996
-
-
Barkauskas, C.E.1
Noble, P.W.2
-
5
-
-
79551683487
-
Cellular senescence: Putting the paradoxes in perspective
-
Campisi J. Cellular senescence: putting the paradoxes in perspective. Curr Opin Genet Dev 2011;21:107-112.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 107-112
-
-
Campisi, J.1
-
7
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961;25:585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
8
-
-
84901288438
-
The role of senescent cells in ageing
-
van Deursen JM. The role of senescent cells in ageing. Nature 2014;509: 439-446.
-
(2014)
Nature
, vol.509
, pp. 439-446
-
-
Van Deursen, J.M.1
-
9
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky V, Yon M, Dickins RA, Hearn S, Simon J, Miething C, Yee H, Zender L, Lowe SW. Senescence of activated stellate cells limits liver fibrosis. Cell 2008;134:657-667.
-
(2008)
Cell
, vol.134
, pp. 657-667
-
-
Krizhanovsky, V.1
Yon, M.2
Dickins, R.A.3
Hearn, S.4
Simon, J.5
Miething, C.6
Yee, H.7
Zender, L.8
Lowe, S.W.9
-
10
-
-
77954243065
-
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
-
Jun JI, Lau LF. The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol 2010;12:676-685.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 676-685
-
-
Jun, J.I.1
Lau, L.F.2
-
11
-
-
84899103689
-
Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance
-
Hecker L, Logsdon NJ, Kurundkar D, Kurundkar A, Bernard K, Hock T, Meldrum E, Sanders YY, Thannickal VJ. Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance. Sci Transl Med 2014;6:231ra47.
-
(2014)
Sci Transl Med
, vol.6
, pp. 231ra47
-
-
Hecker, L.1
Logsdon, N.J.2
Kurundkar, D.3
Kurundkar, A.4
Bernard, K.5
Hock, T.6
Meldrum, E.7
Sanders, Y.Y.8
Thannickal, V.J.9
-
12
-
-
84901733241
-
Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction
-
Zhu F, Li Y, Zhang J, Piao C, Liu T, Li HH, Du J. Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction. PLoS One 2013;8:e74535.
-
(2013)
PLoS One
, vol.8
, pp. e74535
-
-
Zhu, F.1
Li, Y.2
Zhang, J.3
Piao, C.4
Liu, T.5
Li, H.H.6
Du, J.7
-
13
-
-
84863799096
-
Caveolin-1 deficiency protects from pulmonary fibrosis by modulating epithelial cell senescence in mice
-
Shivshankar P, Brampton C, Miyasato S, Kasper M, Thannickal VJ, Le Saux CJ. Caveolin-1 deficiency protects from pulmonary fibrosis by modulating epithelial cell senescence in mice. Am J Respir Cell Mol Biol 2012;47:28-36.
-
(2012)
Am J Respir Cell Mol, Biol
, vol.47
, pp. 28-36
-
-
Shivshankar, P.1
Brampton, C.2
Miyasato, S.3
Kasper, M.4
Thannickal, V.J.5
Le, S.C.J.6
-
14
-
-
79955047394
-
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGFb-induced senescence of human bronchial epithelial cells
-
Minagawa S, Araya J, Numata T, Nojiri S, Hara H, Yumino Y, Kawaishi M, Odaka M, Morikawa T, Nishimura SL, et al. Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGFb- induced senescence of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 2011;300:L391-L401.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L391-L401
-
-
Minagawa, S.1
Araya, J.2
Numata, T.3
Nojiri, S.4
Hara, H.5
Yumino, Y.6
Kawaishi, M.7
Odaka, M.8
Morikawa, T.9
Nishimura, S.L.10
-
15
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell 2012;148:1172-1187.
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
16
-
-
77955373730
-
MIR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
-
Liu G, Friggeri A, Yang Y, Milosevic J, Ding Q, Thannickal VJ, Kaminski N, Abraham E. miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis. J Exp Med 2010;207:1589- 1597.
-
(2010)
J Exp Med
, vol.207
, pp. 1589-1597
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
Milosevic, J.4
Ding, Q.5
Thannickal, V.J.6
Kaminski, N.7
Abraham, E.8
-
17
-
-
84878758490
-
MIR-145 regulates myofibroblast differentiation and lung fibrosis
-
Yang S, Cui H, Xie N, Icyuz M, Banerjee S, Antony VB, Abraham E, Thannickal VJ, Liu G. miR-145 regulates myofibroblast differentiation and lung fibrosis. FASEB J 2013;27:2382-2391.
