-
1
-
-
0025890065
-
Identification of tetrahydro- beta-carboline-3-carboxylic acid in foodstuffs, human urine and human milk
-
Adachi J, Mizoi Y, Naito T, Ogawa Y, Uetani Y, Ninomiya I (1991) Identification of tetrahydro- beta-carboline-3-carboxylic acid in foodstuffs, human urine and human milk. J Nutr 121:646-652
-
(1991)
J Nutr
, vol.121
, pp. 646-652
-
-
Adachi, J.1
Mizoi, Y.2
Naito, T.3
Ogawa, Y.4
Uetani, Y.5
Ninomiya, I.6
-
2
-
-
0019776320
-
Beta-carbolines, psychoactive compounds in the mammalian body. 2. Effects
-
Airaksinen MM, Kari I (1981a) Beta-carbolines, psychoactive compounds in the mammalian body. 2. Effects. Med Biol 59:190-211
-
(1981)
Med Biol
, vol.59
, pp. 190-211
-
-
Airaksinen, M.M.1
Kari, I.2
-
3
-
-
0019406904
-
Beta-Carbolines, psychoactive compounds in the mammalian body. Occurrence, origin and metabolism
-
Airaksinen MM, Kari I (1981b) Beta-Carbolines, psychoactive compounds in the mammalian body. Occurrence, origin and metabolism. Med Biol 59:21-34
-
(1981)
Med Biol
, vol.59
, pp. 21-34
-
-
Airaksinen, M.M.1
Kari, I.2
-
4
-
-
5444224997
-
1-Trichloromethyl--1,2,3,4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH
-
Akundi RS, Macho A, Munoz E, Lieb K, Bringmann G, Clement HW, Hull M, Fiebich BL (2004) 1-Trichloromethyl--1,2,3,4-tetrahydro-beta-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH. J Neurochem 91:263-273
-
(2004)
J Neurochem
, vol.91
, pp. 263-273
-
-
Akundi, R.S.1
Macho, A.2
Munoz, E.3
Lieb, K.4
Bringmann, G.5
Clement, H.W.6
Hull, M.7
Fiebich, B.L.8
-
5
-
-
0025688141
-
Mitochondrial respiratory inhibition by A-methylated beta-carboline derivatives structurally resembling N-methyl-4- phenylpyridine
-
Albores R, Neafsey EJ, Drucker G, Fields JZ, Collins MA (1990) Mitochondrial respiratory inhibition by A-methylated beta-carboline derivatives structurally resembling N-methyl-4- phenylpyridine. Proc Natl Acad Sci USA 87:9368-9372
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 9368-9372
-
-
Albores, R.1
Neafsey, E.J.2
Drucker, G.3
Fields, J.Z.4
Collins, M.A.5
-
6
-
-
31844443441
-
In vitro and ex vivo distribution of H-3 harmane, an endogenous beta-carboline, in rat brain
-
Anderson NJ, Tyacke RJ, Husbands SM, Nutt DJ, Hudson AL, Robinson ESJ (2006) In vitro and ex vivo distribution of H-3 harmane, an endogenous beta-carboline, in rat brain. Neuropharmacology 50:269-276
-
(2006)
Neuropharmacology
, vol.50
, pp. 269-276
-
-
Anderson, N.J.1
Tyacke, R.J.2
Husbands, S.M.3
Nutt, D.J.4
Hudson, A.L.5
Robinson, E.S.J.6
-
7
-
-
0033791071
-
A-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: Nicotinamide loading test
-
Aoyama K, Matsubara K, Okada K, Fukushima S, Shimizu K, Yamaguchi S, Uezono T, Satomi M, Hayase N, Ohta S, Shiono H, Kobayashi S (2000) A-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test. J Neural Transm 107:985-995
-
(2000)
J Neural Transm
, vol.107
, pp. 985-995
-
-
Aoyama, K.1
Matsubara, K.2
Okada, K.3
Fukushima, S.4
Shimizu, K.5
Yamaguchi, S.6
Uezono, T.7
Satomi, M.8
Hayase, N.9
Ohta, S.10
Shiono, H.11
Kobayashi, S.12
-
8
-
-
0019377920
-
Identification and quantification of 1,2,3,4-tetrahydro-beta-carboline, 2-methyl-1,2,3,4-tetrahydro-beta-carboline, and 6-methoxy-1,2,3,4-tetrahydro-beta-carboline as in vivo constituents of rat brain and adrenal gland
-
Barker SA, Harrison REW, Monti JA, Brown GB, Christian ST (1981) Identification and quantification of 1,2,3,4-tetrahydro-beta-carboline, 2-methyl-1,2,3,4-tetrahydro-beta-carboline, and 6-methoxy-1,2,3,4-tetrahydro-beta-carboline as in vivo constituents of rat brain and adrenal gland. Biochem Pharmacol 30:9-17
-
(1981)
Biochem Pharmacol
, vol.30
, pp. 9-17
-
-
Barker, S.A.1
Harrison, R.E.W.2
Monti, J.A.3
Brown, G.B.4
Christian, S.T.5
-
9
-
-
0022778249
-
6-Hydroxymethtryptoline is naturally-occurring in mammalian urine. Identification by combined chiral capillary gas chromatography and high resolution mass spectrometry
-
Beck O, Repke DB, Faull KF (1986) 6-Hydroxymethtryptoline is naturally-occurring in mammalian urine. Identification by combined chiral capillary gas chromatography and high resolution mass spectrometry. Biomed Environ Mass Spectrom 13:469-472
-
(1986)
Biomed Environ Mass Spectrom
, vol.13
, pp. 469-472
-
-
Beck, O.1
Repke, D.B.2
Faull, K.F.3
-
10
-
-
3242703231
-
The strong inhibition of triosephos- phate isomerase by the natural beta-carbolines may explain their neurotoxic actions
-
Bonnet R, Pavlovic S, Lehmann J, Rommelspacher H (2004) The strong inhibition of triosephos- phate isomerase by the natural beta-carbolines may explain their neurotoxic actions. Neuroscience 127:443-453
-
(2004)
Neuroscience
, vol.127
, pp. 443-453
-
-
Bonnet, R.1
Pavlovic, S.2
Lehmann, J.3
Rommelspacher, H.4
-
11
-
-
0030582743
-
Endogenous alkaloids in man.26. Determination of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in biological samples using gas chromatography with selected ion monitoring
-
Bringmann G, Friedrich H, Birner G, Koob M, Sontag KH, Heim C, Kolasiewicz W, Fahr S, Stablein M, God R, Feineis D (1996) Endogenous alkaloids in man.26. Determination of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in biological samples using gas chromatography with selected ion monitoring. J Chromatogr B 687:337-348
-
(1996)
J Chromatogr B
, vol.687
, pp. 337-348
-
-
Bringmann, G.1
Friedrich, H.2
Birner, G.3
Koob, M.4
Sontag, K.H.5
Heim, C.6
Kolasiewicz, W.7
Fahr, S.8
Stablein, M.9
God, R.10
Feineis, D.11
-
12
-
-
0036238704
