Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L

Autophagy

Volumn 13, Issue 2, 2017, Pages 404-422

  Wang, Qilong ^a   Wu, Shengnan ^a   Zhu, Huaiping ^a   Ding, Ye ^a   Dai, Xiaoyan ^a   Ouyang, Changhan ^a   Han, Young Min ^a   Xie, Zhonglin ^a   Zou, Ming Hui ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

AMPK; autophagy; DNM1L; endothelial dysfunction; mitochondrial fission; PRKAA AMPK catalytic subunit

Indexed keywords

ACETYLCHOLINE; AUTOPHAGY RELATED PROTEIN 7; BETA ACTIN; CD31 ANTIGEN; CHLOROQUINE; DYNAMIN 1 LIKE; MAMMALIAN TARGET OF RAPAMYCIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; PROTEIN KINASE ADENOSINE PHOSPHATE ACTIVATED ALPHA CATALYTIC SUBUNIT 1; PROTEIN KINASE ADENOSINE PHOSPHATE ACTIVATED ALPHA CATALYTIC SUBUNIT 2; RAPAMYCIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNM1L PROTEIN, HUMAN; DNM1L PROTEIN, MOUSE; DYNAMIN; GUANOSINE TRIPHOSPHATASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHOSERINE; PRKAA1 PROTEIN, HUMAN; PRKAA2 PROTEIN, HUMAN; SEQUESTOSOME 1; SQSTM1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA ENDOTHELIUM; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; ENDOTHELIAL DYSFUNCTION; GENE SILENCING; KNOCKOUT MOUSE; MITOCHONDRIAL DYNAMICS; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; VASODILATATION; ANIMAL; AORTA; C57BL MOUSE; CELL SEPARATION; DRUG EFFECTS; GENE DELETION; HUMAN; METABOLISM; PHOSPHORYLATION; ULTRASTRUCTURE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AORTA; AUTOPHAGY; CELL SEPARATION; DYNAMINS; ENDOTHELIUM, VASCULAR; GENE DELETION; GTP PHOSPHOHYDROLASES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEOLYSIS; SEQUESTOSOME-1 PROTEIN; SIROLIMUS; VASODILATION;

EID: 85010664504     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1263776     Document Type: Article

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