Comparative Proteomics Reveals Strain-Specific β-TrCP Degradation via Rotavirus NSP1 Hijacking a Host Cullin-3-Rbx1 Complex

PLoS Pathogens

Volumn 12, Issue 10, 2016, Pages

  Ding, Siyuan ^a,b   Mooney, Nancie ^a   Li, Bin ^a,b,c   Kelly, Marcus R ^a   Feng, Ningguo ^a,b   Loktev, Alexander V ^a   Sen, Adrish ^a,b   Patton, John T ^d   Jackson, Peter K ^a   Greenberg, Harry B ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CULLIN; CULLIN 3; NONSTRUCTURAL PROTEIN 1; PEPTIDES AND PROTEINS; RING BOX PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRAL PROTEIN; CARRIER PROTEIN; CUL3 PROTEIN, HUMAN; NSP1 PROTEIN, ROTAVIRUS; RBX1 PROTEIN, HUMAN;

ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; ENZYME SUBSTRATE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; INTESTINE CELL; LIQUID CHROMATOGRAPHY; LUCIFERASE ASSAY; MASS SPECTROMETRY; PLAQUE ASSAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; ROTAVIRUS; VIRUS CELL INTERACTION; WESTERN BLOTTING; ANIMAL; COMPARATIVE STUDY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; HEK293 CELL LINE; HOST PARASITE INTERACTION; METABOLISM; PHYSIOLOGY; PROCEDURES; ROTAVIRUS INFECTION;

ANIMALS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; BLOTTING, WESTERN; CARRIER PROTEINS; CULLIN PROTEINS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEK293 CELLS; HOST-PARASITE INTERACTIONS; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; ROTAVIRUS INFECTIONS; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84992708826     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005929     Document Type: Article

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