-
1-Trichloromethyl--1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: Chemistry and biochemical effects on catecholamine biosynthesis
-
Bringmann G, Feineis D, God R, Peters K, Peters EM, Scholz J, Riederer F, Moser A (2002) 1-Trichloromethyl--1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: Chemistry and biochemical effects on catecholamine biosynthesis. Bioorg Med Chem 10:2207-2214
-
(2002)
Bioorg Med Chem
, vol.10
, pp. 2207-2214
-
-
Bringmann, G.1
Feineis, D.2
God, R.3
Peters, K.4
Peters, E.M.5
Scholz, J.6
Riederer, F.7
Moser, A.8
-
13
-
-
33748578965
-
Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4- tetrahydro-beta-carboline (TaClo) in PC12 cells
-
Bringmann G, Feineis D, Munchbach M, God R, Peters K, Peters EM, Mossner R, Lesch KP (2006) Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4- tetrahydro-beta-carboline (TaClo) in PC12 cells. Z Naturforsch C 61:601-610
-
(2006)
Z Naturforsch C
, vol.61
, pp. 601-610
-
-
Bringmann, G.1
Feineis, D.2
Munchbach, M.3
God, R.4
Peters, K.5
Peters, E.M.6
Mossner, R.7
Lesch, K.P.8
-
14
-
-
0019196690
-
Neurobiology of tetrahydro-beta-carbolines
-
Buckholtz NS (1980) Neurobiology of tetrahydro-beta-carbolines. Life Sci 27:893-903
-
(1980)
Life Sci
, vol.27
, pp. 893-903
-
-
Buckholtz, N.S.1
-
15
-
-
0028176878
-
Differential cytotoxicities of A-methyl-beta- carbolinium analogs of MPP+ in PC12 cells. Insights into potential neurotoxicants in Parkinson's disease
-
Cobuzzi RJ, Neafsey EJ, Collins MA (1994) Differential cytotoxicities of A-methyl-beta- carbolinium analogs of MPP+ in PC12 cells. Insights into potential neurotoxicants in Parkinson's disease. J Neurochem 62:1503-1510
-
(1994)
J Neurochem
, vol.62
, pp. 1503-1510
-
-
Cobuzzi, R.J.1
Neafsey, E.J.2
Collins, M.A.3
-
16
-
-
0030436624
-
1-Methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) is A-demethylated by cytochromes P450 2D6, 1A2 and 3A4. Implications for susceptibility to Parkinson's disease
-
Coleman T, Ellis SW, Martin IJ, Lennard MS, Tucker GT (1996) 1-Methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) is A-demethylated by cytochromes P450 2D6, 1A2 and 3A4. Implications for susceptibility to Parkinson's disease. J Pharmacol Exp Ther 277:685-690
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 685-690
-
-
Coleman, T.1
Ellis, S.W.2
Martin, I.J.3
Lennard, M.S.4
Tucker, G.T.5
-
17
-
-
0021992979
-
Beta-Carboline analogs of A-methyl-4-phenyl-1,2,5,6- tetrahydropyridine (MPTP). Endogenous factors underlying idiopathic Parkinsonism
-
Collins MA, Neafsey EJ (1985) Beta-Carboline analogs of A-methyl-4-phenyl-1,2,5,6- tetrahydropyridine (MPTP). Endogenous factors underlying idiopathic Parkinsonism. Neurosci Lett 55:179-184
-
(1985)
Neurosci Lett
, vol.55
, pp. 179-184
-
-
Collins, M.A.1
Neafsey, E.J.2
-
18
-
-
0001857332
-
Beta-carboline derivatives as neurotoxins
-
Moser EA (ed) Birkhauser, Boston
-
Collins MA, Neafsey EJ (1998) Beta-carboline derivatives as neurotoxins. In: Moser EA (ed) Pharmacology of endogenous neurotoxins. Birkhauser, Boston, pp 129-149
-
(1998)
Pharmacology of endogenous neurotoxins
, pp. 129-149
-
-
Collins, M.A.1
Neafsey, E.J.2
-
19
-
-
0026500661
-
Indole-A-methylated beta- carbolinium ions as potential brain bioactivated neurotoxins
-
Collins MA, Neafsey EJ, Matsubara K, Cobuzzi RJ, Rollema H (1992) Indole-A-methylated beta- carbolinium ions as potential brain bioactivated neurotoxins. Brain Res 570:154-160
-
(1992)
Brain Res
, vol.570
, pp. 154-160
-
-
Collins, M.A.1
Neafsey, E.J.2
Matsubara, K.3
Cobuzzi, R.J.4
Rollema, H.5
-
22
-
-
0025101783
-
Dopamine uptake inhibitory capacities of beta-carboline and 3,4-dihydro-beta-carboline analogs of A-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) oxidation products
-
Drucker G, Raikoff K, Neafsey EJ, Collins MA (1990) Dopamine uptake inhibitory capacities of beta-carboline and 3,4-dihydro-beta-carboline analogs of A-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) oxidation products. Brain Res 509:125-133
-
(1990)
Brain Res
, vol.509
, pp. 125-133
-
-
Drucker, G.1
Raikoff, K.2
Neafsey, E.J.3
Collins, M.A.4
-
23
-
-
77957885625
-
Harman induces CYP1A1 enzyme through an aryl hydrocarbon receptor mechanism
-
El Gendy MAM, El-Kadi AUS (2010) Harman induces CYP1A1 enzyme through an aryl hydrocarbon receptor mechanism. Toxicol Appl Pharmacol 249:55-64
-
(2010)
Toxicol Appl Pharmacol
, vol.249
, pp. 55-64
-
-
El Gendy, M.A.M.1
El-Kadi, A.U.S.2
-
24
-
-
1442329302
-
CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease
-
Elbaz A, Levecque C, Clavel J, Vidal JS, Richard F, Amouyel P, Alperovitch A, Chartier-Harlin MC, Tzourio C (2004) CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease. Ann Neurol 55:430-434
-
(2004)
Ann Neurol
, vol.55
, pp. 430-434
-
-
Elbaz, A.1
Levecque, C.2
Clavel, J.3
Vidal, J.S.4
Richard, F.5
Amouyel, P.6
Alperovitch, A.7
Chartier-Harlin, M.C.8
Tzourio, C.9
-
25
-
-
0027406992
-
Effects of harmane (1-Methyl-beta-carboline) on neurons in the nucleus accumbens of the rat
-
Ergene E, Schoener EP (1993) Effects of harmane (1-Methyl-beta-carboline) on neurons in the nucleus accumbens of the rat. Pharmacol Biochem Behav 44:951-957
-
(1993)
Pharmacol Biochem Behav
, vol.44
, pp. 951-957
-
-
Ergene, E.1
Schoener, E.P.2
-
26
-
-
0027235317
-
Occurrence and partition of the beta-carboline norharman in rat organs
-
Fekkes D, Bode WT (1993) Occurrence and partition of the beta-carboline norharman in rat organs. Life Sci 52:2045-2054
