-
1
-
-
5444224997
-
1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH
-
Akundi R. S., Macho A., Muñoz E., Lieb K., Bringmann G., Clement H. W., Hüll M., and Fiebich B. L. (2004), 1-Trichloromethyl-1,2,3,4- tetrahydro-β-carboline-induced apoptosis in the human neuroblastoma cell line SK-N-SH. J. Neurochem. 91, 263-273.
-
(2004)
J. Neurochem.
, vol.91
, pp. 263-273
-
-
Akundi, R.S.1
Macho, A.2
Muñoz, E.3
Lieb, K.4
Bringmann, G.5
Clement, H.W.6
Hüll, M.7
Fiebich, B.L.8
-
2
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V., and Greenamyre T. (2000), Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature Neurosci. 3, 1301-1306.
-
(2000)
Nature Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, T.6
-
3
-
-
0025490465
-
1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline - A potential chloral-derived indol alkaloid in man
-
Bringmann G. and Hille A. (1990), 1-Trichloromethyl-1,2,3,4-tetrahydro- β-carboline - a potential chloral-derived indol alkaloid in man. Arch. Pharm. 323, 567-569.
-
(1990)
Arch. Pharm.
, vol.323
, pp. 567-569
-
-
Bringmann, G.1
Hille, A.2
-
4
-
-
0000272948
-
Highly halogenated tetrahydro-β-carbolines as a new class of dopaminergic neurotoxins
-
(Moser A., ed.). Birkhäuser, Boston, Basel, Berlin
-
Bringmann G., Feineis D., Grote C., God R., Clement H. W., Sontag K. H., Janetzky B., Reichmann H., Rausch W. D., Riederer P., and Wesemann W. (1998), Highly halogenated tetrahydro-β-carbolines as a new class of dopaminergic neurotoxins. In: Pharmacology of Endogenous Neurotoxins - A Handbook (Moser A., ed.). Birkhäuser, Boston, Basel, Berlin, pp. 151-169.
-
(1998)
Pharmacology of Endogenous Neurotoxins - A Handbook
, pp. 151-169
-
-
Bringmann, G.1
Feineis, D.2
Grote, C.3
God, R.4
Clement, H.W.5
Sontag, K.H.6
Janetzky, B.7
Reichmann, H.8
Rausch, W.D.9
Riederer, P.10
Wesemann, W.11
-
5
-
-
0033562588
-
Identification of the dopaminergic neurotoxin 1-trichloromethyl-1,2,3,4- tetrahydro-β-carboline in human blood after intake of the hypnotic chloral hydrate
-
Bringmann G., God R., Fähr S., Feineis D., Fornadi K., and Fornadi F. (1999), Identification of the dopaminergic neurotoxin 1-trichloromethyl-1,2, 3,4-tetrahydro-β-carboline in human blood after intake of the hypnotic chloral hydrate. Anal. Biochem. 270, 167-175.
-
(1999)
Anal. Biochem.
, vol.270
, pp. 167-175
-
-
Bringmann, G.1
God, R.2
Fähr, S.3
Feineis, D.4
Fornadi, K.5
Fornadi, F.6
-
6
-
-
0001348832
-
'TaClo', a chloral-derived mammalian alkaloid with neurotoxic properties
-
(Storch A. and Collins M. A., eds.). Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow
-
Bringmann G., Bruckner R., Munchbach M., Feineis D., God R., Wesemann W., Grote C., Herderich M., Diem S., Lesch K. P., Mössner R., and Storch A. (2000a), 'TaClo', a chloral-derived mammalian alkaloid with neurotoxic properties. In: Neurotoxic Factors in Parkinson's Disease and Related Disorders (Storch A. and Collins M. A., eds.). Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow, pp. 145-149.
-
(2000)
Neurotoxic Factors in Parkinson's Disease and Related Disorders
, pp. 145-149
-
-
Bringmann, G.1
Bruckner, R.2
Munchbach, M.3
Feineis, D.4
God, R.5
Wesemann, W.6
Grote, C.7
Herderich, M.8
Diem, S.9
Lesch, K.P.10
Mössner, R.11
Storch, A.12
-
7
-
-
18744422932
-
Bromal-derived tetrahydro-β-carbolines as neurotoxic agents: Chemistry, impairment of the dopamine metabolism, and inhibitory effects on mitochondrial respiration
-
Bringmann G., Feineis D., Bruckner R., Blank M., Peters K., Peters E. M., Reichmann H., Janetzky B., Grote C., Clement H. W., and Wesemann W. (2000b), Bromal-derived tetrahydro-β-carbolines as neurotoxic agents: chemistry, impairment of the dopamine metabolism, and inhibitory effects on mitochondrial respiration. Bioorg. Med. Chem. 8, 1467-1478.
