Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20745-20757

  He, Chao ^a   Ryan, Alan J ^a   Murthy, Shubha ^a   Carter, A Brent ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c Veterans Administration   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CU ,ZN SUPEROXIDE DISMUTASE; DIFFERENTIATION PROCESS; MACROPHAGE PHENOTYPES; PULMONARY FIBROSIS; THERAPEUTIC TARGETS; TISSUE REMODELING; TRANSCRIPTIONAL LEVELS; TUMOR PROGRESSIONS;

AMINO ACIDS; OXYGEN; POLARIZATION; REPAIR; TISSUE; TRANSCRIPTION; ZINC;

MACROPHAGES;

COPPER ZINC SUPEROXIDE DISMUTASE; CYSTEINE; HYDROGEN PEROXIDE; STAT6 PROTEIN;

ADULT; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG FIBROSIS; MACROPHAGE ACTIVATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; TISSUE INJURY; TUMOR GROWTH;

HYDROGEN PEROXIDE; MACROPHAGE PHENOTYPE; MITOCHONDRIA; OXIDATIVE STRESS; PULMONARY FIBROSIS; STAT6; SUPEROXIDE DISMUTASE (SOD);

ADOLESCENT; ADULT; ANIMALS; CELL LINE; CELL POLARITY; CYTOKINES; DISEASE PROGRESSION; GENE EXPRESSION; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MITOCHONDRIA; PULMONARY FIBROSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; TH2 CELLS; YOUNG ADULT;

EID: 84880062414     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.410720     Document Type: Article

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