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Volumn 65, Issue 1, 2017, Pages 20-30

Protective effects of bezafibrate against elaidic acid-induced accumulation of lipid droplets in monocytic cells

Author keywords

Bezafibrate; Elaidic acid; Lipid droplets; Oleic acid; Palmitic acid

Indexed keywords

BEZAFIBRATE; CD36 ANTIGEN; ELAIDIC ACID; FAT DROPLET; MONOCYTE CHEMOTACTIC PROTEIN 1; OLEIC ACID; PALMITIC ACID; SUPEROXIDE; TUMOR NECROSIS FACTOR;

EID: 85008640148     PISSN: None     EISSN: 24523186     Source Type: Journal    
DOI: 10.1016/j.retram.2016.08.001     Document Type: Article
Times cited : (4)

References (68)
  • 1
    • 14744297613 scopus 로고    scopus 로고
    • Metabolic and health effects of isomeric fatty acids
    • Mensink, R.P., Metabolic and health effects of isomeric fatty acids. Curr Opin Lipidol 16 (2005), 27–30.
    • (2005) Curr Opin Lipidol , vol.16 , pp. 27-30
    • Mensink, R.P.1
  • 2
    • 73949160338 scopus 로고    scopus 로고
    • Ruminant and industrially produced trans fatty acids: health aspects
    • Stender, S., Astrup, A., Dyerberg, J., Ruminant and industrially produced trans fatty acids: health aspects. Food Nutr Res, 2008, 52.
    • (2008) Food Nutr Res , pp. 52
    • Stender, S.1    Astrup, A.2    Dyerberg, J.3
  • 3
    • 65649136224 scopus 로고    scopus 로고
    • Health effects of trans-fatty acids: experimental and observational evidence
    • Mozaffarian, D., Aro, A., Willett, W.C., Health effects of trans-fatty acids: experimental and observational evidence. Eur J Clin Nutr 63 (2009), 5–21.
    • (2009) Eur J Clin Nutr , vol.63 , pp. 5-21
    • Mozaffarian, D.1    Aro, A.2    Willett, W.C.3
  • 4
    • 33744796514 scopus 로고    scopus 로고
    • Trans fatty acids – effects on systemic inflammation and endothelial function
    • Mozaffarian, D., Trans fatty acids – effects on systemic inflammation and endothelial function. Atheroscler Suppl 7 (2006), 29–32.
    • (2006) Atheroscler Suppl , vol.7 , pp. 29-32
    • Mozaffarian, D.1
  • 5
    • 0031009308 scopus 로고    scopus 로고
    • Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    • Pietinen, P., Ascherio, A., Korhonen, P., Hartman, A.M., Willett, W.C., Albanes, D., et al. Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am J Epidemiol 145 (1997), 876–887.
    • (1997) Am J Epidemiol , vol.145 , pp. 876-887
    • Pietinen, P.1    Ascherio, A.2    Korhonen, P.3    Hartman, A.M.4    Willett, W.C.5    Albanes, D.6
  • 6
    • 0035836025 scopus 로고    scopus 로고
    • Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study
    • Oomen, C.M., Ocké, M.C., Feskens, E.J., van Erp-Baart, M.A., Kok, F.J., Kromhout, D., Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study. Lancet 357 (2001), 746–751.
    • (2001) Lancet , vol.357 , pp. 746-751
    • Oomen, C.M.1    Ocké, M.C.2    Feskens, E.J.3    van Erp-Baart, M.A.4    Kok, F.J.5    Kromhout, D.6
  • 8
    • 40549122292 scopus 로고    scopus 로고
    • Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study
    • Chardigny, J.M., Destaillats, F., Malpuech-Brugère, C., Moulin, J., Bauman, D.E., Lock, A.L., et al. Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study. Am J ClinNutr 87 (2008), 558–566.
