메뉴 건너뛰기




Volumn 123, Issue , 2017, Pages 277-302

Glycogen Synthase Kinase 3: A Kinase for All Pathways?

Author keywords

Alzheimer's; Hedgehog; Insulin; Notch; Signal transduction; TGFbeta; Wnt

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; ISOENZYME;

EID: 85009348240     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/bs.ctdb.2016.11.011     Document Type: Chapter
Times cited : (176)

References (86)
  • 1
    • 0035413614 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: Properties, functions, and regulation
    • Ali, A., Hoeflich, K.P., Woodgett, J.R., Glycogen synthase kinase-3: Properties, functions, and regulation. Chemical Reviews 101 (2001), 2527–2540.
    • (2001) Chemical Reviews , vol.101 , pp. 2527-2540
    • Ali, A.1    Hoeflich, K.P.2    Woodgett, J.R.3
  • 2
    • 79954447619 scopus 로고    scopus 로고
    • Selective loss of glycogen synthase kinase-3alpha in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation
    • Alon, L.T., Pietrokovski, S., Barkan, S., Avrahami, L., Kaidanovich-Beilin, O., Woodgett, J.R., et al. Selective loss of glycogen synthase kinase-3alpha in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation. FEBS Letters 585 (2011), 1158–1162.
    • (2011) FEBS Letters , vol.585 , pp. 1158-1162
    • Alon, L.T.1    Pietrokovski, S.2    Barkan, S.3    Avrahami, L.4    Kaidanovich-Beilin, O.5    Woodgett, J.R.6
  • 3
    • 0030035749 scopus 로고    scopus 로고
    • In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta
    • Aplin, A.E., Gibb, G.M., Jacobsen, J.S., Gallo, J.M., Anderton, B.H., In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta. Journal of Neurochemistry 67 (1996), 699–707.
    • (1996) Journal of Neurochemistry , vol.67 , pp. 699-707
    • Aplin, A.E.1    Gibb, G.M.2    Jacobsen, J.S.3    Gallo, J.M.4    Anderton, B.H.5
  • 4
    • 0035665719 scopus 로고    scopus 로고
    • The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation
    • Bax, B., Carter, P.S., Lewis, C., Guy, A.R., Bridges, A., Tanner, R., et al. The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. Structure 9 (2001), 1143–1152.
    • (2001) Structure , vol.9 , pp. 1143-1152
    • Bax, B.1    Carter, P.S.2    Lewis, C.3    Guy, A.R.4    Bridges, A.5    Tanner, R.6
  • 5
    • 0027385529 scopus 로고
    • A Saccharomyces cerevisiae protein-serine kinase related to mammalian glycogen synthase kinase-3 and the Drosophila melanogaster gene shaggy product
    • Bianchi, M.W., Plyte, S.E., Kreis, M., Woodgett, J.R., A Saccharomyces cerevisiae protein-serine kinase related to mammalian glycogen synthase kinase-3 and the Drosophila melanogaster gene shaggy product. Gene 134 (1993), 51–56.
    • (1993) Gene , vol.134 , pp. 51-56
    • Bianchi, M.W.1    Plyte, S.E.2    Kreis, M.3    Woodgett, J.R.4
  • 6
    • 0025142365 scopus 로고
    • An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2 + subfamily
    • Bourouis, M., Moore, P., Ruel, L., Grau, Y., Heitzler, P., Simpson, P., An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2 + subfamily. The EMBO Journal 9 (1990), 2877–2884.
    • (1990) The EMBO Journal , vol.9 , pp. 2877-2884
    • Bourouis, M.1    Moore, P.2    Ruel, L.3    Grau, Y.4    Heitzler, P.5    Simpson, P.6
  • 8
    • 0021064785 scopus 로고
    • ‘Insulin-like’ effects of lithium ion on isolated rat adipocytes. II. Specific activation of glycogen synthase
    • Cheng, K., Creacy, S., Larner, J., ‘Insulin-like’ effects of lithium ion on isolated rat adipocytes. II. Specific activation of glycogen synthase. Molecular and Cellular Biochemistry 56 (1983), 183–189.