-
(2000)
Bioorg. Med. Chem.
, vol.8
, pp. 1467-1478
-
-
Bringmann, G.1
Feineis, D.2
Bruckner, R.3
Blank, M.4
Peters, K.5
Peters, E.M.6
Reichmann, H.7
Janetzky, B.8
Grote, C.9
Clement, H.W.10
Wesemann, W.11
-
8
-
-
0035907135
-
Studies on single-strand scissions to cell-free plasmid DNA by the dopaminergic neurotoxin 'TaClo' (1-trichloromethyl-1,2,3,4-tetrahydro-β- carboline)
-
Bringmann G., Münchbach M., Feineis D., Faulhaber K., and Ihmels H. (2001), Studies on single-strand scissions to cell-free plasmid DNA by the dopaminergic neurotoxin 'TaClo' (1-trichloromethyl-1,2,3,4-tetrahydro-β- carboline). Neurosci. Lett. 304, 41-44.
-
(2001)
Neurosci. Lett.
, vol.304
, pp. 41-44
-
-
Bringmann, G.1
Münchbach, M.2
Feineis, D.3
Faulhaber, K.4
Ihmels, H.5
-
9
-
-
0036164205
-
Chiral" and "achiral" determination of the neurotoxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline) from blood and urine samples by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry
-
Bringmann G., Münchbach M., Feineis D., Messer K., Diem S., Herderich M., Clement H. W., Stichel-Gunkel C., and Kuhn W. (2002), "Chiral" and "achiral" determination of the neurotoxin TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline) from blood and urine samples by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr. B 767, 321-332.
-
(2002)
J. Chromatogr. B
, vol.767
, pp. 321-332
-
-
Bringmann, G.1
Münchbach, M.2
Feineis, D.3
Messer, K.4
Diem, S.5
Herderich, M.6
Clement, H.W.7
Stichel-Gunkel, C.8
Kuhn, W.9
-
10
-
-
33745847131
-
Synthesis of radiolabelled 1-trichloromethyl-1,2,3,4-tetrahydro-β- carboline (TaClo), a neurotoxic chloral-derived mammalian alkaloid, and its biodistribution in rats
-
Bringmann G., Feineis D., Brückner R., God R., Grote C., and Wesemann W. (2006), Synthesis of radiolabelled 1-trichloromethyl-1,2,3,4- tetrahydro-β-carboline (TaClo), a neurotoxic chloral-derived mammalian alkaloid, and its biodistribution in rats. Eur. J. Pharm. Sci. 28, 412-422.
-
(2006)
Eur. J. Pharm. Sci.
, vol.28
, pp. 412-422
-
-
Bringmann, G.1
Feineis, D.2
Brückner, R.3
God, R.4
Grote, C.5
Wesemann, W.6
-
11
-
-
0001798577
-
+ as environmental neurotoxins
-
(Storch A. and Collins M. A., eds.). Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow
-
+ as environmental neurotoxins. In: Neurotoxic Factors in Parkinson's Disease and Related Disorders (Storch A. and Collins M. A., eds.). Kluwer Academic/Plenum Publishers, New York, Boston, Dordrecht, London, Moscow, pp. 115-130.
-
(2000)
Neurotoxic Factors in Parkinson's Disease and Related Disorders
, pp. 115-130
-
-
Collins, M.A.1
Neafsey, E.J.2
-
12
-
-
0032553465
-
1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats
-
Gerlach M., Xiao A. Y., Heim C., Lan J., God R., Feineis D., Bringman G., Riederer P., and Sontag K. H. (1998), 1-Trichloromethyl-1,2,3,4-tetrahydro- β-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats. Neurosci. Lett. 257, 17-20.
-
(1998)
Neurosci. Lett.