    • (2008) Am J ClinNutr , vol.87 , pp. 558-566
    • Chardigny, J.M.1    Destaillats, F.2    Malpuech-Brugère, C.3    Moulin, J.4    Bauman, D.E.5    Lock, A.L.6
  • 9
    • 38949186392 scopus 로고    scopus 로고
    • Intake of ruminant trans fatty acids and risk of coronary heart disease
    • Jakobsen, M.U., Overvad, K., Dyerberg, J., Heitmann, B.L., Intake of ruminant trans fatty acids and risk of coronary heart disease. Int J Epidemiol 37 (2008), 173–182.
    • (2008) Int J Epidemiol , vol.37 , pp. 173-182
    • Jakobsen, M.U.1    Overvad, K.2    Dyerberg, J.3    Heitmann, B.L.4
  • 11
    • 0031019222 scopus 로고    scopus 로고
    • Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production
    • Liu, Y., Hultén, L.M., Wiklund, O., Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production. ArteriosclerThrombVasc Biol 17 (1997), 317–323.
    • (1997) ArteriosclerThrombVasc Biol , vol.17 , pp. 317-323
    • Liu, Y.1    Hultén, L.M.2    Wiklund, O.3
  • 12
    • 4444264910 scopus 로고    scopus 로고
    • Serial studies of mouse atherosclerosis by in vivo magnetic resonance imaging detect lesion regression after correction of dyslipidemia
    • Trogan, E., Fayad, Z.A., Itskovich, V.V., Aguinaldo, J.G., Mani, V., Fallon, J.T., et al. Serial studies of mouse atherosclerosis by in vivo magnetic resonance imaging detect lesion regression after correction of dyslipidemia. ArteriosclerThrombVasc Biol 24 (2004), 1714–1719.
    • (2004) ArteriosclerThrombVasc Biol , vol.24 , pp. 1714-1719
    • Trogan, E.1    Fayad, Z.A.2    Itskovich, V.V.3    Aguinaldo, J.G.4    Mani, V.5    Fallon, J.T.6
  • 13
    • 0034994989 scopus 로고    scopus 로고
    • Peroxisome proliferator-activatedreceptors in atherosclerosis and inflammation – an update
    • Elangbam, C.S., Tyler, R.D., Lightfoot, R.M., Peroxisome proliferator-activatedreceptors in atherosclerosis and inflammation – an update. Toxicol Pathol 29 (2001), 224–231.
    • (2001) Toxicol Pathol , vol.29 , pp. 224-231
    • Elangbam, C.S.1    Tyler, R.D.2    Lightfoot, R.M.3
  • 14
    • 0032565868 scopus 로고    scopus 로고
    • Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators
    • Staels, B., Koenig, W., Habib, A., Merval, R., Lebret, M., Torra, I.P., et al. Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature 393 (1998), 790–793.
    • (1998) Nature , vol.393 , pp. 790-793
    • Staels, B.1    Koenig, W.2    Habib, A.3    Merval, R.4    Lebret, M.5    Torra, I.P.6
  • 15
    • 0035895313 scopus 로고    scopus 로고
    • PPARalpha agonists inhibit tissue factor expression in human monocytes and macrophages
    • Neve, B.P., Corseaux, D., Chinetti, G., Zawadzki, C., Fruchart, J.C., Duriez, P., et al. PPARalpha agonists inhibit tissue factor expression in human monocytes and macrophages. Circulation 103 (2001), 207–212.
    • (2001) Circulation , vol.103 , pp. 207-212
    • Neve, B.P.1    Corseaux, D.2    Chinetti, G.3    Zawadzki, C.4    Fruchart, J.C.5    Duriez, P.6
  • 16
    • 51849097150 scopus 로고    scopus 로고
    • Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264.7macrophage-derived foam cells
    • Ringseis, R., Wen, G., Saal, D., Eder, K., Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264.7macrophage-derived foam cells. Lipids 43 (2008), 913–923.
