Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A

Structure

Volumn 25, Issue 2, 2017, Pages 341-352

  Markovic Mueller, Sandra ^a   Stuttfeld, Edward ^b   Asthana, Mayanka ^a   Weinert, Tobias ^a   Bliven, Spencer ^a,c   Goldie, Kenneth N ^b   Kisko, Kaisa ^a   Capitani, Guido ^a   Ballmer Hofer, Kurt ^a  

^a PAUL SCHERRER INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

angiogenesis; extracellular domain; receptor tyrosine kinase; single particle negative stain electron microscopy; small angle X ray scattering; vascular endothelial growth factor; VEGF receptor; X ray crystallography

Indexed keywords

IMMUNOGLOBULIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; LIGAND; PROTEIN BINDING; RECOMBINANT PROTEIN; VEGFA PROTEIN, HUMAN;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVATION; ENZYME INHIBITION; GLYCOSYLATION; HYDROGEN BOND; IMMUNOGLOBULIN DOMAIN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; ALPHA HELIX; AMINO ACID SEQUENCE; BETA SHEET; BINDING SITE; CHEMISTRY; ELECTRON MICROSCOPY; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION; HUMANS; LIGANDS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; THERMODYNAMICS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 85009799929     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2016.12.012     Document Type: Article

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