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Volumn 288, Issue 12, 2013, Pages 8176-8186

The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology

Author keywords

[No Author keywords available]

Indexed keywords

PLANTS (BOTANY); POLYSACCHARIDES; TUMORS;

EID: 84875459759     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.439299     Document Type: Article
Times cited : (28)

References (56)
  • 1
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • Tammela, T., and Alitalo, K. (2010) Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140, 460-476
    • (2010) Cell , vol.140 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 2
    • 13844265843 scopus 로고    scopus 로고
    • Focus on lymphangiogenesis in tumor metastasis
    • DOI 10.1016/j.ccr.2005.01.017
    • Achen, M. G., McColl, B. K., and Stacker, S. A. (2005) Focus on lymphangiogenesis in tumor metastasis. Cancer Cell 7, 121-127 (Pubitemid 40248338)
    • (2005) Cancer Cell , vol.7 , Issue.2 , pp. 121-127
    • Achen, M.G.1    McColl, B.K.2    Stacker, S.A.3
  • 3
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • Potente, M., Gerhardt, H., and Carmeliet, P. (2011) Basic and therapeutic aspects of angiogenesis. Cell 146, 873-887
    • (2011) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 7
    • 0141621049 scopus 로고    scopus 로고
    • Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor-binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens
    • DOI 10.1074/jbc.M301194200
    • Wise, L. M., Ueda, N., Dryden, N. H., Fleming, S. B., Caesar, C., Roufail, S., Achen, M. G., Stacker, S. A., and Mercer, A. A. (2003) Viral vascular endothelial growth factors vary extensively in amino acid sequence, receptor- binding specificities, and the ability to induce vascular permeability yet are uniformly active mitogens. J. Biol. Chem. 278, 38004-38014 (Pubitemid 37175331)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 38004-38014
    • Wise, L.M.1    Ueda, N.2    Dryden, N.H.3    Fleming, S.B.4    Caesar, C.5    Roufail, S.6    Achen, M.G.7    Stacker, S.A.8    Mercer, A.A.9
  • 11
    • 0036844702 scopus 로고    scopus 로고
    • Molecular control of lymphangiogenesis
    • DOI 10.1002/bies.10173
    • Baldwin, M. E., Stacker, S. A., and Achen, M. G. (2002) Molecular control of lymphangiogenesis. Bioessays 24, 1030-1040 (Pubitemid 35326161)
    • (2002) BioEssays , vol.24 , Issue.11 , pp. 1030-1040
    • Baldwin, M.E.1    Stacker, S.A.2    Achen, M.G.3
  • 12
    • 84866909298 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-D: Signalling mechanisms, biology and clinical relevance
    • Achen, M. G., Stacker, S.A. (2012) Vascular endothelial growth factor-D: signalling mechanisms, biology and clinical relevance. Growth Factors 30, 283-296
    • (2012) Growth Factors , vol.30 , pp. 283-296
    • Achen, M.G.1    Stacker, S.A.2
  • 15
    • 33748190835 scopus 로고    scopus 로고
    • Lymphatic vessels in cancer metastasis: Bridging the gaps
    • DOI 10.1093/carcin/bgl031
    • Shayan, R., Achen, M. G., and Stacker, S. A. (2006) Lymphatic vessels in cancer metastasis: bridging the gaps. Carcinogenesis 27, 1729-1738 (Pubitemid 44307827)
    • (2006) Carcinogenesis , vol.27 , Issue.9 , pp. 1729-1738
    • Shayan, R.1    Achen, M.G.2    Stacker, S.A.3
  • 18
    • 0037086278 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-D expression is an independent prognostic marker for survival in colorectal carcinoma
