Sox9 induction, ectopic paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation

American Journal of Pathology

Volumn 183, Issue 2, 2013, Pages 493-503

  Feng, Ying ^a   Sentani, Kazuhiro ^a   Wiese, Alexandra ^a   Sands, Evan ^a   Green, Maranne ^a   Bommer, Guido T ^a,b   Cho, Kathleen R ^a   Fearon, Eric R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b DE DUVE INSTITUTE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; CELL MARKER; CRE RECOMBINASE; LGR5 PROTEIN; MUSASHI 1 PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL BUDDING; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURFACE; CELL TYPE; COLON ADENOMA; COLON MUCOSA; CONTROLLED STUDY; CRYPT CELL; ENZYME ACTIVITY; GENE CONTROL; GENE INACTIVATION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE EPITHELIUM; MALE; MITOSIS SPINDLE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PANETH CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; RECTUM; SINGLE DRUG DOSE; SMALL INTESTINE; STEM CELL; STEM CELL NICHE; TRANSGENIC ANIMAL; TUMOR CELL; TUMOR SUPPRESSOR GENE;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; GENE SILENCING; GENES, APC; HOMEODOMAIN PROTEINS; HUMANS; INTESTINAL MUCOSA; MICE; MICE, TRANSGENIC; MITOTIC SPINDLE APPARATUS; PANETH CELLS; SOX9 TRANSCRIPTION FACTOR; TAMOXIFEN; TRANSCRIPTION FACTORS; TRANSGENES;

EID: 84880588395     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.04.013     Document Type: Article

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