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Volumn 44, Issue 5, 2018, Pages 483-492

Mechanisms of Cellular Activation in the Antiphospholipid Syndrome

Author keywords

annexins; antiphospholipid antibodies; low density lipoprotein receptor related protein 8; NADPH oxidase; signal transduction; toll like receptors

Indexed keywords

APOLIPOPROTEIN E RECEPTOR 2; COMPLEMENT; LIPOCORTIN 2; LIPOCORTIN 5; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 8; MAMMALIAN TARGET OF RAPAMYCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

EID: 85011816623     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0036-1597290     Document Type: Article
Times cited : (18)

References (100)
  • 1
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: A model for autoimmune fetal loss
    • Branch D. W. Dudley D. J. Mitchell M. D., et al. Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: a model for autoimmune fetal loss. Am J Obstet Gynecol: 1990; 163 (1, Pt 1): 210 216
    • (1990) Am J Obstet Gynecol , vol.163 , Issue.1 , pp. 210-216
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3
  • 2
    • 0026322836 scopus 로고
    • Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies
    • Blank M. Cohen J. Toder V. Shoenfeld Y. Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci U S A: 1991; 88 08 3069 3073
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.8 , pp. 3069-3073
    • Blank, M.1    Cohen, J.2    Toder, V.3    Shoenfeld, Y.4
  • 3
    • 0028173807 scopus 로고
    • Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice
    • Pierangeli S. S. Barker J. H. Stikovac D., et al. Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice. Thromb Haemost: 1994; 71 05 670 674
    • (1994) Thromb Haemost , vol.71 , Issue.5 , pp. 670-674
    • Pierangeli, S.S.1    Barker, J.H.2    Stikovac, D.3
  • 4
    • 84859420078 scopus 로고    scopus 로고
    • Examining how antiphospholipid antibodies activate intracellular signaling pathways: A systematic review
    • Poulton K. Rahman A. Giles I. Examining how antiphospholipid antibodies activate intracellular signaling pathways: a systematic review. Semin Arthritis Rheum: 2012; 41 05 720 736
    • (2012) Semin Arthritis Rheum , vol.41 , Issue.5 , pp. 720-736
    • Poulton, K.1    Rahman, A.2    Giles, I.3
  • 5
    • 79953083750 scopus 로고    scopus 로고
    • 2-Glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model
    • 2 -Glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model. Blood: 2011; 117 12 3453 3459
    • (2011) Blood , vol.117 , Issue.12 , pp. 3453-3459
    • Arad, A.1    Proulle, V.2    Furie, R.A.3    Furie, B.C.4    Furie, B.5
  • 6
    • 84926465767 scopus 로고    scopus 로고
    • Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain i of β2-glycoprotein i in a mouse model of anti-phospholipid antibody-induced thrombosis
    • Pericleous C. Ruiz-Limón P. Romay-Penabad Z., et al. Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis. Rheumatology (Oxford): 2015; 54 04 722 727
    • (2015) Rheumatology (Oxford) , vol.54 , Issue.4 , pp. 722-727
    • Pericleous, C.1    Ruiz-Limón, P.2    Romay-Penabad, Z.3
  • 7
    • 0027474773 scopus 로고
    • Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis
    • Branch D. W. Rodgers G. M. Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: a possible mechanism of thrombosis. Am J Obstet Gynecol: 1993; 168 (1, Pt 1): 206 210
    • (1993) Am J Obstet Gynecol , vol.168 , Issue.1 , pp. 206-210
    • Branch, D.W.1    Rodgers, G.M.2
  • 8
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • Kornberg A. Blank M. Kaufman S. Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol: 1994; 153 03 1328 1332
    • (1994) J Immunol , vol.153 , Issue.3 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 9
    • 0031876263 scopus 로고    scopus 로고
    • Effects of human monoclonal anticardiolipin antibodies on platelet function and on tissue factor expression on monocytes
    • Reverter J. C. Tàssies D. Font J., et al. Effects of human monoclonal anticardiolipin antibodies on platelet function and on tissue factor expression on monocytes. Arthritis Rheum: 1998; 41 08 1420 1427
    • (1998) Arthritis Rheum , vol.41 , Issue.8 , pp. 1420-1427
    • Reverter, J.C.1    Tàssies, D.2    Font, J.3
  • 10
    • 84891634809 scopus 로고    scopus 로고
    • The role of TLR4 in pathophysiology of antiphospholipid syndrome-associated thrombosis and pregnancy morbidity
    • Xie H. Sheng L. Zhou H. Yan J. The role of TLR4 in pathophysiology of antiphospholipid syndrome-associated thrombosis and pregnancy morbidity. Br J Haematol: 2014; 164 02 165 176
    • (2014) Br J Haematol , vol.164 , Issue.2 , pp. 165-176
    • Xie, H.1    Sheng, L.2    Zhou, H.3    Yan, J.4
  • 11
    • 14944367961 scopus 로고    scopus 로고
    • Annexin A2 mediates endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein i antibodies
    • Zhang J. McCrae K. R. Annexin A2 mediates endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein I antibodies. Blood: 2005; 105 05 1964 1969
    • (2005) Blood , vol.105 , Issue.5 , pp. 1964-1969