    • (2008) Lipids , vol.43 , pp. 913-923
    • Ringseis, R.1    Wen, G.2    Saal, D.3    Eder, K.4
  • 17
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz, P., Nagy, L., Alvarez, J.G., Thomazy, V.A., Evans, R.M., PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93 (1998), 241–252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 18
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger, J., Moller, D.E., The mechanisms of action of PPARs. Annu Rev Med 53 (2002), 409–435.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 19
    • 0029960080 scopus 로고    scopus 로고
    • Induction of apoptosis in endothelial cells treated with cholesterol oxides
    • Lizard, G., Deckert, V., Dubrez, L., Moisant, M., Gambert, P., Lagrost, L., Induction of apoptosis in endothelial cells treated with cholesterol oxides. Am J Pathol 148 (1996), 1625–1638.
    • (1996) Am J Pathol , vol.148 , pp. 1625-1638
    • Lizard, G.1    Deckert, V.2    Dubrez, L.3    Moisant, M.4    Gambert, P.5    Lagrost, L.6
  • 20
    • 24344434230 scopus 로고    scopus 로고
    • Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols
    • Lemaire-Ewing, S., Prunet, C., Montange, T., Vejux, A., Berthier, A., Bessède, G., et al. Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols. Cell Biol Toxicol 21 (2005), 97–114.
    • (2005) Cell Biol Toxicol , vol.21 , pp. 97-114
    • Lemaire-Ewing, S.1    Prunet, C.2    Montange, T.3    Vejux, A.4    Berthier, A.5    Bessède, G.6
  • 21
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin
    • Rothe, G., Valet, G., Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J Leukoc Biol 47 (1990), 440–448.
    • (1990) J Leukoc Biol , vol.47 , pp. 440-448
    • Rothe, G.1    Valet, G.2
  • 22
    • 0031570036 scopus 로고    scopus 로고
    • Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis
    • Macho, A., Hirsch, T., Marzo, I., Marchetti, P., Dallaporta, B., Susin, S.A., et al. Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. J Immunol 158 (1997), 4612–4619.
    • (1997) J Immunol , vol.158 , pp. 4612-4619
    • Macho, A.1    Hirsch, T.2    Marzo, I.3    Marchetti, P.4    Dallaporta, B.5    Susin, S.A.6
  • 23
    • 33745788418 scopus 로고    scopus 로고
    • Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients
    • Prunet, C., Montange, T., Véjux, A., Laubriet, A., Rohmer, J.F., Riedinger, J.M., et al. Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients. Cytometry A 69 (2006), 359–373.
    • (2006) Cytometry A , vol.69 , pp. 359-373
    • Prunet, C.1    Montange, T.2    Véjux, A.3    Laubriet, A.4    Rohmer, J.F.5    Riedinger, J.M.6
  • 24
    • 0030910850 scopus 로고    scopus 로고
    • A novel technique for mapping the lipid composition of atherosclerotic fatty streaks by en face fluorescence microscopy
    • Klinkner, A.M., Bugelski, P.J., Waites, C.R., Louden, C., Hart, T.K., Kerns, W.D., A novel technique for mapping the lipid composition of atherosclerotic fatty streaks by en face fluorescence microscopy. J Histochem Cytochem 45 (1997), 743–753.
    • (1997) J Histochem Cytochem , vol.45 , pp. 743-753
    • Klinkner, A.M.1    Bugelski, P.J.2    Waites, C.R.3    Louden, C.4    Hart, T.K.5    Kerns, W.D.6
  • 25
    • 20144388767 scopus 로고    scopus 로고
    • 7 Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry. FRET biphoton spectral imaging microscopy, and subcellular fractionation
    • Vejux, A., Kahn, E., Dumas, D., Bessède, G., Ménétrier, F., Athias, A., et al. 7 Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry. FRET biphoton spectral imaging microscopy, and subcellular fractionation. Cytometry A 64 (2005), 87–100.
