Comparative proteomic analysis of 2-MCPD- and 3-MCPD-induced heart toxicity in the rat

Archives of Toxicology

Volumn 91, Issue 9, 2017, Pages 3145-3155

  Schultrich, Katharina ^a   Frenzel, Falko ^a   Oberemm, Axel ^a   Buhrke, Thorsten ^a   Braeuning, Albert ^a   Lampen, Alfonso ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Cardiotoxicity; Heat induced food contaminant; MCPD esters; Monochloropropanediol

Indexed keywords

2 MONOCHLOROPROPANEDIOL; 3 MONOCHLOROPROPANEDIOL; ACETYL COENZYME A ACETYLTRANSFERASE MITOCHONDRIA; ACTIN; ARGINASE 1; CARBONATE DEHYDRATASE III; ESTER; EUKARYOTIC TRANSLATION INITION FACTOR 3 SUBUNIT I; FATTY ACID ESTER; GLUTATHIONE TRANSFERASE M1; GUANINE DEAMINASE; HEAT SHOCK PROTEIN 90 ALPHA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROHETEROGENEOUS K; LIPOCORTIN 1; MACROPHAGE CAPPING PROTEIN; PROPANEDIOL DERIVATIVE; PROTEIN; PROTEIN DEGLYCASE DJ-1; SERPIN H1; TRIPARTITE MOTIF CONTAINING PROTEIN 72; TROPOMYOSIN; TROPONIN T; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; WD REPEAT CONTAINING PROTEIN 1; 2-MONOCHLOROPROPANEDIOL; ALPHA CHLOROHYDRIN; GLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CELL INFILTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; IMMUNOREACTIVITY; INFLAMMATORY CELL; MALE; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEOMICS; RAT; RISK ASSESSMENT; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; METABOLISM; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ALPHA-CHLOROHYDRIN; ANIMALS; CARDIOTOXICITY; GLYCEROL; MALE; PROTEINS; PROTEOMICS; RATS, WISTAR;

EID: 85010952220     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-016-1927-0     Document Type: Article

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