Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264.7 macrophage-derived foam cells

Lipids

Volumn 43, Issue 10, 2008, Pages 913-923

  Ringseis, Robert ^a   Wen, Gaiping ^a   Saal, Daniela ^a   Eder, Klaus ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Atherosclerosis; Cholesterol accumulation; Cholesterol efflux; Conjugated linoleic acid; Macrophage foam cell; Peroxisome proliferator activated receptors

Indexed keywords

ABC TRANSPORTER A1; CD36 ANTIGEN; CHOLESTEROL; CHOLESTEROL ESTER; CONJUGATED LINOLEIC ACID; LINOLEIC ACID; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN; MESSENGER RNA;

ACETYLATION; ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL STRAIN; CONTROLLED STUDY; FOAM CELL; GENE EXPRESSION; HOMEOSTASIS; ISOMER; LIPID STORAGE; MACROPHAGE; MOUSE; NIEMANN PICK DISEASE; NONHUMAN;

ANIMALS; ANTIGENS, CD36; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CELL SURVIVAL; CHOLESTEROL; DNA-BINDING PROTEINS; FOAM CELLS; HUMANS; ISOMERISM; LINOLEIC ACIDS, CONJUGATED; MICE; PPAR GAMMA; PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; VESICULAR TRANSPORT PROTEINS;

EID: 51849097150     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-008-3226-x     Document Type: Article

References (57)