, vol.257
, pp. 17-20
-
-
Gerlach, M.1
Xiao, A.Y.2
Heim, C.3
Lan, J.4
God, R.5
Feineis, D.6
Bringman, G.7
Riederer, P.8
Sontag, K.H.9
-
13
-
-
0032696108
-
Occupational metal exposures and the risk of Parkinson's disease
-
Gorell J. M., Rybicki B. A., Cole Johnson C., and Peterson E. L. (1999), Occupational metal exposures and the risk of Parkinson's disease. Neuroepidemiology 18, 303-308.
-
(1999)
Neuroepidemiology
, vol.18
, pp. 303-308
-
-
Gorell, J.M.1
Rybicki, B.A.2
Cole Johnson, C.3
Peterson, E.L.4
-
14
-
-
0030940898
-
High-performance liquid chromatography-electrospray tandem mass spectrometry (HPLC-ESI-MS/MS) for the analysis of 1,2,3,4-tetrahydro-β- carboline derivatives
-
Gutsche B. and Herderich M. (1997) High-performance liquid chromatography-electrospray tandem mass spectrometry (HPLC-ESI-MS/MS) for the analysis of 1,2,3,4-tetrahydro-β-carboline derivatives. J. Chromatogr. A 767, 101-106.
-
(1997)
J. Chromatogr. A
, vol.767
, pp. 101-106
-
-
Gutsche, B.1
Herderich, M.2
-
15
-
-
84975751684
-
Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
-
Hartley A., Stone J. M., Heron C., Cooper J. M., and Schapira A. H. V. (1994), Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J. Neurochem. 63, 1987-1990.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1987-1990
-
-
Hartley, A.1
Stone, J.M.2
Heron, C.3
Cooper, J.M.4
Schapira, A.H.V.5
-
16
-
-
0032952497
-
Effects of highly halogenated β-carbolines on dopaminergic cells in culture and mitochondrial respiration
-
Janetzky B., Gille G., Abdel-mohsen M., God R., Rausch W. D., Bringmann G., and Reichmann H. (1999), Effects of highly halogenated β-carbolines on dopaminergic cells in culture and mitochondrial respiration. Drug Dev. Res. 46, 51-56.
-
(1999)
Drug Dev. Res.
, vol.46
, pp. 51-56
-
-
Janetzky, B.1
Gille, G.2
Abdel-mohsen, M.3
God, R.4
Rausch, W.D.5
Bringmann, G.6
Reichmann, H.7
-
18
-
-
1042279505
-
The endogenous formation of highly chlorinated tetrahydro-β- carbolines as a possible causative mechanism in idiopathic Parkinson's disease
-
Kochen W., Kohlmüller D., De Biasi P, and Ramsay R. (2003), The endogenous formation of highly chlorinated tetrahydro-β-carbolines as a possible causative mechanism in idiopathic Parkinson's disease. Adv. Exp. Med. Biol. 527, 253-263.
-
(2003)
Adv. Exp. Med. Biol.
, vol.527
, pp. 253-263
-
-
Kochen, W.1
Kohlmüller, D.2
De Biasi, P.3
Ramsay, R.4
-
19
-
-
0031952527
-
Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease
-
Matsubara K., Gonda T., Sawada H., Uezono T., Kobayashi Y., Kawamura T., Ohtaki K. I., Kimura K., and Akaike A. (1998), Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: a possible causative protoxin in idiopathic Parkinson's disease. J. Neurochem. 70, 727-735.
-
(1998)
J. Neurochem.
, vol.70
, pp. 727-735
-
-
Matsubara, K.1
Gonda, T.2
Sawada, H.3
Uezono, T.4
Kobayashi, Y.5
Kawamura, T.6
Ohtaki, K.I.7
Kimura, K.8
Akaike, A.9
-
20
-
-
0031693023
-
Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease
-
McNaught K. St. P., Carrupt P. A., Altomare C., Cellamare S., Carotti A., Testa B., Jenner P., and Marsden C. D. (1998), Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease. Biochem. Pharmacol. 56, 921-933.
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 921-933
-
-
McNaught, K.St.P.1
Carrupt, P.A.2
Altomare, C.3
Cellamare, S.4
Carotti, A.5
Testa, B.6
Jenner, P.7
Marsden, C.D.8
-
21
-
-
0036717067
-
Dopamine-derived endogenous N-methyl-(R)-salsolinol: Its role in Parkinson's disease
-
Naoi M., Maruyama W., Akao Y., and Yi H. (2002), Dopamine-derived endogenous N-methyl-(R)-salsolinol: its role in Parkinson's disease. Neurotoxicol. Teratol. 24, 579-591.
