메뉴 건너뛰기




Volumn 21, Issue 14, 2012, Pages 1497-1505

C6 knock-out mice are protected from thrombophilia mediated by antiphospholipid antibodies

Author keywords

Anticardiolipin antibodies; antiphospholipid syndrome; complement activation; lupus anticoagulant; thrombosis

Indexed keywords

ANTIBODY; BETA 2 GLYCOPROTEIN ANTIBODY; CARDIOLIPIN ANTIBODY; COMPLEMENT COMPONENT C6; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PHOSPHOLIPID ANTIBODY; THROMBOPLASTIN; UNCLASSIFIED DRUG;

EID: 84869382834     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203312458839     Document Type: Article
Times cited : (51)

References (51)
  • 1
    • 0023434038 scopus 로고
    • Syndrome of the black swan
    • Harris EN. Syndrome of the black swan. Br J Rheumatol. 1987 ; 26: 324-326
    • (1987) Br J Rheumatol , vol.26 , pp. 324-326
    • Harris, E.N.1
  • 2
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006 ; 4: 295-306
    • (2006) J Thromb Haemost , vol.4 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3    Branch, D.W.4    Brey, R.L.5    Cervera, R.6
  • 3
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • Pierangeli SS, Colden-Stanfield M, Liu X, et al. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation. 1999 ; 99: 1997-2002
    • (1999) Circulation , vol.99 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.3
  • 4
    • 0026322836 scopus 로고
    • Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies
    • Blank M, Cohen J, Toder V, Shoenfeld Y. Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci USA. 1991 ; 88: 3069-3073
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3069-3073
    • Blank, M.1    Cohen, J.2    Toder, V.3    Shoenfeld, Y.4
  • 5
    • 0032569480 scopus 로고    scopus 로고
    • Action of anticardiolipin and antibodies to β2glycoprotein-I on trophoblast proliferation as a mechanism for fetal death
    • Chamley LW, Duncalf AM, Mitchell MD, Johnson PM. Action of anticardiolipin and antibodies to β2glycoprotein-I on trophoblast proliferation as a mechanism for fetal death. Lancet. 1998 ; 352: 1037-1038
    • (1998) Lancet , vol.352 , pp. 1037-1038
    • Chamley, L.W.1    Duncalf, A.M.2    Mitchell, M.D.3    Johnson, P.M.4
  • 6
    • 0142166253 scopus 로고    scopus 로고
    • E-selectin mediates pathogenic effects of antiphospholipid antibodies
    • Espinola RG, Liu X, Colden-Stanfield M, Hall J, et al. E-selectin mediates pathogenic effects of antiphospholipid antibodies. J Thromb Haemost. 2002 ; 1: 843-848
    • (2002) J Thromb Haemost , vol.1 , pp. 843-848
    • Espinola, R.G.1    Liu, X.2    Colden-Stanfield, M.3    Hall, J.4
  • 7
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • Vega-Ostertag ME, Casper K, Swerlick R, et al. Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum. 2005 ; 52: 1545-1554
    • (2005) Arthritis Rheum , vol.52 , pp. 1545-1554
    • Vega-Ostertag, M.E.1    Casper, K.2    Swerlick, R.3
  • 8
    • 0030897237 scopus 로고    scopus 로고
    • Endothelial cells as target for antiphospholipid antibodies - Human polyclonal and monoclonal anti-β2. glycoprotein i antibodies react in vitro with endothelial cells through adherent β2. glycoprotein i and induce endothelial activation
    • Del Papa N, Guidali L, Sala A, et al. Endothelial cells as target for antiphospholipid antibodies - Human polyclonal and monoclonal anti-β2. glycoprotein I antibodies react in vitro with endothelial cells through adherent β2. glycoprotein I and induce endothelial activation. Arthritis Rheum. 1997 ; 40: 551-561
