-
1
-
-
67649958842
-
Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management
-
COI: 1:CAS:528:DC%2BD1MXoslajsrg%3D, PID: 19520246
-
Yeh ET, Bickford CL. Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management. J Am Coll Cardiol. 2009;53:2231–47.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 2231-2247
-
-
Yeh, E.T.1
Bickford, C.L.2
-
2
-
-
84922946917
-
Protein quality control and metabolism: bidirectional control in the heart
-
COI: 1:CAS:528:DC%2BC2MXhsFals74%3D, PID: 25651176
-
Wang ZV, Hill JA. Protein quality control and metabolism: bidirectional control in the heart. Cell Metab. 2015;21:215–26.
-
(2015)
Cell Metab
, vol.21
, pp. 215-226
-
-
Wang, Z.V.1
Hill, J.A.2
-
3
-
-
77955173081
-
Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload
-
COI: 1:CAS:528:DC%2BC3cXpsVWksr0%3D, PID: 20625112
-
Fu HY, Okada K, Liao Y, et al. Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload. Circulation. 2010;122:361–9.
-
(2010)
Circulation
, vol.122
, pp. 361-369
-
-
Fu, H.Y.1
Okada, K.2
Liao, Y.3
-
4
-
-
34948866189
-
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome
-
PID: 17709641
-
Myoishi M, Hao H, Minamino T, et al. Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome. Circulation. 2007;116:1226–33.
-
(2007)
Circulation
, vol.116
, pp. 1226-1233
-
-
Myoishi, M.1
Hao, H.2
Minamino, T.3
-
5
-
-
30544446127
-
Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice
-
COI: 1:CAS:528:DC%2BD28XmsVClsQ%3D%3D, PID: 16403436
-
Tsukamoto O, Minamino T, Okada K, et al. Depression of proteasome activities during the progression of cardiac dysfunction in pressure-overloaded heart of mice. Biochem Biophys Res Commun. 2006;340:1125–33.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 1125-1133
-
-
Tsukamoto, O.1
Minamino, T.2
Okada, K.3
-
6
-
-
78349265743
-
Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
-
COI: 1:CAS:528:DC%2BC3cXhtlGjsrrI, PID: 21030724
-
Minamino T, Komuro I, Kitakaze M. Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res. 2010;107:1071–82.
-
(2010)
Circ Res
, vol.107
, pp. 1071-1082
-
-
Minamino, T.1
Komuro, I.2
Kitakaze, M.3
-
7
-
-
52449095380
-
Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition
-
COI: 1:CAS:528:DC%2BD1cXhtFChsr7O, PID: 18508854
-
Fu HY, Minamino T, Tsukamoto O, et al. Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition. Cardiovasc Res. 2008;79:600–10.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 600-610
-
-
Fu, H.Y.1
Minamino, T.2
Tsukamoto, O.3
-
8
-
-
84956963882
-
Chemical endoplasmic reticulum chaperone alleviates doxorubicin-induced cardiac dysfunction
-
COI: 1:CAS:528:DC%2BC28Xjs1Sqsr0%3D, PID: 26838784
-
Fu HY, Sanada S, Matsuzaki T, et al. Chemical endoplasmic reticulum chaperone alleviates doxorubicin-induced cardiac dysfunction. Circ Res. 2016;118:798–809.
-
(2016)
Circ Res
, vol.118
, pp. 798-809
-
-
Fu, H.Y.1
Sanada, S.2
Matsuzaki, T.3
-
9
-
-
84976889285
-
In vivo aspects of protein folding and quality control
-
PID: 27365453
-
Balchin D, Hayer-Hartl M, Hartl FU. In vivo aspects of protein folding and quality control. Science. 2016;353:aac4354.
-
(2016)
Science
, vol.353
, pp. aac4354
-
-
Balchin, D.1
Hayer-Hartl, M.2
Hartl, F.U.3
-
10
-
-
4043076224
-
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis
-
PID: 15289376
-
Okada K, Minamino T, Tsukamoto Y, et al. Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation. 2004;110:705–12.
