Deep Phosphotyrosine Proteomics by Optimization of Phosphotyrosine Enrichment and MS/MS Parameters

Journal of Proteome Research

Volumn 16, Issue 2, 2017, Pages 1077-1086

  Abe, Yuichi ^a   Nagano, Maiko ^a   Tada, Asa ^a   Adachi, Jun ^a   Tomonaga, Takeshi ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

cancer; immunoprecipitation; kinome; phosphorylation signaling; phosphotyrosine

Indexed keywords

ERLOTINIB; PHOSPHOTYROSINE; PROTEIN HYDROLYSATE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; ANTINEOPLASTIC AGENT; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 13; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PTK6 PROTEIN, HUMAN; TUMOR PROTEIN; TYROSINE;

ARTICLE; CONTROLLED STUDY; DATA BASE; ENZYME ACTIVE SITE; HCT 116 CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEOMICS; REPRODUCIBILITY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIQUID CHROMATOGRAPHY; METABOLISM; PHOSPHORYLATION; PROCEDURES; PROTEIN DATABASE; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DATABASES, PROTEIN; ERLOTINIB HYDROCHLORIDE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; MITOGEN-ACTIVATED PROTEIN KINASE 13; NEOPLASM PROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-TYROSINE KINASES; PROTEOMICS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TYROSINE;

EID: 85011664736     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.6b00576     Document Type: Article

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