    • (1997) Arthritis Rheum , vol.40 , pp. 551-561
    • Del Papa, N.1    Guidali, L.2    Sala, A.3
  • 9
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R, LaSala JM, Lo SK, et al. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest. 1995 ; 96: 2211-2219
    • (1995) J Clin Invest , vol.96 , pp. 2211-2219
    • Simantov, R.1    Lasala, J.M.2    Lo, S.K.3
  • 10
    • 0035793334 scopus 로고    scopus 로고
    • Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin
    • Pierangeli SS, Espinola RG, Liu X, Harris EN. Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin. Circ Res. 2001 ; 88: 245-250
    • (2001) Circ Res , vol.88 , pp. 245-250
    • Pierangeli, S.S.1    Espinola, R.G.2    Liu, X.3    Harris, E.N.4
  • 11
    • 1842413134 scopus 로고    scopus 로고
    • Thrombosis in primary antiphospholipid syndrome - A pivotal role for monocyte tissue factor expression
    • Cuadrado MJ, López-Pedrera C, Khamashta MA, et al. Thrombosis in primary antiphospholipid syndrome - A pivotal role for monocyte tissue factor expression. Arthritis Rheum. 1997 ; 40: 834-841
    • (1997) Arthritis Rheum , vol.40 , pp. 834-841
    • Cuadrado, M.J.1    López-Pedrera, C.2    Khamashta, M.A.3
  • 12
    • 4444273214 scopus 로고    scopus 로고
    • Intracellular events in antiphospholipid-mediated platelet activation
    • Vega-Ostertag M, Harris EN, Pierangeli SS. Intracellular events in antiphospholipid-mediated platelet activation. Arthritis Rheum. 2004 ; 50: 2911-2919
    • (2004) Arthritis Rheum , vol.50 , pp. 2911-2919
    • Vega-Ostertag, M.1    Harris, E.N.2    Pierangeli, S.S.3
  • 13
    • 14744275911 scopus 로고    scopus 로고
    • Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprous related antiphospholipid antibodies
    • Forastiero RR, Martinuzzo ME, De Larranaga GF. Circulating levels of tissue factor and proinflammatory cytokines in patients with primary antiphospholipid syndrome or leprous related antiphospholipid antibodies. Lupus. 2005 ; 14: 129-136
    • (2005) Lupus , vol.14 , pp. 129-136
    • Forastiero, R.R.1    Martinuzzo, M.E.2    De Larranaga, G.F.3
  • 14
    • 0033694198 scopus 로고    scopus 로고
    • Systemic endothelial cell markers in antiphospholipid syndrome
    • Williams FM, Parmar K, Hughes GR, Hunt BJ. Systemic endothelial cell markers in antiphospholipid syndrome. Thromb Haemost. 2000 ; 84: 742-746
    • (2000) Thromb Haemost , vol.84 , pp. 742-746
    • Williams, F.M.1    Parmar, K.2    Hughes, G.R.3    Hunt, B.J.4
  • 15
    • 7244237671 scopus 로고    scopus 로고
    • Fluvastatin inhibits upregulation of tissue factor expression by antiphospholipid antibodies on endothelial cells
    • Ferrara DE, Swerlick R, Casper K, et al. Fluvastatin inhibits upregulation of tissue factor expression by antiphospholipid antibodies on endothelial cells. J Thromb Haemost. 2004 ; 2: 1558-1563
    • (2004) J Thromb Haemost , vol.2 , pp. 1558-1563
    • Ferrara, D.E.1    Swerlick, R.2    Casper, K.3
  • 16
    • 34948875756 scopus 로고    scopus 로고
    • In vivo effects of an inhibitor of nuclear factor-kappa B on thrombogenic properties of antiphospholipid antibodies
    • Montiel-Manzano G, Romay-Penabad Z, Papalardo de Martinez E, et al. In vivo effects of an inhibitor of nuclear factor-kappa B on thrombogenic properties of antiphospholipid antibodies. Ann N Y Acad Sci. 2007 ; 1108: 540-553
    • (2007) Ann N y Acad Sci , vol.1108 , pp. 540-553