    • (1983) Molecular and Cellular Biochemistry , vol.56 , pp. 183-189
    • Cheng, K.1    Creacy, S.2    Larner, J.3
  • 9
    • 0036789185 scopus 로고    scopus 로고
    • Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats
    • Cline, G.W., Johnson, K., Regittnig, W., Perret, P., Tozzo, E., Xiao, L., et al. Effects of a novel glycogen synthase kinase-3 inhibitor on insulin-stimulated glucose metabolism in Zucker diabetic fatty (fa/fa) rats. Diabetes 51 (2002), 2903–2910.
    • (2002) Diabetes , vol.51 , pp. 2903-2910
    • Cline, G.W.1    Johnson, K.2    Regittnig, W.3    Perret, P.4    Tozzo, E.5    Xiao, L.6
  • 10
    • 0033776383 scopus 로고    scopus 로고
    • Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
    • Coghlan, M.P., Culbert, A.A., Cross, D.A., Corcoran, S.L., Yates, J.W., Pearce, N.J., et al. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chemistry & Biology 7 (2000), 793–803.
    • (2000) Chemistry & Biology , vol.7 , pp. 793-803
    • Coghlan, M.P.1    Culbert, A.A.2    Cross, D.A.3    Corcoran, S.L.4    Yates, J.W.5    Pearce, N.J.6
  • 11
    • 3042635178 scopus 로고    scopus 로고
    • GSK3 inhibitors: Development and therapeutic potential
    • Cohen, P., Goedert, M., GSK3 inhibitors: Development and therapeutic potential. Nature Reviews. Drug Discovery 3 (2004), 479–487.
    • (2004) Nature Reviews. Drug Discovery , vol.3 , pp. 479-487
    • Cohen, P.1    Goedert, M.2
  • 12
    • 0020134901 scopus 로고
    • Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle
    • Cohen, P., Yellowlees, D., Aitken, A., Donella-Deana, A., Hemmings, B.A., Parker, P.J., Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle. European Journal of Biochemistry 124 (1982), 21–35.
    • (1982) European Journal of Biochemistry , vol.124 , pp. 21-35
    • Cohen, P.1    Yellowlees, D.2    Aitken, A.3    Donella-Deana, A.4    Hemmings, B.A.5    Parker, P.J.6
  • 13
    • 1642494586 scopus 로고    scopus 로고
    • Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event
    • Cole, A., Frame, S., Cohen, P., Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event. The Biochemical Journal 377 (2004), 249–255.
    • (2004) The Biochemical Journal , vol.377 , pp. 249-255
    • Cole, A.1    Frame, S.2    Cohen, P.3
  • 14
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross, D.A., Alessi, D.R., Cohen, P., Andjelkovich, M., Hemmings, B.A., Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378 (1995), 785–789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 15
    • 0037415737 scopus 로고    scopus 로고
    • Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex
    • Dajani, R., Fraser, E., Roe, S.M., Yeo, M., Good, V.M., Thompson, V., et al. Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex. The EMBO Journal 22:3 (2003), 494–501.
    • (2003) The EMBO Journal , vol.22 , Issue.3 , pp. 494-501
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3    Yeo, M.4    Good, V.M.5    Thompson, V.6
  • 16
    • 0035875098 scopus 로고    scopus 로고
    • Crystal structure of glycogen synthase kinase 3 beta: Structural basis for phosphate-primed substrate specificity and autoinhibition
    • Dajani, R., Fraser, E., Roe, S.M., Young, N., Good, V., Dale, T.C., et al. Crystal structure of glycogen synthase kinase 3 beta: Structural basis for phosphate-primed substrate specificity and autoinhibition. Cell 105:6 (2001), 721–732.
