메뉴 건너뛰기




Volumn 22, Issue 3, 2003, Pages 494-501

Structural basis for recruitment of glycogen synthase kinase 3β to the axin-APC scaffold complex

Author keywords

catenin; Insulin signalling; Phosphorylation; Signal transduction; Wnt signalling

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; FRAT PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH FACTOR; INSULIN; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 0037415737     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg068     Document Type: Article
Times cited : (279)

References (30)
  • 1
    • 0035665719 scopus 로고    scopus 로고
    • The structure of phosphorylated GSK-3β complexed with a peptide FRATtide, that inhibits β-catenin phosphorylation
    • Bax,B. et al. (2001) The structure of phosphorylated GSK-3β complexed with a peptide, FRATtide, that inhibits β-catenin phosphorylation. Structure, 9, 1143-1152.
    • (2001) Structure , vol.9 , pp. 1143-1152
    • Bax, B.1
  • 3
    • 0029918062 scopus 로고    scopus 로고
    • Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1
    • Bourne,Y., Watson,M.H., Hickey,M.J., Holmes,W., Rocque,W., Reed,S.I. and Tainer,J.A. (1996) Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1. Cell, 84, 863-874.
    • (1996) Cell , vol.84 , pp. 863-874
    • Bourne, Y.1    Watson, M.H.2    Hickey, M.J.3    Holmes, W.4    Rocque, W.5    Reed, S.I.6    Tainer, J.A.7
  • 4
    • 3543012707 scopus 로고    scopus 로고
    • Crystallography and NMR system: A new software suite for macromolecular structure determination
    • Brünger,A.T. et al. (1998) Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D, 54, 905-921.
    • (1998) Acta Crystallogr. D , vol.54 , pp. 905-921
    • Brünger, A.T.1
  • 5
    • 0030866897 scopus 로고    scopus 로고
    • Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
    • Canagarajah,B.J., Khokhlatchev,A., Cobb,M.H. and Goldsmith,E.J. (1997) Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell, 90, 859-869.
    • (1997) Cell , vol.90 , pp. 859-869
    • Canagarajah, B.J.1    Khokhlatchev, A.2    Cobb, M.H.3    Goldsmith, E.J.4
  • 6
    • 0028103275 scopus 로고
    • The CCP4 suite: Programs for protein crystallography
    • CCP4(1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D, 50, 760-763.
    • (1994) Acta Crystallogr. D , vol.50 , pp. 760-763
  • 7
    • 0035875098 scopus 로고    scopus 로고
    • Crystal structure of glycogen synthase kinase 3β: Structural basis for phosphate-primed substrate specificity and autoinhibition
    • Dajani,R., Fraser,E., Roe,S.M., Young,N., Good,V., Dale,T.C. and Pearl,L.H. (2001) Crystal structure of glycogen synthase kinase 3β: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell, 105, 721-732.
    • (2001) Cell , vol.105 , pp. 721-732
    • Dajani, R.1    Fraser, E.2    Roe, S.M.3    Young, N.4    Good, V.5    Dale, T.C.6    Pearl, L.H.7
  • 8
    • 0036629249 scopus 로고    scopus 로고
    • Wnt signal transduction: Kinase cogs in a nano-machine?
    • Ding,Y.N. and Dale,T. (2002) Wnt signal transduction: kinase cogs in a nano-machine? Trends Biochem. Sci., 27, 327-329.
    • (2002) Trends Biochem. Sci. , vol.27 , pp. 327-329
    • Ding, Y.N.1    Dale, T.2
  • 9
    • 0037013313 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β mutagenesis identifies a common binding domain for GBP and axin
    • Ferkey,D.M. and Kimelman,D. (2002) Glycogen synthase kinase-3β mutagenesis identifies a common binding domain for GBP and axin. J. Biol. Chem., 277, 16147-16152.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16147-16152