-
(2013)
FASEB J
, vol.27
, pp. 2382-2391
-
-
Yang, S.1
Cui, H.2
Xie, N.3
Icyuz, M.4
Banerjee, S.5
Antony, V.B.6
Abraham, E.7
Thannickal, V.J.8
Liu, G.9
-
18
-
-
84856044224
-
MicroRNAs in lung diseases
-
Pagdin T, Lavender P. MicroRNAs in lung diseases. Thorax 2012;67: 183-184.
-
(2012)
Thorax
, vol.67
, pp. 183-184
-
-
Pagdin, T.1
Lavender, P.2
-
19
-
-
80051655553
-
MIR-29 is a major regulator of genes associated with pulmonary fibrosis
-
Cushing L, Kuang PP, Qian J, Shao F, Wu J, Little F, Thannickal VJ, Cardoso WV, LüJ. miR-29 is a major regulator of genes associated with pulmonary fibrosis. Am J Respir Cell Mol Biol 2011;45:287-294.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 287-294
-
-
Cushing, L.1
Kuang, P.P.2
Qian, J.3
Shao, F.4
Wu, J.5
Little, F.6
Thannickal, V.J.7
Cardoso, W.V.8
LüJ9
-
20
-
-
84856006423
-
Participation of MIR-200 in pulmonary fibrosis
-
Yang S, Banerjee S, de Freitas A, Sanders YY, Ding Q, Matalon S, Thannickal VJ, Abraham E, Liu G. Participation of miR-200 in pulmonary fibrosis. Am J Pathol 2012;180:484-493.
-
(2012)
Am J Pathol
, vol.180
, pp. 484-493
-
-
Yang, S.1
Banerjee, S.2
De Freitas, A.3
Sanders, Y.Y.4
Ding, Q.5
Matalon, S.6
Thannickal, V.J.7
Abraham, E.8
Liu, G.9
-
21
-
-
84964296861
-
MicroRNA regulatory networks in idiopathic pulmonary fibrosis
-
Pandit KV, Milosevic J. MicroRNA regulatory networks in idiopathic pulmonary fibrosis. Biochem Cell Biol 2015;93:129-137.
-
(2015)
Biochem Cell Biol
, vol.93
, pp. 129-137
-
-
Pandit, K.V.1
Milosevic, J.2
-
22
-
-
84943279279
-
MIR-142-5p and MIR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
-
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, Chen J, Liao JY, Cui X, Zeng Y, et al. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nat Commun 2015;6:8523.
-
(2015)
Nat Commun
, vol.6
, pp. 8523
-
-
Su, S.1
Zhao, Q.2
He, C.3
Huang, D.4
Liu, J.5
Chen, F.6
Chen, J.7
Liao, J.Y.8
Cui, X.9
Zeng, Y.10
-
23
-
-
85026596008
-
MIR-34a regulates senescence of lung fibroblasts and lung fibrosis [abstract]
-
Cui H, Xie N, Tan Z, Liu RM, Ding Q, Zhou Y, Andrade JA, Luckhardt TR, Antony VB, Thannickal VJ, et al. miR-34a regulates senescence of lung fibroblasts and lung fibrosis [abstract]. Am J Respir Crit Care Med 2015;191:A5317.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. A5317
-
-
Cui, H.1
Xie, N.2
Tan, Z.3
Liu, R.M.4
Ding, Q.5
Zhou, Y.6
Andrade, J.A.7
Luckhardt, T.R.8
Antony, V.B.9
Thannickal, V.J.10
-
24
-
-
65249088418
-
WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
-
Königshoff M, Kramer M, Balsara N, Wilhelm J, Amarie OV, Jahn A, Rose F, Fink L, Seeger W, Schaefer L, et al. WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 2009;119:772-787.
-
(2009)
J Clin Invest
, vol.119
, pp. 772-787
-
-
Königshoff, M.1
Kramer, M.2
Balsara, N.3
Wilhelm, J.4
Amarie, O.V.5
Jahn, A.6
Rose, F.7
Fink, L.8
Seeger, W.9
Schaefer, L.10
-
25
-
-
84988850898
-
MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation
-
Cui H, Banerjee S, Xie N, Ge J, Liu RM, Matalon S, Thannickal VJ, Liu G. MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation. Am J Respir Cell Mol Biol 2016; 54:843-852.