    • Montiel-Manzano, G.1    Romay-Penabad, Z.2    Papalardo De Martinez, E.3
  • 17
    • 0036847630 scopus 로고    scopus 로고
    • NFκB is an essential intermediate in the activation of endothelial cells by anti- β2glycoprotein i antibodies
    • Dunoyer-Geindre S, De Moerloose P, Galve-de Rochemonteiz B, et al. NFκB is an essential intermediate in the activation of endothelial cells by anti- β2glycoprotein I antibodies. Thromb Haemost. 2002 ; 88: 851-857
    • (2002) Thromb Haemost , vol.88 , pp. 851-857
    • Dunoyer-Geindre, S.1    De Moerloose, P.2    Galve-De Rochemonteiz, B.3
  • 18
    • 8344267910 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-β2glycoprotein i antibodies
    • Bohgaki M, Atsumi T, Yamashita Y, et al. The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-β2glycoprotein I antibodies. Int Immunol. 2004 ; 16: 1632-1641
    • (2004) Int Immunol , vol.16 , pp. 1632-1641
    • Bohgaki, M.1    Atsumi, T.2    Yamashita, Y.3
  • 19
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood. 2009 ; 114: 3074-3083
    • (2009) Blood , vol.114 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 20
    • 34250721890 scopus 로고    scopus 로고
    • Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
    • Pierangeli SS, Vega-Ostertag ME, Raschi E, et al. Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann Rheum Dis. 2007 ; 66: 1327-1333
    • (2007) Ann Rheum Dis , vol.66 , pp. 1327-1333
    • Pierangeli, S.S.1    Vega-Ostertag, M.E.2    Raschi, E.3
  • 21
    • 79251578627 scopus 로고    scopus 로고
    • Apolipoprotein e receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
    • Romay-Penabad Z, Aguilar-Valenzuela R, Urbanus RT, et al. Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome. Blood. 2011 ; 117: 1408-1414
    • (2011) Blood , vol.117 , pp. 1408-1414
    • Romay-Penabad, Z.1    Aguilar-Valenzuela, R.2    Urbanus, R.T.3
  • 22
    • 77957068516 scopus 로고    scopus 로고
    • Membrane attack by complement assembly and biology of terminal complement complexes
    • Shin ML, Ros HG, Nicolescu FI, et al. Membrane attack by complement assembly and biology of terminal complement complexes. Biomembranes. 1996 ; 4: 123-129
    • (1996) Biomembranes , vol.4 , pp. 123-129
    • Shin, M.L.1    Ros, H.G.2    Nicolescu, F.I.3
  • 23
    • 0023091222 scopus 로고
    • Effect of late complement components C5b-9 on human monocytes: Release of prostanoids, oxygen radicals and of a factor inducing cell proliferation
    • Hansch GM, Seitz M, Betz M. Effect of late complement components C5b-9 on human monocytes: release of prostanoids, oxygen radicals and of a factor inducing cell proliferation. Int Arch Allergy Immunol. 1987 ; 82: 317-320
    • (1987) Int Arch Allergy Immunol , vol.82 , pp. 317-320
    • Hansch, G.M.1    Seitz, M.2    Betz, M.3
  • 24
    • 0031045303 scopus 로고    scopus 로고
    • C5a induces tissue factor activity on endothelial cells
    • Ikeda K, Nagasawa K, Horiuchi T, et al. C5a induces tissue factor activity on endothelial cells. Thromb Haemost. 1997 ; 77: 394-398
    • (1997) Thromb Haemost , vol.77 , pp. 394-398
    • Ikeda, K.1    Nagasawa, K.2    Horiuchi, T.3
  • 25
    • 0028881851 scopus 로고
    • Complement-mediated regulation of tissue factor activity in endothelium
    • Saadi S, Holznecht RA, Patte CP, et al. Complement-mediated regulation of tissue factor activity in endothelium. J Exp Med. 1995 ; 182: 1807-1814
    • (1995) J Exp Med , vol.182 , pp. 1807-1814
