PRKAA1/AMPKα1 is required for autophagydependent mitochondrial clearance during erythrocyte maturation

Autophagy

Volumn 10, Issue 9, 2014, Pages 1522-1534

  Zhu, Hiping ^a   Foretz, Marc ^b,c   Xie, Zhonglin ^a   Zhang, Miao ^a   Zhu, Zhiren ^d   Xing, Junjie ^a   Leclerc, Jocelyne ^b,c   Gaudry, Murielle ^b,c   Viollet, Benoit ^b,c   Zou, Ming Hui ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b INSTITUT COCHIN   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

AMPK; Autophagy; Erythrocyte; Mitophagy; Oxidative stress

Indexed keywords

ANTIOXIDANT; BECLIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA1; MEMBRANE PROTEIN; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; ULK1 PROTEIN; UNCLASSIFIED DRUG; PRKAA1 PROTEIN, HUMAN; PRKAB1 PROTEIN, MOUSE;

ANEMIA; ARTICLE; AUTOPHAGY; BONE MARROW TRANSPLANTATION; CELL DESTRUCTION; CELL MATURATION; CONTROLLED STUDY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ERYTHROCYTE; ERYTHROCYTE LIFESPAN; ERYTHROLEUKEMIA CELL; HEMATOLOGIC DISEASE; HUMAN; HUMAN CELL; K562 CELL LINE; MITOCHONDRION; MOUSE; MYELODYSPLASTIC SYNDROME; NONHUMAN; OXIDATIVE STRESS; PROTEIN METABOLISM; SPLEEN SIZE; SPLENOMEGALY; WILD TYPE; ANIMAL; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; AUTOPHAGY; CELL LINE; ERYTHROCYTES; HUMANS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84907171686     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.29197     Document Type: Article

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