메뉴 건너뛰기




Volumn 23, Issue 7, 2008, Pages 704-711

A feasibility and tolerability study of lithium in Alzheimer's disease

Author keywords

Alzheimer's disease; Disease modifying; GSK 3; Lithium; Trial

Indexed keywords

LITHIUM;

EID: 48249096759     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.1964     Document Type: Article
Times cited : (144)

References (43)
  • 1
    • 33847123499 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: Lessons from lithium
    • Aghdam SY, Barger SW. 2007. Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium. Curr Alzheimer Res 4(1): 21-31.
    • (2007) Curr Alzheimer Res , vol.4 , Issue.1 , pp. 21-31
    • Aghdam, S.Y.1    Barger, S.W.2
  • 2
    • 34250160589 scopus 로고    scopus 로고
    • Greater cortical gray matter density in lithium-treated patients with bipolar disorder
    • Bearden CE, Thompson PM, Dalwani M, et al. 2007a. Greater cortical gray matter density in lithium-treated patients with bipolar disorder. Biol Psychiatry 62(1): 7-16.
    • (2007) Biol Psychiatry , vol.62 , Issue.1 , pp. 7-16
    • Bearden, C.E.1    Thompson, P.M.2    Dalwani, M.3
  • 3
    • 34548397689 scopus 로고    scopus 로고
    • Three-dimensional mapping of hippocampal anatomy in unmedicated and lithium-treated patients with bipolar disorder
    • Aug 8; [Epub ahead of print
    • Bearden CE, Thompson PM, Dutton RA, et al. 2007b. Three-dimensional mapping of hippocampal anatomy in unmedicated and lithium-treated patients with bipolar disorder. Neuropsychopharmacol, 2007 Aug 8; [Epub ahead of print]
    • (2007) Neuropsychopharmacol
    • Bearden, C.E.1    Thompson, P.M.2    Dutton, R.A.3
  • 4
    • 3042558276 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A drug target for CNS therapies
    • Bhat RV, Budd Haeberlein SL, Avila J. 2004b. Glycogen synthase kinase 3: a drug target for CNS therapies. J Neurochem 89(6): 1313-1317.
    • (2004) J Neurochem , vol.89 , Issue.6 , pp. 1313-1317
    • Bhat, R.V.1    Budd Haeberlein, S.L.2    Avila, J.3
  • 5
    • 3042558276 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A drug target for CNS therapies
    • Bhat RV, Budd Haeberlein SL, Avila J. 2004a. Glycogen synthase kinase 3: a drug target for CNS therapies. J Neurochem 89(6): 1313-1317.
    • (2004) J Neurochem , vol.89 , Issue.6 , pp. 1313-1317
    • Bhat, R.V.1    Budd Haeberlein, S.L.2    Avila, J.3
  • 6
    • 34250222104 scopus 로고    scopus 로고
    • In search of the Holy Grail for the treatment of neurodegenerative disorders: Has a simple cation been overlooked?
    • Chuang DM, Manji HK. 2007. In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked? Biol Psychiatry 62(1): 4-6.
    • (2007) Biol Psychiatry , vol.62 , Issue.1 , pp. 4-6
    • Chuang, D.M.1    Manji, H.K.2
  • 7
    • 0027985334 scopus 로고
    • The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia
    • Cummings JL, Mega M, Gray K, et al. 1994. The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. Neurology 44(12): 2308-2314.
    • (1994) Neurology , vol.44 , Issue.12 , pp. 2308-2314
    • Cummings, J.L.1    Mega, M.2    Gray, K.3
  • 8
    • 0037220599 scopus 로고    scopus 로고
    • Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
    • De Ferrari GV, Chacon MA, Barria MI, et al. 2003. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol Psychiatry 8(2): 195-208.
    • (2003) Mol Psychiatry , vol.8 , Issue.2 , pp. 195-208
    • De Ferrari, G.V.1    Chacon, M.A.2    Barria, M.I.3
  • 9
    • 16844363453 scopus 로고    scopus 로고
    • Does lithium therapy protect against the onset of DEMENTIA?
    • Dunn N, Holmes C, Mullee M. 2005. Does lithium therapy protect against the onset of DEMENTIA? Alzheimer Dis Assoc Disord 19(1): 20-22.
    • (2005) Alzheimer Dis Assoc Disord , vol.19 , Issue.1 , pp. 20-22
    • Dunn, N.1    Holmes, C.2    Mullee, M.3
  • 10
    • 33847701675 scopus 로고    scopus 로고
    • The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration
    • Ellul J, Archer N, Foy CM, et al. 2007. The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration. J Neurol Neurosurg Psychiatry 78(3): 233-239.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , Issue.3 , pp. 233-239
    • Ellul, J.1    Archer, N.2    Foy, C.M.3
  • 11
    • 29144508843 scopus 로고    scopus 로고
    • Global prevalence of dementia: A Delphi consensus study
    • Ferri CP, Prince M, Brayne C, et al. 2005. Global prevalence of dementia: a Delphi consensus study. Lancet 366(9503): 2112-2117.
    • (2005) Lancet , vol.366 , Issue.9503 , pp. 2112-2117
    • Ferri, C.P.1    Prince, M.2    Brayne, C.3
  • 12
    • 0016823810 scopus 로고
    • Mini-Mental State'. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. 1975. 'Mini-Mental State'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 13
    • 37249032577 scopus 로고    scopus 로고
    • A systematic review of existing data on long-term lithium therapy: Neuroprotective or neurotoxic?
    • Epub ahead of print
    • Fountoulakis KN, Vieta E, Bouras C, et al. 2007. A systematic review of existing data on long-term lithium therapy: neuroprotective or neurotoxic? Int J Neuropsychopharmacol 1-19. [Epub ahead of print]
    • (2007) Int J Neuropsychopharmacol , pp. 1-19
    • Fountoulakis, K.N.1    Vieta, E.2    Bouras, C.3
  • 14
    • 0242475154 scopus 로고    scopus 로고
    • Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau
    • Ghribi O, Prammonjago P, Herman MM, et al. 2003. Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain Res Mol Brain Res 119(2): 201-206.
    • (2003) Brain Res Mol Brain Res , vol.119 , Issue.2 , pp. 201-206
    • Ghribi, O.1    Prammonjago, P.2    Herman, M.M.3
  • 15
    • 48249087049 scopus 로고    scopus 로고
    • The Lithium Side Effects Rating Scale (LISERS); development of a self-rating instrument
    • s5
    • Haddad P, Wieck A, Yarrow M, Denham P. 1999. The Lithium Side Effects Rating Scale (LISERS); development of a self-rating instrument. Eur Neuropsychopharmacol 9(s5): 231-232.
    • (1999) Eur Neuropsychopharmacol , vol.9 , pp. 231-232
    • Haddad, P.1    Wieck, A.2    Yarrow, M.3    Denham, P.4
  • 16
    • 1642363745 scopus 로고    scopus 로고
    • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments
    • Hernandez F, Borrell J, Guaza C, et al. 2002. Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J Neurochem 83(6): 1529-1533.
    • (2002) J Neurochem , vol.83 , Issue.6 , pp. 1529-1533
    • Hernandez, F.1    Borrell, J.2    Guaza, C.3
  • 17
    • 0031842242 scopus 로고    scopus 로고
    • The Bayer Activities of Daily Living Scale (B-ABL)
    • Hindmarch I, Lehfeld H, De Jongh P, Erzigkeit H. 1998. The Bayer Activities of Daily Living Scale (B-ABL). Dementia 9 (Suppl. 2): 20-26.
    • (1998) Dementia , vol.9 , Issue.SUPPL. 2 , pp. 20-26
    • Hindmarch, I.1    Lehfeld, H.2    De Jongh, P.3    Erzigkeit, H.4
  • 18
    • 33846259727 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibition is integral to long-term potentiation
    • Hooper C, Markevich V, Plattner F, et al. 2007. Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. Eur J Neurosci 25(1): 81-86.
    • (2007) Eur J Neurosci , vol.25 , Issue.1 , pp. 81-86
    • Hooper, C.1    Markevich, V.2    Plattner, F.3
  • 19
    • 33750894549 scopus 로고    scopus 로고
    • Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease
    • Huang He, Klein PS. 2006. Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease. Curr Drug Targets 7(11): 1389-1397.
    • (2006) Curr Drug Targets , vol.7 , Issue.11 , pp. 1389-1397
    • He, H.1    Klein, P.S.2
  • 20
    • 8844273441 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease
    • Hye A, Kerr F, Archer N, et al. 2005. Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neurosci Lett 373(1): 1-4.
    • (2005) Neurosci Lett , vol.373 , Issue.1 , pp. 1-4
    • Hye, A.1    Kerr, F.2    Archer, N.3
  • 21
    • 33750596715 scopus 로고    scopus 로고
    • Proteome-based plasma biomarkers for Alzheimer's disease
    • Hye A, Lynham S, Thambisetty M, et al. 2006. Proteome-based plasma biomarkers for Alzheimer's disease. Brain 129 (Pt 11): 3042-3050.
    • (2006) Brain , vol.129 , Issue.PART 11 , pp. 3042-3050