-
(2004)
Circulation
, vol.110
, pp. 705-712
-
-
Okada, K.1
Minamino, T.2
Tsukamoto, Y.3
-
11
-
-
84921688974
-
Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury
-
COI: 1:CAS:528:DC%2BC2MXhsVWntrg%3D, PID: 25302413
-
Cross MJ, Berridge BR, Clements PJ, et al. Physiological, pharmacological and toxicological considerations of drug-induced structural cardiac injury. Br J Pharmacol. 2015;172:957–74.
-
(2015)
Br J Pharmacol
, vol.172
, pp. 957-974
-
-
Cross, M.J.1
Berridge, B.R.2
Clements, P.J.3
-
12
-
-
79952095377
-
Cardiotoxicity associated with targeting kinase pathways in cancer
-
COI: 1:CAS:528:DC%2BC3MXis1eksL8%3D, PID: 21177772
-
Mellor HR, Bell AR, Valentin JP, Roberts RR. Cardiotoxicity associated with targeting kinase pathways in cancer. Toxicol Sci. 2011;120:14–32.
-
(2011)
Toxicol Sci
, vol.120
, pp. 14-32
-
-
Mellor, H.R.1
Bell, A.R.2
Valentin, J.P.3
Roberts, R.R.4
-
13
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
PID: 16862153
-
Kerkelä R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med. 2006;12:908–16.
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkelä, R.1
Grazette, L.2
Yacobi, R.3
-
14
-
-
79956014819
-
Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells
-
PID: 20574031
-
Yoon YH, Cho KS, Hwang JJ, Lee SJ, Choi JA, Koh JY. Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells. Invest Ophthalmol Vis Sci. 2010;51:6030–7.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 6030-6037
-
-
Yoon, Y.H.1
Cho, K.S.2
Hwang, J.J.3
Lee, S.J.4
Choi, J.A.5
Koh, J.Y.6
-
15
-
-
0347357617
-
Protein folding and misfolding
-
COI: 1:CAS:528:DC%2BD3sXpvVGmtbk%3D, PID: 14685248
-
Dobson CM. Protein folding and misfolding. Nature. 2003;426:884–90.
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
16
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
COI: 1:CAS:528:DC%2BC38XnvVeltQ%3D%3D, PID: 22251901
-
Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol. 2012;13:89–102.
-
(2012)
Nat Rev Mol Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
17
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
COI: 1:CAS:528:DC%2BC3MXhsV2mu7jL, PID: 22116877
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011;334:1081–6.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
18
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
COI: 1:CAS:528:DC%2BC3MXisFKntL0%3D, PID: 21364565
-
Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol. 2011;13:184–90.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
19
-
-
65349135431
-
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe−/− and Ldlr−/− mice lacking CHOP
-
COI: 1:CAS:528:DC%2BD1MXosVCks7w%3D, PID: 19416717
-
Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I. Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe−/− and Ldlr−/− mice lacking CHOP. Cell Metab. 2009;9:474–81.
-
(2009)
Cell Metab
, vol.9
, pp. 474-481
-
-
Thorp, E.1
Li, G.2
Seimon, T.A.3
Kuriakose, G.4
Ron, D.5
Tabas, I.6
-
20
-
-
72949099849
-
Functional alterations of cardiac proteasomes under physiological and pathological conditions
-
COI: 1:CAS:528:DC%2BD1MXhs1Wks7nP, PID: 19684034
-
Tsukamoto O, Minamino T, Kitakaze M. Functional alterations of cardiac proteasomes under physiological and pathological conditions. Cardiovasc Res. 2010;85:339–46.
-
(2010)
Cardiovasc Res
, vol.85
, pp. 339-346
-
-
Tsukamoto, O.1
Minamino, T.2
Kitakaze, M.3
-
21
-
-
80051978811
-
The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation
-
COI: 1:CAS:528:DC%2BC3MXhtVGlu7fO, PID: 21860393
-
Weissman AM, Shabek N, Ciechanover A. The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation. Nat Rev Mol Cell Biol. 2011;12:605–20.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 605-620
-
-
Weissman, A.M.1
Shabek, N.2
Ciechanover, A.3
-
22
-
-
85015396837
-
Protein mislocalization: mechanisms, functions and clinical applications in cancer
-
Wang X, Li S. Protein mislocalization: mechanisms, functions and clinical applications in cancer. Biochim Biophys Acta. 1846;2014:13–25.
