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Volumn 215, Issue 1, 2010, Pages 136-140

Long term exposure to norharman exacerbates 6-hydroxydopamine-induced parkinsonism: Possible involvement of L-type Ca2+ channels

Author keywords

6 OHDA; BCs; Behavioral symptoms; Nifedipine; Norharman; Parkinson's disease

Indexed keywords

BETA CARBOLINE; CALCIUM CHANNEL L TYPE; NIFEDIPINE; OXIDOPAMINE;

EID: 77955846667     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.07.011     Document Type: Article
Times cited : (15)

References (35)
  • 1
    • 0030472746 scopus 로고    scopus 로고
    • Action of harman 1-methyl-b-carboline on the brain: body temperature and in vivo efflux of 5-HT from hippocampus of the rat
    • Adell A., Biggs T.A., Myers R.D. Action of harman 1-methyl-b-carboline on the brain: body temperature and in vivo efflux of 5-HT from hippocampus of the rat. Neuropharmacology 1996, 35:1101-1107.
    • (1996) Neuropharmacology , vol.35 , pp. 1101-1107
    • Adell, A.1    Biggs, T.A.2    Myers, R.D.3
  • 2
    • 0030600524 scopus 로고    scopus 로고
    • Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats
    • Baum S.S., Hill R., Rommelspacher H. Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats. Eur J Pharmacol 1996, 314:75-82.
    • (1996) Eur J Pharmacol , vol.314 , pp. 75-82
    • Baum, S.S.1    Hill, R.2    Rommelspacher, H.3
  • 3
    • 3242703231 scopus 로고    scopus 로고
    • The strong inhibition of triosephosphate isomerase by the natural-carbolines may explain their neurotoxic actions
    • Bonnet R., Pavlovic S., Lehmann J., Rommelspacher H. The strong inhibition of triosephosphate isomerase by the natural-carbolines may explain their neurotoxic actions. Neuroscience 2004, 127:443-453.
    • (2004) Neuroscience , vol.127 , pp. 443-453
    • Bonnet, R.1    Pavlovic, S.2    Lehmann, J.3    Rommelspacher, H.4
  • 4
    • 65349159205 scopus 로고    scopus 로고
    • Calcium homeostasis, selective vulnerability and Parkinson's disease
    • Chan C.S., Gertler T.S., Surmeier D.J. Calcium homeostasis, selective vulnerability and Parkinson's disease. Trends Neurosci 2009, 32(5):249-256.
    • (2009) Trends Neurosci , vol.32 , Issue.5 , pp. 249-256
    • Chan, C.S.1    Gertler, T.S.2    Surmeier, D.J.3
  • 5
    • 0026500661 scopus 로고
    • Indole-N-methylated-carbolinium ions as potential brain-bioactivated toxins
    • Collins M.A., Neafsey E.J., Matsubara K., Cobuzzi R.J., Rollema H. Indole-N-methylated-carbolinium ions as potential brain-bioactivated toxins. Brain Res 1992, 505:154-160.
    • (1992) Brain Res , vol.505 , pp. 154-160
    • Collins, M.A.1    Neafsey, E.J.2    Matsubara, K.3    Cobuzzi, R.J.4    Rollema, H.5
  • 7
    • 0036715374 scopus 로고    scopus 로고
    • Potential neurotoxic " agents provocateurs" in Parkinson's disease
    • Collins MANeafsey E.J. Potential neurotoxic " agents provocateurs" in Parkinson's disease. Neurotoxicol Teratol 2002, 24:571-577.
    • (2002) Neurotoxicol Teratol , vol.24 , pp. 571-577
    • Collins MANeafsey, E.J.1
  • 8
    • 0029971114 scopus 로고    scopus 로고
    • Expression of dopamine transporter mRNA and its binding site in fetal nigral cells transplanted into the striatum of 6-OHDA lesioned rat
    • Fujita M., Nishino H., Kumazaki M., Shimada S., Tohyama M., Nishimura T. Expression of dopamine transporter mRNA and its binding site in fetal nigral cells transplanted into the striatum of 6-OHDA lesioned rat. Mol Brain Res 1996, 39:127-136.
    • (1996) Mol Brain Res , vol.39 , pp. 127-136
    • Fujita, M.1    Nishino, H.2    Kumazaki, M.3    Shimada, S.4    Tohyama, M.5    Nishimura, T.6
  • 9
    • 33746398090 scopus 로고    scopus 로고
    • Neurotoxic mechanisms of 2,9-dimethyl-b-carbolinium ion in primary dopaminergic culture
    • Hamann J., Rommelspacher H., Storch A., Reichmann H., Gille G. Neurotoxic mechanisms of 2,9-dimethyl-b-carbolinium ion in primary dopaminergic culture. J Neurochem 2006, 98:1185-1199.
    • (2006) J Neurochem , vol.98 , pp. 1185-1199
    • Hamann, J.1    Rommelspacher, H.2    Storch, A.3    Reichmann, H.4    Gille, G.5