-
(2016)
Am J Respir Cell Mol Biol
, vol.54
, pp. 843-852
-
-
Cui, H.1
Banerjee, S.2
Xie, N.3
Ge, J.4
Liu, R.M.5
Matalon, S.6
Thannickal, V.J.7
Liu, G.8
-
26
-
-
46749110737
-
Interleukin-1 receptor-Associated kinase (IRAK)-1-mediated NF-kB activation requires cytosolic and nuclear activity
-
Liu G, Park YJ, Abraham E. Interleukin-1 receptor-Associated kinase (IRAK)-1-mediated NF-kB activation requires cytosolic and nuclear activity. FASEB J 2008;22:2285-2296.
-
(2008)
FASEB J
, vol.22
, pp. 2285-2296
-
-
Liu, G.1
Park, Y.J.2
Abraham, E.3
-
27
-
-
34848868157
-
Tumor-suppressive MIR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
-
Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci USA 2007;104:15472-15477.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15472-15477
-
-
Tazawa, H.1
Tsuchiya, N.2
Izumiya, M.3
Nakagama, H.4
-
28
-
-
44849091255
-
p53 to both down-regulate inhibitor of growth 2 and upregulate MIR-34a, MIR-34b, and MIR-34c expression, and induce senescence
-
p53 to both down-regulate inhibitor of growth 2 and upregulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. Cancer Res 2008;68:3193-3203.
-
(2008)
Cancer Res
, vol.68
, pp. 3193-3203
-
-
Kumamoto, K.1
Spillare, E.A.2
Fujita, K.3
Horikawa, I.4
Yamashita, T.5
Appella, E.6
Nagashima, M.7
Takenoshita, S.8
Yokota, J.9
Harris, C.C.10
-
29
-
-
74249124132
-
p53-independent upregulation of MIR-34a during oncogene-induced senescence represses MYC
-
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC. Cell Death Differ 2010;17:236-245.
-
(2010)
Cell Death Differ
, vol.17
, pp. 236-245
-
-
Christoffersen, N.R.1
Shalgi, R.2
Frankel, L.B.3
Leucci, E.4
Lees, M.5
Klausen, M.6
Pilpel, Y.7
Nielsen, F.C.8
Oren, M.9
Lund, A.H.10
-
30
-
-
84949555897
-
Cellular senescence in aging and age-related disease: From mechanisms to therapy
-
Childs BG, Durik M, Baker DJ, van Deursen JM. Cellular senescence in aging and age-related disease: From mechanisms to therapy. Nat Med 2015;21:1424-1435.
-
(2015)
Nat Med
, vol.21
, pp. 1424-1435
-
-
Childs, B.G.1
Durik, M.2
Baker, D.J.3
Van Deursen, J.M.4
-
31
-
-
84865808428
-
The impact of TGF-b on lung fibrosis: From targeting to biomarkers
-
Fernandez IE, Eickelberg O. The impact of TGF-b on lung fibrosis: From targeting to biomarkers. Proc Am Thorac Soc 2012;9:111-116.
-
(2012)
Proc Am Thorac Soc
, vol.9
, pp. 111-116
-
-
Fernandez, I.E.1
Eickelberg, O.2
-
32
-
-
84962622170
-
Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis
-
Li Y, Liang J, Yang T, Monterrosa Mena J, Huan C, Xie T, Kurkciyan A, Liu N, Jiang D, Noble PW. Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. Matrix Biol 2016;55: 35-48.
-
(2016)
Matrix Biol
, vol.55
, pp. 35-48
-
-
Li, Y.1
Liang, J.2
Yang, T.3
Monterrosa, M.J.4
Huan, C.5
Xie, T.6
Kurkciyan, A.7
Liu, N.8
Jiang, D.9
Noble, P.W.10
-
33
-
-
0032485213
-
Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
-
Robles SJ, Adami GR. Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts. Oncogene 1998;16:1113-1123.