    • Saadi, S.1    Holznecht, R.A.2    Patte, C.P.3
  • 26
    • 0032570062 scopus 로고    scopus 로고
    • Anaphylotoxins C5a and C3a induce nuclear factor kappa B activation in human peripheral blood monocytes
    • Pan ZK. Anaphylotoxins C5a and C3a induce nuclear factor kappa B activation in human peripheral blood monocytes. Biochim Biophys Acta. 1998 ; 1443: 90-98
    • (1998) Biochim Biophys Acta , vol.1443 , pp. 90-98
    • Pan, Z.K.1
  • 27
    • 4143060419 scopus 로고    scopus 로고
    • C5a differentially stimulates the ERK1/2 and p38 MAPK phosphorylation through independent signaling pathways to induced chemotactic migration in RAW264.7 macrophages
    • Chiou W, Tsai H, Yang L, Tsai W. C5a differentially stimulates the ERK1/2 and p38 MAPK phosphorylation through independent signaling pathways to induced chemotactic migration in RAW264.7 macrophages. Int Immunopharmacol. 2004 ; 4: 1329-1341
    • (2004) Int Immunopharmacol , vol.4 , pp. 1329-1341
    • Chiou, W.1    Tsai, H.2    Yang, L.3    Tsai, W.4
  • 28
    • 0031900114 scopus 로고    scopus 로고
    • CD59 protects glomerular endothelial cells from immune-mediated thrombotic microangiopathy in rats
    • Nangaku M, Alpers CE, Pippin J, Shankland SJ, Kurokawa K, Adler S, et al. CD59 protects glomerular endothelial cells from immune-mediated thrombotic microangiopathy in rats. J Am Soc Nephrol. 1998 ; 9: 590-597
    • (1998) J Am Soc Nephrol , vol.9 , pp. 590-597
    • Nangaku, M.1    Alpers, C.E.2    Pippin, J.3    Shankland, S.J.4    Kurokawa, K.5    Adler, S.6
  • 29
    • 0036839070 scopus 로고    scopus 로고
    • Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis
    • Salmon JE, Girardi G, Holers VM. Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis. Ann Rheum Dis. 2002 ; 61: ii46 - ii50
    • (2002) Ann Rheum Dis , vol.61
    • Salmon, J.E.1    Girardi, G.2    Holers, V.M.3
  • 30
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • Pierangeli SS, Girardi G, Vega-Ostertag M, et al. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis and Rheumatism. 2005 ; 52: 2120-2124
    • (2005) Arthritis and Rheumatism , vol.52 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3
  • 31
    • 0037148520 scopus 로고    scopus 로고
    • Complement C3 activation is required for antiphospholipid antibody-induced fetal loss
    • Holers VM, Girardi G, Mo L, et al. Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med. 2002 ; 195: 211-220
    • (2002) J Exp Med , vol.195 , pp. 211-220
    • Holers, V.M.1    Girardi, G.2    Mo, L.3
  • 32
    • 34948885608 scopus 로고    scopus 로고
    • C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies
    • Romay-Penabad Z, Liu XX, Montiel-Manzano G, et al. C5a receptor-deficient mice are protected from thrombophilia and endothelial cell activation induced by some antiphospholipid antibodies. Ann N Y Acad Sci. 2007 ; 1108: 554-566
    • (2007) Ann N y Acad Sci , vol.1108 , pp. 554-566
    • Romay-Penabad, Z.1    Liu, X.X.2    Montiel-Manzano, G.3
  • 33
    • 34948903311 scopus 로고    scopus 로고
    • Tissue factor: A link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury
    • Redecha P, Tilley R, Tencati M, et al. Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood. 2007 ; 110: 2423-2431
    • (2007) Blood , vol.110 , pp. 2423-2431
    • Redecha, P.1    Tilley, R.2    Tencati, M.3
  • 34
    • 9144243607 scopus 로고    scopus 로고
    • Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation
    • Girardi G, Redecha P, Salmon JE. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med. 2004 ; 10: 1222-1226
    • (2004) Nat Med , vol.10 , pp. 1222-1226
    • Girardi, G.1    Redecha, P.2    Salmon, J.E.3
  • 35
    • 0017184389 scopus 로고
    • A refined and sensitive method for the Quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A refined and sensitive method for the Quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 ; 72: 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 36
    • 43149093564 scopus 로고    scopus 로고
    • A protocol for determination of anticardiolipin antibodies by ELISA
    • Pierangeli SS, Harris EN. A protocol for determination of anticardiolipin antibodies by ELISA. Nat Protoc. 2008 ; 3: 840-848
    • (2008) Nat Protoc , vol.3 , pp. 840-848
    • Pierangeli, S.S.1    Harris, E.N.2
  • 37
    • 27144494245 scopus 로고    scopus 로고
    • Thrombus formation induced by antibodies to beta2-glycoprotein i is complement dependent and requires a priming factor
    • Fischetti F, Durigutto P, Pellis V, et al. Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor. Blood. 2005 ; 106: 2340-2346
    • (2005) Blood , vol.106 , pp. 2340-2346
    • Fischetti, F.1    Durigutto, P.2    Pellis, V.3
  • 38
    • 0028787634 scopus 로고
    • Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome
    • Pierangeli SS, Liu XW, Barker JH, et al. Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome. Thromb Haemost. 1995 ; 74: 1361-1367
    • (1995) Thromb Haemost , vol.74 , pp. 1361-1367
    • Pierangeli, S.S.1    Liu, X.W.2    Barker, J.H.3
  • 39
    • 11144248088 scopus 로고    scopus 로고
    • Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall
    • Day SM, Reeve JL, Pedersen B, et al. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood. 2005 ; 105: 192-198
    • (2005) Blood , vol.105 , pp. 192-198
    • Day, S.M.1    Reeve, J.L.2    Pedersen, B.3
  • 40
    • 33644845852 scopus 로고    scopus 로고
    • Quantitative 3D fluorescence technique for the analysis of en face preparations of arterial walls using quantum dot nanocrystals and two-photon excitation laser scanning microscopy
    • Ferrara DE, Weiss D, Carnell PH, et al. Quantitative 3D fluorescence technique for the analysis of en face preparations of arterial walls using quantum dot nanocrystals and two-photon excitation laser scanning microscopy. Am J Physiol Regulatory Integrative Comp Physiol. 2006 ; 290: 114-123
    • (2006) Am J Physiol Regulatory Integrative Comp Physiol , vol.290 , pp. 114-123
    • De, F.1    Weiss, D.2    Carnell, P.H.3
  • 41
    • 0032566763 scopus 로고    scopus 로고
    • Quantum dot bioconjugates for ultrasensitive nonisotopic detection
    • Chan WC, Nie S. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science. 1998 ; 281: 2016-2018
    • (1998) Science , vol.281 , pp. 2016-2018
    • Chan, W.C.1    Nie, S.2
  • 42
    • 0041424802 scopus 로고    scopus 로고
    • Molecular profiling of single cells and tissue specimens with quantum dots
    • Gao X, Nie S. Molecular profiling of single cells and tissue specimens with quantum dots. Trends in Biotech. 2003 ; 21: 371-373
    • (2003) Trends in Biotech , vol.21 , pp. 371-373
    • Gao, X.1    Nie, S.2
  • 43
    • 0036469182 scopus 로고    scopus 로고
    • Luminescent quantum dots for multiplexed biological detection and imaging
    • Chan WC, Maxwell DJ, Gao X, et al. Luminescent quantum dots for multiplexed biological detection and imaging. Curr Op Biotech. 2002 ; 13: 40-46