    • (2001) Cell , vol.105 , Issue.6 , pp. 721-732
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3    Young, N.4    Good, V.5    Dale, T.C.6
  • 17
    • 0036909443 scopus 로고    scopus 로고
    • Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium
    • De Sarno, P., Li, X., Jope, R.S., Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology 43:7 (2002), 1158–1164.
    • (2002) Neuropharmacology , vol.43 , Issue.7 , pp. 1158-1164
    • De Sarno, P.1    Li, X.2    Jope, R.S.3
  • 19
    • 84919678319 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-beta signaling
    • Demagny, H., Araki, T., De Robertis, E.M., The tumor suppressor Smad4/DPC4 is regulated by phosphorylations that integrate FGF, Wnt, and TGF-beta signaling. Cell Reports 9:2 (2014), 688–700.
    • (2014) Cell Reports , vol.9 , Issue.2 , pp. 688-700
    • Demagny, H.1    Araki, T.2    De Robertis, E.M.3
  • 20
    • 84939417419 scopus 로고    scopus 로고
    • Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis
    • Dembowy, J., Adissu, H.A., Liu, J.C., Zacksenhaus, E., Woodgett, J.R., Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis. Oncogene 34:27 (2015), 3514–3526.
    • (2015) Oncogene , vol.34 , Issue.27 , pp. 3514-3526
    • Dembowy, J.1    Adissu, H.A.2    Liu, J.C.3    Zacksenhaus, E.4    Woodgett, J.R.5
  • 21
    • 0028178130 scopus 로고
    • wingless acts through the shaggy/zeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg
    • Diaz-Benjumea, F.J., Cohen, S.M., wingless acts through the shaggy/zeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg. Development 120:6 (1994), 1661–1670.
    • (1994) Development , vol.120 , Issue.6 , pp. 1661-1670
    • Diaz-Benjumea, F.J.1    Cohen, S.M.2
  • 22
    • 34249311572 scopus 로고    scopus 로고
    • Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
    • Doble, B.W., Patel, S., Wood, G.A., Kockeritz, L.K., Woodgett, J.R., Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Developmental Cell 12:6 (2007), 957–971.
    • (2007) Developmental Cell , vol.12 , Issue.6 , pp. 957-971
    • Doble, B.W.1    Patel, S.2    Wood, G.A.3    Kockeritz, L.K.4    Woodgett, J.R.5
  • 25
    • 0032802629 scopus 로고    scopus 로고
    • Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice
    • Eldar-Finkelman, H., Schreyer, S.A., Shinohara, M.M., LeBoeuf, R.C., Krebs, E.G., Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice. Diabetes 48:8 (1999), 1662–1666.
    • (1999) Diabetes , vol.48 , Issue.8 , pp. 1662-1666
    • Eldar-Finkelman, H.1    Schreyer, S.A.2    Shinohara, M.M.3    LeBoeuf, R.C.4    Krebs, E.G.5
  • 26
    • 0028840004 scopus 로고
    • Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells
    • Eldar-Finkelman, H., Seger, R., Vandenheede, J.R., Krebs, E.G., Inactivation of glycogen synthase kinase-3 by epidermal growth factor is mediated by mitogen-activated protein kinase/p90 ribosomal protein S6 kinase signaling pathway in NIH/3T3 cells. The Journal of Biological Chemistry 270:3 (1995), 987–990.
    • (1995) The Journal of Biological Chemistry , vol.270 , Issue.3 , pp. 987-990
    • Eldar-Finkelman, H.1    Seger, R.2    Vandenheede, J.R.3    Krebs, E.G.4
  • 27
    • 0019026208 scopus 로고
    • Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
    • Embi, N., Rylatt, D.B., Cohen, P., Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. European Journal of Biochemistry 107:2 (1980), 519–527.
