Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence

Journal of Virology

Volumn 85, Issue 19, 2011, Pages 10154-10166

  Stein, David A ^a   Perry, Stuart T ^b   Buck, Michael D ^b   Oehmen, Christopher S ^c   Fischer, Matthew A ^a   Poore, Elizabeth ^a   Smith, Jessica L ^a   Lancaster, Alissa M ^a   Hirsch, Alec J ^a   Slifka, Mark K ^a   Nelson, Jay A ^a   Shresta, Sujan ^b   Früh, Klaus ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DC 3; SILENCER IN VIVO READY SIRNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AG129 MOUSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DEPENDENT ENHANCEMENT; ARTICLE; CELL CULTURE; DENGUE; DENGUE VIRUS; DENGUE VIRUS 2; DISEASE SEVERITY; DRUG TARGETING; GENETIC STRAIN; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE; SEROTYPE; SURVIVAL TIME; VIRUS GENOME; VIRUS INHIBITION; VIRUS STRAIN; VIRUS TITRATION; WEIGHT REDUCTION;

ANIMALS; ANTIBODY-DEPENDENT ENHANCEMENT; ANTIVIRAL AGENTS; BIOLOGICAL PRODUCTS; BODY WEIGHT; CELL CULTURE TECHNIQUES; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; DENGUE; DENGUE VIRUS; DISEASE MODELS, ANIMAL; HUMANS; MICE; RNA, SMALL INTERFERING; RODENT DISEASES; SURVIVAL ANALYSIS;

DENGUE VIRUS; DENGUE VIRUS GROUP; MUS;

EID: 80053997303     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05298-11     Document Type: Article

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