    • Ferkey, D.M.1    Kimelman, D.2
  • 10
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
    • Frame,S., Cohen,P. and Biondi,R.M. (2001) A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol. Cell, 7, 1321-1327.
    • (2001) Mol. Cell , vol.7 , pp. 1321-1327
    • Frame, S.1    Cohen, P.2    Biondi, R.M.3
  • 11
    • 0037127255 scopus 로고    scopus 로고
    • Identification of the axin and Frat binding region of glycogen synthase kinase-3
    • Fraser,E. et al. (2002) Identification of the axin and Frat binding region of glycogen synthase kinase-3. J. Biol. Chem., 277, 2176-2185.
    • (2002) J. Biol. Chem. , vol.277 , pp. 2176-2185
    • Fraser, E.1
  • 12
    • 0032492954 scopus 로고    scopus 로고
    • Downregulation of β-catenin by human axin and its association with the APC tumor suppressor, β-catenin and GSK3β
    • Hart,M.J., de los Santos,R., Albert,I.N., Rubinfeld,B. and Polakis,P. (1998) Downregulation of β-catenin by human axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr. Biol., 8, 573-581.
    • (1998) Curr. Biol. , vol.8 , pp. 573-581
    • Hart, M.J.1    De los Santos, R.2    Albert, I.N.3    Rubinfeld, B.4    Polakis, P.5
  • 13
    • 0035967897 scopus 로고    scopus 로고
    • Regulation of GSK-3: A cellular multiprocessor
    • Harwood,A.J. (2001) Regulation of GSK-3: a cellular multiprocessor. Cell, 105, 821-824.
    • (2001) Cell , vol.105 , pp. 821-824
    • Harwood, A.J.1
  • 15
    • 0033524929 scopus 로고    scopus 로고
    • Identification of a domain of axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain
    • Hsu,W., Zeng,L. and Costantini,F. (1999) Identification of a domain of axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain. J. Biol. Chem., 274, 3439-3445.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3439-3445
    • Hsu, W.1    Zeng, L.2    Costantini, F.3
  • 16
    • 0032473355 scopus 로고    scopus 로고
    • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin
    • Ikeda,S., Kishida,S., Yamamoto,H., Murai,H., Koyama,S. and Kikuchi,A. (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin. EMBO J., 17, 1371-1384.
    • (1998) EMBO J. , vol.17 , pp. 1371-1384
    • Ikeda, S.1    Kishida, S.2    Yamamoto, H.3    Murai, H.4    Koyama, S.5    Kikuchi, A.6
  • 17
    • 0029590306 scopus 로고
    • Specific modulation of ectodermal cell cell fates in Xenopus embryos by glocogen synthase kinase
    • Itoh,K., Tang,T.L., Neel,B.G. and Sokol,S.Y. (1995) Specific modulation of ectodermal cell cell fates in Xenopus embryos by glocogen synthase kinase. Development, 121, 3979-3988.
    • (1995) Development , vol.121 , pp. 3979-3988
    • Itoh, K.1    Tang, T.L.2    Neel, B.G.3    Sokol, S.Y.4
  • 18
    • 0004148514 scopus 로고
    • MRC Laboratory of Molecular Biology, Cambridge, UK
    • Leslie,A.G.W. (1995) MOSFLM Users Guide. MRC Laboratory of Molecular Biology, Cambridge, UK.
    • (1995) MOSFLM Users Guide
    • Leslie, A.G.W.1
  • 20
    • 0037155691 scopus 로고    scopus 로고
    • Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu,C., Li,Y., Semenov,M., Han,C., Baeg,G.-H., Tan,Y., Zhang,Z., Lin,X. and He,X. (2002) Control of β-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell, 108, 837-847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.-H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 21
    • 0030603104 scopus 로고    scopus 로고
    • Tyrosine dephosphorylation of glycogen synthase kinase-3 is involved in its extracellular signal-dependent inactivation
