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Volumn 119, Issue 3, 2012, Pages 884-893

A novel pathway for human endothelial cell activation by antiphospholipid/anti-β2 glycoprotein I antibodies

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; CALRETICULIN; LIPOCORTIN 2; NUCLEOLIN; TOLL LIKE RECEPTOR 4;

EID: 84862909113     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-03-344671     Document Type: Article
Times cited : (122)

References (50)
  • 1
    • 0038315452 scopus 로고    scopus 로고
    • The Antiphospholipid Syndrome
    • DOI 10.1146/annurev.med.54.101601.152412
    • Rand JH. The antiphospholipid syndrome. Ann Rev Med. 2003;54:409-424. (Pubitemid 37386404)
    • (2003) Annual Review of Medicine , vol.54 , pp. 409-424
    • Rand, J.H.1
  • 3
    • 50249189294 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome: Pathogenic mechanisms
    • Pierangeli SS, Chen PP, Raschi E, et al. Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms. Semin Thromb Hemost. 2008;34(3):236-250.
    • (2008) Semin Thromb Hemost , vol.34 , Issue.3 , pp. 236-250
    • Pierangeli, S.S.1    Chen, P.P.2    Raschi, E.3
  • 4
    • 67649371944 scopus 로고    scopus 로고
    • Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: A multicentre prospective study of 1000 patients
    • Cervera R, Khamashta MA, Shoenfeld Y, et al. Morbidity and mortality in the antiphospholipid syndrome during a 5-year period: a multicentre prospective study of 1000 patients. Ann Rheum Dis. 2009;68:1428-1432.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1428-1432
    • Cervera, R.1    Khamashta, M.A.2    Shoenfeld, Y.3
  • 5
    • 0025332717 scopus 로고
    • Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: Beta 2-glycoprotein I (apolipoprotein H)
    • McNeil HP, Simpson RJ, Chesterman CN, Krilis SA. Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci U S A. 1990;87(11):4120-4125.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.11 , pp. 4120-4125
    • McNeil, H.P.1    Simpson, R.J.2    Chesterman, C.N.3    Krilis, S.A.4
  • 6
    • 0026817042 scopus 로고
    • A phospholipid-beta2-glycoprotein complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection
    • Hunt JE, McNeil HP, Morgan GJ, Crameri RM, Krilis SA. A phospholipid-beta2-glycoprotein complex is an antigen for anticardiolipin antibodies occurring in autoimmune disease but not with infection. Lupus. 1992;1(2):75-81.
    • (1992) Lupus , vol.1 , Issue.2 , pp. 75-81
    • Hunt, J.E.1    McNeil, H.P.2    Morgan, G.J.3    Crameri, R.M.4    Krilis, S.A.5
  • 7
    • 70449390005 scopus 로고    scopus 로고
    • The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: An international multicenter study
    • de Laat B, Pengo V, Pabinger I, et al. The association between circulating antibodies against domain I of beta2-glycoprotein I and thrombosis: an international multicenter study. J Thromb Haemost. 2009;7(11):1767-1773.
    • (2009) J Thromb Haemost , vol.7 , Issue.11 , pp. 1767-1773
    • De Laat, B.1    Pengo, V.2    Pabinger, I.3
  • 8
    • 79953083750 scopus 로고    scopus 로고
    • Beta2 glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model
    • Arad A, Proulle V, Furie RA, Furie BC, Furie B. Beta2 glycoprotein-1 autoantibodies from patients with antiphospholipid syndrome are sufficient to potentiate arterial thrombus formation in a mouse model. Blood. 2011;117(24):3453-3459.
    • (2011) Blood , vol.117 , Issue.24 , pp. 3453-3459
    • Arad, A.1    Proulle, V.2    Furie, R.A.3    Furie, B.C.4    Furie, B.5
  • 9
    • 33846243719 scopus 로고    scopus 로고
    • Current concepts on the pathogenesis of the antiphospholipid syndrome
    • Giannakopoulos B, Passam F, Rahgozar S, Krilis SA. Current concepts on the pathogenesis of the antiphospholipid syndrome. Blood. 2007; 109(2):422-429.
