NF-κB is activated from endosomal compartments in antiphospholipid antibodies-treated human monocytes

Journal of Thrombosis and Haemostasis

Volumn 12, Issue 5, 2014, Pages 779-791

  Brandt, K J ^a   Fickentscher, C ^a   Boehlen, F ^a   Kruithof, E K O ^a   De Moerloose, P ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Antiphospholipid antibodies; Innate immunity; Monocytes; NF B; Toll like receptors

Indexed keywords

BETA2 GLYCOPROTEIN 1; BETA2 GLYCOPROTEIN 1 ANTIBODY; BLOCKING ANTIBODY; CD14 ANTIGEN; CLATHRIN; DYNAMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; INTERFERON REGULATORY FACTOR 3; MESSENGER RNA; NEUTRALIZING ANTIBODY; PHOSPHOLIPID ANTIBODY; SMALL INTERFERING RNA; THROMBOPLASTIN; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR; NFKB1 PROTEIN, HUMAN; TLR6 PROTEIN, HUMAN; TOLL LIKE RECEPTOR;

ANTIPHOSPHOLIPID SYNDROME; ARTERY THROMBOSIS; ARTICLE; AUTOIMMUNE DISEASE; BLOOD BUFFY COAT; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENDOCYTOSIS; ENDOSOME; FETUS WASTAGE; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTERNALIZATION; MONOCYTE; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; HEK293 CELL LINE; IMMUNOLOGY; INFLAMMATION; METABOLISM;

ANTIBODIES, ANTIPHOSPHOLIPID; ANTIGENS, CD14; AUTOIMMUNE DISEASES; CLATHRIN; ENDOCYTOSIS; ENDOSOMES; GENE EXPRESSION REGULATION; GENE SILENCING; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; MICROSCOPY, CONFOCAL; MONOCYTES; NF-KAPPA B P50 SUBUNIT; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 6; TOLL-LIKE RECEPTORS; VENOUS THROMBOSIS;

EID: 84901193062     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12536     Document Type: Article

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