    • Hye, A.1    Lynham, S.2    Thambisetty, M.3
  • 22
    • 0037118247 scopus 로고    scopus 로고
    • Human wild-type tau interacts with wingless pathway components and produces neurofibrillary tangles in Drosophila
    • Jackson GR, Wiedau-Pazos M, Sang T-K, et al. 2002. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary tangles in Drosophila. Neuron 34: 509-519.
    • (2002) Neuron , vol.34 , pp. 509-519
    • Jackson, G.R.1    Wiedau-Pazos, M.2    Sang, T.-K.3
  • 23
    • 0042379932 scopus 로고    scopus 로고
    • Lithium and GSK-3: One inhibitor, two inhibitory actions, multiple outcomes
    • Jope RS. 2003. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol Sci 24(9): 441-443.
    • (2003) Trends Pharmacol Sci , vol.24 , Issue.9 , pp. 441-443
    • Jope, R.S.1
  • 24
    • 0033989639 scopus 로고    scopus 로고
    • The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase- 3β activity
    • Leroy K, Menu R, Conreur JL, et al. 2000. The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase- 3β activity. FEBS Lett 465: 34-38.
    • (2000) FEBS Lett , vol.465 , pp. 34-38
    • Leroy, K.1    Menu, R.2    Conreur, J.L.3
  • 25
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas JJ, Hernandez F, Gomez-Ramos P, et al. 2001. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 20(1-2): 27-39.
    • (2001) EMBO J , vol.20 , Issue.1-2 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3
  • 26
    • 34447503455 scopus 로고    scopus 로고
    • Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
    • Mazanetz MP, Fischer PM. 2007. Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases. Nat Rev Drug Discov 6(6): 464-479.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.6 , pp. 464-479
    • Mazanetz, M.P.1    Fischer, P.M.2
  • 27
    • 0034619037 scopus 로고    scopus 로고
    • Lithium-induced increase in human brain grey matter
    • Moore GJ, Bebchuk JM, Wilds IB, et al. 2000. Lithium-induced increase in human brain grey matter. Lancet 356(9237): 1241-1242.
    • (2000) Lancet , vol.356 , Issue.9237 , pp. 1241-1242
    • Moore, G.J.1    Bebchuk, J.M.2    Wilds, I.B.3
  • 28
    • 0036150827 scopus 로고    scopus 로고
    • Alzheimer's disease - do tauists and baptists finally shake hands?
    • Mudher A, Lovestone S. 2002. Alzheimer's disease - do tauists and baptists finally shake hands? Trends Neurosci 25(1): 22-26.
    • (2002) Trends Neurosci , vol.25 , Issue.1 , pp. 22-26
    • Mudher, A.1    Lovestone, S.2
  • 29
    • 3142592230 scopus 로고    scopus 로고
    • GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
    • Mudher A, Shepherd D, Newman TA, et al. 2004. GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Mol Psychiatry 9(5): 522-530.
    • (2004) Mol Psychiatry , vol.9 , Issue.5 , pp. 522-530
    • Mudher, A.1    Shepherd, D.2    Newman, T.A.3
  • 30
    • 0034857290 scopus 로고    scopus 로고
    • Lithium-induced nephrogenic diabetes insipidus in older people
    • Mukhopadhyay D, Gokulkrishnan L, Mohanaruban K. 2001. Lithium-induced nephrogenic diabetes insipidus in older people. Age Ageing 30(4): 347-350.
    • (2001) Age Ageing , vol.30 , Issue.4 , pp. 347-350
    • Mukhopadhyay, D.1    Gokulkrishnan, L.2    Mohanaruban, K.3
  • 31
    • 21044449225 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
    • Noble W, Planel E, Zehr C, et al. 2005. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc Natl Acad Sci USA 102(19): 6990-6995.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.19 , pp. 6990-6995
    • Noble, W.1    Planel, E.2    Zehr, C.3
  • 32
    • 34147210411 scopus 로고    scopus 로고
    • Lithium and risk for Alzheimer's disease in elderly patients with bipolar disorder
    • Nunes PV, Forlenza OV, Gattaz WF. 2007. Lithium and risk for Alzheimer's disease in elderly patients with bipolar disorder. Br J Psychiatry 190: 359-360.
    • (2007) Br J Psychiatry , vol.190 , pp. 359-360
    • Nunes, P.V.1    Forlenza, O.V.2    Gattaz, W.F.3
  • 33
    • 0034083519 scopus 로고    scopus 로고
    • Lithium: Thyroid effects and altered renal handling