    • (2005) Cytometry A , vol.64 , pp. 87-100
    • Vejux, A.1    Kahn, E.2    Dumas, D.3    Bessède, G.4    Ménétrier, F.5    Athias, A.6
  • 26
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch, J., Lees, M., Sloane Stanley, G.H., A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957), 497–509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 27
    • 0038135048 scopus 로고    scopus 로고
    • Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
    • Mensink, R.P., Zock, P.L., Kester, A.D., Katan, M.B., Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 77 (2003), 1146–1155.
    • (2003) Am J Clin Nutr , vol.77 , pp. 1146-1155
    • Mensink, R.P.1    Zock, P.L.2    Kester, A.D.3    Katan, M.B.4
  • 28
    • 80055019374 scopus 로고    scopus 로고
    • Fatty acids and inflammation: the cutting edge between food and pharma
    • Calder, P.C., Fatty acids and inflammation: the cutting edge between food and pharma. Eur J Pharmacol 668 (2011), 50–58.
    • (2011) Eur J Pharmacol , vol.668 , pp. 50-58
    • Calder, P.C.1
  • 29
    • 79955657300 scopus 로고    scopus 로고
    • Trans fatty acids, insulin resistance and diabetes
    • Thompson, A.K., Minihane, A.M., Williams, C.M., Trans fatty acids, insulin resistance and diabetes. Eur J Clin Nutr 65 (2011), 553–564.
    • (2011) Eur J Clin Nutr , vol.65 , pp. 553-564
    • Thompson, A.K.1    Minihane, A.M.2    Williams, C.M.3
  • 30
    • 34547959340 scopus 로고    scopus 로고
    • Trans fat diet induces abdominal obesity and changes in insulin sensitivity in monkeys
    • Kavanagh, K., Jones, K.L., Sawyer, J., Kelley, K., Carr, J.J., Wagner, J.D., et al. Trans fat diet induces abdominal obesity and changes in insulin sensitivity in monkeys. Obesity (Silver Spring) 15 (2007), 1675–1684.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 1675-1684
    • Kavanagh, K.1    Jones, K.L.2    Sawyer, J.3    Kelley, K.4    Carr, J.J.5    Wagner, J.D.6
  • 31
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi, H., Kokoeva, M.V., Inouye, K., Tzameli, I., Yin, H., Flier, J.S., TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116 (2006), 3015–3025.
    • (2006) J Clin Invest , vol.116 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 32
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha
    • Suganami, T., Nishida, J., Ogawa, Y., A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. ArteriosclerThrombVasc Biol 25 (2005), 2062–2068.
    • (2005) ArteriosclerThrombVasc Biol , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 33
    • 0346458940 scopus 로고    scopus 로고
    • Trans-unsaturated fatty acids and acrylamide in food as potential atherosclerosis progression factors. Based on own studies
    • Naruszewicz, M., Daniewski, M., Nowicka, G., Kozłowska-Wojciechowska, M., Trans-unsaturated fatty acids and acrylamide in food as potential atherosclerosis progression factors. Based on own studies. Acta Microbiol Pol 52 (2003), 75–81.
    • (2003) Acta Microbiol Pol , vol.52 , pp. 75-81
    • Naruszewicz, M.1    Daniewski, M.2    Nowicka, G.3    Kozłowska-Wojciechowska, M.4
  • 34
    • 77950888339 scopus 로고    scopus 로고
    • Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation
    • Schwartz, E.A., Zhang, W.Y., Karnik, S.K., Borwege, S., Anand, V.R., Laine, P.S., et al. Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. Arterioscler ThrombVasc Biol 30 (2010), 802–808.
    • (2010) Arterioscler ThrombVasc Biol , vol.30 , pp. 802-808
    • Schwartz, E.A.1    Zhang, W.Y.2    Karnik, S.K.3    Borwege, S.4    Anand, V.R.5    Laine, P.S.6
  • 35
    • 58549105701 scopus 로고    scopus 로고
    • Induction of pro-inflammatory cytokines by long-chain saturated fatty acids in human macrophages
    • Håversen, L., Danielsson, K.N., Fogelstrand, L., Wiklund, O., Induction of pro-inflammatory cytokines by long-chain saturated fatty acids in human macrophages. Atherosclerosis 202 (2009), 382–393.