-
(1846)
Biochim Biophys Acta
, vol.2014
, pp. 13-25
-
-
Wang, X.1
Li, S.2
-
23
-
-
84862741327
-
The ubiquitin-proteasome system and cardiovascular disease
-
COI: 1:CAS:528:DC%2BC38XhsF2jtr%2FI, PID: 22727426
-
Powell SR, Herrmann J, Lerman A, Patterson C, Wang X. The ubiquitin-proteasome system and cardiovascular disease. Prog Mol Biol Transl Sci. 2012;109:295–346.
-
(2012)
Prog Mol Biol Transl Sci
, vol.109
, pp. 295-346
-
-
Powell, S.R.1
Herrmann, J.2
Lerman, A.3
Patterson, C.4
Wang, X.5
-
24
-
-
84865497050
-
Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice
-
COI: 1:CAS:528:DC%2BC38Xht1Slsr%2FP, PID: 22740087
-
Tian Z, Zheng H, Li J, Li Y, Su H, Wang X. Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice. Circ Res. 2012;111:532–42.
-
(2012)
Circ Res
, vol.111
, pp. 532-542
-
-
Tian, Z.1
Zheng, H.2
Li, J.3
Li, Y.4
Su, H.5
Wang, X.6
-
25
-
-
80052386730
-
Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice
-
COI: 1:CAS:528:DC%2BC3MXhtFOhsbfF, PID: 21841311
-
Li J, Horak KM, Su H, Sanbe A, Robbins J, Wang X. Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice. J Clin Invest. 2011;121:3689–700.
-
(2011)
J Clin Invest
, vol.121
, pp. 3689-3700
-
-
Li, J.1
Horak, K.M.2
Su, H.3
Sanbe, A.4
Robbins, J.5
Wang, X.6
-
26
-
-
36249025723
-
Autophagy: process and function
-
COI: 1:CAS:528:DC%2BD2sXhtlGmsrjP, PID: 18006683
-
Mizushima N. Autophagy: process and function. Genes Dev. 2007;21:2861–73.
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
27
-
-
27644493346
-
The pleiotropic role of autophagy: from protein metabolism to bactericide
-
COI: 1:CAS:528:DC%2BD2MXhtFCjt7%2FP, PID: 16247501
-
Mizushima N. The pleiotropic role of autophagy: from protein metabolism to bactericide. Cell Death Differ. 2005;12(Suppl 2):1535–41.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1535-1541
-
-
Mizushima, N.1
-
28
-
-
77956404377
-
Eaten alive: a history of macroautophagy
-
COI: 1:CAS:528:DC%2BC3cXhtFSju7zE, PID: 20811353
-
Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol. 2010;12:814–22.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
29
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
COI: 1:CAS:528:DC%2BD1cXhtFehtb8%3D, PID: 18191218
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27–42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
30
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
COI: 1:CAS:528:DC%2BD2sXkvVOgsr4%3D, PID: 17450150
-
Nakai A, Yamaguchi O, Takeda T, et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med. 2007;13:619–24.
-
(2007)
Nat Med
, vol.13
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
-
31
-
-
79956126271
-
Oxidative stress stimulates autophagic flux during ischemia/reperfusion
-
COI: 1:CAS:528:DC%2BC3MXlvFOisLo%3D, PID: 20812860
-
Hariharan N, Zhai P, Sadoshima J. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal. 2011;14:2179–90.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2179-2190
-
-
Hariharan, N.1
Zhai, P.2
Sadoshima, J.3
-
32
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
-
COI: 1:CAS:528:DC%2BD2sXjtlWmsbo%3D, PID: 17332429
-
Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res. 2007;100:914–22.
-
(2007)
Circ Res
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
-
34
-
-
84961780854
-
Cardio-oncology: an update on cardiotoxicity of cancer-related treatment
-
COI: 1:CAS:528:DC%2BC28Xktlajtrc%3D, PID: 26987914
-
Lenneman CG, Sawyer DB. Cardio-oncology: an update on cardiotoxicity of cancer-related treatment. Circ Res. 2016;118:1008–20.