    • (1980) European Journal of Biochemistry , vol.107 , Issue.2 , pp. 519-527
    • Embi, N.1    Rylatt, D.B.2    Cohen, P.3
  • 28
    • 0041856097 scopus 로고    scopus 로고
    • Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways
    • Espinosa, L., Ingles-Esteve, J., Aguilera, C., Bigas, A., Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. The Journal of Biological Chemistry 278:34 (2003), 32227–32235.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 32227-32235
    • Espinosa, L.1    Ingles-Esteve, J.2    Aguilera, C.3    Bigas, A.4
  • 29
    • 0023656594 scopus 로고
    • Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3
    • Fiol, C.J., Mahrenholz, A.M., Wang, Y., Roeske, R.W., Roach, P.J., Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3. The Journal of Biological Chemistry 262:29 (1987), 14042–14048.
    • (1987) The Journal of Biological Chemistry , vol.262 , Issue.29 , pp. 14042-14048
    • Fiol, C.J.1    Mahrenholz, A.M.2    Wang, Y.3    Roeske, R.W.4    Roach, P.J.5
  • 30
    • 0037172661 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta modulates notch signaling and stability
    • Foltz, D.R., Santiago, M.C., Berechid, B.E., Nye, J.S., Glycogen synthase kinase-3beta modulates notch signaling and stability. Current Biology: CB 12:12 (2002), 1006–1011.
    • (2002) Current Biology: CB , vol.12 , Issue.12 , pp. 1006-1011
    • Foltz, D.R.1    Santiago, M.C.2    Berechid, B.E.3    Nye, J.S.4
  • 31
    • 0037018924 scopus 로고    scopus 로고
    • Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation
    • Greene, M.W., Garofalo, R.S., Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation. Biochemistry 41:22 (2002), 7082–7091.
    • (2002) Biochemistry , vol.41 , Issue.22 , pp. 7082-7091
    • Greene, M.W.1    Garofalo, R.S.2
  • 32
    • 38149054804 scopus 로고    scopus 로고
    • Axin and GSK3-control Smad3 protein stability and modulate TGF-signaling
    • Guo, X., Ramirez, A., Waddell, D.S., Li, Z., Liu, X., Wang, X.F., Axin and GSK3-control Smad3 protein stability and modulate TGF-signaling. Genes & Development 22:1 (2008), 106–120.
    • (2008) Genes & Development , vol.22 , Issue.1 , pp. 106-120
    • Guo, X.1    Ramirez, A.2    Waddell, D.S.3    Li, Z.4    Liu, X.5    Wang, X.F.6
  • 33
    • 67649206084 scopus 로고    scopus 로고
    • Lithium trial in Alzheimer's disease: A randomized, single-blind, placebo-controlled, multicenter 10-week study
    • Hampel, H., Ewers, M., Burger, K., Annas, P., Mortberg, A., Bogstedt, A., et al. Lithium trial in Alzheimer's disease: A randomized, single-blind, placebo-controlled, multicenter 10-week study. The Journal of Clinical Psychiatry 70:6 (2009), 922–931.
    • (2009) The Journal of Clinical Psychiatry , vol.70 , Issue.6 , pp. 922-931
    • Hampel, H.1    Ewers, M.2    Burger, K.3    Annas, P.4    Mortberg, A.5    Bogstedt, A.6
  • 34
    • 84862888714 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3-beta phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization
    • Han, X., Ju, J.H., Shin, I., Glycogen synthase kinase 3-beta phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization. Biochemical and Biophysical Research Communications 423:2 (2012), 282–288.
    • (2012) Biochemical and Biophysical Research Communications , vol.423 , Issue.2 , pp. 282-288
    • Han, X.1    Ju, J.H.2    Shin, I.3
  • 35
    • 61849088424 scopus 로고    scopus 로고
    • Tau phosphorylation: The therapeutic challenge for neurodegenerative disease
    • Hanger, D.P., Anderton, B.H., Noble, W., Tau phosphorylation: The therapeutic challenge for neurodegenerative disease. Trends in Molecular Medicine 15:3 (2009), 112–119.