  • 10
    • 9944263390 scopus 로고    scopus 로고
    • Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors
    • Herraiz T., Chaparro C. Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors. Biochem Biophys Res Commun 2005, 326:378-386.
    • (2005) Biochem Biophys Res Commun , vol.326 , pp. 378-386
    • Herraiz, T.1    Chaparro, C.2
  • 11
    • 0036667324 scopus 로고    scopus 로고
    • Identification and occurrence of the bioactive betacarbolines norharman and harman in coffee brews
    • Herraiz T. Identification and occurrence of the bioactive betacarbolines norharman and harman in coffee brews. Food Addit Contam 2002, 19:748-754.
    • (2002) Food Addit Contam , vol.19 , pp. 748-754
    • Herraiz, T.1
  • 12
    • 0034969732 scopus 로고    scopus 로고
    • Protective effect of harmaline and harmalol against dopamine-and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells
    • Kim D.H., Jang Y.Y., Han E.S., Lee C.S. Protective effect of harmaline and harmalol against dopamine-and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells. Eur J Neurosci 2001, 13:1861-1872.
    • (2001) Eur J Neurosci , vol.13 , pp. 1861-1872
    • Kim, D.H.1    Jang, Y.Y.2    Han, E.S.3    Lee, C.S.4
  • 13
    • 0000242290 scopus 로고    scopus 로고
    • Differential antioxidant effects of ambroxol, rutin, glutathione and harmaline
    • Kim H.H., Jang Y.Y., Han E.S., Lee C.S. Differential antioxidant effects of ambroxol, rutin, glutathione and harmaline. J Appl Pharmacol 1999, 7:112-120.
    • (1999) J Appl Pharmacol , vol.7 , pp. 112-120
    • Kim, H.H.1    Jang, Y.Y.2    Han, E.S.3    Lee, C.S.4
  • 15
    • 0030462474 scopus 로고    scopus 로고
    • Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients
    • Kuhn W., Müller T.H., Grosse H., Rommelspacher H. Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients. J Neural Transm 1996, 103:1435-1440.
    • (1996) J Neural Transm , vol.103 , pp. 1435-1440
    • Kuhn, W.1    Müller, T.H.2    Grosse, H.3    Rommelspacher, H.4
  • 16
    • 0030601952 scopus 로고    scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level
    • Kupsch A., Sautter J., Schwarz J., Riederer P., Gerlach M., Oertel W.H. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in non-human primates is antagonized by pretreatment with nimodipine at the nigral, but not at the striatal level. Brain Res 1996, 741(1-2):185-196.
    • (1996) Brain Res , vol.741 , Issue.1-2 , pp. 185-196
    • Kupsch, A.1    Sautter, J.2    Schwarz, J.3    Riederer, P.4    Gerlach, M.5    Oertel, W.H.6
  • 17
    • 0343081001 scopus 로고    scopus 로고
    • Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells
    • Lee C.S., Han E.S., Jang Y.Y., Han J.H., Ha H.W., Kim D.E. Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells. J. Neurochem 2000, 75:521-531.
    • (2000) J. Neurochem , vol.75 , pp. 521-531
    • Lee, C.S.1    Han, E.S.2    Jang, Y.Y.3    Han, J.H.4    Ha, H.W.5    Kim, D.E.6
  • 18
    • 0021877189 scopus 로고
    • Theoretical structure-activity studies of b-carboline analogs. Requirements for benzodiazepine receptor affinity and antagonist activity
    • Loew G.H., Nienow J., Lawson J.A., Toll L., Uyeno E.T. Theoretical structure-activity studies of b-carboline analogs. Requirements for benzodiazepine receptor affinity and antagonist activity. Mol Pharmacol 1985, 28:17-31.
    • (1985) Mol Pharmacol , vol.28 , pp. 17-31
    • Loew, G.H.1    Nienow, J.2    Lawson, J.A.3    Toll, L.4    Uyeno, E.T.5
  • 19
    • 0023696152 scopus 로고
    • Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function
    • Lutes J., Lorden J.F., Beales M., Lotmans G.A. Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function. Neuropharmacology 1988, 27:849-855.
    • (1988) Neuropharmacology , vol.27 , pp. 849-855
    • Lutes, J.1    Lorden, J.F.2    Beales, M.3    Lotmans, G.A.4
  • 20
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher P., Davis J.B. The role of monoamine metabolism in oxidative glutamate toxicity. Neuroscience 1996, 16:6394-6401.