-
(2016)
Circ Res
, vol.118
, pp. 1008-1020
-
-
Lenneman, C.G.1
Sawyer, D.B.2
-
35
-
-
74049097142
-
Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention
-
COI: 1:CAS:528:DC%2BC3cXkt1Cksg%3D%3D, PID: 20007921
-
Albini A, Pennesi G, Donatelli F, Cammarota R, De Flora S, Noonan DM. Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. J Natl Cancer Inst. 2010;102:14–25.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 14-25
-
-
Albini, A.1
Pennesi, G.2
Donatelli, F.3
Cammarota, R.4
De Flora, S.5
Noonan, D.M.6
-
36
-
-
84865042947
-
5-fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress
-
COI: 1:CAS:528:DC%2BC38XhslyitrbI, PID: 22812382
-
Lamberti M, Porto S, Marra M, et al. 5-fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress. J Exp Clin Cancer Res. 2012;31:60.
-
(2012)
J Exp Clin Cancer Res
, vol.31
, pp. 60
-
-
Lamberti, M.1
Porto, S.2
Marra, M.3
-
37
-
-
84890559945
-
Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event
-
COI: 1:CAS:528:DC%2BC3sXhvVamtr7O, PID: 24046265
-
Rossato LG, Costa VM, Vilas-Boas V, et al. Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event. Cardiovasc Toxicol. 2013;13:413–25.
-
(2013)
Cardiovasc Toxicol
, vol.13
, pp. 413-425
-
-
Rossato, L.G.1
Costa, V.M.2
Vilas-Boas, V.3
-
38
-
-
2342591455
-
The discovery of receptor tyrosine kinases: targets for cancer therapy
-
COI: 1:CAS:528:DC%2BD2cXjsFSlu7g%3D, PID: 15122207
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer. 2004;4:361–70.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
39
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
PID: 19104514
-
Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer. 2009;9:28–39.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
40
-
-
0141528828
-
Chronic myeloid leukemia--advances in biology and new approaches to treatment
-
COI: 1:CAS:528:DC%2BD3sXotVGgsLc%3D, PID: 14534339
-
Goldman JM, Melo JV. Chronic myeloid leukemia--advances in biology and new approaches to treatment. N Engl J Med. 2003;349:1451–64.
-
(2003)
N Engl J Med
, vol.349
, pp. 1451-1464
-
-
Goldman, J.M.1
Melo, J.V.2
-
41
-
-
84944381935
-
ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity
-
COI: 1:CAS:528:DC%2BC28XhtFOqtr3P, PID: 26254336
-
Belmonte F, Das S, Sysa-Shah P, et al. ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity. Am J Physiol Heart Circ Physiol. 2015;309:H1271–80.
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.309
, pp. H1271-H1280
-
-
Belmonte, F.1
Das, S.2
Sysa-Shah, P.3
-
42
-
-
33645566250
-
Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats
-
COI: 1:CAS:528:DC%2BD28XpsFKgsbY%3D, PID: 16597375
-
Saad SY, Alkharfy KM, Arafah MM. Cardiotoxic effects of arsenic trioxide/imatinib mesilate combination in rats. J Pharm Pharmacol. 2006;58:567–73.
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 567-573
-
-
Saad, S.Y.1
Alkharfy, K.M.2
Arafah, M.M.3
-
43
-
-
77951494873
-
Targeted cancer therapies in the twenty-first century: lessons from imatinib
-
COI: 1:CAS:528:DC%2BC3cXkvFCntb8%3D, PID: 20237469
-
Stegmeier F, Warmuth M, Sellers WR, Dorsch M. Targeted cancer therapies in the twenty-first century: lessons from imatinib. Clin Pharmacol Ther. 2010;87:543–52.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 543-552
-
-
Stegmeier, F.1
Warmuth, M.2
Sellers, W.R.3
Dorsch, M.4
-
44
-
-
84977469766
-
Cardiotoxicity associated with targeted cancer therapies
-
COI: 1:STN:280:DC%2BC1c%2Fht1Smtw%3D%3D, PID: 27123262
-
Chen ZI, Ai DI. Cardiotoxicity associated with targeted cancer therapies. Mol Clin Oncol. 2016;4:675–81.
