BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis

eLife

Volumn 6, Issue , 2017, Pages

  Sakamoto, Naoya ^a,b   Feng, Ying ^a   Stolfi, Carmine ^a   Kurosu, Yuki ^a   Green, Maranne ^a   Lin, Jeffry ^a   Green, Megan E ^a   Sentani, Kazuhiro ^b   Yasui, Wataru ^b   McMahon, Martin ^c,d   Hardiman, Karin M ^a   Spence, Jason R ^a,e   Horita, Nobukatsu ^e   Greenson, Joel K ^a   Kuick, Rork ^e   Cho, Kathleen R ^a   Fearon, Eric R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b HIROSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; TAMOXIFEN; TRANSCRIPTION FACTOR CDX2; BRAF PROTEIN, HUMAN; BRAF PROTEIN, MOUSE; CDX2 PROTEIN, HUMAN; CDX2 PROTEIN, MOUSE;

ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; COLORECTAL TUMOR; CONTROLLED STUDY; CPG ISLAND; DIGESTIVE SYSTEM CANCER; DNA METHYLATION; DOWN REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROSATELLITE MARKER; MOUSE; NONHUMAN; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; COLON; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETICS; INTESTINE MUCOSA; METABOLISM; ORGANOID; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; CARCINOGENESIS; CDX2 TRANSCRIPTION FACTOR; COLON; COLORECTAL NEOPLASMS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; INTESTINAL MUCOSA; MICE; ORGANOIDS; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 85011035037     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.20331     Document Type: Article

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