A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 4, 2017, Pages E570-E579

  Saxena, Kapil ^a   Simon, Lukas M ^a,c   Zeng, Xi Lei ^a   Blutt, Sarah E ^a   Crawford, Sue E ^a   Sastri, Narayan P ^a   Karandikar, Umesh C ^a   Ajami, Nadim J ^a   Zachos, Nicholas C ^b   Kovbasnjuk, Olga ^b   Donowitz, Mark ^b   Conner, Margaret E ^a   Shaw, Chad A ^a   Estes, Mary K ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Enteric virus; Human enteroids; Human rotavirus; Interferon

Indexed keywords

ALPHA INTERFERON; ALPHA2 INTERFERON; BETA INTERFERON; BETA1 INTERFERON; GAMMA INTERFERON; INTERFERON LAMBDA 3; INTERLEUKIN 28A; INTERLEUKIN 29; INTERLEUKIN 8; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 3; POLYINOSINIC POLYCYTIDYLIC ACID; UNCLASSIFIED DRUG; INTERFERON;

ANIMAL TISSUE; CONFERENCE PAPER; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN ROTAVIRUS; HUMAN TISSUE; INNATE IMMUNITY; INTESTINAL ENTEROID; INTESTINE EPITHELIUM; INTESTINE INFECTION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; RNA TRANSLATION; ROTAVIRUS INFECTION; SIGNAL TRANSDUCTION; UPREGULATION; VIROGENESIS; VIRUS REPLICATION; ANIMAL; CELL LINE; CHLOROCEBUS AETHIOPS; GENETICS; IMMUNOLOGY; PHYSIOLOGY; ROTAVIRUS; SEQUENCE ANALYSIS; SMALL INTESTINE;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; HUMANS; IMMUNITY, INNATE; INTERFERONS; INTESTINE, SMALL; ROTAVIRUS; ROTAVIRUS INFECTIONS; SEQUENCE ANALYSIS, RNA; VIRUS REPLICATION;

EID: 85010953404     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1615422114     Document Type: Article

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