    • Zhang, J.1    McCrae, K.R.2
  • 12
    • 70049084409 scopus 로고    scopus 로고
    • In vitro effects of antiphospholipid syndrome-IgG fractions and human monoclonal antiphospholipid IgG antibody on human umbilical vein endothelial cells and monocytes
    • Clemens N. Frauenknecht K. Katzav A. Sommer C. von Landenberg P. In vitro effects of antiphospholipid syndrome-IgG fractions and human monoclonal antiphospholipid IgG antibody on human umbilical vein endothelial cells and monocytes. Ann N Y Acad Sci: 2009; 1173 805 813
    • (2009) Ann N y Acad Sci , vol.1173 , pp. 805-813
    • Clemens, N.1    Frauenknecht, K.2    Katzav, A.3    Sommer, C.4    Von Landenberg, P.5
  • 13
    • 84874767596 scopus 로고    scopus 로고
    • Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells. Lessons from the antiphospholipid syndrome
    • Prinz N. Clemens N. Canisius A. Lackner K. J. Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells. Lessons from the antiphospholipid syndrome. Thromb Haemost: 2013; 109 03 525 531
    • (2013) Thromb Haemost , vol.109 , Issue.3 , pp. 525-531
    • Prinz, N.1    Clemens, N.2    Canisius, A.3    Lackner, K.J.4
  • 14
    • 67650651969 scopus 로고    scopus 로고
    • Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway
    • Mulla M. J. Brosens J. J. Chamley L. W., et al. Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway. Am J Reprod Immunol: 2009; 62 02 96 111
    • (2009) Am J Reprod Immunol , vol.62 , Issue.2 , pp. 96-111
    • Mulla, M.J.1    Brosens, J.J.2    Chamley, L.W.3
  • 15
    • 7244242660 scopus 로고    scopus 로고
    • Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: A pathway to targeted therapies
    • Pierangeli S. S. Vega-Ostertag M. Harris E. N. Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. Thromb Res: 2004; 114 05/06 467 476
    • (2004) Thromb Res , vol.114 , Issue.5-6 , pp. 467-476
    • Pierangeli, S.S.1    Vega-Ostertag, M.2    Harris, E.N.3
  • 16
    • 84922395739 scopus 로고    scopus 로고
    • IgG accumulates in inhibitory hippocampal neurons of experimental antiphospholipid syndrome
    • Katzav A. Menachem A. Maggio N. Pollak L. Pick C. G. Chapman J. IgG accumulates in inhibitory hippocampal neurons of experimental antiphospholipid syndrome. J Autoimmun: 2014; 55 86 93
    • (2014) J Autoimmun , vol.55 , pp. 86-93
    • Katzav, A.1    Menachem, A.2    Maggio, N.3    Pollak, L.4    Pick, C.G.5    Chapman, J.6
  • 17
    • 84864485999 scopus 로고    scopus 로고
    • A role for Toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndrome
    • Gladigau G. Haselmayer P. Scharrer I., et al. A role for Toll-like receptor mediated signals in neutrophils in the pathogenesis of the anti-phospholipid syndrome. PLoS One: 2012; 7 07 e42176
    • (2012) PLoS One , vol.7 , Issue.7 , pp. e42176
    • Gladigau, G.1    Haselmayer, P.2    Scharrer, I.3
  • 18
    • 0026763468 scopus 로고
    • Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum
    • Sun K. H. Liu W. T. Tsai C. Y. Liao T. S. Lin W. M. Yu C. L. Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum. Ann Rheum Dis: 1992; 51 06 707 712
    • (1992) Ann Rheum Dis , vol.51 , Issue.6 , pp. 707-712
    • Sun, K.H.1    Liu, W.T.2    Tsai, C.Y.3    Liao, T.S.4    Lin, W.M.5    Yu, C.L.6
  • 19
    • 80052140024 scopus 로고    scopus 로고
    • Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells
    • Prinz N. Clemens N. Strand D., et al. Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells. Blood: 2011; 118 08 2322 2332
    • (2011) Blood , vol.118 , Issue.8 , pp. 2322-2332
    • Prinz, N.1    Clemens, N.2    Strand, D.3
  • 20
    • 10144232761 scopus 로고    scopus 로고
    • Thrombogenic properties of murine anti-cardiolipin antibodies induced by beta 2 glycoprotein 1 and human immunoglobulin G antiphospholipid antibodies
    • Pierangeli S. S. Liu S. W. Anderson G. Barker J. H. Harris E. N. Thrombogenic properties of murine anti-cardiolipin antibodies induced by beta 2 glycoprotein 1 and human immunoglobulin G antiphospholipid antibodies. Circulation: 1996; 94 07 1746 1751
    • (1996) Circulation , vol.94 , Issue.7 , pp. 1746-1751
    • Pierangeli, S.S.1    Liu, S.W.2    Anderson, G.3    Barker, J.H.4    Harris, E.N.5
  • 21
    • 0036083696 scopus 로고    scopus 로고
    • Annexins: From structure to function
    • Gerke V. Moss S. E. Annexins: from structure to function. Physiol Rev: 2002; 82 02 331 371
    • (2002) Physiol Rev , vol.82 , Issue.2 , pp. 331-371
    • Gerke, V.1    Moss, S.E.2
  • 22
    • 50349088997 scopus 로고    scopus 로고
    • Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11
    • He K. L. Deora A. B. Xiong H., et al. Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11. J Biol Chem: 2008; 283 28 19192 19200
    • (2008) J Biol Chem , vol.283 , Issue.28 , pp. 19192-19200
    • He, K.L.1    Deora, A.B.2    Xiong, H.3
  • 23
    • 53949091796 scopus 로고    scopus 로고
    • Annexin A2 regulates the levels of plasmin, S100A10 and Fascin in L5178Y cells
    • Hou Y. Yang L. Mou M., et al. Annexin A2 regulates the levels of plasmin, S100A10 and Fascin in L5178Y cells. Cancer Invest: 2008; 26 08 809 815