    • Oakley PW, Dawson AH, Whyte IM. 2000. Lithium: thyroid effects and altered renal handling. J Toxicol Clin Toxicol 38(3): 333-337.
    • (2000) J Toxicol Clin Toxicol , vol.38 , Issue.3 , pp. 333-337
    • Oakley, P.W.1    Dawson, A.H.2    Whyte, I.M.3
  • 34
    • 34247195008 scopus 로고    scopus 로고
    • Lithium-induced sinus node disease at therapeutic concentrations: Linking lithium-induced blockade of sodium channels to impaired pacemaker activity
    • Oudit GY, Korley V, Backx PH, Dorian P. 2007. Lithium-induced sinus node disease at therapeutic concentrations: linking lithium-induced blockade of sodium channels to impaired pacemaker activity. Can J Cardiol 23(3): 229-232.
    • (2007) Can J Cardiol , vol.23 , Issue.3 , pp. 229-232
    • Oudit, G.Y.1    Korley, V.2    Backx, P.H.3    Dorian, P.4
  • 35
    • 0032850599 scopus 로고    scopus 로고
    • Distribution of active glycogen synthase kinase 3β (GSK- 3β) in brains staged for Alzheimer disease neurofibrillary changes
    • Pei JJ, Braak E, Braak H, et al. 1999. Distribution of active glycogen synthase kinase 3β (GSK- 3β) in brains staged for Alzheimer disease neurofibrillary changes. J Neuropathol Exp Neurol 58: 1010-1019.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1010-1019
    • Pei, J.J.1    Braak, E.2    Braak, H.3
  • 36
    • 0019967975 scopus 로고
    • The Global Deterioration Scale for assessment of primary degenerative dementia
    • Reisberg B, Ferris SH, De Leon MJ, Crook T. 1982. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 139: 1136-1139.
    • (1982) Am J Psychiatry , vol.139 , pp. 1136-1139
    • Reisberg, B.1    Ferris, S.H.2    De Leon, M.J.3    Crook, T.4
  • 37
    • 33847214486 scopus 로고    scopus 로고
    • Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation
    • Rockenstein E, Torrance M, Adame A, et al. 2007. Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation. J Neurosci 27(8): 1981-1991.
    • (2007) J Neurosci , vol.27 , Issue.8 , pp. 1981-1991
    • Rockenstein, E.1    Torrance, M.2    Adame, A.3
  • 38
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. 1984. A new rating scale for Alzheimer's disease. Am J Psychiatry 141(11): 1356-1364.
    • (1984) Am J Psychiatry , vol.141 , Issue.11 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 39
    • 17844403242 scopus 로고    scopus 로고
    • Incidence of delirium in older adults newly prescribed lithium or valproate: A population-based cohort study
    • Shulman KI, Sykora K, Gill S, et al. 2005. Incidence of delirium in older adults newly prescribed lithium or valproate: a population-based cohort study. J Clin Psychiatry 66(4): 424-427.
    • (2005) J Clin Psychiatry , vol.66 , Issue.4 , pp. 424-427
    • Shulman, K.I.1    Sykora, K.2    Gill, S.3
  • 41
    • 30344465046 scopus 로고    scopus 로고
    • A retrospective analysis of risk and protective factors for natural death in bipolar disorder
    • Tsai SY, Lee CH, Kuo CJ, Chen CC. 2005. A retrospective analysis of risk and protective factors for natural death in bipolar disorder. J Clin Psychiatry 66(12): 1586-1591.
    • (2005) J Clin Psychiatry , vol.66 , Issue.12 , pp. 1586-1591
    • Tsai, S.Y.1    Lee, C.H.2    Kuo, C.J.3    Chen, C.C.4
  • 42
    • 33845346815 scopus 로고    scopus 로고
    • Disease-modifying trials in Alzheimer's disease: A European task force consensus
    • Vellas B, Andrieu S, Sampaio C, Wilcock G. 2007. Disease-modifying trials in Alzheimer's disease: a European task force consensus. Lancet Neurol 6(1): 56-62.
    • (2007) Lancet Neurol , vol.6 , Issue.1 , pp. 56-62
    • Vellas, B.1    Andrieu, S.2    Sampaio, C.3    Wilcock, G.4
  • 43
    • 0030881425 scopus 로고    scopus 로고
    • Lithium therapy, hypercalcemia, and hyperparathyroidism
    • Wolf ME, Moffat M, Mosnaim J, Dempsey S. 1997. Lithium therapy, hypercalcemia, and hyperparathyroidism. Am J Ther 4(9-10): 323-325.
    • (1997) Am J Ther , vol.4 , Issue.9-10 , pp. 323-325
    • Wolf, M.E.1    Moffat, M.2    Mosnaim, J.3    Dempsey, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.