-
(1993)
Life Sci
, vol.52
, pp. 2045-2054
-
-
Fekkes, D.1
Bode, W.T.2
-
27
-
-
0026540868
-
Norharman, a normal body constituent
-
Fekkes D, Schouten MJ, Pepplinkhuizen L, Bruinvels J, Lauwers W, Brinkman UA (1992) Norharman, a normal body constituent. Lancet 339:506
-
(1992)
Lancet
, vol.339
, pp. 506
-
-
Fekkes, D.1
Schouten, M.J.2
Pepplinkhuizen, L.3
Bruinvels, J.4
Lauwers, W.5
Brinkman, U.A.6
-
28
-
-
0026567650
-
1-Methyl-tetrahydro-beta-carboline-3- carboxylic acid is present in the rat brain and is not increased after acute ethanol injection with cyanamide treatment
-
Fukushima S, Matsubara K, Akane A, Shiono H (1992) 1-Methyl-tetrahydro-beta-carboline-3- carboxylic acid is present in the rat brain and is not increased after acute ethanol injection with cyanamide treatment. Alcohol 9:31-35
-
(1992)
Alcohol
, vol.9
, pp. 31-35
-
-
Fukushima, S.1
Matsubara, K.2
Akane, A.3
Shiono, H.4
-
29
-
-
0031027976
-
Characterization of brain beta-carboline-2-A-meth- yltransferase, an enzyme that may play a role in idiopathic Parkinson's disease
-
Gearhart DA, Neafsey EJ, Collins MA (1997) Characterization of brain beta-carboline-2-A-meth- yltransferase, an enzyme that may play a role in idiopathic Parkinson's disease. Neurochem Res 22:113-121
-
(1997)
Neurochem Res
, vol.22
, pp. 113-121
-
-
Gearhart, D.A.1
Neafsey, E.J.2
Collins, M.A.3
-
30
-
-
0034210323
-
Increased beta-carboline 9A-methyltransferase activity in the frontal cortex in Parkinson's disease
-
Gearhart DA, Collins MA, Lee JM, Neafsey EJ (2000) Increased beta-carboline 9A-methyltransferase activity in the frontal cortex in Parkinson's disease. Neurobiol Dis 7:201-211
-
(2000)
Neurobiol Dis
, vol.7
, pp. 201-211
-
-
Gearhart, D.A.1
Collins, M.A.2
Lee, J.M.3
Neafsey, E.J.4
-
31
-
-
0036126554
-
Phenylethanolarnine A-methyltransferase has beta- carboline 2A-methyltransferase activity: Hypothetical relevance to Parkinson's disease
-
Gearhart DA, Neafsey EJ, Collins MA (2002a) Phenylethanolarnine A-methyltransferase has beta- carboline 2A-methyltransferase activity: hypothetical relevance to Parkinson's disease. Neurochem Int 40:611-620
-
(2002)
Neurochem Int
, vol.40
, pp. 611-620
-
-
Gearhart, D.A.1
Neafsey, E.J.2
Collins, M.A.3
-
32
-
-
0036876618
-
Identification of brain proteins that interact with 2-methylnorharman: An analog of the parkinsonian-inducing toxin, MPP+
-
Gearhart DA, Toole PF, Beach JW (2002b) Identification of brain proteins that interact with 2-methylnorharman: An analog of the parkinsonian-inducing toxin, MPP+. Neurosci Res 44:255-265
-
(2002)
Neurosci Res
, vol.44
, pp. 255-265
-
-
Gearhart, D.A.1
Toole, P.F.2
Beach, J.W.3
-
33
-
-
0001630515
-
HPLC-MS/MS profiling of tryptophan-derived alkaloids in food: Identification of tetrahydro-beta-carbolinedicarboxylic acids
-
Gutsche B, Herderich M (1997) HPLC-MS/MS profiling of tryptophan-derived alkaloids in food: Identification of tetrahydro-beta-carbolinedicarboxylic acids. J Agric Food Chem 45:2458-2462
-
(1997)
J Agric Food Chem
, vol.45
, pp. 2458-2462
-
-
Gutsche, B.1
Herderich, M.2
-
35
-
-
33746398090
-
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture
-
Hamann J, Rommelspacher H, Storch A, Reichmann H, Gille G (2006) Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture. J Neurochem 98:1185-1199
-
(2006)
J Neurochem
, vol.98
, pp. 1185-1199
-
-
Hamann, J.1
Rommelspacher, H.2
Storch, A.3
Reichmann, H.4
Gille, G.5
-
36
-
-
38349135366
-
9-Methyl- beta-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic culture
-
Hamann J, Wernicke C, Lehmann J, Reichmann H, Rommelspacher H, Gille G (2008) 9-Methyl- beta-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic culture. Neurochem Int 52:688-700
-
(2008)
Neurochem Int
, vol.52
, pp. 688-700
-
-
Hamann, J.1
Wernicke, C.2
Lehmann, J.3
Reichmann, H.4
Rommelspacher, H.5
Gille, G.6
-
37
-
-
0021224694
-
Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
-
Heikkila RE, Manzino L, Cabbat FS, Duvoisin RC (1984) Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature 311:467-469
-
(1984)
Nature
, vol.311
, pp. 467-469
-
-
Heikkila, R.E.1
Manzino, L.2
Cabbat, F.S.3
Duvoisin, R.C.4
-
38
-
-
0001739560
-
Occurrence of tetrahydro-beta-carboline-3-carboxylic acids in commercial foodstuffs
-
Herraiz T (1996) Occurrence of tetrahydro-beta-carboline-3-carboxylic acids in commercial foodstuffs. J Agric Food Chem 44:3057-3065
-
(1996)
J Agric Food Chem
, vol.44
, pp. 3057-3065
-
-
Herraiz, T.1
-
39
-
-
0036667324
-
Identification and occurrence of the bioactive beta-carbolines norharman and harman in coffee brews
-
Herraiz T (2002) Identification and occurrence of the bioactive beta-carbolines norharman and harman in coffee brews. Food Addit Contam 19:748-754
-
(2002)
Food Addit Contam
, vol.19
, pp. 748-754
-
-
Herraiz, T.1
-
40
-
-
11944275594
-
Relative exposure to beta-carbolines norharman and harman from foods and tobacco smoke
-
Herraiz T (2004a) Relative exposure to beta-carbolines norharman and harman from foods and tobacco smoke. Food Addit Contam 21:1041-1050
-
(2004)
Food Addit Contam
, vol.21
, pp. 1041-1050
-
-
Herraiz, T.1
-
41
-
-
30544447525
-
Tetrahydro-beta-carboline alkaloids in beverages and foods
-
Herraiz T (2004b) Tetrahydro-beta-carboline alkaloids in beverages and foods. ACS Symp Ser 871:405-426
-
(2004)
ACS Symp Ser
, vol.871
, pp. 405-426
-
-
Herraiz, T.1
-
42
-
-
35548939870
-
Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO)
-