    • (2009) Atherosclerosis , vol.202 , pp. 382-393
    • Håversen, L.1    Danielsson, K.N.2    Fogelstrand, L.3    Wiklund, O.4
  • 36
    • 80053554640 scopus 로고    scopus 로고
    • Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation
    • Holzer, R.G., Park, E.J., Li, N., Tran, H., Chen, M., Choi, C., et al. Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell 147 (2011), 173–184.
    • (2011) Cell , vol.147 , pp. 173-184
    • Holzer, R.G.1    Park, E.J.2    Li, N.3    Tran, H.4    Chen, M.5    Choi, C.6
  • 37
    • 0029153784 scopus 로고
    • Pathogenesis of oleic acid-induced lung injury in the rat: distribution of oleic acid during injury and early endothelial cell changes
    • Beilman, G., Pathogenesis of oleic acid-induced lung injury in the rat: distribution of oleic acid during injury and early endothelial cell changes. Lipids 30 (1995), 817–823.
    • (1995) Lipids , vol.30 , pp. 817-823
    • Beilman, G.1
  • 40
    • 80555149806 scopus 로고    scopus 로고
    • Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel activation
    • Ang, S.F., Sio, S.W., Moochhala, S.M., MacAry, P.A., Bhatia, M., Hydrogen sulfide upregulates cyclooxygenase-2 and prostaglandin E metabolite in sepsis-evoked acute lung injury via transient receptor potential vanilloid type 1 channel activation. J Immunol 187 (2011), 4778–4787.
    • (2011) J Immunol , vol.187 , pp. 4778-4787
    • Ang, S.F.1    Sio, S.W.2    Moochhala, S.M.3    MacAry, P.A.4    Bhatia, M.5
  • 42
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer, G., Galluzzi, L., Brenner, C., Mitochondrial membrane permeabilization in cell death. Physiol Rev 87 (2007), 99–163.
    • (2007) Physiol Rev , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 43
    • 77953525682 scopus 로고    scopus 로고
    • Dietary fatty acids modulate antigen presentation to hepatic NKT cells in non-alcoholic fatty liver disease
    • Hua, J., Ma, X., Webb, T., Potter, J.J., Oelke, M., Li, Z., Dietary fatty acids modulate antigen presentation to hepatic NKT cells in non-alcoholic fatty liver disease. J Lipid Res 51 (2010), 1696–1703.
    • (2010) J Lipid Res , vol.51 , pp. 1696-1703
    • Hua, J.1    Ma, X.2    Webb, T.3    Potter, J.J.4    Oelke, M.5    Li, Z.6
  • 44
    • 0036896769 scopus 로고    scopus 로고
    • Fatty acid composition ofskeletal muscle reflects dietary fat composition in humans
    • Andersson, A., Nälsén, C., Tengblad, S., Vessby, B., Fatty acid composition ofskeletal muscle reflects dietary fat composition in humans. Am J Clin Nutr 76 (2009), 1222–1229.
    • (2009) Am J Clin Nutr , vol.76 , pp. 1222-1229
    • Andersson, A.1    Nälsén, C.2    Tengblad, S.3    Vessby, B.4
  • 45
    • 0035430782 scopus 로고    scopus 로고
    • Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation
    • Cnop, M., Hannaert, J.C., Hoorens, A., Eizirik, D.L., Pipeleers, D.G., Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation. Diabetes 50 (2001), 1771–1777.