    • (2008) Cancer Invest , vol.26 , Issue.8 , pp. 809-815
    • Hou, Y.1    Yang, L.2    Mou, M.3
  • 24
    • 0034605044 scopus 로고    scopus 로고
    • Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains
    • Babiychuk E. B. Draeger A. Annexins in cell membrane dynamics. Ca(2+)-regulated association of lipid microdomains. J Cell Biol: 2000; 150 05 1113 1124
    • (2000) J Cell Biol , vol.150 , Issue.5 , pp. 1113-1124
    • Babiychuk, E.B.1    Draeger, A.2
  • 25
    • 0033598190 scopus 로고    scopus 로고
    • Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton
    • Oliferenko S. Paiha K. Harder T., et al. Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton. J Cell Biol: 1999; 146 04 843 854
    • (1999) J Cell Biol , vol.146 , Issue.4 , pp. 843-854
    • Oliferenko, S.1    Paiha, K.2    Harder, T.3
  • 26
    • 84875514370 scopus 로고    scopus 로고
    • Annexin A2 heterotetramer: Structure and function
    • Bharadwaj A. Bydoun M. Holloway R. Waisman D. Annexin A2 heterotetramer: structure and function. Int J Mol Sci: 2013; 14 03 6259 6305
    • (2013) Int J Mol Sci , vol.14 , Issue.3 , pp. 6259-6305
    • Bharadwaj, A.1    Bydoun, M.2    Holloway, R.3    Waisman, D.4
  • 27
    • 0034685886 scopus 로고    scopus 로고
    • High affinity binding of beta 2-glycoprotein i to human endothelial cells is mediated by annexin II
    • Ma K. Simantov R. Zhang J. C. Silverstein R. Hajjar K. A. McCrae K. R. High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem: 2000; 275 20 15541 15548
    • (2000) J Biol Chem , vol.275 , Issue.20 , pp. 15541-15548
    • Ma, K.1    Simantov, R.2    Zhang, J.C.3    Silverstein, R.4    Hajjar, K.A.5    McCrae, K.R.6
  • 28
    • 34547914850 scopus 로고    scopus 로고
    • Involvement of annexin A2 in anti-beta2GPI/beta2GPI-induced tissue factor expression on monocytes
    • Zhou H. Ling S. Yu Y. Wang T. Hu H. Involvement of annexin A2 in anti-beta2GPI/beta2GPI-induced tissue factor expression on monocytes. Cell Res: 2007; 17 08 737 739
    • (2007) Cell Res , vol.17 , Issue.8 , pp. 737-739
    • Zhou, H.1    Ling, S.2    Yu, Y.3    Wang, T.4    Hu, H.5
  • 29
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z. Montiel-Manzano M. G. Shilagard T., et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood: 2009; 114 14 3074 3083
    • (2009) Blood , vol.114 , Issue.14 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 31
    • 39549099464 scopus 로고    scopus 로고
    • Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome
    • Urbanus R. T. Derksen R. H. de Groot P. G. Current insight into diagnostics and pathophysiology of the antiphospolipid syndrome. Blood Rev: 2008; 22 02 93 105
    • (2008) Blood Rev , vol.22 , Issue.2 , pp. 93-105
    • Urbanus, R.T.1    Derksen, R.H.2    De Groot, P.G.3
  • 32
    • 59649101650 scopus 로고    scopus 로고
    • Annexin A2: Biology and relevance to the antiphospholipid syndrome
    • Cockrell E. Espinola R. G. McCrae K. R. Annexin A2: biology and relevance to the antiphospholipid syndrome. Lupus: 2008; 17 10 943 951
    • (2008) Lupus , vol.17 , Issue.10 , pp. 943-951
    • Cockrell, E.1    Espinola, R.G.2    McCrae, K.R.3
  • 33
    • 84862909113 scopus 로고    scopus 로고
    • A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein i antibodies
    • Allen K. L. Fonseca F. V. Betapudi V. Willard B. Zhang J. McCrae K. R. A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies. Blood: 2012; 119 03 884 893
    • (2012) Blood , vol.119 , Issue.3 , pp. 884-893
    • Allen, K.L.1    Fonseca, F.V.2    Betapudi, V.3    Willard, B.4    Zhang, J.5    McCrae, K.R.6
  • 34
    • 85019050503 scopus 로고    scopus 로고
    • Extracellular vesicles in the antiphospholipid syndrome
    • Chaturvedi S. Alluri R. McCrae K. R. Extracellular vesicles in the antiphospholipid syndrome. Semin Thromb Hemost: 2018; 44 05 493 504
    • (2018) Semin Thromb Hemost , vol.44 , Issue.5 , pp. 493-504
    • Chaturvedi, S.1    Alluri, R.2    McCrae, K.R.3
  • 36
    • 0023729210 scopus 로고
    • Placental anticoagulant proteins: Isolation and comparative characterization four members of the lipocortin family
    • Tait J. F. Sakata M. McMullen B. A., et al. Placental anticoagulant proteins: isolation and comparative characterization four members of the lipocortin family. Biochemistry: 1988; 27 17 6268 6276
    • (1988) Biochemistry , vol.27 , Issue.17 , pp. 6268-6276
    • Tait, J.F.1    Sakata, M.2    McMullen, B.A.3
  • 37
    • 0026029142 scopus 로고
    • Sub-domain structure of lipid-bound annexin-V resolved by electron image analysis
    • Mosser G. Ravanat C. Freyssinet J. M. Brisson A. Sub-domain structure of lipid-bound annexin-V resolved by electron image analysis. J Mol Biol: 1991; 217 02 241 245
    • (1991) J Mol Biol , vol.217 , Issue.2 , pp. 241-245
    • Mosser, G.1    Ravanat, C.2    Freyssinet, J.M.3    Brisson, A.4
  • 38
    • 0028245914 scopus 로고
    • Three-dimensional structure of membrane-bound annexin V. A correlative electron microscopy-X-ray crystallography study
