Investigation on plasma levels of the neurotoxin 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline after oral administration of chloral hydrate in man;UNTERSUCHUNGEN ZU PLASMASPIEGELN DES NEUROTOXINS 1-TRICHLORMETHYL-1,2,3,4-TETRAHYDRO-β-CARBOLIN (TACLO) BEIM MENSCHEN NACH ORALER VERABREICHUNG VON CHLORALHYDRAT

Arzneimittel-Forschung/Drug Research

Volumn 48, Issue 1, 1998, Pages 1-5

  Leuschner, Jost ^a,b   Beuscher, Norbert ^a   Zimmermann, Thomas ^b   Schürer, Michael ^b   Schulz, Hans Ulrich ^c   Jeromin, Julia ^c   Ritter, Helmut ^d  

^a LPT Laboratory of Pharmacology and Toxicology   (Germany)

^b Arzt für Allgemeinmedizin   (Germany)

^c LAFAA Laboratory for Contract Research

^d UNIVERSITY OF WUPPERTAL   (Germany)

Author keywords

1 Trichloromethyl 1,2,3,4 tetrahydro carboline; CAS 302 17 0; Chloral hydrate; Chloraldurat ; Neurotoxin; TaClo

Indexed keywords

BETA CARBOLINE DERIVATIVE; CHLORAL HYDRATE; NEUROTOXIN;

ADULT; ARTICLE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG METABOLISM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION;

ADULT; CARBOLINES; CHLORAL HYDRATE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYPNOTICS AND SEDATIVES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; NEUROTOXINS; SPECTROPHOTOMETRY, INFRARED;

EID: 0031984973     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Jafaar, M., Ghulamqadir, A. K., J. Pediatr. Ophthal-mol. Strabismus 30, 372 (1993)
2. Kaur, I., Hiranandani, M., Singhi, P., Indian Pediatr. 31, 1145 (1994)
3. Napoli, K.L., Ingall, C. G., Martin, G. R., J. Pediatr. 129, 287 (1996)
4. Reeves, S. T., Wiedemfeld, K. R., Wrobleski, J. et al., J. Dent. Child. 63, 95 (1996)
5. Ronchera, C. L., Marti-Bonmati, L., Poyatos, C. et al., Pharm. Weekbl. (Sci) 14, 349 (1992)
6. Ronchera-Oms, C. L., Casillas, C., Marti-Bonmati, L. et al., J. Clin. Pharm. Ther. 19, 239 (1994)
7. Greenberg, B. S., Faeber, E. N., Aspinall, C.L. et al., Am. J. Roentgenol. 161, 639 (1993)
8. Committee on Drugs and Committee on Environmental Health, Pediatrics 92, 471 (1993)
9. Binder, L. S., Leake, L. A., Am. J. Emerg. Med. 9, 530 (1991)
10. Cavallaro, M., Am. J. EEG Technol. 33, 129 (1993)
11. Houpt, M. I., Sheskin, R. B., Koenigsberg, S. R. et al., J. Dent. Child. 52, 364 (1985)
12. Lichtenstein, R., King, J. C., Bice, D., Clin. Ped. 32, 632 (1993)
13. Lipshitz, M., Marino, B. L., Sanders, S. T., Heart Lung 22, 408 (1993)
14. Hartley, S., Franck, L. S., Lundergan, F., J. Periant. 9, 162 (1989)
15. Fachinformation Chloraldurat® 500/rot/blau, G. Pohl-Boskamp, Hohenlockstedt (1996)
16. Bringmann, G., God, R., Feineis, D. et al., J. Neural Transm. 46, 235 (1995)
17. Bringmann, G., God, R., Feineis, D. et al., J. Neural Transm. 46, 245 (1995)
18. Sontag, K.-H., Heim, C., Sontag, R. et al., J. Neural Transm. 46, 283 (1995)
19. Grote, C., Clement, H.-W., Wesemann, W. et al., J. Neural Transm. 46, 275 (1995)
20. Zimmermann, Th., Wehling, M., Schulz, H.-U., Arzneim.-Forsch./Drug Res. 48 (I), 5 (1998)
21. Andrew, R., Best, S. A., Watson, D. G. et al., Neurochem. Res. 18, 1179 (1993)