Neurotoxic mechanisms of 2,9-dimethyl-β-carbolinium ion in primary dopaminergic culture

Journal of Neurochemistry

Volumn 98, Issue 4, 2006, Pages 1185-1199

  Hamann, Juliane ^a   Rommelspacher, Hans ^b   Storch, Alexander ^a   Reichmann, Heinz ^a   Gille, Gabriele ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

carboline; 2,9 Me2NH+; Apoptosis; Dopaminergic neurones; Necrosis; Oxidative stress

Indexed keywords

2,9 DIMETHYLNORHARMAN; ADENOSINE TRIPHOSPHATE; BETA CARBOLINE; CASPASE 3; DOPAMINE TRANSPORTER; FREE RADICAL; NEUROTOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL DAMAGE; CELL MEMBRANE POTENTIAL; CELL STRUCTURE; CONTROLLED STUDY; DETERIORATION; DISEASE PREDISPOSITION; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; EMBRYO; ENZYME ACTIVITY; INCUBATION TIME; INTRACELLULAR TRANSPORT; MESENCEPHALON; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARBOLINES; CASPASE 3; CASPASES; CELL DEATH; CELL NUCLEUS; CELLS, CULTURED; DOPAMINE; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; L-LACTATE DEHYDROGENASE; LACTIC ACID; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; NECROSIS; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXICITY SYNDROMES; NITRIC OXIDE; PIPERAZINES; PREGNANCY; PYRIDINIUM COMPOUNDS; REACTIVE OXYGEN SPECIES; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 33746398090     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.03940.x     Document Type: Article

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