    • Voges D. Berendes R. Burger A. Demange P. Baumeister W. Huber R. Three-dimensional structure of membrane-bound annexin V. A correlative electron microscopy-X-ray crystallography study. J Mol Biol: 1994; 238 02 199 213
    • (1994) J Mol Biol , vol.238 , Issue.2 , pp. 199-213
    • Voges, D.1    Berendes, R.2    Burger, A.3    Demange, P.4    Baumeister, W.5    Huber, R.6
  • 39
    • 0031880366 scopus 로고    scopus 로고
    • Growth of protein 2-D crystals on supported planar lipid bilayers imaged in situ by AFM
    • Reviakine I. Bergsma-Schutter W. Brisson A. Growth of protein 2-D crystals on supported planar lipid bilayers imaged in situ by AFM. J Struct Biol: 1998; 121 03 356 361
    • (1998) J Struct Biol , vol.121 , Issue.3 , pp. 356-361
    • Reviakine, I.1    Bergsma-Schutter, W.2    Brisson, A.3
  • 40
    • 0026744185 scopus 로고
    • Clustering of lipid-bound annexin v may explain its anticoagulant effect
    • Andree H. A. Stuart M. C. Hermens W. T., et al. Clustering of lipid-bound annexin V may explain its anticoagulant effect. J Biol Chem: 1992; 267 25 17907 17912
    • (1992) J Biol Chem , vol.267 , Issue.25 , pp. 17907-17912
    • Andree, H.A.1    Stuart, M.C.2    Hermens, W.T.3
  • 41
    • 0030789659 scopus 로고    scopus 로고
    • Pregnancy loss in the antiphospholipid-antibody syndrome - A possible thrombogenic mechanism
    • Rand J. H. Wu X. X. Andree H. A., et al. Pregnancy loss in the antiphospholipid-antibody syndrome - a possible thrombogenic mechanism. N Engl J Med: 1997; 337 03 154 160
    • (1997) N Engl J Med , vol.337 , Issue.3 , pp. 154-160
    • Rand, J.H.1    Wu, X.X.2    Andree, H.A.3
  • 42
    • 0030692601 scopus 로고    scopus 로고
    • Antiphosphatidylserine antibody removes annexin-V and facilitates the binding of prothrombin at the surface of a choriocarcinoma model of trophoblast differentiation
    • Vogt E. Ng A. K. Rote N. S. Antiphosphatidylserine antibody removes annexin-V and facilitates the binding of prothrombin at the surface of a choriocarcinoma model of trophoblast differentiation. Am J Obstet Gynecol: 1997; 177 04 964 972
    • (1997) Am J Obstet Gynecol , vol.177 , Issue.4 , pp. 964-972
    • Vogt, E.1    Ng, A.K.2    Rote, N.S.3
  • 43
    • 11144229526 scopus 로고    scopus 로고
    • Decreased binding of annexin v to endothelial cells: A potential mechanism in atherothrombosis of patients with systemic lupus erythematosus
    • Cederholm A. Svenungsson E. Jensen-Urstad K., et al. Decreased binding of annexin v to endothelial cells: a potential mechanism in atherothrombosis of patients with systemic lupus erythematosus. Arterioscler Thromb Vasc Biol: 2005; 25 01 198 203
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.1 , pp. 198-203
    • Cederholm, A.1    Svenungsson, E.2    Jensen-Urstad, K.3
  • 44
    • 0042925727 scopus 로고    scopus 로고
    • Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: Evidence from atomic force microscopy and functional assay
    • Rand J. H. Wu X. X. Quinn A. S., et al. Human monoclonal antiphospholipid antibodies disrupt the annexin A5 anticoagulant crystal shield on phospholipid bilayers: evidence from atomic force microscopy and functional assay. Am J Pathol: 2003; 163 03 1193 1200
    • (2003) Am J Pathol , vol.163 , Issue.3 , pp. 1193-1200
    • Rand, J.H.1    Wu, X.X.2    Quinn, A.S.3
  • 45
    • 33845568086 scopus 로고    scopus 로고
    • Annexin A5 binding to giant phospholipid vesicles is differentially affected by anti-beta2-glycoprotein i and anti-annexin A5 antibodies
    • Gaspersic N. Ambrozic A. Bozic B. Majhenc J. Svetina S. Rozman B. Annexin A5 binding to giant phospholipid vesicles is differentially affected by anti-beta2-glycoprotein I and anti-annexin A5 antibodies. Rheumatology (Oxford): 2007; 46 01 81 86
    • (2007) Rheumatology (Oxford) , vol.46 , Issue.1 , pp. 81-86
    • Gaspersic, N.1    Ambrozic, A.2    Bozic, B.3    Majhenc, J.4    Svetina, S.5    Rozman, B.6
  • 46
    • 0033625340 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein i (GPI) autoantibodies, annexin v binding and the anti-phospholipid syndrome
    • Hanly J. G. Smith S. A. Anti-beta2-glycoprotein I (GPI) autoantibodies, annexin V binding and the anti-phospholipid syndrome. Clin Exp Immunol: 2000; 120 03 537 543
    • (2000) Clin Exp Immunol , vol.120 , Issue.3 , pp. 537-543
    • Hanly, J.G.1    Smith, S.A.2
  • 47
    • 0032170963 scopus 로고    scopus 로고
    • Antiphospholipid antibodies accelerate plasma coagulation by inhibiting annexin-V binding to phospholipids: A lupus procoagulant phenomenon
    • Rand J. H. Wu X. X. Andree H. A., et al. Antiphospholipid antibodies accelerate plasma coagulation by inhibiting annexin-V binding to phospholipids: a lupus procoagulant phenomenon. Blood: 1998; 92 05 1652 1660
    • (1998) Blood , vol.92 , Issue.5 , pp. 1652-1660
    • Rand, J.H.1    Wu, X.X.2    Andree, H.A.3
  • 48
    • 33846936761 scopus 로고    scopus 로고
    • Correlation between antiphospholipid antibodies that recognize domain i of beta2-glycoprotein i and a reduction in the anticoagulant activity of annexin A5