1. W Rosamond K Flegal G Friday K Furie A Go K Greenlund N Haase M Ho V Howard 2007 Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee Circulation 115 e69 e171
2. RG Gerrity HK Naito 1980 Ultrastructural identification of monocyte-derived foam cells in fatty streak lesions Artery 8 208 214
3. CK Glass JL Witztum 2001 Atherosclerosis: the road ahead Cell 104 503 516
4. G Chinetti S Lestavel V Bocher AT Remaley B Neve IP Torra E Teissier A Minnich M Jaye 2001 PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway Nat Med 7 53 58
5. G Chinetti S Lestavel JC Fruchart V Clavey B Staels 2003 Peroxisome proliferator-activated receptor α reduces cholesterol esterification in macrophages Circ Res 92 212 217
6. L Nagy P Tontonoz JG Alvarez H Chen RM Evans 1998 Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ Cell 93 229 240
7. P Tontonoz L Nagy JG Alvarez VA Thomazy RM Evans 1998 PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL Cell 93 241 252
8. A Chawla WA Boisvert CH Lee BA Laffitte Y Barak SB Joseph D Liao L Nagy PA Edwards 2001 PPARγ-LXR-ABCA1 Pathway in macrophages is involved in cholesterol efflux and atherogenesis Mol Cell 7 161 171
9. KJ Moore ED Rosen ML Fitzgerald F Randow LP Andersson D Altshuler DS Milstone RM Mortensen BM Spiegelman MW Freeman 2001 The role of PPAR-γ in macrophage differentiation and cholesterol uptake Nat Med 7 41 47
10. M Bodzioch E Orsó J Klucken T Langmann A Böttcher W Diederich W Drobnik S Barlage C Büchler 1999 The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease Nat Genet 22 347 351
11. A Brooks-Wilson M Marcil SM Clee LH Zhang K Roomp M van Dam L Yu C Brewer JA Collins 1999 Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency Nat Genet 22 336 345
12. S Rust M Rosier H Funke J Real Z Amoura JC Piette JF Deleuze HB Brewer N Duverger 1999 Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1 Nat Genet 22 352 355
13. G Chinetti-Gbaguidi E Rigamonti L Helin AL Mutka M Lepore JC Fruchart V Clavey E Ikonen S Lestavel B Staels 2005 Peroxisome proliferator-activated receptor α controls cellular cholesterol trafficking in macrophages J Lipid Res 46 2717 2725
14. ED Carstea JA Morris KG Coleman SK Loftus D Zhang C Cummings J Gu MA Rosenfeld WJ Pavan 1997 Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis Science 277 228 231
15. JF Strauss III P Liu LK Christenson H Watari 2002 Sterols and intracellular vesicular trafficking: lessons from the study of NPC1 Steroids 67 947 951
16. AC Li CJ Binder A Gutierrez KK Brown CR Plotkin JW Pattison AF Valledor RA Davis TM Willson 2004 Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ J Clin Invest 114 1564 1576
17. AR Collins WP Meehan U Kintscher S Jackson S Wakino G Noh W Palinski WA Hsueh RE Law 2001 Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice Arterioscler Thromb Vasc Biol 21 365 371
18. SY Moya-Camarena JP Vanden Heuvel SG Blanchard LA Leesnitzer MA Belury 1999 Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARα J Lipid Res 40 1426 1433
19. Y Yu PH Correll JP Vanden Heuvel 2002 Conjugated linoleic acid decreases production of pro-inflammatory products in macrophages: evidence for a PPARγ-dependent mechanism Biochim Biophys Acta 1581 89 99
20. R Ringseis A Müller C Herter S Gahler H Steinhart K Eder 2006 CLA isomers inhibit TNFα-induced eicosanoid release from human vascular smooth muscle cells via a PPARγ ligand-like action Biochim Biophys Acta 1760 290 300
21. S Toomey B Harhen HM Roche D Fitzgerald O Belton 2006 Profound resolution of early atherosclerosis with conjugated linoleic acid Atherosclerosis 187 40 49
22. D Kritchevsky SA Tepper S Wright P Tso SK Czarnecki 2000 Influence of conjugated linoleic acid (CLA) on establishment and progression of atherosclerosis in rabbits J Am Coll Nutr 19 472S 477S
23. PL Mitchell MA Langille DL Currie RS McLeod 2005 Effect of conjugated linoleic acid isomers on lipoproteins and atherosclerosis in the Syrian Golden hamster Biochim Biophys Acta 1734 269 276
24. S Tricon GC Burdge CM Williams PC Calder P Yaqoob 2005 The effects of conjugated linoleic acid on human health-related outcomes Proc Nutr Soc 64 171 182
25. S Tricon GC Burdge S Kew T Banerjee JJ Russell EL Jones RF Grimble CM Williams P Yaqoob PC Calder 2004 Opposing effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid on blood lipids in healthy humans Am J Clin Nutr 80 614 620
26. S Weldon S Mitchell D Kelleher MJ Gibney HM Roche 2004 Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages Atherosclerosis 174 261 273
27. G Agatha A Voigt E Kauf F Zintl 2004 Conjugated linoleic acid modulation of cell membrane in leukemia cells Cancer Lett 209 87 103
28. WL Cheng CK Lii HW Chen TH Lin KL Liu 2004 Contribution of conjugated linoleic acid to the suppression of inflammatory responses through the regulation of the NF-κB pathway J Agric Food Chem 52 71 78
29. R Ringseis A Müller K Düsterloh S Schleser K Eder H Steinhart 2006 Formation of conjugated linoleic acid metabolites in human vascular endothelial cells Biochim Biophys Acta 1761 377 383