Herraiz T (2007) Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO). J Agric Food Chem 55:8534-8540
-
(2007)
J Agric Food Chem
, vol.55
, pp. 8534-8540
-
-
Herraiz, T.1
-
43
-
-
84906228822
-
Beta-carboline alkaloids
-
Gilbert J, enyuva HZ (eds) Blackwell, Oxford
-
Herraiz T (2008) Beta-carboline alkaloids. In: Gilbert J, enyuva HZ (eds) Bioactive compounds in foods. Blackwell, Oxford, pp 199-218
-
(2008)
Bioactive compounds in foods
, pp. 199-218
-
-
Herraiz, T.1
-
44
-
-
9944263390
-
Human monoamine oxidase is inhibited by tobacco smoke: Beta- carboline alkaloids act as potent and reversible inhibitors
-
Herraiz T, Chaparro C (2005) Human monoamine oxidase is inhibited by tobacco smoke: beta- carboline alkaloids act as potent and reversible inhibitors. Biochem Biophys Res Commun 326:378-386
-
(2005)
Biochem Biophys Res Commun
, vol.326
, pp. 378-386
-
-
Herraiz, T.1
Chaparro, C.2
-
45
-
-
30544432396
-
Human monoamine oxidase enzyme inhibition by coffee and beta- carbolines norharman and harman isolated from coffee
-
Herraiz T, Chaparro C (2006) Human monoamine oxidase enzyme inhibition by coffee and beta- carbolines norharman and harman isolated from coffee. Life Sci 78:795-802
-
(2006)
Life Sci
, vol.78
, pp. 795-802
-
-
Herraiz, T.1
Chaparro, C.2
-
46
-
-
0242691743
-
Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers
-
Herraiz T, Galisteo J (2003) Tetrahydro-beta-carboline alkaloids occur in fruits and fruit juices. Activity as antioxidants and radical scavengers. J Agric Food Chem 51:7156-7161
-
(2003)
J Agric Food Chem
, vol.51
, pp. 7156-7161
-
-
Herraiz, T.1
Galisteo, J.2
-
47
-
-
1342347654
-
Endogenous and dietary indoles: A class of antioxidants and radical scavengers in the ABTS assay
-
Herraiz T, Galisteo J (2004) Endogenous and dietary indoles: A class of antioxidants and radical scavengers in the ABTS assay. Free Radic Res 38:323-331
-
(2004)
Free Radic Res
, vol.38
, pp. 323-331
-
-
Herraiz, T.1
Galisteo, J.2
-
48
-
-
2342527245
-
Identification and occurrence of tryptamine- and tryptophan- derived tetrahydro-beta-carbolines in commercial sausages
-
Herraiz T, Papavergou E (2004) Identification and occurrence of tryptamine- and tryptophan- derived tetrahydro-beta-carbolines in commercial sausages. J Agric Food Chem 52:2652-2658
-
(2004)
J Agric Food Chem
, vol.52
, pp. 2652-2658
-
-
Herraiz, T.1
Papavergou, E.2
-
49
-
-
33750079907
-
Comparative aromatic hydroxylation and A-demethylation of MPTP neurotoxin and its analogs, A-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6
-
Herraiz T, Guillén H, Arán VJ, Idle JR, Gonzalez FJ (2006) Comparative aromatic hydroxylation and A-demethylation of MPTP neurotoxin and its analogs, A-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6. Toxicol Appl Pharmacol 216:387-398
-
(2006)
Toxicol Appl Pharmacol
, vol.216
, pp. 387-398
-
-
Herraiz, T.1
Guillén, H.2
Arán, V.J.3
Idle, J.R.4
Gonzalez, F.J.5
-
50
-
-
33947141371
-
A-methyltetrahydro-beta-carboline analogs of 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbo- linium cations by heme peroxidases
-
Herraiz T, Guillén H, Galisteo J (2007) A-methyltetrahydro-beta-carboline analogs of 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbo- linium cations by heme peroxidases. Biochem Biophys Res Commun 356:118-123
-
(2007)
Biochem Biophys Res Commun
, vol.356
, pp. 118-123
-
-
Herraiz, T.1
Guillén, H.2
Galisteo, J.3
-
51
-
-
57449102342
-
Oxidative metabolism of the bioactive and naturally occurring beta-carboline alkaloids, norharman and harman, by human cytochrome P450 enzymes
-
Herraiz T, Guillén H, Arán VJ (2008) Oxidative metabolism of the bioactive and naturally occurring beta-carboline alkaloids, norharman and harman, by human cytochrome P450 enzymes. Chem Res Toxicol 21:2172-2180
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 2172-2180
-
-
Herraiz, T.1
Guillén, H.2
Arán, V.J.3
-
52
-
-
70450228608
-
Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO)
-
Herraiz T, Arán VJ, Guillén H (2009) Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO). Free Radic Res 43:975-984
-
(2009)
Free Radic Res
, vol.43
, pp. 975-984
-
-
Herraiz, T.1
Arán, V.J.2
Guillén, H.3
-
53
-
-
76749127951
-
Beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO)
-
Heiraiz T, Gonzalez D, Ancín-Azpilicueta C, Arán VJ, Guillén H (2010) Beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). Food Chem Toxicol 48:839-845
-
(2010)
Food Chem Toxicol
, vol.48
, pp. 839-845
-
-
Heiraiz, T.1
Gonzalez, D.2
Ancín-Azpilicueta, C.3
Arán, V.J.4
Guillén, H.5
-
54
-
-
0018220321
-
Tetrahydronorharmane (Tetrahydro-beta-carboline), a physiologically occurring compound of indole metabolism
-
Honecker H, Rommelspacher H (1978) Tetrahydronorharmane (Tetrahydro-beta-carboline), a physiologically occurring compound of indole metabolism. Naunyn Schmiedebergs Arch Pharmacol 305:135-141
-
(1978)
Naunyn Schmiedebergs Arch Pharmacol
, vol.305
, pp. 135-141
-
-
Honecker, H.1
Rommelspacher, H.2
-
55
-
-
0029414754
-
1-Trichloromethyl-1,2,3,4-tetrahydro- beta-carboline, a new inhibitor of complex I
-
Janetzky B, God R, Bringmann G, Reichmann H (1995) 1-Trichloromethyl-1,2,3,4-tetrahydro- beta-carboline, a new inhibitor of complex I. J Neural Transm Suppl 46:265-273
-
(1995)
J Neural Transm Suppl
, vol.46
, pp. 265-273
-
-
Janetzky, B.1
God, R.2
Bringmann, G.3
Reichmann, H.4
-
56
-
-
0028973103
-
Plasma levels of the beta-car- bolines harman and norharman in Parkinson's disease
-