    • de Laat B. Wu X. X. van Lummel M. Derksen R. H. de Groot P. G. Rand J. H. Correlation between antiphospholipid antibodies that recognize domain I of beta2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5. Blood: 2007; 109 04 1490 1494
    • (2007) Blood , vol.109 , Issue.4 , pp. 1490-1494
    • De Laat, B.1    Wu, X.X.2    Van Lummel, M.3    Derksen, R.H.4    De Groot, P.G.5    Rand, J.H.6
  • 49
    • 13544276197 scopus 로고    scopus 로고
    • IgG antibodies that recognize epitope Gly40-Arg43 in domain i of beta 2-glycoprotein i cause LAC, and their presence correlates strongly with thrombosis
    • de Laat B. Derksen R. H. Urbanus R. T. de Groot P. G. IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis. Blood: 2005; 105 04 1540 1545
    • (2005) Blood , vol.105 , Issue.4 , pp. 1540-1545
    • De Laat, B.1    Derksen, R.H.2    Urbanus, R.T.3    De Groot, P.G.4
  • 50
    • 70449390005 scopus 로고    scopus 로고
    • The association between circulating antibodies against domain i of beta2-glycoprotein i and thrombosis: An international multicenter study
    • de Laat B. Pengo V. Pabinger I., et al. The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study. J Thromb Haemost: 2009; 7 11 1767 1773
    • (2009) J Thromb Haemost , vol.7 , Issue.11 , pp. 1767-1773
    • De Laat, B.1    Pengo, V.2    Pabinger, I.3
  • 51
    • 0037385228 scopus 로고    scopus 로고
    • Annexin A5 is not essential for skeletal development
    • Brachvogel B. Dikschas J. Moch H., et al. Annexin A5 is not essential for skeletal development. Mol Cell Biol: 2003; 23 08 2907 2913
    • (2003) Mol Cell Biol , vol.23 , Issue.8 , pp. 2907-2913
    • Brachvogel, B.1    Dikschas, J.2    Moch, H.3
  • 52
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S. Takeda K. Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol: 2001; 2 08 675 680
    • (2001) Nat Immunol , vol.2 , Issue.8 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 53
    • 13444274668 scopus 로고    scopus 로고
    • Toll-like receptor downstream signaling
    • Kawai T. Akira S. Toll-like receptor downstream signaling. Arthritis Res Ther: 2005; 7 01 12 19
    • (2005) Arthritis Res Ther , vol.7 , Issue.1 , pp. 12-19
    • Kawai, T.1    Akira, S.2
  • 54
    • 0034753272 scopus 로고    scopus 로고
    • Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: Genetic and evolutionary studies
    • Beutler B. Du X. Poltorak A. Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies. J Endotoxin Res: 2001; 7 04 277 280
    • (2001) J Endotoxin Res , vol.7 , Issue.4 , pp. 277-280
    • Beutler, B.1    Du, X.2    Poltorak, A.3
  • 55
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • Raschi E. Testoni C. Bosisio D., et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood: 2003; 101 09 3495 3500
    • (2003) Blood , vol.101 , Issue.9 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3
  • 56
    • 1842413134 scopus 로고    scopus 로고
    • Thrombosis in primary antiphospholipid syndrome: A pivotal role for monocyte tissue factor expression
    • Cuadrado M. J. López-Pedrera C. Khamashta M. A., et al. Thrombosis in primary antiphospholipid syndrome: a pivotal role for monocyte tissue factor expression. Arthritis Rheum: 1997; 40 05 834 841
    • (1997) Arthritis Rheum , vol.40 , Issue.5 , pp. 834-841
    • Cuadrado, M.J.1    López-Pedrera, C.2    Khamashta, M.A.3
  • 57
    • 0032700453 scopus 로고    scopus 로고
    • Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome
    • Dobado-Berrios P. M. López-Pedrera C. Velasco F. Aguirre M. A. Torres A. Cuadrado M. J. Increased levels of tissue factor mRNA in mononuclear blood cells of patients with primary antiphospholipid syndrome. Thromb Haemost: 1999; 82 06 1578 1582
    • (1999) Thromb Haemost , vol.82 , Issue.6 , pp. 1578-1582
    • Dobado-Berrios, P.M.1    López-Pedrera, C.2    Velasco, F.3    Aguirre, M.A.4    Torres, A.5    Cuadrado, M.J.6
  • 59
    • 34547733912 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein i antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
    • Sorice M. Longo A. Capozzi A., et al. Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum: 2007; 56 08 2687 2697
    • (2007) Arthritis Rheum , vol.56 , Issue.8 , pp. 2687-2697
    • Sorice, M.1    Longo, A.2    Capozzi, A.3
  • 60
    • 84868108264 scopus 로고    scopus 로고
    • Autoantibodies specific to a peptide of β2-glycoprotein i cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes
    • Colasanti T. Alessandri C. Capozzi A., et al. Autoantibodies specific to a peptide of β2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes. Blood: 2012; 120 16 3360 3370
    • (2012) Blood , vol.120 , Issue.16 , pp. 3360-3370
    • Colasanti, T.1    Alessandri, C.2    Capozzi, A.3
  • 61
    • 58849090583 scopus 로고    scopus 로고
    • Toll-like receptors: Another player in the pathogenesis of the anti-phospholipid syndrome
    • Raschi E. Borghi M. O. Grossi C. Broggini V. Pierangeli S. Meroni P. L. Toll-like receptors: another player in the pathogenesis of the anti-phospholipid syndrome. Lupus: 2008; 17 10 937 942