    • (2009) Trends in Molecular Medicine , vol.15 , Issue.3 , pp. 112-119
    • Hanger, D.P.1    Anderton, B.H.2    Noble, W.3
  • 36
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • Hardy, J.A., Higgins, G.A., Alzheimer's disease: The amyloid cascade hypothesis. Science 256:5054 (1992), 184–185.
    • (1992) Science , vol.256 , Issue.5054 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 38
    • 0028870305 scopus 로고
    • Glycogen synthase kinase 3 regulates cell fate in Dictyostelium
    • Harwood, A.J., Plyte, S.E., Woodgett, J., Strutt, H., Kay, R.R., Glycogen synthase kinase 3 regulates cell fate in Dictyostelium. Cell 80:1 (1995), 139–148.
    • (1995) Cell , vol.80 , Issue.1 , pp. 139-148
    • Harwood, A.J.1    Plyte, S.E.2    Woodgett, J.3    Strutt, H.4    Kay, R.R.5
  • 39
    • 0028931511 scopus 로고
    • Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
    • He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E., Dawid, I.B., Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 374:6523 (1995), 617–622.
    • (1995) Nature , vol.374 , Issue.6523 , pp. 617-622
    • He, X.1    Saint-Jeannet, J.P.2    Woodgett, J.R.3    Varmus, H.E.4    Dawid, I.B.5
  • 41
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich, K.P., Luo, J., Rubie, E.A., Tsao, M.S., Jin, O., Woodgett, J.R., Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406:6791 (2000), 86–90.
    • (2000) Nature , vol.406 , Issue.6791 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 42
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil, G.S., Peraldi, P., Budavari, A., Ellis, R., White, M.F., Spiegelman, B.M., IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:5249 (1996), 665–668.
    • (1996) Science , vol.271 , Issue.5249 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 43
    • 0027475421 scopus 로고
    • Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation
    • Hughes, K., Nikolakaki, E., Plyte, S.E., Totty, N.F., Woodgett, J.R., Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation. The EMBO Journal 12:2 (1993), 803–808.
    • (1993) The EMBO Journal , vol.12 , Issue.2 , pp. 803-808
    • Hughes, K.1    Nikolakaki, E.2    Plyte, S.E.3    Totty, N.F.4    Woodgett, J.R.5
  • 44
    • 62849118806 scopus 로고    scopus 로고
    • Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta
    • Jin, Y.H., Kim, H., Oh, M., Ki, H., Kim, K., Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta. Molecules and Cells 27:1 (2009), 15–19.
    • (2009) Molecules and Cells , vol.27 , Issue.1 , pp. 15-19
    • Jin, Y.H.1    Kim, H.2    Oh, M.3    Ki, H.4    Kim, K.5
  • 46
    • 55849135237 scopus 로고    scopus 로고
    • Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation
    • Kerkela, R., Kockeritz, L., Macaulay, K., Zhou, J., Doble, B.W., Beahm, C., et al. Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. The Journal of Clinical Investigation 118:11 (2008), 3609–3618.
    • (2008) The Journal of Clinical Investigation , vol.118 , Issue.11 , pp. 3609-3618
    • Kerkela, R.1    Kockeritz, L.2    Macaulay, K.3    Zhou, J.4    Doble, B.W.5    Beahm, C.6
  • 47
    • 80051806451 scopus 로고    scopus 로고
    • GSK-3 is a master regulator of neural progenitor homeostasis
    • Kim, W.Y., Wang, X., Wu, Y., Doble, B.W., Patel, S., Woodgett, J.R., et al. GSK-3 is a master regulator of neural progenitor homeostasis. Nature Neuroscience 12:11 (2009), 1390–1397.
