Spatial organization of the cell cytoplasm by position-dependent phase separation

Physical Review Letters

Volumn 111, Issue 8, 2013, Pages

  Lee, Chiu Fan ^a   Brangwynne, Clifford P ^a,b   Gharakhani, Jöbin ^a   Hyman, Anthony A ^b   Jülicher, Frank ^a  

^a MAX PLANCK INSTITUT FÜR PHYSIK KOMPLEXER SYSTEME   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC-CELLS; CELL CYTOPLASM; ELEGANS; LIQUID-LIQUID PHASE SEPARATION; PHASE SEPARATION MECHANISM; PROTEIN CONCENTRATIONS; SPATIAL ORGANIZATION;

CELL PROLIFERATION; CELLS; CYTOLOGY;

PHASE SEPARATION;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CHEMISTRY; CYTOPLASM; METABOLISM; PHYSIOLOGY;

ANIMALS; CAENORHABDITIS ELEGANS; CYTOPLASM; MODELS, BIOLOGICAL;

EID: 84883207900     PISSN: 00319007     EISSN: 10797114     Source Type: Journal    
DOI: 10.1103/PhysRevLett.111.088101     Document Type: Article

References (20)

1. B. Alberts, Molecular Biology of the Cell (Garland Science, New York, 2002), 4th ed.
2. K. E. Kasza, A. C. Rowat, J. Liu, T. E Angelini, C. P. Brangwynne, G. H Koenderink, and D. A Weitz, Curr. Opin. Cell Biol. 19, 101 (2007). COCBE3 0955-0674 10.1016/j.ceb.2006.12.002
3. P. Gonczy, Nat. Rev. Mol. Cell Biol. 9, 355 (2008). NRMCBP 1471-0072 10.1038/nrm2388
4. D. Updike and S. Strome, Journal of andrology 31, 53 (2010). JOAND3 0196-3635 10.2164/jandrol.109.008292
5. C. P. Brangwynne, C. R. Eckmann, D. S. Courson, A. Rybarska, C. Hoege, J. Gharakhani, F. Jülicher, and A. A. Hyman, Science 324, 1729 (2009). SCIEAS 0036-8075 10.1126/science.1172046
6. R. Cheeks, J. C. Canman, W. N Gabriel, N. Meyer, S. Strome, and B. Goldstein, Curr. Biol. 14, 851 (2004). CUBLE2 0960-9822 10.1016/j.cub.2004.05. 022
7. B. Goldstein and I. Macara, Dev. Cell 13, 609 (2007). 1534-5807 10.1016/j.devcel.2007.10.007
8. S. Schneider and B. Bowerman, Annu. Rev. Genet. 37, 221 (2003). ARVGB7 0066-4197 10.1146/annurev.genet.37.110801.142443
9. C. Spike and S. Strome, Curr. Biol. 13, R837 (2003). CUBLE2 0960-9822 10.1016/j.cub.2003.10.016
10. C. DeRenzo, K. Reese, and G. Seydoux, Nature (London) 424, 685 (2003). NATUAS 0028-0836 10.1038/nature01887
11. J. A. Schisa, J. N. Pitt, and J. R. Priess, Development (Cambridge, U.K.) 128, 1287 (2001). DEVPED 0950-1991
12. A. A. Cuenca, A. Schetter, D. Aceto, K. Kemphues, and G. Seydoux, Development (Cambridge, U.K.) 130, 1255 (2003). DEVPED 0950-1991 10.1242/dev.00284
13. J.-P. Hansen and I. R. McDonald, Theory of Simple Liquids (Academic Press, London, 2006), 3rd ed.
14. C. M. Gallo, J. T. Wang, F. Motegi, and G. Seydoux, Science 330, 1685 (2010). SCIEAS 0036-8075 10.1126/science.1193697
15. J. Tenlen, J. N. Molk, N. London, B. D. Page, and J. R. Priess, Development (Cambridge, U.K.) 135, 3665 (2008). DEVPED 0950-1991 10.1242/dev.027060
16. B. Daniels, T. M. Dobrowsky, E. M. Perkins, S. X. Sun, and D. Wirtz, Development (Cambridge, U.K.) 137, 2579 (2010). DEVPED 0950-1991 10.1242/dev.051326
17. E. E. Griffin, D. J. Odde, and G. Seydoux, Cell 146, 955 (2011). CELLB5 0092-8674 10.1016/j.cell.2011.08.012
18. C. P. Brangwynne, T. J. Mitchison, and A. A. Hyman, Proc. Natl. Acad. Sci. U.S.A. 108, 4334 (2011). PNASA6 0027-8424 10.1073/pnas.1017150108
19. S. Weber and C. P. Brangwynne, Cell 149, 1188 (2012). CELLB5 0092-8674 10.1016/j.cell.2012.05.022
20. C. P. Brangwynne, Soft Matter 7, 3052 (2011). SMOABF 1744-683X 10.1039/c0sm00981d