    • (2008) Lupus , vol.17 , Issue.10 , pp. 937-942
    • Raschi, E.1    Borghi, M.O.2    Grossi, C.3    Broggini, V.4    Pierangeli, S.5    Meroni, P.L.6
  • 62
    • 34250721890 scopus 로고    scopus 로고
    • Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
    • Pierangeli S. S. Vega-Ostertag M. E. Raschi E., et al. Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann Rheum Dis: 2007; 66 10 1327 1333
    • (2007) Ann Rheum Dis , vol.66 , Issue.10 , pp. 1327-1333
    • Pierangeli, S.S.1    Vega-Ostertag, M.E.2    Raschi, E.3
  • 63
    • 3242807395 scopus 로고    scopus 로고
    • Functions of toll-like receptors: Lessons from KO mice
    • Akira S. Takeda K. Functions of toll-like receptors: lessons from KO mice. C R Biol: 2004; 327 06 581 589
    • (2004) C R Biol , vol.327 , Issue.6 , pp. 581-589
    • Akira, S.1    Takeda, K.2
  • 64
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Hoshino K. Takeuchi O. Kawai T., et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol: 1999; 162 07 3749 3752
    • (1999) J Immunol , vol.162 , Issue.7 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3
  • 65
    • 84960968008 scopus 로고    scopus 로고
    • Cofactor-independent human antiphospholipid antibodies induce venous thrombosis in mice
    • Manukyan D. Müller-Calleja N. Jäckel S., et al. Cofactor-independent human antiphospholipid antibodies induce venous thrombosis in mice. J Thromb Haemost: 2016; 14 05 1011 1020
    • (2016) J Thromb Haemost , vol.14 , Issue.5 , pp. 1011-1020
    • Manukyan, D.1    Müller-Calleja, N.2    Jäckel, S.3
  • 66
    • 59649114623 scopus 로고    scopus 로고
    • Tissue factor in antiphospholipid antibody-induced pregnancy loss: A pro-inflammatory molecule
    • Girardi G. Mackman N. Tissue factor in antiphospholipid antibody-induced pregnancy loss: a pro-inflammatory molecule. Lupus: 2008; 17 10 931 936
    • (2008) Lupus , vol.17 , Issue.10 , pp. 931-936
    • Girardi, G.1    Mackman, N.2
  • 68
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • Satta N. Dunoyer-Geindre S. Reber G., et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood: 2007; 109 04 1507 1514
    • (2007) Blood , vol.109 , Issue.4 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3
  • 69
    • 79956312573 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates the activation of human monocytes and endothelial cells by antiphospholipid antibodies
    • Satta N. Kruithof E. K. Fickentscher C., et al. Toll-like receptor 2 mediates the activation of human monocytes and endothelial cells by antiphospholipid antibodies. Blood: 2011; 117 20 5523 5531
    • (2011) Blood , vol.117 , Issue.20 , pp. 5523-5531
    • Satta, N.1    Kruithof, E.K.2    Fickentscher, C.3
  • 70
    • 84901193062 scopus 로고    scopus 로고
    • NF-κB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes
    • Brandt K. J. Fickentscher C. Boehlen F. Kruithof E. K. de Moerloose P. NF-κB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes. J Thromb Haemost: 2014; 12 05 779 791
    • (2014) J Thromb Haemost , vol.12 , Issue.5 , pp. 779-791
    • Brandt, K.J.1    Fickentscher, C.2    Boehlen, F.3    Kruithof, E.K.4    De Moerloose, P.5
  • 71
    • 84931291695 scopus 로고    scopus 로고
    • Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: Implications for the antiphospholipid syndrome
    • Müller-Calleja N. Köhler A. Siebald B., et al. Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: implications for the antiphospholipid syndrome. Thromb Haemost: 2015; 113 05 1071 1083
    • (2015) Thromb Haemost , vol.113 , Issue.5 , pp. 1071-1083
    • Müller-Calleja, N.1    Köhler, A.2    Siebald, B.3
  • 72
    • 84925581582 scopus 로고    scopus 로고
    • Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome
    • Benhamou Y. Bellien J. Armengol G., et al. Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome. Arthritis Rheumatol: 2014; 66 11 3210 3220
    • (2014) Arthritis Rheumatol , vol.66 , Issue.11 , pp. 3210-3220
    • Benhamou, Y.1    Bellien, J.2    Armengol, G.3
  • 73
    • 34247557490 scopus 로고    scopus 로고
    • The LDL receptor-related protein (LRP) family: An old family of proteins with new physiological functions
    • May P. Woldt E. Matz R. L. Boucher P. The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions. Ann Med: 2007; 39 03 219 228
    • (2007) Ann Med , vol.39 , Issue.3 , pp. 219-228
    • May, P.1    Woldt, E.2    Matz, R.L.3    Boucher, P.4
  • 74
    • 33645211958 scopus 로고    scopus 로고
    • Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts
    • Mayer H. Duit S. Hauser C. Schneider W. J. Nimpf J. Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts. Mol Cell Biol: 2006; 26 01 19 27
    • (2006) Mol Cell Biol , vol.26 , Issue.1 , pp. 19-27
    • Mayer, H.1    Duit, S.2    Hauser, C.3    Schneider, W.J.4    Nimpf, J.5
  • 75
    • 0032855538 scopus 로고    scopus 로고
    • Identification and characterization of LRP8 (apoER2) in human blood platelets
    • Riddell D. R. Vinogradov D. V. Stannard A. K. Chadwick N. Owen J. S. Identification and characterization of LRP8 (apoER2) in human blood platelets. J Lipid Res: 1999; 40 10 1925 1930
