Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets

Cell

Volumn 168, Issue 1-2, 2017, Pages 159-171.e14

  Shin, Yongdae ^a   Berry, Joel ^a   Pannucci, Nicole ^b   Haataja, Mikko P ^a   Toettcher, Jared E ^b   Brangwynne, Clifford P ^a  

^a Princeton University   (United States)

^b PRINCETON UNIVERSITY   (United States)

Author keywords

aggregation; fluisomes; gelation; intracellular condensates; intrinsically disordered protein; liquid liquid phase separation; membraneless organelles; optogenetics; ribonucleoprotein bodies; RNA binding protein

Indexed keywords

CRYPTOCHROME 2; INTRINSICALLY DISORDERED PROTEIN; RIBONUCLEOPROTEIN; ARABIDOPSIS PROTEIN; CRY2 PROTEIN, ARABIDOPSIS; CRYPTOCHROME; PROTEIN;

ABSORPTION LAG TIME; ANIMAL CELL; ARTICLE; BLUE LIGHT; CELL ACTIVATION; CELL AGING; CELL KINETICS; CONTROLLED STUDY; DIFFUSION COEFFICIENT; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMAN; IMAGE ANALYSIS; IN VITRO STUDY; INACTIVATION RATE CONSTANT; INTRACELLULAR SIGNALING; LIGHT; MOLECULAR INTERACTION; NONHUMAN; OPTOGENETICS; PHASE SEPARATION; PHASE TRANSITION; PRIORITY JOURNAL; SPATIOTEMPORAL ANALYSIS; STEADY STATE; ANIMAL; CHEMICAL MODEL; CHEMISTRY; KINETICS; METABOLISM; MOLECULAR IMAGING; MOUSE; NIH 3T3 CELL LINE; PROCEDURES; PROTEIN PROTEIN INTERACTION;

ANIMALS; ARABIDOPSIS PROTEINS; CRYPTOCHROMES; INTRINSICALLY DISORDERED PROTEINS; KINETICS; LIGHT; MICE; MODELS, CHEMICAL; MOLECULAR IMAGING; NIH 3T3 CELLS; OPTOGENETICS; PHASE TRANSITION; PROTEIN INTERACTION MAPS; PROTEINS;

EID: 85009211737     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.11.054     Document Type: Article

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