    • Murai,H., Okazaki,M. and Kikuchi,A. (1996) Tyrosine dephosphorylation of glycogen synthase kinase-3 is involved in its extracellular signal-dependent inactivation. FEBS Lett., 392, 153-160.
    • (1996) FEBS Lett. , vol.392 , pp. 153-160
    • Murai, H.1    Okazaki, M.2    Kikuchi, A.3
  • 22
    • 84920325457 scopus 로고
    • AMoRE - An automated package for molecular replacement
    • Navaza,J. (1994) AMoRE-an automated package for molecular replacement. Acta Crystallogr. D, 50, 157-163.
    • (1994) Acta Crystallogr. D , vol.50 , pp. 157-163
    • Navaza, J.1
  • 23
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis,P. (2000) Wnt signaling and cancer. Genes Dev., 14, 1837-1851.
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 24
    • 0033605639 scopus 로고    scopus 로고
    • Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A
    • Seeling,J.M., Miller,J.R., Gil,R., Moon,R.T., White,R. and Virshup,D.M. (1999) Regulation of β-catenin signaling by the B56 subunit of protein phosphatase 2A. Science, 283, 2089-2091.
    • (1999) Science , vol.283 , pp. 2089-2091
    • Seeling, J.M.1    Miller, J.R.2    Gil, R.3    Moon, R.T.4    White, R.5    Virshup, D.M.6
  • 25
    • 0033577732 scopus 로고    scopus 로고
    • Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription
    • Smalley,M.J. et al. (1999) Interaction of axin and Dvl-2 proteins regulates Dvl-2- stimulated TCF-dependent transcription. EMBO J., 18, 2823-2835.
    • (1999) EMBO J. , vol.18 , pp. 2823-2835
    • Smalley, M.J.1
  • 26
    • 0035265679 scopus 로고    scopus 로고
    • Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2
    • Song,H.W., Hanlon,N., Brown,N.R., Noble, M.E,M., Johnson,L.N. and Barford,D. (2001) Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2. Mol. Cell, 7, 615-626.
    • (2001) Mol. Cell , vol.7 , pp. 615-626
    • Song, H.W.1    Hanlon, N.2    Brown, N.R.3    Noble, M.E.M.4    Johnson, L.N.5    Barford, D.6
  • 27
    • 0032821768 scopus 로고    scopus 로고
    • A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and β-catenin
    • Thomas,G.M., Frame,S., Goedert,M., Nathke, I., Polakis,P. and Cohen,P. (1999) A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and β-catenin. FEBS Lett., 458, 247-251.
    • (1999) FEBS Lett. , vol.458 , pp. 247-251
    • Thomas, G.M.1    Frame, S.2    Goedert, M.3    Nathke, I.4    Polakis, P.5    Cohen, P.6
  • 28
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signalling in development
    • Wodarz,A. and Nusse,R. (1998) Mechanisms of Wnt signalling in development. Annu. Rev. Cell. Dev. Biol., 14, 59-88.
    • (1998) Annu. Rev. Cell. Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 29
    • 0037007231 scopus 로고    scopus 로고
    • Casein kinase I phsophorylates the Armadillo protein and induces its degradation in Drosophila
    • Yanagawa,S., Matsuda,Y., Lee,J.-S., Matsubayashi,H., Sese,S., Kadowaki,T. and Ishimoto,A. (2002) Casein kinase I phsophorylates the Armadillo protein and induces its degradation in Drosophila. EMBO J., 21, 1733-1742.
    • (2002) EMBO J. , vol.21 , pp. 1733-1742
    • Yanagawa, S.1    Matsuda, Y.2    Lee, J.-S.3    Matsubayashi, H.4    Sese, S.5    Kadowaki, T.6    Ishimoto, A.7
  • 30
    • 0032511194 scopus 로고    scopus 로고
    • GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
    • Yost,C., Farr,G.H., Pierce,S.B., Ferkey,D.M., Chen,M.M. and Kimelman,D. (1998) GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis. Cell, 93, 1031-1041.
    • (1998) Cell , vol.93 , pp. 1031-1041
    • Yost, C.1    Farr, G.H.2    Pierce, S.B.3    Ferkey, D.M.4    Chen, M.M.5    Kimelman, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.