    • White, J. D., Hewett, P. W., Kosuge, D., McCulloch, T., Enholm, B. C., Carmichael, J., and Murray, J. C. (2002) Vascular endothelial growth factor- D expression is an independent prognostic marker for survival in colorectal carcinoma. Cancer Res. 62, 1669-1675 (Pubitemid 34408487)
    • (2002) Cancer Research , vol.62 , Issue.6 , pp. 1669-1675
    • White, J.D.1    Hewett, P.W.2    Kosuge, D.3    McCulloch, T.4    Enholm, B.C.5    Carmichael, J.6    Murray, J.C.7
  • 19
    • 33644825389 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-D and its receptor VEGFR-3: Two novel independent prognostic markers in gastric adenocarcinoma
    • DOI 10.1200/JCO.2004.00.3467
    • Jüttner, S., Wissmann, C., Jöns, T., Vieth, M., Hertel, J., Gretschel, S., Schlag, P. M., Kemmner, W., and Höcker, M. (2006) Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognostic markers in gastric adenocarcinoma. J. Clin. Oncol. 24, 228-240 (Pubitemid 46622052)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.2 , pp. 228-240
    • Juttner, S.1    Wissmann, C.2    Jons, T.3    Vieth, M.4    Hertel, J.5    Gretschel, S.6    Schlag, P.M.7    Kemmner, W.8    Hocker, M.9
  • 20
    • 36249027630 scopus 로고    scopus 로고
    • VEGF-D in association with VEGFR-3 promotes nodal metastasis in human invasive lobular breast cancer
    • DOI 10.1309/7FXVRMXF58PVRJUH
    • van Iterson, V., Leidenius, M., von Smitten, K., Bono, P., and Heikkilä, P. (2007) VEGF-D in association with VEGFR-3 promotes nodal metastasis in human invasive lobular breast cancer. Am. J. Clin. Pathol. 128, 759-766 (Pubitemid 350133986)
    • (2007) American Journal of Clinical Pathology , vol.128 , Issue.5 , pp. 759-766
    • Van Iterson, V.1    Leidenius, M.2    Von Smitten, K.3    Bono, P.4    Heikkila, P.5
  • 22
    • 10344237560 scopus 로고    scopus 로고
    • Lymphangiogenic growth factors as markers of tumor metastasis
    • DOI 10.1111/j.1600-0463.2004.apm11207-0812.x
    • Stacker, S. A., Williams, R. A., and Achen, M. G. (2004) Lymphangiogenic growth factors as markers of tumor metastasis. APMIS 112, 539-549 (Pubitemid 39626059)
    • (2004) APMIS , vol.112 , Issue.7-8 , pp. 539-549
    • Stacker, S.A.1    Williams, R.A.2    Achen, M.G.3
  • 23
    • 33646835413 scopus 로고    scopus 로고
    • Targeting lymphangiogenesis to prevent tumour metastasis
    • DOI 10.1038/sj.bjc.6603120, PII 6603120
    • Achen, M. G., Mann, G. B., and Stacker, S. A. (2006) Targeting lymphangiogenesis to prevent tumour metastasis. Br. J. Cancer 94, 1355-1360 (Pubitemid 43772266)
    • (2006) British Journal of Cancer , vol.94 , Issue.10 , pp. 1355-1360
    • Achen, M.G.1    Mann, G.B.2    Stacker, S.A.3
  • 26
    • 80052713566 scopus 로고    scopus 로고
    • Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells
    • Grau, S., Thorsteinsdottir, J., von Baumgarten, L., Winkler, F., Tonn, J. C., and Schichor, C. (2011) Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells. J. Neurooncol. 104, 103-112
    • (2011) J. Neurooncol. , vol.104 , pp. 103-112
    • Grau, S.1    Thorsteinsdottir, J.2    Von Baumgarten, L.3    Winkler, F.4    Tonn, J.C.5    Schichor, C.6
  • 31
    • 0035941203 scopus 로고    scopus 로고
    • Multiple forms of mouse vascular endothelial growth factor-D are generated byRNAsplicing and proteolysis
    • Baldwin, M. E., Roufail, S., Halford, M. M., Alitalo, K., Stacker, S. A., and Achen, M. G. (2001) Multiple forms of mouse vascular endothelial growth factor-D are generated byRNAsplicing and proteolysis. J. Biol. Chem. 276, 44307-44314
    • (2001) J. Biol. Chem. , vol.276 , pp. 44307-44314
    • Baldwin, M.E.1    Roufail, S.2    Halford, M.M.3    Alitalo, K.4    Stacker, S.A.5    Achen, M.G.6
