메뉴 건너뛰기




Volumn 117, Issue 4, 2011, Pages 1408-1414

Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN E RECEPTOR 2; DIMER; IMMUNOGLOBULIN G; LIPOPROTEIN RECEPTOR; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 79251578627     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-07-299099     Document Type: Article
Times cited : (108)

References (47)
  • 1
    • 33344458573 scopus 로고    scopus 로고
    • International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    • Miyakis S, Lockshin MD, Atsumi T, et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006;4(2):295-306.
    • (2006) J Thromb Haemost , vol.4 , Issue.2 , pp. 295-306
    • Miyakis, S.1    Lockshin, M.D.2    Atsumi, T.3
  • 2
    • 0025951058 scopus 로고
    • Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin
    • Bevers EM, Galli M, Barbui T, Comfurius P, Zwaal RF. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemost. 1991;66(6):629-632.
    • (1991) Thromb Haemost , vol.66 , Issue.6 , pp. 629-632
    • Bevers, E.M.1    Galli, M.2    Barbui, T.3    Comfurius, P.4    Zwaal, R.F.5
  • 4
    • 0025302635 scopus 로고
    • Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
    • Galli M, Comfurius P, Maassen C, et al. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet. 1990;335(8705):1544-1547.
    • (1990) Lancet , vol.335 , Issue.8705 , pp. 1544-1547
    • Galli, M.1    Comfurius, P.2    Maassen, C.3
  • 5
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • DOI 10.1002/art.21009
    • Vega-Ostertag M, Casper K, Swerlick R, Ferrara D, Harris EN, Pierangeli SS. Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum. 2005;52(5):1545-1554. (Pubitemid 40663946)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.5 , pp. 1545-1554
    • Vega-Ostertag, M.1    Casper, K.2    Swerlick, R.3    Ferrara, D.4    Harris, E.N.5    Pierangeli, S.S.6
  • 6
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R, LaSala JM, Lo SK, et al. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest. 1995;96(5):2211-2219.
    • (1995) J Clin Invest , vol.96 , Issue.5 , pp. 2211-2219
    • Simantov, R.1    LaSala, J.M.2    Lo, S.K.3
  • 7
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • Pierangeli SS, Colden-Stanfield M, Liu X, Barker JH, Anderson GL, Harris EN. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation. 1999;99(15):1997-2002. (Pubitemid 29183897)
    • (1999) Circulation , vol.99 , Issue.15 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.3    Barker, J.H.4    Anderson, G.L.5    Harris, E.N.6
  • 8
    • 0030897237 scopus 로고    scopus 로고
    • Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation
    • Del Papa N, Guidali L, Sala A, et al. Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation. Arthritis Rheum. 1997;40(3):551-561.
    • (1997) Arthritis Rheum , vol.40 , Issue.3 , pp. 551-561
    • Del Papa, N.1    Guidali, L.2    Sala, A.3
  • 9
    • 34547733912 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
    • Sorice M, Longo A, Capozzi A, et al. Anti-beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum. 2007;56(8):2687-2697.
    • (2007) Arthritis Rheum , vol.56 , Issue.8 , pp. 2687-2697
    • Sorice, M.1    Longo, A.2    Capozzi, A.3
  • 10
    • 0141445991 scopus 로고    scopus 로고
    • 2-Glycoprotein I Increase Platelet Deposition to Collagen via Interaction with Phospholipids and the Apolipoprotein e Receptor 2′
    • DOI 10.1074/jbc.M212655200
    • Lutters BC, Derksen RH, Tekelenburg WL, Lenting PJ, Arnout J, de Groot PG. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2′. J Biol Chem. 2003;278(36):33831-33838. (Pubitemid 37553217)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 33831-33838
    • Lutters, B.C.H.1    Derksen, R.H.W.M.2    Tekelenburg, W.L.3    Lenting, P.J.4    Arnout, J.5    De, G.P.G.6
  • 11
  • 12
    • 0037217897 scopus 로고    scopus 로고
    • 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster
    • DOI 10.1182/blood-2002-05-1310
    • Jankowski M, Vreys I, Wittevrongel C, et al. Thrombogenicity of beta 2-glycoprotein I-dependent antiphospholipid antibodies in a photochemically induced thrombosis model in the hamster. Blood. 2003;101(1):157-162. (Pubitemid 36025902)
    • (2003) Blood , vol.101 , Issue.1 , pp. 157-162
    • Jankowski, M.1    Vreys, I.2    Wittevrongel, C.3    Boon, D.4    Vermylen, J.5    Hoylaerts, M.F.6    Arnout, J.7
  • 13
    • 14944367961 scopus 로고    scopus 로고
    • 2 glycoprotein I antibodies
    • DOI 10.1182/blood-2004-05-1708
    • Zhang J, McCrae KR. Annexin A2 mediates endothelial cell activation by antiphospholipid/anti-beta2 glycoprotein I antibodies. Blood. 2005;105(5):1964-1969. (Pubitemid 40731779)
    • (2005) Blood , vol.105 , Issue.5 , pp. 1964-1969
    • Zhang, J.1    McCrae, K.R.2
  • 14
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • Raschi E, Testoni C, Bosisio D, et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood. 2003;101(9):3495-3500.