    • (2007) Blood , vol.109 , Issue.2 , pp. 422-429
    • Giannakopoulos, B.1    Passam, F.2    Rahgozar, S.3    Krilis, S.A.4
  • 10
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R, LaSala JM, Lo SK, et al. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest. 1995;96(5): 2211-2219.
    • (1995) J Clin Invest , vol.96 , Issue.5 , pp. 2211-2219
    • Simantov, R.1    LaSala, J.M.2    Lo, S.K.3
  • 11
    • 14944367961 scopus 로고    scopus 로고
    • 2 glycoprotein I antibodies
    • DOI 10.1182/blood-2004-05-1708
    • Zhang J, McCrae KR. Annexin II mediates endothelial cell activation by antiphospholipid/antibeta2-glycoprotein I antibodies. Blood. 2005; 105(5):1964-1969. (Pubitemid 40731779)
    • (2005) Blood , vol.105 , Issue.5 , pp. 1964-1969
    • Zhang, J.1    McCrae, K.R.2
  • 12
    • 0030897237 scopus 로고    scopus 로고
    • Endothelial cells as targets for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation
    • Del Papa N, Guidala L, Sala A, et al. Endothelial cells as targets for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation. Arthritis Rheum. 1997;40(3):551-561.
    • (1997) Arthritis Rheum , vol.40 , Issue.3 , pp. 551-561
    • Del Papa, N.1    Guidala, L.2    Sala, A.3
  • 14
    • 70449509134 scopus 로고    scopus 로고
    • Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo
    • Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood. 2009;114(14): 3074-3083.
    • (2009) Blood , vol.114 , Issue.14 , pp. 3074-3083
    • Romay-Penabad, Z.1    Montiel-Manzano, M.G.2    Shilagard, T.3
  • 15
    • 0028173807 scopus 로고
    • Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice
    • Pierangeli SS, Barker JH, Stikovac D, et al. Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice. Thromb Haemost. 1994;71(5):670-674.
    • (1994) Thromb Haemost , vol.71 , Issue.5 , pp. 670-674
    • Pierangeli, S.S.1    Barker, J.H.2    Stikovac, D.3
  • 16
    • 0035793334 scopus 로고    scopus 로고
    • Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin
    • Pierangeli SS, Espinola RG, Liu X, Harris EN. Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and P-Selectin. Circ Res. 2001;88(2):245-250. (Pubitemid 32147315)
    • (2001) Circulation Research , vol.88 , Issue.2 , pp. 245-250
    • Pierangeli, S.S.1    Espinola, R.G.2    Liu, X.3    Harris, E.N.4
  • 19
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • DOI 10.1182/blood-2002-08-2349
    • Raschi E, Testoni D, Dosisio D, et al. Role of the MyD88 transduction signaling pathway in endothelial cell activation by antiphospholipid antibodies. Blood. 2003;101(9):3495-3500. (Pubitemid 36857933)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3    Borghi, M.O.4    Koike, T.5    Mantovani, A.6    Meroni, P.L.7
  • 20
    • 0029939928 scopus 로고    scopus 로고
    • Monoclonal antibodies from NZW x BXSB F1 mice to beta2 glycoprotein I and cardiolipin. Species specificity and charge-dependent binding
    • Monestier M, Kandiah DA, Kouts S, et al. Monoclonal antibodies from NZW x BXSB F1 mice to beta2 glycoprotein I and cardiolipin. Species specificity and charge-dependent binding. J Immunol. 1996;156(7):2631-2641.
