Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells

Blood

Volumn 118, Issue 8, 2011, Pages 2322-2332

  Prinz, Nadine ^a   Clemens, Natascha ^a   Strand, Dennis ^a   Pütz, Inge ^a   Lorenz, Mareike ^a   Daiber, Andreas ^a   Stein, Pamela ^a   Degreif, Adriana ^a   Radsak, Markus ^a   Schild, Hansjörg ^a   Bauer, Stefan ^b   Von Landenberg, Philipp ^a   Lackner, Karl J ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; MESSENGER RNA; PHOSPHOLIPID ANTIBODY; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RIBONUCLEASE; RNA; SUPEROXIDE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOPLASMIC RETICULUM; ENDOSOME; ENZYME ACTIVATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MALE; MONOCYTE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMATIC MUTATION;

EID: 80052140024     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-01-330639     Document Type: Article

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