Kuhn W, Muller T, Grosse H, Dierks T, Rommelspacher H (1995a) Plasma levels of the beta-car- bolines harman and norharman in Parkinson's disease. Acta Neurol Scand 92:451-454
-
(1995)
Acta Neurol Scand
, vol.92
, pp. 451-454
-
-
Kuhn, W.1
Muller, T.2
Grosse, H.3
Dierks, T.4
Rommelspacher, H.5
-
58
-
-
0030462474
-
Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients
-
Kuhn W, Muller T, Grosse H, Rommelspacher H (1996) Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients. J Neural Transm 103:1435-1440
-
(1996)
J Neural Transm
, vol.103
, pp. 1435-1440
-
-
Kuhn, W.1
Muller, T.2
Grosse, H.3
Rommelspacher, H.4
-
59
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219:979-980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
60
-
-
0343081001
-
Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells
-
Lee CS, Han ES, Jang YY, Han JH, Ha HW, Kim DE (2000) Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells. J Neurochem 75:521-531
-
(2000)
J Neurochem
, vol.75
, pp. 521-531
-
-
Lee, C.S.1
Han, E.S.2
Jang, Y.Y.3
Han, J.H.4
Ha, H.W.5
Kim, D.E.6
-
61
-
-
0031984973
-
Investigation on plasma levels of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta- carboline after oral administration of chloral hydrate in man
-
Leuschner J, Beuscher N, Zimmermann T, Schurer M, Schulz HU, Jeromin J, Ritter H (1998) Investigation on plasma levels of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-beta- carboline after oral administration of chloral hydrate in man. Arzneimittelforschung 48:1-5
-
(1998)
Arzneimittelforschung
, vol.48
, pp. 1-5
-
-
Leuschner, J.1
Beuscher, N.2
Zimmermann, T.3
Schurer, M.4
Schulz, H.U.5
Jeromin, J.6
Ritter, H.7
-
62
-
-
33748313157
-
Parkinson's disease-like syndrome in rats induced by 2,9-dim- ethyl-beta-carbolinium ion, a beta-carboline occurring in the human brain
-
Lorenc-Koci E, Rommelspacher H, Schulze G, Wernicke C, Kuter K, Smialowska M, Wieronska J, Zieba B, Ossowska K (2006) Parkinson's disease-like syndrome in rats induced by 2,9-dim- ethyl-beta-carbolinium ion, a beta-carboline occurring in the human brain. Behav Pharmacol 17:463-473
-
(2006)
Behav Pharmacol
, vol.17
, pp. 463-473
-
-
Lorenc-Koci, E.1
Rommelspacher, H.2
Schulze, G.3
Wernicke, C.4
Kuter, K.5
Smialowska, M.6
Wieronska, J.7
Zieba, B.8
Ossowska, K.9
-
63
-
-
0037168771
-
Elevation of blood beta-carboline alkaloids in essential tremor
-
Louis ED, Zheng W, Jurewicz EC, Watner D, Chen J, Factor-Litvak P, Parides M (2002) Elevation of blood beta-carboline alkaloids in essential tremor. Neurology 59:1940-1944
-
(2002)
Neurology
, vol.59
, pp. 1940-1944
-
-
Louis, E.D.1
Zheng, W.2
Jurewicz, E.C.3
Watner, D.4
Chen, J.5
Factor-Litvak, P.6
Parides, M.7
-
64
-
-
0030218738
-
Age-related accumulation of 1-methyl-1,2,3,4- tetrahydro-beta-carboline-3-carboxylic acid in human lens
-
Manabe S, Yuan J, Takahashi T, Urban RC (1996) Age-related accumulation of 1-methyl-1,2,3,4- tetrahydro-beta-carboline-3-carboxylic acid in human lens. Exp Eye Res 63:179-186
-
(1996)
Exp Eye Res
, vol.63
, pp. 179-186
-
-
Manabe, S.1
Yuan, J.2
Takahashi, T.3
Urban, R.C.4
-
65
-
-
77950419280
-
Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4- phenylpyridinium toxicity in SH-SY5Y neuronal cells
-
Mann A, Tyndale RF (2010) Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4- phenylpyridinium toxicity in SH-SY5Y neuronal cells. Eur J Neurosci 31:1185-1193
-
(2010)
Eur J Neurosci
, vol.31
, pp. 1185-1193
-
-
Mann, A.1
Tyndale, R.F.2
-
66
-
-
54049130764
-
Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment
-
Mann A, Miksys S, Lee A, Mash DC, Tyndale RF (2008) Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment. Neuropharmacology 55:1147-1155
-
(2008)
Neuropharmacology
, vol.55
, pp. 1147-1155
-
-
Mann, A.1
Miksys, S.2
Lee, A.3
Mash, D.C.4
Tyndale, R.F.5
-
67
-
-
0345602167
-
Overexpression of CYP2D6 attenuates the toxicity of MPP+ in actively dividing and differentiated PC12 cells
-
Matoh N, Tanaka S, Takehashi M, Banasik M, Stedeford T, Masliah E, Suzuki S, Nishimura Y, Ueda K (2003) Overexpression of CYP2D6 attenuates the toxicity of MPP+ in actively dividing and differentiated PC12 cells. Gene Expr 11:117-124
-
(2003)
Gene Expr
, vol.11
, pp. 117-124
-
-
Matoh, N.1
Tanaka, S.2
Takehashi, M.3
Banasik, M.4
Stedeford, T.5
Masliah, E.6
Suzuki, S.7
Nishimura, Y.8
Ueda, K.9
-
68
-
-
0026764244
-
Mono-A-methylation of 1,2,3,4-tetrahydro- beta- carbolines in brain cytosol. Absence of indole methylation
-
Matsubara K, Collins MA, Neafsey EJ (1992a) Mono-A-methylation of 1,2,3,4-tetrahydro- beta- carbolines in brain cytosol. Absence of indole methylation. J Neurochem 59:505-510
-
(1992)
J Neurochem
, vol.59
, pp. 505-510
-
-
Matsubara, K.1
Collins, M.A.2
Neafsey, E.J.3
-
69
-
-
0026777955
-
Novel S-adenosylmethionine-dependent indole-A- methylation of beta-carbolines in brain particulate fractions
-
Matsubara K, Neafsey EJ, Collins MA (1992b) Novel S-adenosylmethionine-dependent indole-A- methylation of beta-carbolines in brain particulate fractions. J Neurochem 59:511-518
-
(1992)
J Neurochem
, vol.59
, pp. 511-518
-
-
Matsubara, K.1
Neafsey, E.J.2
Collins, M.A.3
-
70
-
-
0027252719
-
Potential bioactivated neurotoxicants, A-methylated beta-carbolinium ions, are present in human brain
-
Matsubara K, Collins MA, Akane A, Ikebuchi J, Neafsey EJ, Kagawa M, Shiono H (1993) Potential bioactivated neurotoxicants, A-methylated beta-carbolinium ions, are present in human brain. Brain Res 610:90-96