-
(2002)
Neurotoxicol. Teratol.
, vol.24
, pp. 579-591
-
-
Naoi, M.1
Maruyama, W.2
Akao, Y.3
Yi, H.4
-
22
-
-
0342659924
-
2-Trifluoroacetyl-1-methyl-1,2,3,4-tetrahydro-β-carboline, a gaschromatographically useful derivative of the mammalian alkaloid eleagnine
-
Peters K., Peters E.-M., von Schnering H. G., Bringmann G., and God R. (1995), 2-Trifluoroacetyl-1-methyl-1,2,3,4-tetrahydro-β-carboline, a gaschromatographically useful derivative of the mammalian alkaloid eleagnine. Z. Naturforsch. 50b, 1564-1565.
-
(1995)
Z. Naturforsch.
, vol.50 B
, pp. 1564-1565
-
-
Peters, K.1
Peters, E.-M.2
Von Schnering, H.G.3
Bringmann, G.4
God, R.5
-
23
-
-
0019490679
-
Syntheses and spectral data of some 1-alkyl-substituted 1,2,3,4-tetrahydro-β-carbolines
-
Peura P. and Nousiainen E. (1981), Syntheses and spectral data of some 1-alkyl-substituted 1,2,3,4-tetrahydro-β-carbolines. Acta Pharm. Fenn. 90, 75-178.
-
(1981)
Acta Pharm. Fenn.
, vol.90
, pp. 75-178
-
-
Peura, P.1
Nousiainen, E.2
-
24
-
-
0033811231
-
Hydrocarbon exposure and Parkinson's disease
-
Pezzoli G., Canesi M., Antonini A., Righini A., Perbellini L., Barichella M., Mariani C. B., Tenconi F., Tesei S., Zecchinelli A., and Leenders K. L. (2000), Hydrocarbon exposure and Parkinson's disease. Neurology 55, 667-673.
-
(2000)
Neurology
, vol.55
, pp. 667-673
-
-
Pezzoli, G.1
Canesi, M.2
Antonini, A.3
Righini, A.4
Perbellini, L.5
Barichella, M.6
Mariani, C.B.7
Tenconi, F.8
Tesei, S.9
Zecchinelli, A.10
Leenders, K.L.11
-
25
-
-
0001485756
-
MPTP: A review of its mechanisms of neurotoxicity
-
Przedborski S. and Vila M. (2001), MPTP: a review of its mechanisms of neurotoxicity. Clin. Neurosci. Res. 1, 407-418.
-
(2001)
Clin. Neurosci. Res.
, vol.1
, pp. 407-418
-
-
Przedborski, S.1
Vila, M.2
-
26
-
-
0037012733
-
Biochemical and pharmacological characterization of 1-trichloromethyl-1, 2,3,4-tetrahydro-β-carboline: A biologically relevant neurotoxin?
-
Riederer P., Foley P., Bringmann G., Feineis D., Brückner R., and Gerlach M. (2002), Biochemical and pharmacological characterization of 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline: a biologically relevant neurotoxin? Eur. J. Pharmacol. 442, 1-16.
-
(2002)
Eur. J. Pharmacol.
, vol.442
, pp. 1-16
-
-
Riederer, P.1
Foley, P.2
Bringmann, G.3
Feineis, D.4
Brückner, R.5
Gerlach, M.6
-
27
-
-
0013529428
-
-
Siemens Analytical X-Ray Instruments Inc., Madison, Wisconsin, USA
-
Sheldrick G. M. (1997), Program Package SHELXL-97, Release 4.1. Siemens Analytical X-Ray Instruments Inc., Madison, Wisconsin, USA.
-
(1997)
Program Package SHELXL-97, Release 4.1
-
-
Sheldrick, G.M.1
-
28
-
-
0006078746
-
-
Analytical X-Ray Instruments Inc., Madison, Wisconsin, USA
-
Siemens (1996), P4 X-Ray Program System. Analytical X-Ray Instruments Inc., Madison, Wisconsin, USA.
-
(1996)
P4 X-Ray Program System
-
-
|