-
(2016)
Mol Clin Oncol
, vol.4
, pp. 675-681
-
-
Chen, Z.I.1
Ai, D.I.2
-
45
-
-
84865760057
-
Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase
-
COI: 1:CAS:528:DC%2BC38Xht1ynsL7F, PID: 22641616
-
Hu W, Lu S, McAlpine I, et al. Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase. Toxicol Sci. 2012;129:188–99.
-
(2012)
Toxicol Sci
, vol.129
, pp. 188-199
-
-
Hu, W.1
Lu, S.2
McAlpine, I.3
-
46
-
-
84944522481
-
Clinical features of pulmonary arterial hypertension in patients receiving dasatinib
-
COI: 1:CAS:528:DC%2BC2MXhslegurzK, PID: 26284693
-
Shah NP, Wallis N, Farber HW, et al. Clinical features of pulmonary arterial hypertension in patients receiving dasatinib. Am J Hematol. 2015;90:1060–4.
-
(2015)
Am J Hematol
, vol.90
, pp. 1060-1064
-
-
Shah, N.P.1
Wallis, N.2
Farber, H.W.3
-
47
-
-
2342613652
-
The proteasome: a suitable antineoplastic target
-
COI: 1:CAS:528:DC%2BD2cXjsFSlu7k%3D, PID: 15122206
-
Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer. 2004;4:349–60.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
48
-
-
0034635952
-
Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression
-
COI: 1:CAS:528:DC%2BD3cXislSgsLc%3D, PID: 10725400
-
Li B, Dou QP. Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression. Proc Natl Acad Sci U S A. 2000;97:3850–5.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 3850-3855
-
-
Li, B.1
Dou, Q.P.2
-
49
-
-
84907362479
-
Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system
-
COI: 1:CAS:528:DC%2BC2cXhsVGisrbP, PID: 25092212
-
Dou QP, Zonder JA. Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system. Curr Cancer Drug Targets. 2014;14:517–36.
-
(2014)
Curr Cancer Drug Targets
, vol.14
, pp. 517-536
-
-
Dou, Q.P.1
Zonder, J.A.2
-
50
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
COI: 1:CAS:528:DC%2BD3MXivFGqsL0%3D, PID: 11306489
-
Hideshima T, Richardson P, Chauhan D, et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 2001;61:3071–6.
-
(2001)
Cancer Res
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
-
51
-
-
84966699274
-
Endoplasmic-reticulum stress pathway-associated mechanisms of action of proteasome inhibitors in multiple myeloma
-
COI: 1:CAS:528:DC%2BC28XnvFWru74%3D, PID: 27169614
-
Ri M. Endoplasmic-reticulum stress pathway-associated mechanisms of action of proteasome inhibitors in multiple myeloma. Int J Hematol. 2016;104:273–80.
-
(2016)
Int J Hematol
, vol.104
, pp. 273-280
-
-
Ri, M.1
-
52
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
COI: 1:CAS:528:DC%2BD3cXjsVSnsbg%3D, PID: 10807576
-
Oda E, Ohki R, Murasawa H, et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science. 2000;288:1053–8.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
-
53
-
-
34447123834
-
Unexpected cardiotoxicity in haematological bortezomib treated patients
-
PID: 17561972
-
Enrico O, Gabriele B, Nadia C, et al. Unexpected cardiotoxicity in haematological bortezomib treated patients. Br J Haematol. 2007;138:396–7.
-
(2007)
Br J Haematol
, vol.138
, pp. 396-397
-
-
Enrico, O.1
Gabriele, B.2
Nadia, C.3
-
54
-
-
77957356238
-
Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts
-
COI: 1:CAS:528:DC%2BC3cXhsVSltLvI, PID: 20601385
-
Tang M, Li J, Huang W, et al. Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts. Cardiovasc Res. 2010;88:424–33.
-
(2010)
Cardiovasc Res
, vol.88
, pp. 424-433
-
-
Tang, M.1
Li, J.2
Huang, W.3
-
55
-
-
84986296809
-
Carfilzomib and the cardiorenal system in myeloma: an endothelial effect?