  • 34
    • 80051690785 scopus 로고    scopus 로고
    • Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer
    • Harris, N. C., Paavonen, K., Davydova, N., Roufail, S., Sato, T., Zhang, Y. F., Karnezis, T., Stacker, S. A., and Achen, M. G. (2011) Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer. FASEB J. 25, 2615-2625
    • (2011) FASEB J. , vol.25 , pp. 2615-2625
    • Harris, N.C.1    Paavonen, K.2    Davydova, N.3    Roufail, S.4    Sato, T.5    Zhang, Y.F.6    Karnezis, T.7    Stacker, S.A.8    Achen, M.G.9
  • 35
    • 0035150839 scopus 로고    scopus 로고
    • Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis
    • DOI 10.1002/1096-9896(2000)9999:9999<::AID-PATH757>3.0.CO;2-G
    • Achen, M. G., Williams, R. A., Minekus, M. P., Thornton, G. E., Stenvers, K., Rogers, P. A., Lederman, F., Roufail, S., and Stacker, S. A. (2001) Localization of vascular endothelial growth factor-D in malignant melanoma suggests a role in tumour angiogenesis. J. Pathol. 193, 147-154 (Pubitemid 32118124)
    • (2001) Journal of Pathology , vol.193 , Issue.2 , pp. 147-154
    • Achen, M.G.1    Williams, R.A.2    Minekus, M.P.3    Thornton, G.E.4    Stenvers, K.5    Rogers, P.A.W.6    Lederman, F.7    Roufail, S.8    Stacker, S.A.9
  • 37
    • 0033119556 scopus 로고    scopus 로고
    • Instrumental biosensors: New perspectives for the analysis of biomolecular interactions
    • DOI 10.1002/(SICI)1521-1878(199904)21:4<339::AID-BIES11>3.0.CO;2-C
    • Nice, E. C., and Catimel, B. (1999) Instrumental biosensors: new perspectives for the analysis of biomolecular interactions. Bioessays 21, 339-352 (Pubitemid 29211960)
    • (1999) BioEssays , vol.21 , Issue.4 , pp. 339-352
    • Nice, E.C.1    Catimel, B.2
  • 41
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform- specific receptor for vascular endothelial growth factor
    • DOI 10.1016/S0092-8674(00)81402-6
    • Soker, S., Takashima, S., Miao, H. Q., Neufeld, G., and Klagsbrun, M. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745 (Pubitemid 28155313)
    • (1998) Cell , vol.92 , Issue.6 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 45
    • 77649096200 scopus 로고    scopus 로고
    • Binding to the extracellular matrix and proteolytic processing: Two key mechanisms regulating vascular endothelial growth factor action
    • Ferrara, N. (2010) Binding to the extracellular matrix and proteolytic processing: two key mechanisms regulating vascular endothelial growth factor action. Mol. Biol. Cell 21, 687-690
    • (2010) Mol. Biol. Cell , vol.21 , pp. 687-690
    • Ferrara, N.1
  • 46
    • 0029937679 scopus 로고    scopus 로고
    • The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency
    • DOI 10.1074/jbc.271.13.7788
    • Keyt, B. A., Berleau, L. T., Nguyen, H. V., Chen, H., Heinsohn, H., Vandlen, R., and Ferrara, N. (1996) The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J. Biol. Chem. 271, 7788-7795 (Pubitemid 26111064)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.13 , pp. 7788-7795
    • Keyt, B.A.1    Berleau, L.T.2    Nguyen, H.V.3    Chen, H.4    Heinsohn, H.5    Vandlen, R.6    Ferrara, N.7
  • 47
    • 0027064888 scopus 로고
    • Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
    • Houck, K. A., Leung, D. W., Rowland, A. M., Winer, J., and Ferrara, N. (1992) Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J. Biol. Chem. 267, 26031-26037 (Pubitemid 23014012)
    • (1992) Journal of Biological Chemistry , vol.267 , Issue.36 , pp. 26031-26037