    • (2009) Nature Neuroscience , vol.12 , Issue.11 , pp. 1390-1397
    • Kim, W.Y.1    Wang, X.2    Wu, Y.3    Doble, B.W.4    Patel, S.5    Woodgett, J.R.6
  • 48
    • 17044423920 scopus 로고    scopus 로고
    • Lithium-mediated phosphorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha
    • Kirshenboim, N., Plotkin, B., Shlomo, S.B., Kaidanovich-Beilin, O., Eldar-Finkelman, H., Lithium-mediated phosphorylation of glycogen synthase kinase-3beta involves PI3 kinase-dependent activation of protein kinase C-alpha. Journal of Molecular Neuroscience 24:2 (2004), 237–245.
    • (2004) Journal of Molecular Neuroscience , vol.24 , Issue.2 , pp. 237-245
    • Kirshenboim, N.1    Plotkin, B.2    Shlomo, S.B.3    Kaidanovich-Beilin, O.4    Eldar-Finkelman, H.5
  • 50
    • 0014378428 scopus 로고
    • Hormonal and non-hormonal control of glycogen synthesis-control of transferase phosphatase and transferase I kinase
    • Larner, J., Villar-Palasi, C., Goldberg, N.D., Bishop, J.S., Huijing, F., Wenger, J.I., et al. Hormonal and non-hormonal control of glycogen synthesis-control of transferase phosphatase and transferase I kinase. Advances in Enzyme Regulation 6 (1968), 409–423.
    • (1968) Advances in Enzyme Regulation , vol.6 , pp. 409-423
    • Larner, J.1    Villar-Palasi, C.2    Goldberg, N.D.3    Bishop, J.S.4    Huijing, F.5    Wenger, J.I.6
  • 52
    • 0032955426 scopus 로고    scopus 로고
    • Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
    • Lesort, M., Jope, R.S., Johnson, G.V., Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. Journal of Neurochemistry 72:2 (1999), 576–584.
    • (1999) Journal of Neurochemistry , vol.72 , Issue.2 , pp. 576-584
    • Lesort, M.1    Jope, R.S.2    Johnson, G.V.3
  • 53
    • 33644849088 scopus 로고    scopus 로고
    • Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta
    • Li, T., Hawkes, C., Qureshi, H.Y., Kar, S., Paudel, H.K., Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3beta. Biochemistry 45:10 (2006), 3134–3145.
    • (2006) Biochemistry , vol.45 , Issue.10 , pp. 3134-3145
    • Li, T.1    Hawkes, C.2    Qureshi, H.Y.3    Kar, S.4    Paudel, H.K.5
  • 54
    • 14244255271 scopus 로고    scopus 로고
    • Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling
    • Liberman, Z., Eldar-Finkelman, H., Serine 332 phosphorylation of insulin receptor substrate-1 by glycogen synthase kinase-3 attenuates insulin signaling. The Journal of Biological Chemistry 280:6 (2005), 4422–4428.
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.6 , pp. 4422-4428
    • Liberman, Z.1    Eldar-Finkelman, H.2
  • 57
    • 34247865533 scopus 로고    scopus 로고
    • A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation
    • Lochhead, P.A., Kinstrie, R., Sibbet, G., Rawjee, T., Morrice, N., Cleghon, V., A chaperone-dependent GSK3beta transitional intermediate mediates activation-loop autophosphorylation. Molecular Cell 24:4 (2006), 627–633.
    • (2006) Molecular Cell , vol.24 , Issue.4 , pp. 627-633
    • Lochhead, P.A.1    Kinstrie, R.2    Sibbet, G.3    Rawjee, T.4    Morrice, N.5    Cleghon, V.6
  • 59
    • 34548841091 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism
    • MacAulay, K., Doble, B.W., Patel, S., Hansotia, T., Sinclair, E.M., Drucker, D.J., et al. Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metabolism 6:4 (2007), 329–337.
    • (2007) Cell Metabolism , vol.6 , Issue.4 , pp. 329-337
    • MacAulay, K.1    Doble, B.W.2    Patel, S.3    Hansotia, T.4    Sinclair, E.M.5    Drucker, D.J.6
  • 62
    • 0036469290 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
    • Morfini, G., Szebenyi, G., Elluru, R., Ratner, N., Brady, S.T., Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility. The EMBO Journal 21:3 (2002), 281–293.