    • (1996) J Immunol , vol.156 , Issue.7 , pp. 2631-2641
    • Monestier, M.1    Kandiah, D.A.2    Kouts, S.3
  • 21
    • 78650961942 scopus 로고    scopus 로고
    • Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via beta2GPI and apoER2
    • Ramesh S, Morrell CN, Tarango C, et al. Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via beta2GPI and apoER2. J Clin Invest. 2011;121(1):120-131.
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 120-131
    • Ramesh, S.1    Morrell, C.N.2    Tarango, C.3
  • 22
    • 79959441187 scopus 로고    scopus 로고
    • Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors
    • Allen KL, Hamik A, Jain MK, McCrae KR. Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors. Blood. 2011;117(23):6383-6391.
    • (2011) Blood , vol.117 , Issue.23 , pp. 6383-6391
    • Allen, K.L.1    Hamik, A.2    Jain, M.K.3    McCrae, K.R.4
  • 24
    • 79956312573 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates the activation of human monocytes and endothelial cells by antiphospholipid antibodies
    • Satta N, Kruithof EK, Fickentscher C, et al. Toll-like receptor 2 mediates the activation of human monocytes and endothelial cells by antiphospholipid antibodies. Blood. 2011;117(20):5523-5531.
    • (2011) Blood , vol.117 , Issue.20 , pp. 5523-5531
    • Satta, N.1    Kruithof, E.K.2    Fickentscher, C.3
  • 25
    • 77951213979 scopus 로고    scopus 로고
    • The role of LRP8 (ApoER2′) in the pathophysiology of the antiphospholipid syndrome
    • de Groot PG, Derksen RH, Urbanus RT. The role of LRP8 (ApoER2′) in the pathophysiology of the antiphospholipid syndrome. Lupus. 2010;19(4): 389-393.
    • (2010) Lupus , vol.19 , Issue.4 , pp. 389-393
    • De Groot, P.G.1    Derksen, R.H.2    Urbanus, R.T.3
  • 26
    • 79251578627 scopus 로고    scopus 로고
    • Apolipoprotein e receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome
    • Romay-Penabad Z, Aguilar-Valenzuela R, Urbanus RT, et al. Apolipoprotein E receptor 2 is involved in the thrombotic complications in a murine model of the antiphospholipid syndrome. Blood. 2011;117(4):1408-1414.
    • (2011) Blood , vol.117 , Issue.4 , pp. 1408-1414
    • Romay-Penabad, Z.1    Aguilar-Valenzuela, R.2    Urbanus, R.T.3
  • 27
    • 0344304541 scopus 로고    scopus 로고
    • Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
    • DOI 10.1083/jcb.200304132
    • Christian S, Pilch J, Akerman ME, Porkka K, Laakkonen P, Ruoslahti E. Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels. J Cell Biol. 2003; 163(4):871-878. (Pubitemid 37517893)
    • (2003) Journal of Cell Biology , vol.163 , Issue.4 , pp. 871-878
    • Christian, S.1    Pilch, J.2    Akerman, M.E.3    Porkka, K.4    Laakkonen, P.5    Ruoslahti, E.6
  • 28
    • 35548988483 scopus 로고    scopus 로고
    • Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin
    • DOI 10.1182/blood-2007-01-064428
    • Shi H, Huang Y, Zhou H, et al. Nucleolin is a receptor that mediates antiangiogenic and antitumor activity of endostatin. Blood. 2007;110(8): 2899-2906. (Pubitemid 350006943)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2899-2906
    • Shi, H.1    Huang, Y.2    Zhou, H.3    Song, X.4    Yuan, S.5    Fu, Y.6    Luo, Y.7
  • 29
    • 33744955154 scopus 로고    scopus 로고
    • Up-regulation of the KLF2 transcription factor by fluid shear stress requires nucleolin
    • DOI 10.1074/jbc.M513406200
    • Huddleson JP, Ahmad N, Lingrel JB. Up-regulation of the KLF2 transcription factor by fluid shear stress requires nucleolin. J Biol Chem. 2006;281(22): 15121-15128. (Pubitemid 43855101)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.22 , pp. 15121-15128
    • Huddleson, J.P.1    Ahmad, N.2    Lingrel, J.B.3
  • 30
    • 77957682653 scopus 로고    scopus 로고
    • Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells
    • Tarr JM, Winyard PG, Ryan B, et al. Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells. Arthritis Rheum. 2010;62(10):2919-2929.