    • (1996) Neuroscience , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 22
    • 0031952527 scopus 로고    scopus 로고
    • Endogenously occurring b-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease
    • Matsubara K., Gonda T., Sawada H., Uezono T., Kobayashi Y., Kawamura T., et al. Endogenously occurring b-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease. J Neurochem 1998, 70:727-735.
    • (1998) J Neurochem , vol.70 , pp. 727-735
    • Matsubara, K.1    Gonda, T.2    Sawada, H.3    Uezono, T.4    Kobayashi, Y.5    Kawamura, T.6
  • 23
    • 0034464863 scopus 로고    scopus 로고
    • Regulatory cascades involving calmodulin-dependent protein kinases
    • Means A.R. Regulatory cascades involving calmodulin-dependent protein kinases. Mol Endocrinol 2000, 14:4-13.
    • (2000) Mol Endocrinol , vol.14 , pp. 4-13
    • Means, A.R.1
  • 24
    • 0026502219 scopus 로고
    • UV-treated lipoproteins as a model system for the study of biological effects of lipid peroxides on cultured cells
    • Negre-Salvayre A., Salvayre R. UV-treated lipoproteins as a model system for the study of biological effects of lipid peroxides on cultured cells. Biochim Biophys Acta 1992, 1123:207-215.
    • (1992) Biochim Biophys Acta , vol.1123 , pp. 207-215
    • Negre-Salvayre, A.1    Salvayre, R.2
  • 25
    • 33646137553 scopus 로고    scopus 로고
    • 2,9-Dimethyl-b-carbolinium, a neurotoxin occuring in human brain, is an equipotent apoptotic inducer as 1-methyl-4-phenylpyridinium (MPP+)
    • Pavlovic S., Schulze G., Wernicke C., Bonnet R., Gille G., Badiali L., et al. 2,9-Dimethyl-b-carbolinium, a neurotoxin occuring in human brain, is an equipotent apoptotic inducer as 1-methyl-4-phenylpyridinium (MPP+). Neuroscience 2006, 139:1525-1537.
    • (2006) Neuroscience , vol.139 , pp. 1525-1537
    • Pavlovic, S.1    Schulze, G.2    Wernicke, C.3    Bonnet, R.4    Gille, G.5    Badiali, L.6
  • 28
    • 0033044574 scopus 로고    scopus 로고
    • Can calcium antagonists provide a neuroprotective effect in Parkinson's disease?
    • Rodnitzky R.L. Can calcium antagonists provide a neuroprotective effect in Parkinson's disease?. Drugs 1999, 57(6):845-849.
    • (1999) Drugs , vol.57 , Issue.6 , pp. 845-849
    • Rodnitzky, R.L.1
  • 31
    • 2042423928 scopus 로고    scopus 로고
    • Dopamine transporter-mediated cytotoxicity of β-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake
    • Storch A., Hwang Y.-I., Gearhart D.A., Beach W., Neafsey E.J., Collins M.A., et al. Dopamine transporter-mediated cytotoxicity of β-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake. J Neurochem 2004, 89:685-694.
    • (2004) J Neurochem , vol.89 , pp. 685-694
    • Storch, A.1    Hwang, Y.-I.2    Gearhart, D.A.3    Beach, W.4    Neafsey, E.J.5    Collins, M.A.6
  • 32
    • 0018503087 scopus 로고
    • Mutagenic factors in cooked foods
    • Sugimura T., Nagao M. Mutagenic factors in cooked foods. CRC Crit Rev Toxicol 1979, 6:189-209.
    • (1979) CRC Crit Rev Toxicol , vol.6 , pp. 189-209
    • Sugimura, T.1    Nagao, M.2
  • 33
    • 34548657565 scopus 로고    scopus 로고
    • Calcium, ageing, and neuronal vulnerability in Parkinson's disease
    • Surmeier D.J. Calcium, ageing, and neuronal vulnerability in Parkinson's disease. Lancet Neurol 2007, 6(10):933-938.
    • (2007) Lancet Neurol , vol.6 , Issue.10 , pp. 933-938
    • Surmeier, D.J.1
  • 34
    • 0025912665 scopus 로고
    • Antioxidative properties of harmane and b-carboline alkaloids
    • Tse S.Y.H., Mak I.T., Dickens B.F. Antioxidative properties of harmane and b-carboline alkaloids. Biochem Pharmacol 1991, 42:459-464.
    • (1991) Biochem Pharmacol , vol.42 , pp. 459-464
    • Tse, S.Y.H.1    Mak, I.T.2    Dickens, B.F.3
  • 35
    • 13444282373 scopus 로고    scopus 로고
    • 2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells
    • 2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurosci Lett 2005, 376:127-132.
    • (2005) Neurosci Lett , vol.376 , pp. 127-132
    • Wang, X.J.1    Xu, J.X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.