    • (2002) The EMBO Journal , vol.21 , Issue.3 , pp. 281-293
    • Morfini, G.1    Szebenyi, G.2    Elluru, R.3    Ratner, N.4    Brady, S.T.5
  • 63
    • 0035983533 scopus 로고    scopus 로고
    • Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta
    • Mukai, F., Ishiguro, K., Sano, Y., Fujita, S.C., Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta. Journal of Neurochemistry 81:5 (2002), 1073–1083.
    • (2002) Journal of Neurochemistry , vol.81 , Issue.5 , pp. 1073-1083
    • Mukai, F.1    Ishiguro, K.2    Sano, Y.3    Fujita, S.C.4
  • 64
    • 0036302960 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle
    • Nikoulina, S.E., Ciaraldi, T.P., Mudaliar, S., Carter, L., Johnson, K., Henry, R.R., Inhibition of glycogen synthase kinase 3 improves insulin action and glucose metabolism in human skeletal muscle. Diabetes 51:7 (2002), 2190–2198.
    • (2002) Diabetes , vol.51 , Issue.7 , pp. 2190-2198
    • Nikoulina, S.E.1    Ciaraldi, T.P.2    Mudaliar, S.3    Carter, L.4    Johnson, K.5    Henry, R.R.6
  • 65
    • 0020585165 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo
    • Parker, P.J., Caudwell, F.B., Cohen, P., Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo. European Journal of Biochemistry 130:1 (1983), 227–234.
    • (1983) European Journal of Biochemistry , vol.130 , Issue.1 , pp. 227-234
    • Parker, P.J.1    Caudwell, F.B.2    Cohen, P.3
  • 67
    • 79251544548 scopus 로고    scopus 로고
    • Tissue-specific analysis of glycogen synthase kinase-3alpha (GSK-3alpha) in glucose metabolism: Effect of strain variation
    • Patel, S., Macaulay, K., Woodgett, J.R., Tissue-specific analysis of glycogen synthase kinase-3alpha (GSK-3alpha) in glucose metabolism: Effect of strain variation. PLoS One, 6(1), 2011, e15845.
    • (2011) PLoS One , vol.6 , Issue.1 , pp. e15845
    • Patel, S.1    Macaulay, K.2    Woodgett, J.R.3
  • 68
    • 4544317872 scopus 로고    scopus 로고
    • Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter
    • Pearce, N.J., Arch, J.R., Clapham, J.C., Coghlan, M.P., Corcoran, S.L., Lister, C.A., et al. Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter. Metabolism 53:10 (2004), 1322–1330.
    • (2004) Metabolism , vol.53 , Issue.10 , pp. 1322-1330
    • Pearce, N.J.1    Arch, J.R.2    Clapham, J.C.3    Coghlan, M.P.4    Corcoran, S.L.5    Lister, C.A.6
  • 72
    • 0037155737 scopus 로고    scopus 로고
    • Proteolysis of the hedgehog signaling effector cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1
    • Price, M.A., Calderon, D., Proteolysis of the hedgehog signaling effector cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1. Cell 108:6 (2002), 823–835.
    • (2002) Cell , vol.108 , Issue.6 , pp. 823-835
    • Price, M.A.1    Calderon, D.2
  • 73
    • 0037339766 scopus 로고    scopus 로고
    • Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo
    • Ring, D.B., Johnson, K.W., Henriksen, E.J., Nuss, J.M., Goff, D., Kinnick, T.R., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52:3 (2003), 588–595.
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 588-595
    • Ring, D.B.1    Johnson, K.W.2    Henriksen, E.J.3    Nuss, J.M.4    Goff, D.5    Kinnick, T.R.6
  • 74
    • 27544442991 scopus 로고    scopus 로고
    • Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain
    • Ryan, K.A., Pimplikar, S.W., Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain. The Journal of Cell Biology 171:2 (2005), 327–335.