    • (2003) Blood , vol.101 , Issue.9 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3
  • 15
    • 34250721890 scopus 로고    scopus 로고
    • Toll-like receptor and antiphospholipid mediated thrombosis: In vivo studies
    • Pierangeli SS, Vega-Ostertag ME, Raschi E, et al. Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies. Ann Rheum Dis. 2007;66(10):1327-1333.
    • (2007) Ann Rheum Dis , vol.66 , Issue.10 , pp. 1327-1333
    • Pierangeli, S.S.1    Vega-Ostertag, M.E.2    Raschi, E.3
  • 16
    • 33746593271 scopus 로고    scopus 로고
    • Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family
    • Pennings MT, van Lummel M, Derksen RH, et al. Interaction of beta2-glycoprotein I with members of the low density lipoprotein receptor family. J Thromb Haemost. 2006;4(8):1680-1690.
    • (2006) J Thromb Haemost , vol.4 , Issue.8 , pp. 1680-1690
    • Pennings, M.T.1    Van Lummel, M.2    Derksen, R.H.3
  • 17
    • 0032855538 scopus 로고    scopus 로고
    • Identification and characterization of LRP8 (apoER2) in human blood platelets
    • Riddell DR, Vinogradov DV, Stannard AK, Chadwick N, Owen JS. Identification and characterization of LRP8 (apoER2) in human blood platelets. J Lipid Res. 1999;40(10):1925-1930.
    • (1999) J Lipid Res , vol.40 , Issue.10 , pp. 1925-1930
    • Riddell, D.R.1    Vinogradov, D.V.2    Stannard, A.K.3    Chadwick, N.4    Owen, J.S.5
  • 18
    • 33747023522 scopus 로고    scopus 로고
    • Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V
    • Shi T, Giannakopoulos B, Yan X, et al. Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum. 2006;54(8):2558-2567.
    • (2006) Arthritis Rheum , vol.54 , Issue.8 , pp. 2558-2567
    • Shi, T.1    Giannakopoulos, B.2    Yan, X.3
  • 19
    • 33846443236 scopus 로고    scopus 로고
    • Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: Glycoprotein Ibalpha and apolipoprotein e receptor 2′
    • Pennings MT, Derksen RH, van Lummel M, et al. Platelet adhesion to dimeric beta-glycoprotein I under conditions of flow is mediated by at least two receptors: glycoprotein Ibalpha and apolipoprotein E receptor 2′. J Thromb Haemost. 2007;5(2):369-377.
    • (2007) J Thromb Haemost , vol.5 , Issue.2 , pp. 369-377
    • Pennings, M.T.1    Derksen, R.H.2    Van Lummel, M.3
  • 20
    • 47649130477 scopus 로고    scopus 로고
    • Platelet activation by dimeric beta2-glycoprotein I requires signaling via both glycoprotein Ibalpha and apolipoprotein e receptor 2′
    • Urbanus RT, Pennings MT, Derksen RH, de Groot PG. Platelet activation by dimeric beta2-glycoprotein I requires signaling via both glycoprotein Ibalpha and apolipoprotein E receptor 2′. J Thromb Haemost. 2008;6(8):1405-1412.
    • (2008) J Thromb Haemost , vol.6 , Issue.8 , pp. 1405-1412
    • Urbanus, R.T.1    Pennings, M.T.2    Derksen, R.H.3    De Groot, P.G.4
  • 21
    • 0037430967 scopus 로고    scopus 로고
    • Apolipoprotein e (apoE) isoforms differentially induce nitric oxide production in endothelial cells
    • Sacre SM, Stannard AK, Owen JS. Apolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cells. FEBS Lett. 2003;540(1-3):181-187.