    • (2010) Arthritis Rheum , vol.62 , Issue.10 , pp. 2919-2929
    • Tarr, J.M.1    Winyard, P.G.2    Ryan, B.3
  • 31
    • 0038756766 scopus 로고    scopus 로고
    • Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule
    • DOI 10.1074/jbc.M302306200
    • Ghiran I, Klickstein LB, Nicholson-Weller A. Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule. J Biol Chem. 2003;278(23):21024-21031. (Pubitemid 36806413)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.23 , pp. 21024-21031
    • Ghiran, I.1    Klickstein, L.B.2    Nicholson-Weller, A.3
  • 34
    • 0038491346 scopus 로고    scopus 로고
    • Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits
    • MacLeod TJ, Kwon M, Filipenko NR, Waisman DA. Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits. J Biol Chem. 2003;278: 25577-25584.
    • (2003) J Biol Chem , vol.278 , pp. 25577-25584
    • MacLeod, T.J.1    Kwon, M.2    Filipenko, N.R.3    Waisman, D.A.4
  • 35
    • 6344241866 scopus 로고    scopus 로고
    • An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface
    • DOI 10.1074/jbc.M408078200
    • Deora AB, Kreitzer G, Jacovina AT, Hajjar KA. An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface. J Biol Chem. 2004;279(42):43411-43418. (Pubitemid 39390640)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.42 , pp. 43411-43418
    • Deora, A.B.1    Kreitzer, G.2    Jacovina, A.T.3    Hajjar, K.A.4
  • 38
    • 74849118341 scopus 로고    scopus 로고
    • Lipid rafts as a membrane-organizing principle
    • Lingwood D, Simons K. Lipid rafts as a membrane-organizing principle. Science. 2010; 327(5961):46-50.
    • (2010) Science , vol.327 , Issue.5961 , pp. 46-50
    • Lingwood, D.1    Simons, K.2
  • 39
    • 34547733912 scopus 로고    scopus 로고
    • 2-Glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
    • 2-Glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum. 2007;56(8):2687-2697.
    • (2007) Arthritis Rheum , vol.56 , Issue.8 , pp. 2687-2697
    • Sorice, M.1    Longo, A.2    Capozzi, A.3
  • 40
    • 79955382971 scopus 로고    scopus 로고
    • Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2
    • He KL, Sui G, Xiong H, et al. Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2. J Biol Chem. 2011;286(17):15428-15439.
    • (2011) J Biol Chem , vol.286 , Issue.17 , pp. 15428-15439
    • He, K.L.1    Sui, G.2    Xiong, H.3
  • 41
    • 32344449064 scopus 로고    scopus 로고
    • Ligand-independent oligomerization of TLR4 regulated by a short hydrophobic region adjacent to the transmembrane domain
    • DOI 10.1016/j.bbrc.2006.01.074, PII S0006291X06001495
    • Nishiya T, Kajita E, Miwa S. Ligand-independent oligomerization of TLR4 regulated by a short hydrophobic region adjacent to the transmembrane domain. Biochem Biophys Res Commun. 2006; 341(4):1128-1134. (Pubitemid 43221782)
    • (2006) Biochemical and Biophysical Research Communications , vol.341 , Issue.4 , pp. 1128-1134
    • Nishiya, T.1    Kajita, E.2    Miwa, S.3
  • 42
    • 79959536183 scopus 로고    scopus 로고
    • The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation
    • Panter G, Jerala R. The ectodomain of the Toll-like receptor 4 prevents constitutive receptor activation. J Biol Chem. 2011;286(26):23334-23344.