-
(1993)
Brain Res
, vol.610
, pp. 90-96
-
-
Matsubara, K.1
Collins, M.A.2
Akane, A.3
Ikebuchi, J.4
Neafsey, E.J.5
Kagawa, M.6
Shiono, H.7
-
71
-
-
0029440852
-
Beta-carbolinium cations, endogenous MPP+ analogs, in the lumbar cerebrospinal fluid of patients with Parkinson's disease
-
Matsubara K, Kobayashi S, Kobayashi Y, Yamashita K, Koide H, Hatta M, Iwamoto K, Tanaka O, Kimura K (1995) Beta-carbolinium cations, endogenous MPP+ analogs, in the lumbar cerebrospinal fluid of patients with Parkinson's disease. Neurology 45:2240-2245
-
(1995)
Neurology
, vol.45
, pp. 2240-2245
-
-
Matsubara, K.1
Kobayashi, S.2
Kobayashi, Y.3
Yamashita, K.4
Koide, H.5
Hatta, M.6
Iwamoto, K.7
Tanaka, O.8
Kimura, K.9
-
72
-
-
0031952527
-
Endogenously occurring beta-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease
-
Matsubara K, Gonda T, Sawada H, Uezono T, Kobayashi Y, Kawamura T, Ohtaki K, Kimura K, Akaike A (1998a) Endogenously occurring beta-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease. J Neurochem 70:727-735
-
(1998)
J Neurochem
, vol.70
, pp. 727-735
-
-
Matsubara, K.1
Gonda, T.2
Sawada, H.3
Uezono, T.4
Kobayashi, Y.5
Kawamura, T.6
Ohtaki, K.7
Kimura, K.8
Akaike, A.9
-
73
-
-
0032077861
-
Structural significance of azaheterocyclic amines related to Parkinson's disease for dopamine transporter
-
Matsubara K, Senda T, Uezono T, Fukushima S, Ohta S, Igarashi K, Naoi M, Yamashita Y, Ohtaki K, Hayase N, Akutsu S, Kimura K (1998b) Structural significance of azaheterocyclic amines related to Parkinson's disease for dopamine transporter. Eur J Pharmacol 348:77-84
-
(1998)
Eur J Pharmacol
, vol.348
, pp. 77-84
-
-
Matsubara, K.1
Senda, T.2
Uezono, T.3
Fukushima, S.4
Ohta, S.5
Igarashi, K.6
Naoi, M.7
Yamashita, Y.8
Ohtaki, K.9
Hayase, N.10
Akutsu, S.11
Kimura, K.12
-
74
-
-
0035917904
-
L-deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP+ and beta-carbolinium: A microdialysis study in rats
-
Matsubara K, Senda T, Uezono T, Awaya T, Ogawa S, Chiba K, Shimizu K, Hayase N, Kimura K (2001) L-deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP+ and beta-carbolinium: a microdialysis study in rats. Neurosci Lett 302:65-68
-
(2001)
Neurosci Lett
, vol.302
, pp. 65-68
-
-
Matsubara, K.1
Senda, T.2
Uezono, T.3
Awaya, T.4
Ogawa, S.5
Chiba, K.6
Shimizu, K.7
Hayase, N.8
Kimura, K.9
-
76
-
-
0030606816
-
Formaldehyde-derived tetrahy- droisoquinolines and tetrahydro-beta-carbolines in human urine
-
Musshoff F, Daldrup T, Bonte W, Leitner A, Lesch OM (1996) Formaldehyde-derived tetrahy- droisoquinolines and tetrahydro-beta-carbolines in human urine. J Chromatogr B 683:163-176
-
(1996)
J Chromatogr B
, vol.683
, pp. 163-176
-
-
Musshoff, F.1
Daldrup, T.2
Bonte, W.3
Leitner, A.4
Lesch, O.M.5
-
77
-
-
0024446756
-
Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a beta-carbolinium analog of N-methyl-4- phenylpyridinium ion (MPP+)
-
Neafsey EJ, Drucker G, Raikoff K, Collins MA (1989) Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a beta-carbolinium analog of N-methyl-4- phenylpyridinium ion (MPP+). Neurosci Lett 105:344-349
-
(1989)
Neurosci Lett
, vol.105
, pp. 344-349
-
-
Neafsey, E.J.1
Drucker, G.2
Raikoff, K.3
Collins, M.A.4
-
79
-
-
1442265714
-
Long-term retention of neurotoxic beta-carbolines in brain neuromelanin
-
Östergren A, Annas A, Skog K, Lindquist NG, Brittebo EB (2004) Long-term retention of neurotoxic beta-carbolines in brain neuromelanin. J Neural Transm 111:141-157
-
(2004)
J Neural Transm
, vol.111
, pp. 141-157
-
-
Östergren, A.1
Annas, A.2
Skog, K.3
Lindquist, N.G.4
Brittebo, E.B.5
-
80
-
-
32044468501
-
Norharman-induced motoric impairment in mice: Neurodegeneration and glial activation in substantia nigra
-
Östergren A, Fredriksson A, Brittebo EB (2006) Norharman-induced motoric impairment in mice: neurodegeneration and glial activation in substantia nigra. J Neural Transm 113:313-329
-
(2006)
J Neural Transm
, vol.113
, pp. 313-329
-
-
Östergren, A.1
Fredriksson, A.2
Brittebo, E.B.3
-
81
-
-
34347362938
-
Differential effects of dopamine melanin on nor- harman-induced toxicity in PC12 cells
-
Östergren A, Lindquist NG, Brittebo EB (2007) Differential effects of dopamine melanin on nor- harman-induced toxicity in PC12 cells. J Neural Transm 114:909-918
-
(2007)
J Neural Transm
, vol.114
, pp. 909-918
-
-
Östergren, A.1
Lindquist, N.G.2
Brittebo, E.B.3
-
82
-
-
19944410141
-
Harmane and harmalan are bioactive components of classical clonidine-displacing substance
-
Parker CA, Anderson NJ, Robinson ESJ, Price R, Tyacke RJ, Husbands SM, Dillon MP, Eglen RM, Hudson AL, Nutt DJ, Crump MP, Crosby J (2004) Harmane and harmalan are bioactive components of classical clonidine-displacing substance. Biochemistry 43:16385-16392
-
(2004)
Biochemistry
, vol.43
, pp. 16385-16392
-
-
Parker, C.A.1
Anderson, N.J.2
Robinson, E.S.J.3
Price, R.4
Tyacke, R.J.5
Husbands, S.M.6
Dillon, M.P.7
Eglen, R.M.8
Hudson, A.L.9
Nutt, D.J.10
Crump, M.P.11
Crosby, J.12
-
83
-
-
0037448075
-
High expression of nicotinamide A-methyltransferase in patients with idiopathic Parkinson's disease
-
Parsons RB, Smith SW, Waring RH, Williams AC, Ramsden DB (2003) High expression of nicotinamide A-methyltransferase in patients with idiopathic Parkinson's disease. Neurosci Lett 342:13-16
-
(2003)
Neurosci Lett
, vol.342
, pp. 13-16
-
-
Parsons, R.B.1
Smith, S.W.2
Waring, R.H.3
Williams, A.C.4
Ramsden, D.B.5
-
84
-
-
33646137553
-