30. A Cimini L Cristiano S Colafarina E Benedetti S Di Loreto C Festuccia F Amicarelli RA Canuto MP Cerù 2005 PPARγ-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF) Int J Cancer 117 923 933
31. K Kang W Liu KJ Albright Y Park MW Pariza 2003 Trans-10, cis-12 CLA inhibits differentiation of 3T3-L1 adipocytes and decreases PPARγ expression Biochem Biophys Res Commun 303 795 799
32. A Venkateswaran BA Laffitte SB Joseph PA Mak DC Wilpitz PA Edwards P Tontonoz 2000 Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα Proc Natl Acad Sci USA 97 12097 12102
33. D Calvo D Gómez-Coronado MA Lasunción MA Vega 1997 CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins Arterioscler Thromb Vasc Biol 17 2341 2349
34. D Calvo D Gómez-Coronado Y Suárez MA Lasunción MA Vega 1998 Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL J Lipid Res 39 777 788
35. G Endemann LW Stanton KS Madden CM Bryant RT White AA Protter 1993 CD36 is a receptor for oxidized low density lipoprotein J Biol Chem 268 11811 11816
36. VV Kunjathoor M Febbraio EA Podrez KJ Moore L Andersson S Koehn JS Rhee R Silverstein HF Hoff MW Freeman 2002 Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages J Biol Chem 277 49982 49988
37. N Araki S Horiuchi AT Rahim K Takata Y Morino 1990 Microquantification of cholesterol and cholesteryl esters in rat peritoneal macrophages by reverse-phase high-performance liquid chromatography Anal Biochem 185 339 345
38. J Han DP Hajjar M Febbraio AC Nicholson 1997 Native and modified low density lipoproteins increase the functional expression of the macrophage class B scavenger receptor, CD36 J Biol Chem 272 21654 21659
39. S Devaraj I Hugou I Jialal 2001 Alpha-tocopherol decreases CD36 expression in human monocyte-derived macrophages J Lipid Res 42 521 527
40. Y Tamura J Osuga H Adachi R Tozawa Y Takanezawa K Ohashi N Yahagi M Sekiya H Okazaki 2004 Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide J Biol Chem 279 30938 30944
41. H Steinhart R Rickert K Winkler 2003 Identification and analysis of conjugated linoleic acid isomers (CLA) Eur J Med Res 8 370 372
42. I Lorenzi A von Eckardstein C Cavelier S Radosavljevic L Rohrer 2008 Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI J Mol Med 86 171 183
43. DT Vistica P Skehan D Scudiero A Monks A Pittman MR Boyd 1991 Tetrazolium-based assays for cellular viability: a critical examination of selected parameters affecting formazan production Cancer Res 51 2515 2520
44. K Eder C Brandsch 2002 Effect of fatty acid composition of rapeseed oil on plasma lipids, fatty acid composition of tissues and susceptibility of low-density lipoprotein to lipid peroxidation in cholesterol-fed hamsters Eur J Lipid Sci Technol 104 3 13
45. JL Hojnacki RJ Nicolosi G Hoover N Liansa RG Ershow M El Lozy KG Haycs 1978 Comparison of two ultracentrifugation procedures for separation of nonhuman primate lipoproteins Anal Biochem 88 485 494
46. Fraenkel-Conrad H (1957) In: Colowick SP, Kaplan NO (eds) Methods in Enzymology, vol 4. Academic Press, New York, pp 247-269
47. R Ringseis A Muschick K Eder 2007 Dietary oxidized fat prevents ethanol-induced triacylglycerol accumulation and increases expression of PPARα target genes in rat liver J Nutr 137 77 83
48. M Westerterp M Van Eck W de Haan EH Offerman TJ Van Berkel LM Havekes PC Rensen 2007 Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages Atherosclerosis 195 e9 e16
49. EJ Noone HM Roche AP Nugent MJ Gibney 2002 The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects Br J Nutr 88 243 251
50. C Bocos M Göttlicher K Gearing C Banner E Enmark M Teboul A Crickmore JA Gustafsson 1995 Fatty acid activation of peroxisome proliferator-activated receptor (PPAR) J Steroid Biochem Mol Biol 53 467 473
51. M Ricote AC Li TM Willson CJ Kelly CK Glass 1998 The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 79 82
52. K Valeille J Ferezou M Parquet G Amsler D Gripois A Quignard-Boulange JC Martin 2006 The natural concentration of the conjugated linoleic acid, cis-9, trans-11, in milk fat has antiatherogenic effects in hyperlipidemic hamsters J Nutr 136 1305 1310
53. M Hirakata R Tozawa Y Imura Y Sugiyama 2004 Comparison of the effects of pioglitazone and rosiglitazone on macrophage foam cell formation Biochem Biophys Res Commun 323 782 788
54. S Schleser R Ringseis K Eder 2006 Conjugated linoleic acids have no effect on TNFα-induced adhesion molecule expression, U937 monocyte adhesion, and chemokine release in human aortic endothelial cells Atherosclerosis 186 337 344
55. M Febbraio EA Podrez JD Smith DP Hajjar SL Hazen HF Hoff K Sharma RL Silverstein 2000 Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerosis lesions development in mice J Clin Invest 105 1049 1056
56. E Stachowska V Dziedziejko K Safranow I Gutowska G Adler A Ciechanowicz B Machalinski D Chlubek 2007 Inhibition of phospholipase A2 activity by conjugated linoleic acids in human macrophages Eur J Nutr 46 28 33
57. E Stachowska M Baśkiewicz-Masiuk V Dziedziejko G Adler J Bober B Machaliński D Chlubek 2007 Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression Lipids 42 707 716