-
COI: 1:STN:280:DC%2BC28nhslygtA%3D%3D, PID: 26771810
-
Rosenthal A, Luthi J, Belohlavek M, et al. Carfilzomib and the cardiorenal system in myeloma: an endothelial effect? Blood Cancer J. 2016;6:e384.
-
(2016)
Blood Cancer J
, vol.6
-
-
Rosenthal, A.1
Luthi, J.2
Belohlavek, M.3
-
56
-
-
77955906955
-
Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection?
-
COI: 1:CAS:528:DC%2BC3cXhtVGmt73E, PID: 20728697
-
Sawyer DB, Peng X, Chen B, Pentassuglia L, Lim CC. Mechanisms of anthracycline cardiac injury: can we identify strategies for cardioprotection? Prog Cardiovasc Dis. 2010;53:105–13.
-
(2010)
Prog Cardiovasc Dis
, vol.53
, pp. 105-113
-
-
Sawyer, D.B.1
Peng, X.2
Chen, B.3
Pentassuglia, L.4
Lim, C.C.5
-
57
-
-
0033965484
-
Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription
-
COI: 1:CAS:528:DC%2BD3cXlt1ehtg%3D%3D, PID: 10625299
-
Arai M, Yoguchi A, Takizawa T, et al. Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription. Circ Res. 2000;86:8–14.
-
(2000)
Circ Res
, vol.86
, pp. 8-14
-
-
Arai, M.1
Yoguchi, A.2
Takizawa, T.3
-
58
-
-
64149124058
-
ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity
-
COI: 1:CAS:528:DC%2BD1MXktFCitb8%3D
-
An J, Li P, Li J, Dietz R, Donath S. ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity. J Mol Med (Berl). 2009;87:401–10.
-
(2009)
J Mol Med (Berl)
, vol.87
, pp. 401-410
-
-
An, J.1
Li, P.2
Li, J.3
Dietz, R.4
Donath, S.5
-
59
-
-
84961223599
-
Doxorubicin blocks cardiomyocyte autophagic flux by inhibiting lysosome acidification
-
COI: 1:CAS:528:DC%2BC28XmvFShtrY%3D, PID: 26984939
-
Li DL, Wang ZV, Ding G, et al. Doxorubicin blocks cardiomyocyte autophagic flux by inhibiting lysosome acidification. Circulation. 2016;133:1668–87.
-
(2016)
Circulation
, vol.133
, pp. 1668-1687
-
-
Li, D.L.1
Wang, Z.V.2
Ding, G.3
-
60
-
-
33646581674
-
Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress
-
COI: 1:CAS:528:DC%2BD28Xmt1aru74%3D, PID: 16539653
-
Kubota K, Niinuma Y, Kaneko M, et al. Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress. J Neurochem. 2006;97:1259–68.
-
(2006)
J Neurochem
, vol.97
, pp. 1259-1268
-
-
Kubota, K.1
Niinuma, Y.2
Kaneko, M.3
-
61
-
-
84884235347
-
Urea cycle disorder drug approved
-
COI: 1:CAS:528:DC%2BC3sXltlOhsrg%3D, PID: 23563410
-
Guha M. Urea cycle disorder drug approved. Nat Biotechnol. 2013;31:274.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 274
-
-
Guha, M.1
-
62
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
COI: 1:CAS:528:DC%2BD28XhtVyktbbN, PID: 17051204
-
Rubinsztein DC. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature. 2006;443:780–6.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
63
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
-
COI: 1:CAS:528:DC%2BD2sXhsFKgsLs%3D, PID: 17135238
-
Ding WX, Ni HM, Gao W, et al. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem. 2007;282:4702–10.
-
(2007)
J Biol Chem
, vol.282
, pp. 4702-4710
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
-
64
-
-
84908134087
-
Global extent of chloroquine-resistant plasmodium vivax: a systematic review and meta-analysis
-
PID: 25213732
-
Price RN, von Seidlein L, Valecha N, Nosten F, Baird JK, White NJ. Global extent of chloroquine-resistant plasmodium vivax: a systematic review and meta-analysis. Lancet Infect Dis. 2014;14:982–91.