    • Houck, K.A.1    Leung, D.W.2    Rowland, A.M.3    Winer, J.4    Ferrara, N.5
  • 48
    • 17044458971 scopus 로고    scopus 로고
    • Ligand-induced Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3) Heterodimerization with VEGFR-2 in Primary Lymphatic Endothelial Cells Regulates Tyrosine Phosphorylation Sites
    • DOI 10.1074/jbc.M304499200
    • Dixelius, J., Makinen, T., Wirzenius, M., Karkkainen, M. J., Wernstedt, C., Alitalo, K., and Claesson-Welsh, L. (2003) Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites. J. Biol. Chem. 278, 40973-40979 (Pubitemid 37280919)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.42 , pp. 40973-40979
    • Dixelius, J.1    Makinen, T.2    Wirzenius, M.3    Karkkainen, M.J.4    Wernstedt, C.5    Alitalo, K.6    Claesson-Welsh, L.7
  • 49
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen, T. A., Arola, J., Saaristo, A., Jussila, L., Ora, A., Miettinen, M., Stacker, S. A., Achen, M. G., and Alitalo, K. (2000) VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J. 14, 2087-2096
    • (2000) FASEB J. , vol.14 , pp. 2087-2096
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3    Jussila, L.4    Ora, A.5    Miettinen, M.6    Stacker, S.A.7    Achen, M.G.8    Alitalo, K.9
  • 51
    • 79955420141 scopus 로고    scopus 로고
    • Lymphatic endothelial heparan sulfate deficiency results in altered growth responses to vascular endothelial growth factor-C (VEGF-C)
    • Yin, X., Johns, S. C., Lawrence, R., Xu, D., Reddi, K., Bishop, J. R., Varner, J. A., and Fuster, M. M. (2011) Lymphatic endothelial heparan sulfate deficiency results in altered growth responses to vascular endothelial growth factor-C (VEGF-C). J. Biol. Chem. 286, 14952-14962
    • (2011) J Biol Chem , vol.286 , pp. 14952-14962
    • Yin, X.1    Johns, S.C.2    Lawrence, R.3    Xu, D.4    Reddi, K.5    Bishop, J.R.6    Varner, J.A.7    Fuster, M.M.8
  • 52
    • 0031214153 scopus 로고    scopus 로고
    • Disulfide structure of the heparin binding domain in vascular endothelial growth factor: Characterization of posttranslational modifications in VEGF
    • DOI 10.1006/abbi.1997.0145
    • Keck, R. G., Berleau, L., Harris, R., and Keyt, B. A. (1997) Disulfide structure of the heparin binding domain in vascular endothelial growth factor: characterization of posttranslational modifications in VEGF. Arch. Biochem. Biophys. 344, 103-113 (Pubitemid 27328102)
    • (1997) Archives of Biochemistry and Biophysics , vol.344 , Issue.1 , pp. 103-113
    • Keck, R.G.1    Berleau, L.2    Harris, R.3    Keyt, B.A.4
  • 53
    • 33847343054 scopus 로고    scopus 로고
    • 121 stimulated signal transduction by the VEGFR-2 receptor
    • DOI 10.1096/fj.06-6277com
    • Shraga-Heled, N., Kessler, O., Prahst, C., Kroll, J., Augustin, H., and Neufeld, G. (2007) Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor. FASEB J. 21, 915-926 (Pubitemid 46348264)
    • (2007) FASEB Journal , vol.21 , Issue.3 , pp. 915-926
    • Shraga-Heled, N.1    Kessler, O.2    Prahst, C.3    Kroll, J.4    Augustin, H.5    Neufeld, G.6
  • 56
    • 0028091775 scopus 로고
    • Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors
    • Pajusola, K., Aprelikova, O., Pelicci, G., Weich, H., Claesson-Welsh, L., and Alitalo, K. (1994) Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors. Oncogene 9, 3545-3555 (Pubitemid 24359392)
    • (1994) Oncogene , vol.9 , Issue.12 , pp. 3545-3555
    • Pajusola, K.1    Aprelikova, O.2    Pelicci, G.3    Weich, H.4    Claesson-Welsh, L.5    Alitalo, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.