-
(1998)
Oncogene
, vol.16
, pp. 1113-1123
-
-
Robles, S.J.1
Adami, G.R.2
-
34
-
-
84874609382
-
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
-
Zhou Y, Huang X, Hecker L, Kurundkar D, Kurundkar A, Liu H, Jin TH, Desai L, Bernard K, Thannickal VJ. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest 2013;123:1096-1108.
-
(2013)
J Clin Invest
, vol.123
, pp. 1096-1108
-
-
Zhou, Y.1
Huang, X.2
Hecker, L.3
Kurundkar, D.4
Kurundkar, A.5
Liu, H.6
Jin, T.H.7
Desai, L.8
Bernard, K.9
Thannickal, V.J.10
-
35
-
-
33644692330
-
Cellular senescence in aging primates
-
Herbig U, Ferreira M, Condel L, Carey D, Sedivy JM. Cellular senescence in aging primates. Science 2006;311:1257.
-
(2006)
Science
, vol.311
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
36
-
-
84962528127
-
Cellular senescence as the causal nexus of aging
-
Bhatia-Dey N, Kanherkar RR, Stair SE, Makarev EO, Csoka AB. Cellular senescence as the causal nexus of aging. Front Genet 2016; 7:13.
-
(2016)
Front Genet
, vol.7
, pp. 13
-
-
Bhatia-Dey, N.1
Kanherkar, R.R.2
Stair, S.E.3
Makarev, E.O.4
Csoka, A.B.5
-
37
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F. Cellular senescence: When bad things happen to good cells. Nat Rev Mol Cell Biol 2007;8:729-740.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
Di D'Adda, F.F.2
-
38
-
-
34447543913
-
Cellular senescence in cancer and aging
-
Collado M, Blasco MA, Serrano M. Cellular senescence in cancer and aging. Cell 2007;130:223-233.
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Blasco, M.A.2
Serrano, M.3
-
39
-
-
84904702784
-
Cellular senescence: From physiology to pathology
-
Muñoz-Esṕin D, Serrano M. Cellular senescence: From physiology to pathology. Nat Rev Mol Cell Biol 2014;15:482-496.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 482-496
-
-
Muñoz-Esṕin, D.1
Serrano, M.2
-
40
-
-
79952563157
-
Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases
-
Pitiyage GN, Slijepcevic P, Gabrani A, Chianea YG, Lim KP, Prime SS, Tilakaratne WM, Fortune F, Parkinson EK. Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases. J Pathol 2011;223:604-617.
-
(2011)
J Pathol
, vol.223
, pp. 604-617
-
-
Pitiyage, G.N.1
Slijepcevic, P.2
Gabrani, A.3
Chianea, Y.G.4
Lim, K.P.5
Prime, S.S.6
Tilakaratne, W.M.7
Fortune, F.8
Parkinson, E.K.9
-
42
-
-
84874603171
-
Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
-
Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities. J Clin Invest 2013;123:966-972.
-
(2013)
J Clin Invest
, vol.123
, pp. 966-972
-
-
Tchkonia, T.1
Zhu, Y.2
Van Deursen, J.3
Campisi, J.4
Kirkland, J.L.5
-
43
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature 2013;496:445-455.
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
44
-
-
84880062414
-
Accelerated development of pulmonary fibrosis via Cu, Zn-superoxide dismutase-induced alternative activation of macrophages
-
He C, Ryan AJ, Murthy S, Carter AB. Accelerated development of pulmonary fibrosis via Cu, Zn-superoxide dismutase-induced alternative activation of macrophages. J Biol Chem 2013;288: 20745-20757.
-
(2013)
J Biol Chem
, vol.288
, pp. 20745-20757
-
-
He, C.1
Ryan, A.J.2
Murthy, S.3
Carter, A.B.4
-
45
-
-
84960392538
-
Macrophage Akt1 kinase-mediated mitophagy modulates apoptosis resistance and pulmonary fibrosis
-
Larson-Casey JL, Deshane JS, Ryan AJ, Thannickal VJ, Carter AB. Macrophage Akt1 kinase-mediated mitophagy modulates apoptosis resistance and pulmonary fibrosis. Immunity 2016;44:582-596.
-
(2016)
Immunity
, vol.44
, pp. 582-596
-
-
Larson-Casey, J.L.1
Deshane, J.S.2
Ryan, A.J.3
Thannickal, V.J.4
Carter, A.B.5
|