-
(2014)
Lancet Infect Dis
, vol.14
, pp. 982-991
-
-
Price, R.N.1
von Seidlein, L.2
Valecha, N.3
Nosten, F.4
Baird, J.K.5
White, N.J.6
-
65
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
COI: 1:CAS:528:DC%2BC3MXitVSqtLc%3D, PID: 21325294
-
Amaravadi RK, Lippincott-Schwartz J, Yin XM, et al. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res. 2011;17:654–66.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
-
66
-
-
84871940714
-
Chloroquine in cancer therapy: a double-edged sword of autophagy
-
COI: 1:CAS:528:DC%2BC3sXjs1Wqtg%3D%3D, PID: 23288916
-
Kimura T, Takabatake Y, Takahashi A, Isaka Y. Chloroquine in cancer therapy: a double-edged sword of autophagy. Cancer Res. 2013;73:3–7.
-
(2013)
Cancer Res
, vol.73
, pp. 3-7
-
-
Kimura, T.1
Takabatake, Y.2
Takahashi, A.3
Isaka, Y.4
-
67
-
-
84904062322
-
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
-
COI: 1:CAS:528:DC%2BC2MXkt1agurs%3D, PID: 24991840
-
Rosenfeld MR, Ye X, Supko JG, et al. A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme. Autophagy. 2014;10:1359–68.
-
(2014)
Autophagy
, vol.10
, pp. 1359-1368
-
-
Rosenfeld, M.R.1
Ye, X.2
Supko, J.G.3
-
68
-
-
84904062323
-
Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma
-
COI: 1:CAS:528:DC%2BC2MXkt1agur4%3D, PID: 24991839
-
Rangwala R, Leone R, Chang YC, et al. Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma. Autophagy. 2014;10:1369–79.
-
(2014)
Autophagy
, vol.10
, pp. 1369-1379
-
-
Rangwala, R.1
Leone, R.2
Chang, Y.C.3
-
69
-
-
84868698039
-
Hydroxychloroquine-induced cardiomyopathy that presented as pulmonary hypertension: a newly noted complication
-
PID: 23154245
-
Bae SM, Jung HO, Ihm SM, et al. Hydroxychloroquine-induced cardiomyopathy that presented as pulmonary hypertension: a newly noted complication. Cardiology. 2012;123:197–200.
-
(2012)
Cardiology
, vol.123
, pp. 197-200
-
-
Bae, S.M.1
Jung, H.O.2
Ihm, S.M.3
-
70
-
-
85006129703
-
-
High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy, Physiol Rep
-
Chaanine AH, Gordon RE, Nonnenmacher M, Kohlbrenner E, Benard L, Hajjar RJ. High-dose chloroquine is metabolically cardiotoxic by inducing lysosomes and mitochondria dysfunction in a rat model of pressure overload hypertrophy. Physiol Rep. 2015.
-
(2015)
Hajjar RJ
-
-
Chaanine, A.H.1
Gordon, R.E.2
Nonnenmacher, M.3
Kohlbrenner, E.4
Benard, L.5
-
71
-
-
84955282878
-
Cancer therapy-related cardiac dysfunction and heart failure: part 1: definitions, pathophysiology, risk factors, and imaging
-
PID: 26747861
-
Bloom MW, Hamo CE, Cardinale D, et al. Cancer therapy-related cardiac dysfunction and heart failure: part 1: definitions, pathophysiology, risk factors, and imaging. Circ Heart Fail. 2016;9:e002661.
-
(2016)
Circ Heart Fail.
, vol.9
-
-
Bloom, M.W.1
Hamo, C.E.2
Cardinale, D.3
-
72
-
-
84959538467
-
Cancer therapy-related cardiac dysfunction and heart failure: part 2: prevention, treatment, guidelines, and future directions
-
COI: 1:CAS:528:DC%2BC28XjtVKmu7Y%3D, PID: 26839395
-
Hamo CE, Bloom MW, Cardinale D, et al. Cancer therapy-related cardiac dysfunction and heart failure: part 2: prevention, treatment, guidelines, and future directions. Circ Heart Fail. 2016;9:e002843.
-
(2016)
Circ Heart Fail
, vol.9
-
-
Hamo, C.E.1
Bloom, M.W.2
Cardinale, D.3
|