    • (2001) Diabetes , vol.50 , pp. 1771-1777
    • Cnop, M.1    Hannaert, J.C.2    Hoorens, A.3    Eizirik, D.L.4    Pipeleers, D.G.5
  • 46
    • 65949090538 scopus 로고    scopus 로고
    • Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes
    • Ricchi, M., Odoardi, M.R., Carulli, L., Anzivino, C., Ballestri, S., Pinetti, A., et al. Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes. J Gastroenterol Hepatol 24 (2009), 830–840.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 830-840
    • Ricchi, M.1    Odoardi, M.R.2    Carulli, L.3    Anzivino, C.4    Ballestri, S.5    Pinetti, A.6
  • 48
    • 43949108922 scopus 로고    scopus 로고
    • The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity
    • Li, Z., Berk, M., McIntyre, T.M., Gores, G.J., Feldstein, A.E., The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity. Hepatology 47 (2008), 1495–1503.
    • (2008) Hepatology , vol.47 , pp. 1495-1503
    • Li, Z.1    Berk, M.2    McIntyre, T.M.3    Gores, G.J.4    Feldstein, A.E.5
  • 49
    • 0037423555 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha reduces cholesterol esterification in macrophages
    • Chinetti, G., Lestavel, S., Fruchart, J.C., Clavey, V., Staels, B., Peroxisome proliferator-activated receptor alpha reduces cholesterol esterification in macrophages. Circ Res 92 (2003), 212–217.
    • (2003) Circ Res , vol.92 , pp. 212-217
    • Chinetti, G.1    Lestavel, S.2    Fruchart, J.C.3    Clavey, V.4    Staels, B.5
  • 50
    • 0032502704 scopus 로고    scopus 로고
    • Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor
    • Mascaró, C., Acosta, E., Ortiz, J.A., Marrero, P.F., Hegardt, F.G., Haro, D., Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor. J Biol Chem 273 (1998), 8560–8563.
    • (1998) J Biol Chem , vol.273 , pp. 8560-8563
    • Mascaró, C.1    Acosta, E.2    Ortiz, J.A.3    Marrero, P.F.4    Hegardt, F.G.5    Haro, D.6
  • 51
    • 0034817390 scopus 로고    scopus 로고
    • Cloning of the human cholesteryl ester hydrolase promoter: identification of functional peroxisomal proliferator-activated receptor responsive elements
    • Ghosh, S., Natarajan, R., Cloning of the human cholesteryl ester hydrolase promoter: identification of functional peroxisomal proliferator-activated receptor responsive elements. Biochem Biophys Res Commun 284 (2001), 1065–1070.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 1065-1070
    • Ghosh, S.1    Natarajan, R.2
  • 52
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti, G., Lestavel, S., Bocher, V., Remaley, A.T., Neve, B., Torra, I.P., et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 7 (2001), 53–58.
    • (2001) Nat Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3    Remaley, A.T.4    Neve, B.5    Torra, I.P.6
  • 53
    • 0042165989 scopus 로고    scopus 로고
    • Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis
    • Feldstein, A.E., Canbay, A., Angulo, P., Taniai, M., Burgart, L.J., Lindor, K.D., et al. Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 125 (2003), 437–443.
    • (2003) Gastroenterology , vol.125 , pp. 437-443
    • Feldstein, A.E.1    Canbay, A.2    Angulo, P.3    Taniai, M.4    Burgart, L.J.5    Lindor, K.D.6
  • 55
    • 26144450287 scopus 로고    scopus 로고
    • Fatty acid structural requirements for the inhibition of endothelial activation
    • De Caterina, R., Bernini, W., Libby, P., Fatty acid structural requirements for the inhibition of endothelial activation. Circulation 94:Suppl. I (1996), I–I102.