    • (2005) The Journal of Cell Biology , vol.171 , Issue.2 , pp. 327-335
    • Ryan, K.A.1    Pimplikar, S.W.2
  • 75
    • 0025322840 scopus 로고
    • Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3
    • Siegfried, E., Perkins, L.A., Capaci, T.M., Perrimon, N., Putative protein kinase product of the Drosophila segment-polarity gene zeste-white3. Nature 345:6278 (1990), 825–829.
    • (1990) Nature , vol.345 , Issue.6278 , pp. 825-829
    • Siegfried, E.1    Perkins, L.A.2    Capaci, T.M.3    Perrimon, N.4
  • 76
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • Stambolic, V., Ruel, L., Woodgett, J.R., Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Current Biology: CB 6:12 (1996), 1664–1668.
    • (1996) Current Biology: CB , vol.6 , Issue.12 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 77
    • 2642552331 scopus 로고    scopus 로고
    • Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
    • Su, Y., Ryder, J., Li, B., Wu, X., Fox, N., Solenberg, P., et al. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry 43:22 (2004), 6899–6908.
    • (2004) Biochemistry , vol.43 , Issue.22 , pp. 6899-6908
    • Su, Y.1    Ryder, J.2    Li, B.3    Wu, X.4    Fox, N.5    Solenberg, P.6
  • 80
    • 33646869503 scopus 로고    scopus 로고
    • Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP
    • Tempe, D., Casas, M., Karas, S., Blanchet-Tournier, M.F., Concordet, J.P., Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP. Molecular and Cellular Biology 26:11 (2006), 4316–4326.
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.11 , pp. 4316-4326
    • Tempe, D.1    Casas, M.2    Karas, S.3    Blanchet-Tournier, M.F.4    Concordet, J.P.5
  • 82
    • 78650656329 scopus 로고    scopus 로고
    • Does GSK-3 provide a shortcut for PI3K activation of Wnt signaling?
    • Voskas, D., Ling, L.S., Woodgett, J.R., Does GSK-3 provide a shortcut for PI3K activation of Wnt signaling?. F1000 Biology Reports, 2, 2010, 82.
    • (2010) F1000 Biology Reports , vol.2 , pp. 82
    • Voskas, D.1    Ling, L.S.2    Woodgett, J.R.3
  • 83
    • 0022347547 scopus 로고
    • Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells
    • White, M.F., Maron, R., Kahn, C.R., Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells. Nature 318:6042 (1985), 183–186.
    • (1985) Nature , vol.318 , Issue.6042 , pp. 183-186
    • White, M.F.1    Maron, R.2    Kahn, C.R.3
  • 84
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • Woodgett, J.R., Molecular cloning and expression of glycogen synthase kinase-3/factor A. The EMBO Journal 9:8 (1990), 2431–2438.
    • (1990) The EMBO Journal , vol.9 , Issue.8 , pp. 2431-2438
    • Woodgett, J.R.1
  • 85
    • 0036281126 scopus 로고    scopus 로고
    • Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain
    • Yao, H.B., Shaw, P.C., Wong, C.C., Wan, D.C., Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain. Journal of Chemical Neuroanatomy 23:4 (2002), 291–297.
    • (2002) Journal of Chemical Neuroanatomy , vol.23 , Issue.4 , pp. 291-297
    • Yao, H.B.1    Shaw, P.C.2    Wong, C.C.3    Wan, D.C.4
  • 86
    • 0042357237 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
    • Zhang, F., Phiel, C.J., Spece, L., Gurvich, N., Klein, P.S., Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. The Journal of Biological Chemistry 278 (2003), 33067–33077.
    • (2003) The Journal of Biological Chemistry , vol.278 , pp. 33067-33077
    • Zhang, F.1    Phiel, C.J.2    Spece, L.3    Gurvich, N.4    Klein, P.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.