    • (2003) FEBS Lett , vol.540 , Issue.1-3 , pp. 181-187
    • Sacre, S.M.1    Stannard, A.K.2    Owen, J.S.3
  • 22
    • 58549121206 scopus 로고    scopus 로고
    • Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells
    • Yang XV, Banerjee Y, Fernandez JA, et al. Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells. Proc Natl Acad Sci U S A. 2009;106(1):274-279.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.1 , pp. 274-279
    • Yang, X.V.1    Banerjee, Y.2    Fernandez, J.A.3
  • 23
    • 0035793644 scopus 로고    scopus 로고
    • Dimers of beta 2-glycoprotein I mimic the in vitro effects of beta 2-glycoprotein I-anti-beta 2-glycoprotein I antibody complexes
    • Lutters BC, Meijers JC, Derksen RH, Arnout J, de Groot PG. Dimers of beta 2-glycoprotein I mimic the in vitro effects of beta 2-glycoprotein I-anti-beta 2-glycoprotein I antibody complexes. J Biol Chem. 2001;276(5):3060-3067.
    • (2001) J Biol Chem , vol.276 , Issue.5 , pp. 3060-3067
    • Lutters, B.C.1    Meijers, J.C.2    Derksen, R.H.3    Arnout, J.4    De Groot, P.G.5
  • 25
    • 0031819709 scopus 로고    scopus 로고
    • Thrombogenic properties of antiphospholipid antibodies do not depend on their binding to beta2 glycoprotein 1 (beta2GP1) alone
    • Gharavi AE, Pierangeli SS, Gharavi EE, et al. Thrombogenic properties of antiphospholipid antibodies do not depend on their binding to beta2 glycoprotein 1 (beta2GP1) alone. Lupus. 1998;7(5):341-346.
    • (1998) Lupus , vol.7 , Issue.5 , pp. 341-346
    • Gharavi, A.E.1    Pierangeli, S.S.2    Gharavi, E.E.3
  • 26
    • 0025073323 scopus 로고
    • Antiphospholipid antibodies
    • Harris EN. Antiphospholipid antibodies. Br J Haematol. 1990;74(1):1-9.
    • (1990) Br J Haematol , vol.74 , Issue.1 , pp. 1-9
    • Harris, E.N.1
  • 27
    • 0346328425 scopus 로고    scopus 로고
    • Prevalence of antiphospholipid and antiplatelet antibodies in human immunodeficiency virus (HIV)-infected Chilean patients
    • Palomo I, Alarcon M, Sepulveda C, Pereira J, Espinola R, Pierangeli S. Prevalence of antiphospholipid and antiplatelet antibodies in human immunodeficiency virus (HIV)-infected Chilean patients. J Clin Lab Anal. 2003;17(6):209-215.
    • (2003) J Clin Lab Anal , vol.17 , Issue.6 , pp. 209-215
    • Palomo, I.1    Alarcon, M.2    Sepulveda, C.3    Pereira, J.4    Espinola, R.5    Pierangeli, S.6
  • 28
    • 0018135382 scopus 로고
    • A sensitive test demonstrating lupus anticoagulant and its behavioural patterns
    • Exner T, Rickard KA, Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavioural patterns. Br J Haematol. 1978;40(1):143-151.
    • (1978) Br J Haematol , vol.40 , Issue.1 , pp. 143-151
    • Exner, T.1    Rickard, K.A.2    Kronenberg, H.3
  • 29
    • 11144248088 scopus 로고    scopus 로고
    • Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall
    • Day SM, Reeve JL, Pedersen B, et al. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood. 2005;105(1):192-198.
    • (2005) Blood , vol.105 , Issue.1 , pp. 192-198
    • Day, S.M.1    Reeve, J.L.2    Pedersen, B.3
  • 30
    • 16644376635 scopus 로고    scopus 로고
    • Isolation and culture of murine macrophages
    • Davies JQ, Gordon S. Isolation and culture of murine macrophages. Methods Mol Biol. 2005;290:91-103.
    • (2005) Methods Mol Biol , vol.290 , pp. 91-103
    • Davies, J.Q.1    Gordon, S.2
  • 31
    • 0034006370 scopus 로고    scopus 로고
    • Cellular signalling by lipoprotein receptors
    • Herz J, Gotthardt M, Willnow TE. Cellular signalling by lipoprotein receptors. Curr Opin Lipidol. 2000;11(2):161-166.
    • (2000) Curr Opin Lipidol , vol.11 , Issue.2 , pp. 161-166
    • Herz, J.1    Gotthardt, M.2    Willnow, T.E.3
  • 32
    • 33644512817 scopus 로고    scopus 로고
    • Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein e receptor 2: Distinct roles in development and synaptic plasticity
    • Beffert U, Durudas A, Weeber EJ, et al. Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. J Neurosci. 2006;26(7):2041-2052.