2,9-Dimethyl-beta-carbolinium, a neurotoxin occurring in human brain, is a potent inducer of apoptosis as 1-methyl-4-phenylpyridinium
-
Pavlovic S, Schulze G, Wernicke C, Bonnet R, Gille G, Badiali L, Kaminska A, Lorenc-Koci E, Ossowska K, Rommelspacher H (2006) 2,9-Dimethyl-beta-carbolinium, a neurotoxin occurring in human brain, is a potent inducer of apoptosis as 1-methyl-4-phenylpyridinium. Neuroscience 139:1525-1537
-
(2006)
Neuroscience
, vol.139
, pp. 1525-1537
-
-
Pavlovic, S.1
Schulze, G.2
Wernicke, C.3
Bonnet, R.4
Gille, G.5
Badiali, L.6
Kaminska, A.7
Lorenc-Koci, E.8
Ossowska, K.9
Rommelspacher, H.10
-
85
-
-
0022445973
-
Paraquat and two endogenous analogs of the neurotoxic substance A-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse
-
Perry TL, Yong VW, Wall RA, Jones K (1986) Paraquat and two endogenous analogs of the neurotoxic substance A-methyl-4-phenyl-1,2,3,6-tetrahydropyridine do not damage dopaminergic nigrostriatal neurons in the mouse. Neurosci Lett 69:285-289
-
(1986)
Neurosci Lett
, vol.69
, pp. 285-289
-
-
Perry, T.L.1
Yong, V.W.2
Wall, R.A.3
Jones, K.4
-
86
-
-
1242351299
-
Exposure to beta-carbolines norharman and harman
-
Pfau W, Skog K (2004) Exposure to beta-carbolines norharman and harman. J Chromatogr B 802:115-126
-
(2004)
J Chromatogr B
, vol.802
, pp. 115-126
-
-
Pfau, W.1
Skog, K.2
-
87
-
-
0037713489
-
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model. A tool to explore the pathogenesis of Parkinson's disease
-
Przedborski S, Vila M (2003) The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model. A tool to explore the pathogenesis of Parkinson's disease. Ann N Y Acad Sci 991:189-198
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 189-198
-
-
Przedborski, S.1
Vila, M.2
-
89
-
-
0037012733
-
Biochemical and pharmacological characterization of 1-trichloromethyl -1,2,3,4-tetrahydro-beta-carboline: A biologically relevant neurotoxin
-
Riederer P, Foley P, Bringmann G, Feineis D, Bruckner R, Gerlach M (2002) Biochemical and pharmacological characterization of 1-trichloromethyl -1,2,3,4-tetrahydro-beta-carboline: a biologically relevant neurotoxin? Eur J Pharmacol 442:1-16
-
(2002)
Eur J Pharmacol
, vol.442
, pp. 1-16
-
-
Riederer, P.1
Foley, P.2
Bringmann, G.3
Feineis, D.4
Bruckner, R.5
Gerlach, M.6
-
90
-
-
1342284213
-
Endogenous beta-carbolines as clonidine-displacing substances
-
Robinson ESJ, Anderson NJ, Crosby J, Nutt DJ, Hudson AL (2003) Endogenous beta-carbolines as clonidine-displacing substances. Ann N Y Acad Sci 1009:157-166
-
(2003)
Ann N Y Acad Sci
, vol.1009
, pp. 157-166
-
-
Robinson, E.S.J.1
Anderson, N.J.2
Crosby, J.3
Nutt, D.J.4
Hudson, A.L.5
-
91
-
-
0023695241
-
In vivo dopaminergic neurotoxicity of the 2-beta- methylcarbolinium ion, a potential endogenous MPP+ analog
-
Rollema H, Booth RG, Castagnoli N (1988) In vivo dopaminergic neurotoxicity of the 2-beta- methylcarbolinium ion, a potential endogenous MPP+ analog. Eur J Pharmacol 153:131-134
-
(1988)
Eur J Pharmacol
, vol.153
, pp. 131-134
-
-
Rollema, H.1
Booth, R.G.2
Castagnoli, N.3
-
92
-
-
85037064053
-
Biochemical and pharmacological studies with 6-hydroxytetrahydronorharmane (6-OH-tetrahydro-beta-carboline), a physiologically occurring metabolite of 5-hydroxytryptamine
-
Rommelspacher H, Honecker H, Meinke B (1979) Biochemical and pharmacological studies with 6-hydroxytetrahydronorharmane (6-OH-tetrahydro-beta-carboline), a physiologically occurring metabolite of 5-hydroxytryptamine. Naunyn Schmiedebergs Arch Pharmacol 307:R65
-
(1979)
Naunyn Schmiedebergs Arch Pharmacol
, vol.307
, pp. R65
-
-
Rommelspacher, H.1
Honecker, H.2
Meinke, B.3
-
93
-
-
0019153736
-
Excretion of tetrahydroharmane and harmane into the urine of man and rat after a load with ethanol
-
Rommelspacher H, Strauss S, Lindemann J (1980) Excretion of tetrahydroharmane and harmane into the urine of man and rat after a load with ethanol. FEBS Lett 109:209-212
-
(1980)
FEBS Lett
, vol.109
, pp. 209-212
-
-
Rommelspacher, H.1
Strauss, S.2
Lindemann, J.3
-
94
-
-
0026315884
-
Beta-Carbolines and tetrahydroisoquinolines: Detection and function in mammals
-
Rommelspacher H, May T, Susilo R (1991a) Beta-Carbolines and tetrahydroisoquinolines: Detection and function in mammals. Planta Med 57:S85-S92
-
(1991)
Planta Med
, vol.57
, pp. S85-S92
-
-
Rommelspacher, H.1
May, T.2
Susilo, R.3
-
95
-
-
0025826430
-
Plasma norharman (beta-carboline) levels are elevated in chronic alcoholics
-
Rommelspacher H, Schmidt LG, May T (1991b) Plasma norharman (beta-carboline) levels are elevated in chronic alcoholics. Alcohol Clin Exp Res 15:553-559
-
(1991)
Alcohol Clin Exp Res
, vol.15
, pp. 553-559
-
-
Rommelspacher, H.1
Schmidt, L.G.2
May, T.3
-
96
-
-
0028103733
-
Harman (1-methyl-beta-carboline) is a natural inhibitor of monoamine oxidase type-A in rats
-
Rommelspacher H, May T, Salewski B (1994) Harman (1-methyl-beta-carboline) is a natural inhibitor of monoamine oxidase type-A in rats. Eur J Pharmacol 252:51-59
-
(1994)
Eur J Pharmacol
, vol.252
, pp. 51-59
-
-
Rommelspacher, H.1
May, T.2
Salewski, B.3
-
97
-
-
0037134292
-
The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets
-
Rommelspacher H, Meier-Henco M, Smolka M, Kloft C (2002) The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets. Eur J Pharmacol 441:115-125
-
(2002)
Eur J Pharmacol
, vol.441
, pp. 115-125
-
-
Rommelspacher, H.1
Meier-Henco, M.2
Smolka, M.3
Kloft, C.4
-
98
-
-
0030600524
-
Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats
-