    • (1996) Circulation , vol.94 , pp. I-I102
    • De Caterina, R.1    Bernini, W.2    Libby, P.3
  • 56
    • 0032478314 scopus 로고    scopus 로고
    • Fatty acid-induced beta cellapoptosis: a link between obesity and diabetes
    • Shimabukuro, M., Zhou, Y.T., Levi, M., Unger, R.H., Fatty acid-induced beta cellapoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A 95 (1998), 2498–2502.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2498-2502
    • Shimabukuro, M.1    Zhou, Y.T.2    Levi, M.3    Unger, R.H.4
  • 58
    • 0033035631 scopus 로고    scopus 로고
    • The double bond in unsaturated fatty acids is the necessary and sufficient requirement for the inhibition of expression of endothelial leukocyte adhesion molecules through interference with nuclear factor-kappaB activation
    • Massaro, M., Carluccio, M.A., Bonfrate, C., Siculella, L., Lazzerini, G., Bernini, W., et al. The double bond in unsaturated fatty acids is the necessary and sufficient requirement for the inhibition of expression of endothelial leukocyte adhesion molecules through interference with nuclear factor-kappaB activation. Lipids 34 Suppl. (1999), S213–S214.
    • (1999) Lipids , vol.34 Suppl. , pp. S213-S214
    • Massaro, M.1    Carluccio, M.A.2    Bonfrate, C.3    Siculella, L.4    Lazzerini, G.5    Bernini, W.6
  • 60
    • 0033105510 scopus 로고    scopus 로고
    • Molecular recognition of fatty acids by peroxisome proliferator-activated receptors
    • Xu, H.E., Lambert, M.H., Montana, V.G., Parks, D.J., Blanchard, S.G., Brown, P.J., et al. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell 3 (1999), 397–403.
    • (1999) Mol Cell , vol.3 , pp. 397-403
    • Xu, H.E.1    Lambert, M.H.2    Montana, V.G.3    Parks, D.J.4    Blanchard, S.G.5    Brown, P.J.6
  • 62
    • 10444278021 scopus 로고    scopus 로고
    • CD36, oxidized LDL and PPAR gamma: pathological interactions in macrophages and atherosclerosis
    • Nicholson, A.C., Hajjar, D.P., CD36, oxidized LDL and PPAR gamma: pathological interactions in macrophages and atherosclerosis. Vascul Pharmacol 41 (2004), 139–146.
    • (2004) Vascul Pharmacol , vol.41 , pp. 139-146
    • Nicholson, A.C.1    Hajjar, D.P.2
  • 63
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote, M., Li, A.C., Willson, T.M., Kelly, C.J., Glass, C.K., The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 391 (1998), 79–82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 64
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A.T., Seed, B., PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391 (1998), 82–86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 65
    • 0029982038 scopus 로고    scopus 로고
    • Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients
    • Ericsson, C.G., Hamsten, A., Nilsson, J., Grip, L., Svane, B., de Faire, U., Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients. Lancet 347 (1996), 849–853.
    • (1996) Lancet , vol.347 , pp. 849-853
    • Ericsson, C.G.1    Hamsten, A.2    Nilsson, J.3    Grip, L.4    Svane, B.5    de Faire, U.6
  • 66
    • 0024211259 scopus 로고
    • Inhibition of hepatic fatty acid oxidation by bezafibrate and bezafibroyl CoA
    • Eacho, P.I., Foxworthy, P.S., Inhibition of hepatic fatty acid oxidation by bezafibrate and bezafibroyl CoA. Biochem Biophys Res Commun 157 (1988), 1148–1153.
    • (1988) Biochem Biophys Res Commun , vol.157 , pp. 1148-1153
    • Eacho, P.I.1    Foxworthy, P.S.2
  • 67
    • 0842330592 scopus 로고    scopus 로고
    • Genetic defects in fatty acidbeta-oxidation and acyl-CoA dehydrogenases. Molecular pathogenesis andgenotype-phenotype relationships
    • Gregersen, N., Bross, P., Andresen, B.S., Genetic defects in fatty acidbeta-oxidation and acyl-CoA dehydrogenases. Molecular pathogenesis andgenotype-phenotype relationships. Eur J Biochem 271 (2004), 470–482.
    • (2004) Eur J Biochem , vol.271 , pp. 470-482
    • Gregersen, N.1    Bross, P.2    Andresen, B.S.3
  • 68
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann, I., Green, S., Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347 (1990), 645–650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2


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