Relative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in rats

Archives of Toxicology

Volumn 87, Issue 4, 2013, Pages 649-659

  Abraham, Klaus ^a   Appel, Klaus E ^a   Berger Preiss, Edith ^b   Apel, Elisabeth ^b   Gerling, Susanne ^b   Mielke, Hans ^a   Creutzenberg, Otto ^b   Lampen, Alfonso ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

3 MCPD fatty acid ester; Bioavailability; Enzymatic hydrolysis; Risk assessment; Toxicokinetics

Indexed keywords

1,2 DIPALMITOYL 3 CHLOROPROPANE 1,2 DIOL; ALPHA CHLOROHYDRIN; FATTY ACID ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; CONTROLLED STUDY; FECES LEVEL; FOOD CONTAMINATION; GASTROINTESTINAL TRACT; HYDROLYSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; TISSUE DISTRIBUTION; TISSUE LEVEL; TOXICOKINETICS; URINE LEVEL;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CARCINOGENS; ESTERS; FATTY ACIDS; FOOD CONTAMINATION; GASTROINTESTINAL CONTENTS; GLYCEROL; HYDROLYSIS; MALE; RATS; RATS, WISTAR; RISK ASSESSMENT;

RATTUS;

EID: 84876677612     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0970-8     Document Type: Article

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