Sällström Baum S, Hill R, Rommelspacher H (1996) Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats. Eur J Pharmacol 314:75-82
-
(1996)
Eur J Pharmacol
, vol.314
, pp. 75-82
-
-
Sällström Baum, S.1
Hill, R.2
Rommelspacher, H.3
-
99
-
-
33749362966
-
6-Hydroxy- and 6-methoxy-beta-car- bolines as acetyl- and butyrylcholinesterase inhibitors
-
Schott Y, Decker M, Rommelspacher H, Lehmann J (2006) 6-Hydroxy- and 6-methoxy-beta-car- bolines as acetyl- and butyrylcholinesterase inhibitors. Bioorg Med Chem Lett 16:5840-5843
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 5840-5843
-
-
Schott, Y.1
Decker, M.2
Rommelspacher, H.3
Lehmann, J.4
-
100
-
-
0036151973
-
The impact of smoking and drinking on plasma levels of norharman
-
Spijkerman R, van den Eijnden R, van de Mheen D, Bongers I, Fekkes D (2002) The impact of smoking and drinking on plasma levels of norharman. Eur Neuropsychopharmacol 12:61-71
-
(2002)
Eur Neuropsychopharmacol
, vol.12
, pp. 61-71
-
-
Spijkerman, R.1
van den Eijnden, R.2
van de Mheen, D.3
Bongers, I.4
Fekkes, D.5
-
101
-
-
2042423928
-
Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: Relationship to transporter-dependent uptake
-
Storch A, Hwang YI, Gearhart DA, Beach JW, Neafsey EJ, Collins MA, Schwarz J (2004a) Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake. J Neurochem 89:685-694
-
(2004)
J Neurochem
, vol.89
, pp. 685-694
-
-
Storch, A.1
Hwang, Y.I.2
Gearhart, D.A.3
Beach, J.W.4
Neafsey, E.J.5
Collins, M.A.6
Schwarz, J.7
-
102
-
-
7944227203
-
Dopamine transporter: Involvement in selective dopaminergic neurotoxicity and degeneration
-
Storch A, Ludolph AC, Schwarz J (2004b) Dopamine transporter: involvement in selective dopaminergic neurotoxicity and degeneration. J Neural Transm 111:1267-1286
-
(2004)
J Neural Transm
, vol.111
, pp. 1267-1286
-
-
Storch, A.1
Ludolph, A.C.2
Schwarz, J.3
-
103
-
-
33750991907
-
Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells
-
Storch A, Hwang YI, Bringmann G, Feineis D, Ott S, Bruckner R, Schwarz J (2006) Cytotoxicity of chloral-derived beta-carbolines is not specific towards neuronal nor dopaminergic cells. J Neural Transm 113:1895-1901
-
(2006)
J Neural Transm
, vol.113
, pp. 1895-1901
-
-
Storch, A.1
Hwang, Y.I.2
Bringmann, G.3
Feineis, D.4
Ott, S.5
Bruckner, R.6
Schwarz, J.7
-
104
-
-
0031784056
-
Structural determination of a mutagenic aminophenylnorharman produced by the co-mutagen norharman with aniline
-
Totsuka Y, Hada N, Matsumoto K, Kawahara N, Murakami Y, Yokoyama Y, Sugimura T, Wakabayashi K (1998) Structural determination of a mutagenic aminophenylnorharman produced by the co-mutagen norharman with aniline. Carcinogenesis 19:1995-2000
-
(1998)
Carcinogenesis
, vol.19
, pp. 1995-2000
-
-
Totsuka, Y.1
Hada, N.2
Matsumoto, K.3
Kawahara, N.4
Murakami, Y.5
Yokoyama, Y.6
Sugimura, T.7
Wakabayashi, K.8
-
105
-
-
0028302788
-
Quantitation of urinary-1,2,3,4- tetrahydro-beta-carboline and 1-methyl-1,2,3,4-tetrahydro-ß-carboline by high performance liquid chromatography
-
Tsuchiya H, Ohtani S, Yamada K, Takagi N, Todoriki H, Hayashi T (1994) Quantitation of urinary-1,2,3,4- tetrahydro-beta-carboline and 1-methyl-1,2,3,4-tetrahydro-ß-carboline by high performance liquid chromatography. J Pharm Sci 83:415-418
-
(1994)
J Pharm Sci
, vol.83
, pp. 415-418
-
-
Tsuchiya, H.1
Ohtani, S.2
Yamada, K.3
Takagi, N.4
Todoriki, H.5
Hayashi, T.6
-
106
-
-
34548119850
-
Cytotoxicity of beta-carbolines in dopamine transporter expressing cells: Structure-activity relationships
-
Wernicke C, Schott Y, Enzensperger C, Schulze G, Lehmann J, Rommelspacher H (2007) Cytotoxicity of beta-carbolines in dopamine transporter expressing cells: Structure-activity relationships. Biochem Pharmacol 74:1065-1077
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1065-1077
-
-
Wernicke, C.1
Schott, Y.2
Enzensperger, C.3
Schulze, G.4
Lehmann, J.5
Rommelspacher, H.6
-
107
-
-
77950828019
-
9-Methyl-beta-carboline has restorative effects in an animal model of Parkinson's disease
-
Wernicke C, Hellmann J, Zieba B, Kuter K, Ossowska K, Frenzel M, Dencher NA, Rommelspacher H (2010) 9-Methyl-beta-carboline has restorative effects in an animal model of Parkinson's disease. Pharmacol Rep 62:35-53
-
(2010)
Pharmacol Rep
, vol.62
, pp. 35-53
-
-
Wernicke, C.1
Hellmann, J.2
Zieba, B.3
Kuter, K.4
Ossowska, K.5
Frenzel, M.6
Dencher, N.A.7
Rommelspacher, H.8
-
108
-
-
69549105760
-
The harman and norharman reduced dopamine content and induced cytotoxicity in PC12 cells
-
Yang YJ, Lim SC, Lee MK (2008) The harman and norharman reduced dopamine content and induced cytotoxicity in PC12 cells. Biomol Ther 16:106-112
-
(2008)
Biomol Ther
, vol.16
, pp. 106-112
-
-
Yang, Y.J.1
Lim, S.C.2
Lee, M.K.3
-
109
-
-
0038240578
-
Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase
-
Yu AM, Idle JR, Herraiz T, Küpfer A, Gonzalez FJ (2003a) Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase. Pharmacogenetics 13:307-319
-
(2003)
Pharmacogenetics
, vol.13
, pp. 307-319
-
-
Yu, A.M.1
Idle, J.R.2
Herraiz, T.3
Küpfer, A.4
Gonzalez, F.J.5
-
110
-
-
0037381219
-
Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine
-
Yu AM, Idle JR, Krausz KW, Küpfer A, Gonzalez FJ (2003b) Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine. J Pharmacol Exp Ther 305:315-322
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 315-322
-
-
Yu, A.M.1
Idle, J.R.2
Krausz, K.W.3
Küpfer, A.4
Gonzalez, F.J.5
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