    • (2002) Curr Op Biotech , vol.13 , pp. 40-46
    • Chan, W.C.1    Maxwell, D.J.2    Gao, X.3
  • 44
    • 0033009331 scopus 로고    scopus 로고
    • Immunological abnormalities. in primary APS evolving into SLE: 6 years follow-up in women with repeated. pregnancy loss
    • Carbone J, Oerra M, Rodriguez-Mahou M, et al. Immunological abnormalities. in primary APS evolving into SLE: 6 years follow-up in women with repeated. pregnancy loss. Lupus. 1999 ; 8: 274-278
    • (1999) Lupus , vol.8 , pp. 274-278
    • Carbone, J.1    Oerra, M.2    Rodriguez-Mahou, M.3
  • 45
    • 0036095703 scopus 로고    scopus 로고
    • Immunization of naïve Balb/c mice with human b2glycoprotein i breaks tolerance to the murine molecule
    • Tincani A, Gilburd B, Abu-Shakra M, et al. Immunization of naïve Balb/c mice with human b2glycoprotein I breaks tolerance to the murine molecule. Arthritis Rheum. 2002 ; 46: 1399-1404
    • (2002) Arthritis Rheum , vol.46 , pp. 1399-1404
    • Tincani, A.1    Gilburd, B.2    Abu-Shakra, M.3
  • 46
    • 67449159236 scopus 로고    scopus 로고
    • Complement activation in patients with primary antiphospholipid syndrome
    • Oku K, Atsumi T, Bohgaki M, et al. Complement activation in patients with primary antiphospholipid syndrome. Ann Rheum Dis. 2009 ; 68: 1030-1035
    • (2009) Ann Rheum Dis , vol.68 , pp. 1030-1035
    • Oku, K.1    Atsumi, T.2    Bohgaki, M.3
  • 47
    • 0034100612 scopus 로고    scopus 로고
    • Detection of complement-fixing antiphospholipid antibodies in association with thrombosis
    • Munakata Y, Saito T, Matsuda K, et al. Detection of complement-fixing antiphospholipid antibodies in association with thrombosis. Thromb Haemost. 2000 ; 83: 728-731
    • (2000) Thromb Haemost , vol.83 , pp. 728-731
    • Munakata, Y.1    Saito, T.2    Matsuda, K.3
  • 48
    • 0026706529 scopus 로고
    • Antiphospholipid antibodies and complement activation in patients with cerebral ischemia
    • Davis WD, Brey RL. Antiphospholipid antibodies and complement activation in patients with cerebral ischemia. Clin Exp Immunol. 1992 ; 10: 455-460
    • (1992) Clin Exp Immunol , vol.10 , pp. 455-460
    • Davis, W.D.1    Brey, R.L.2
  • 49
    • 0022545236 scopus 로고
    • Deposition of the terminal C5b-9 complement complex in infracted areas of human myocardium
    • Schafer H, Mathey D, Hugo F, Bhakdi S. Deposition of the terminal C5b-9 complement complex in infracted areas of human myocardium. J Immunol. 1986 ; 137: 1945-1949
    • (1986) J Immunol , vol.137 , pp. 1945-1949
    • Schafer, H.1    Mathey, D.2    Hugo, F.3    Bhakdi, S.4
  • 50
    • 17944384904 scopus 로고    scopus 로고
    • Sublytic concentrations of the membrane attack complex of complement induce interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activation
    • Kilgore KS, Schmid E, Shanley TP, et al. Sublytic concentrations of the membrane attack complex of complement induce interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activation. Am J Pathol. 1997 ; 150: 2019-2031
    • (1997) Am J Pathol , vol.150 , pp. 2019-2031
    • Kilgore, K.S.1    Schmid, E.2    Shanley, T.P.3
  • 51
    • 0023035428 scopus 로고
    • Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase
    • Wiedmer T, Esmon CT, Sims PJ. Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase. Blood. 1986 ; 68: 875-880
    • (1986) Blood , vol.68 , pp. 875-880
    • Wiedmer, T.1    Esmon, C.T.2    Sims, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.