    • (1999) J Lipid Res , vol.40 , Issue.10 , pp. 1925-1930
    • Riddell, D.R.1    Vinogradov, D.V.2    Stannard, A.K.3    Chadwick, N.4    Owen, J.S.5
  • 76
    • 58549121206 scopus 로고    scopus 로고
    • Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells
    • Yang X. V. Banerjee Y. Fernández J. A., et al. Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells. Proc Natl Acad Sci U S A: 2009; 106 01 274 279
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.1 , pp. 274-279
    • Yang, X.V.1    Banerjee, Y.2    Fernández, J.A.3
  • 77
    • 84963800435 scopus 로고    scopus 로고
    • ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice
    • Ulrich V. Gelber S. E. Vukelic M., et al. ApoE receptor 2 mediation of trophoblast dysfunction and pregnancy complications induced by antiphospholipid antibodies in mice. Arthritis Rheumatol: 2016; 68 03 730 739
    • (2016) Arthritis Rheumatol , vol.68 , Issue.3 , pp. 730-739
    • Ulrich, V.1    Gelber, S.E.2    Vukelic, M.3
  • 79
    • 58649099165 scopus 로고    scopus 로고
    • Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis
    • Robertson J. O. Li W. Silverstein R. L. Topol E. J. Smith J. D. Deficiency of LRP8 in mice is associated with altered platelet function and prolonged time for in vivo thrombosis. Thromb Res: 2009; 123 04 644 652
    • (2009) Thromb Res , vol.123 , Issue.4 , pp. 644-652
    • Robertson, J.O.1    Li, W.2    Silverstein, R.L.3    Topol, E.J.4    Smith, J.D.5
  • 80
    • 84907289344 scopus 로고    scopus 로고
    • Genetic variants of ApoE and ApoER2 differentially modulate endothelial function
    • Ulrich V. Konaniah E. S. Herz J., et al. Genetic variants of ApoE and ApoER2 differentially modulate endothelial function. Proc Natl Acad Sci U S A: 2014; 111 37 13493 13498
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.37 , pp. 13493-13498
    • Ulrich, V.1    Konaniah, E.S.2    Herz, J.3
  • 82
    • 0141445991 scopus 로고    scopus 로고
    • Dimers of beta 2-glycoprotein i increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein e receptor 2′
    • Lutters B. C. Derksen R. H. Tekelenburg W. L. Lenting P. J. Arnout J. de Groot P. G. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2′ J Biol Chem: 2003; 278 36 33831 33838
    • (2003) J Biol Chem , vol.278 , Issue.36 , pp. 33831-33838
    • Lutters, B.C.1    Derksen, R.H.2    Tekelenburg, W.L.3    Lenting, P.J.4    Arnout, J.5    De Groot, P.G.6
  • 83
    • 47649130477 scopus 로고    scopus 로고
    • Platelet activation by dimeric beta2-glycoprotein i requires signaling via both glycoprotein Ibalpha and apolipoprotein e receptor 2′
    • Urbanus R. T. Pennings M. T. Derksen R. H. de Groot P. G. Platelet activation by dimeric beta2-glycoprotein I requires signaling via both glycoprotein Ibalpha and apolipoprotein E receptor 2′ J Thromb Haemost: 2008; 6 08 1405 1412
    • (2008) J Thromb Haemost , vol.6 , Issue.8 , pp. 1405-1412
    • Urbanus, R.T.1    Pennings, M.T.2    Derksen, R.H.3    De Groot, P.G.4
  • 84
    • 78650961942 scopus 로고    scopus 로고
    • Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2
    • Ramesh S. Morrell C. N. Tarango C., et al. Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2. J Clin Invest: 2011; 121 01 120 131
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 120-131
    • Ramesh, S.1    Morrell, C.N.2    Tarango, C.3
  • 85
    • 79251578627 scopus 로고    scopus 로고
    • Apolipoprotein e receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
    • Romay-Penabad Z. Aguilar-Valenzuela R. Urbanus R. T., et al. Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome. Blood: 2011; 117 04 1408 1414
    • (2011) Blood , vol.117 , Issue.4 , pp. 1408-1414
    • Romay-Penabad, Z.1    Aguilar-Valenzuela, R.2    Urbanus, R.T.3
  • 86
    • 84897834063 scopus 로고    scopus 로고
    • Inhibition of thrombotic properties of persistent autoimmune anti-β2GPI antibodies in the mouse model of antiphospholipid syndrome
    • Kolyada A. Porter A. Beglova N. Inhibition of thrombotic properties of persistent autoimmune anti-β2GPI antibodies in the mouse model of antiphospholipid syndrome. Blood: 2014; 123 07 1090 1097
    • (2014) Blood , vol.123 , Issue.7 , pp. 1090-1097
    • Kolyada, A.1    Porter, A.2    Beglova, N.3
  • 87
    • 0032510559 scopus 로고    scopus 로고
    • A lipid associated with the antiphospholipid syndrome regulates endosome structure and function
    • Kobayashi T. Stang E. Fang K. S. de Moerloose P. Parton R. G. Gruenberg J. A lipid associated with the antiphospholipid syndrome regulates endosome structure and function. Nature: 1998; 392 (6672): 193 197
    • (1998) Nature , vol.392 , Issue.6672 , pp. 193-197
    • Kobayashi, T.1    Stang, E.2    Fang, K.S.3    De Moerloose, P.4    Parton, R.G.5    Gruenberg, J.6
  • 88
    • 84904581191 scopus 로고    scopus 로고
    • Inhibition of the mTORC pathway in the antiphospholipid syndrome
    • Canaud G. Bienaimé F. Tabarin F., et al. Inhibition of the mTORC pathway in the antiphospholipid syndrome. N Engl J Med: 2014; 371 04 303 312