    • (2006) J Neurosci , vol.26 , Issue.7 , pp. 2041-2052
    • Beffert, U.1    Durudas, A.2    Weeber, E.J.3
  • 34
    • 10644250612 scopus 로고    scopus 로고
    • Binding of low density lipoprotein to platelet apolipoprotein e receptor 2′ results in phosphorylation of p38MAPK
    • Korporaal SJ, Relou IA, van Eck M, et al. Binding of low density lipoprotein to platelet apolipoprotein E receptor 2′ results in phosphorylation of p38MAPK. J Biol Chem. 2004;279(50):52526-52534.
    • (2004) J Biol Chem , vol.279 , Issue.50 , pp. 52526-52534
    • Korporaal, S.J.1    Relou, I.A.2    Van Eck, M.3
  • 35
    • 35349013508 scopus 로고    scopus 로고
    • An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction
    • Shen GQ, Li L, Girelli D, et al. An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. Am J Hum Genet. 2007;81(4):780-791.
    • (2007) Am J Hum Genet , vol.81 , Issue.4 , pp. 780-791
    • Shen, G.Q.1    Li, L.2    Girelli, D.3
  • 37
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood. 2009;114(14):3074-3083.
    • (2009) Blood , vol.114 , Issue.14 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 38
    • 33846899419 scopus 로고    scopus 로고
    • The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies
    • Satta N, Dunoyer-Geindre S, Reber G, et al. The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies. Blood. 2007;109(4):1507-1514.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1507-1514
    • Satta, N.1    Dunoyer-Geindre, S.2    Reber, G.3
  • 40
    • 4444273214 scopus 로고    scopus 로고
    • Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin
    • Vega-Ostertag M, Harris EN, Pierangeli SS. Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. Arthritis Rheum. 2004;50(9):2911-2919.
    • (2004) Arthritis Rheum , vol.50 , Issue.9 , pp. 2911-2919
    • Vega-Ostertag, M.1    Harris, E.N.2    Pierangeli, S.S.3
  • 42
    • 0346969977 scopus 로고    scopus 로고
    • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
    • Girardi G, Berman J, Redecha P, et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest. 2003;112(11):1644-1654.
    • (2003) J Clin Invest , vol.112 , Issue.11 , pp. 1644-1654
    • Girardi, G.1    Berman, J.2    Redecha, P.3
  • 43
    • 34948903311 scopus 로고    scopus 로고
    • Tissue factor: A link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury
    • Redecha P, Tilley R, Tencati M, et al. Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood. 2007;110(7):2423-2431.
    • (2007) Blood , vol.110 , Issue.7 , pp. 2423-2431
    • Redecha, P.1    Tilley, R.2    Tencati, M.3
  • 44
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • DOI 10.1002/art.21157
    • Pierangeli SS, Girardi G, Vega-Ostertag M, Liu X, Espinola RG, Salmon J. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. A rthritis Rheum. 2005;52(7):2120-2124. (Pubitemid 40994335)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.7 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 45
    • 33744987414 scopus 로고    scopus 로고
    • Generation of C5a in the absence of C3: A new complement activation pathway
    • Huber-Lang M, Sarma JV, Zetoune FS, et al. Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med. 2006;12(6):682-687.
    • (2006) Nat Med , vol.12 , Issue.6 , pp. 682-687
    • Huber-Lang, M.1    Sarma, J.V.2    Zetoune, F.S.3
  • 46
    • 27144494245 scopus 로고    scopus 로고
    • Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor
    • Fischetti F, Durigutto P, Pellis V, et al. Thrombus formation induced by antibodies to beta2-glycoprotein I is complement dependent and requires a priming factor. Blood. 2005;106(7):2340-2346.
    • (2005) Blood , vol.106 , Issue.7 , pp. 2340-2346
    • Fischetti, F.1    Durigutto, P.2    Pellis, V.3
  • 47
    • 33344456904 scopus 로고    scopus 로고
    • Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change
    • de Laat B, Derksen RH, van Lummel M, Pennings MT, de Groot PG. Pathogenic anti-beta2-glycoprotein I antibodies recognize domain I of beta2-glycoprotein I only after a conformational change. Blood. 2006;107(5):1916-1924.
    • (2006) Blood , vol.107 , Issue.5 , pp. 1916-1924
    • De Laat, B.1    Derksen, R.H.2    Van Lummel, M.3    Pennings, M.T.4    De Groot, P.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.