    • (2011) J Biol Chem , vol.286 , Issue.26 , pp. 23334-23344
    • Panter, G.1    Jerala, R.2
  • 43
    • 37449018934 scopus 로고    scopus 로고
    • Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization
    • Youn HS, Lee JK, Choi YJ, et al. Cinnamaldehyde suppresses toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization. Biochem Pharmacol. 2008;75(2): 494-502.
    • (2008) Biochem Pharmacol , vol.75 , Issue.2 , pp. 494-502
    • Youn, H.S.1    Lee, J.K.2    Choi, Y.J.3
  • 45
    • 77956225959 scopus 로고    scopus 로고
    • Expression and regulation of toll-like receptors in cerebral endothelial cells
    • Nagyoszi P, Wilhelm I, Farkas AE, et al. Expression and regulation of toll-like receptors in cerebral endothelial cells. Neurochem Int. 2010;57(5): 556-564.
    • (2010) Neurochem Int , vol.57 , Issue.5 , pp. 556-564
    • Nagyoszi, P.1    Wilhelm, I.2    Farkas, A.E.3
  • 46
    • 0141445991 scopus 로고    scopus 로고
    • 2-Glycoprotein I Increase Platelet Deposition to Collagen via Interaction with Phospholipids and the Apolipoprotein E Receptor 2′
    • DOI 10.1074/jbc.M212655200
    • Lutters BC, Derksen RH, Tekelenburg WL, Lenting PJ, Arnout J, De Groot PG. Dimers of beta 2-glycoprotein I increase platelet deposition to collagen via interaction with phospholipids and the apolipoprotein E receptor 2′. J Biol Chem. 2003;278(36):33831-33838. (Pubitemid 37553217)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 33831-33838
    • Lutters, B.C.H.1    Derksen, R.H.W.M.2    Tekelenburg, W.L.3    Lenting, P.J.4    Arnout, J.5    De Groot, P.G.6
  • 47
    • 0037020093 scopus 로고    scopus 로고
    • The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin
    • Goicoechea S, Pallero MA, Eggleton P, Michalak M, Murphy-Ullrich JE. The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin. J Biol Chem. 2002; 277(40):37219-37228.
    • (2002) J Biol Chem , vol.277 , Issue.40 , pp. 37219-37228
    • Goicoechea, S.1    Pallero, M.A.2    Eggleton, P.3    Michalak, M.4    Murphy-Ullrich, J.E.5
  • 48
    • 0036498603 scopus 로고    scopus 로고
    • Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading
    • Feng X, Tonnesen MG, Peerschke EI, Ghebrehiwet B. Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading. J Immunol. 2002; 168(5):2441-2448. (Pubitemid 34171848)
    • (2002) Journal of Immunology , vol.168 , Issue.5 , pp. 2441-2448
    • Feng, X.1    Tonnesen, M.G.2    Peerschke, E.I.B.3    Ghebrehiwet, B.4
  • 49
    • 67149121074 scopus 로고    scopus 로고
    • TLR4/MyD88/PI3K interactions regulate TLR4 signaling
    • Laird MH, Rhee SH, Perkins DJ, et al. TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J Leukoc Biol. 2009;85(6):966-977.
    • (2009) J Leukoc Biol , vol.85 , Issue.6 , pp. 966-977
    • Laird, M.H.1    Rhee, S.H.2    Perkins, D.J.3
  • 50
    • 77958183207 scopus 로고    scopus 로고
    • Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome
    • Ortona E, Capozzi A, Colasanti T, et al. Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome. Blood. 2010; 116(16):2960-2967.
    • (2010) Blood , vol.116 , Issue.16 , pp. 2960-2967
    • Ortona, E.1    Capozzi, A.2    Colasanti, T.3


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