    • (2014) N Engl J Med , vol.371 , Issue.4 , pp. 303-312
    • Canaud, G.1    Bienaimé, F.2    Tabarin, F.3
  • 89
    • 84922625916 scopus 로고    scopus 로고
    • AKT/mTORC pathway in antiphospholipid-related vasculopathy: A new player in the game
    • Canaud G. Legendre C. Terzi F. AKT/mTORC pathway in antiphospholipid-related vasculopathy: a new player in the game. Lupus: 2015; 24 03 227 230
    • (2015) Lupus , vol.24 , Issue.3 , pp. 227-230
    • Canaud, G.1    Legendre, C.2    Terzi, F.3
  • 90
    • 0346969977 scopus 로고    scopus 로고
    • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    • Girardi G. Berman J. Redecha P., et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest: 2003; 112 11 1644 1654
    • (2003) J Clin Invest , vol.112 , Issue.11 , pp. 1644-1654
    • Girardi, G.1    Berman, J.2    Redecha, P.3
  • 91
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi G. Redecha P. Salmon J. E. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med: 2004; 10 11 1222 1226
    • (2004) Nat Med , vol.10 , Issue.11 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 92
    • 55849112296 scopus 로고    scopus 로고
    • Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome
    • Redecha P. Franzke C. W. Ruf W. Mackman N. Girardi G. Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest: 2008; 118 10 3453 3461
    • (2008) J Clin Invest , vol.118 , Issue.10 , pp. 3453-3461
    • Redecha, P.1    Franzke, C.W.2    Ruf, W.3    Mackman, N.4    Girardi, G.5
  • 93
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • Pierangeli S. S. Girardi G. Vega-Ostertag M. Liu X. Espinola R. G. Salmon J. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum: 2005; 52 07 2120 2124
    • (2005) Arthritis Rheum , vol.52 , Issue.7 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 94
    • 34948885608 scopus 로고    scopus 로고
    • C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies
    • Romay-Penabad Z. Liu X. X. Montiel-Manzano G. Papalardo De Martínez E. Pierangeli S. S. C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies. Ann N Y Acad Sci: 2007; 1108 554 566
    • (2007) Ann N y Acad Sci , vol.1108 , pp. 554-566
    • Romay-Penabad, Z.1    Liu, X.X.2    Montiel-Manzano, G.3    Papalardo De Martínez, E.4    Pierangeli, S.S.5
  • 95
    • 84869382834 scopus 로고    scopus 로고
    • C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies
    • Carrera-Marín A. Romay-Penabad Z. Papalardo E., et al. C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies. Lupus: 2012; 21 14 1497 1505
    • (2012) Lupus , vol.21 , Issue.14 , pp. 1497-1505
    • Carrera-Marín, A.1    Romay-Penabad, Z.2    Papalardo, E.3
  • 96
    • 0032833085 scopus 로고    scopus 로고
    • Isolation and characterization of two human monoclonal anti-phospholipid IgG from patients with autoimmune disease
    • von Landenberg C. Lackner K. J. von Landenberg P. Lang B. Schmitz G. Isolation and characterization of two human monoclonal anti-phospholipid IgG from patients with autoimmune disease. J Autoimmun: 1999; 13 02 215 223
    • (1999) J Autoimmun , vol.13 , Issue.2 , pp. 215-223
    • Von Landenberg, C.1    Lackner, K.J.2    Von Landenberg, P.3    Lang, B.4    Schmitz, G.5
  • 97
    • 0034030622 scopus 로고    scopus 로고
    • Analysis of prothrombotic effects of two human monoclonal IgG antiphospholipid antibodies of apparently similar specificity
    • Lackner K. J. von Landenberg C. Barlage S. Schmitz G. Analysis of prothrombotic effects of two human monoclonal IgG antiphospholipid antibodies of apparently similar specificity. Thromb Haemost: 2000; 83 04 583 588
    • (2000) Thromb Haemost , vol.83 , Issue.4 , pp. 583-588
    • Lackner, K.J.1    Von Landenberg, C.2    Barlage, S.3    Schmitz, G.4
  • 98
    • 0031778067 scopus 로고    scopus 로고
    • Human anticardiolipin monoclonal autoantibodies cause placental necrosis and fetal loss in BALB/c mice
    • Ikematsu W. Luan F. L. La Rosa L., et al. Human anticardiolipin monoclonal autoantibodies cause placental necrosis and fetal loss in BALB/c mice. Arthritis Rheum: 1998; 41 06 1026 1039
    • (1998) Arthritis Rheum , vol.41 , Issue.6 , pp. 1026-1039
    • Ikematsu, W.1    Luan, F.L.2    La Rosa, L.3
  • 99
    • 84904906141 scopus 로고    scopus 로고
    • Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS
    • Proulle V. Furie R. A. Merrill-Skoloff G. Furie B. C. Furie B. Platelets are required for enhanced activation of the endothelium and fibrinogen in a mouse thrombosis model of APS. Blood: 2014; 124 04 611 622
    • (2014) Blood , vol.124 , Issue.4 , pp. 611-622
    • Proulle, V.1    Furie, R.A.2    Merrill-Skoloff, G.3    Furie, B.C.4    Furie, B.5
  • 100
    • 84883058074 scopus 로고    scopus 로고
    • The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome
    • Nishimura M. Nii T. Trimova G., et al. The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome. J Nephropathol: 2013; 2 02 114 121
    • (2013) J Nephropathol , vol.2 , Issue.2 , pp. 114-121
    • Nishimura, M.1    Nii, T.2    Trimova, G.3


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