-
1
-
-
84948805443
-
Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1)
-
In Probe Reports from the NIH Molecular Libraries Program
-
Adibekian, A., Martin, B.R., Chang, J.W., Hsu, K.L., Tsuboi, K., Bachovchin, D.A., Speers, A.E., Brown, S.J., Spicer, T., et al. Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 1 (LYPLA1). 2010, In Probe Reports from the NIH Molecular Libraries Program.
-
(2010)
-
-
Adibekian, A.1
Martin, B.R.2
Chang, J.W.3
Hsu, K.L.4
Tsuboi, K.5
Bachovchin, D.A.6
Speers, A.E.7
Brown, S.J.8
Spicer, T.9
-
2
-
-
84948805443
-
Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2)
-
In Probe Reports from the NIH Molecular Libraries Program
-
Adibekian, A., Martin, B.R., Chang, J.W., Hsu, K.L., Tsuboi, K., Bachovchin, D.A., Speers, A.E., Brown, S.J., Spicer, T., Fernandez-Vega, V., et al. Characterization of a Selective, Reversible Inhibitor of Lysophospholipase 2 (LYPLA2). 2010, In Probe Reports from the NIH Molecular Libraries Program.
-
(2010)
-
-
Adibekian, A.1
Martin, B.R.2
Chang, J.W.3
Hsu, K.L.4
Tsuboi, K.5
Bachovchin, D.A.6
Speers, A.E.7
Brown, S.J.8
Spicer, T.9
Fernandez-Vega, V.10
-
3
-
-
84945474457
-
Optimization and Characterization of a Triazole Urea Dual Inhibitor for Lysophospholipase 1 (LYPLA1) and Lysophospholipase 2 (LYPLA2)
-
In Probe Reports from the NIH Molecular Libraries Program
-
Adibekian, A., Martin, B.R., Speers, A.E., Brown, S.J., Spicer, T., Fernandez-Vega, V., Ferguson, J., Cravatt, B.F., Hodder, P., Rosen, H., Optimization and Characterization of a Triazole Urea Dual Inhibitor for Lysophospholipase 1 (LYPLA1) and Lysophospholipase 2 (LYPLA2). 2010, In Probe Reports from the NIH Molecular Libraries Program.
-
(2010)
-
-
Adibekian, A.1
Martin, B.R.2
Speers, A.E.3
Brown, S.J.4
Spicer, T.5
Fernandez-Vega, V.6
Ferguson, J.7
Cravatt, B.F.8
Hodder, P.9
Rosen, H.10
-
4
-
-
79959376326
-
Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors
-
Adibekian, A., Martin, B.R., Wang, C., Hsu, K.L., Bachovchin, D.A., Niessen, S., Hoover, H., Cravatt, B.F., Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat. Chem. Biol. 7 (2011), 469–478.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 469-478
-
-
Adibekian, A.1
Martin, B.R.2
Wang, C.3
Hsu, K.L.4
Bachovchin, D.A.5
Niessen, S.6
Hoover, H.7
Cravatt, B.F.8
-
5
-
-
84863443024
-
Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes
-
Adibekian, A., Martin, B.R., Chang, J.W., Hsu, K.L., Tsuboi, K., Bachovchin, D.A., Speers, A.E., Brown, S.J., Spicer, T., Fernandez-Vega, V., et al. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes. J. Am. Chem. Soc. 134 (2012), 10345–10348.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 10345-10348
-
-
Adibekian, A.1
Martin, B.R.2
Chang, J.W.3
Hsu, K.L.4
Tsuboi, K.5
Bachovchin, D.A.6
Speers, A.E.7
Brown, S.J.8
Spicer, T.9
Fernandez-Vega, V.10
-
6
-
-
84864956480
-
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression
-
Anastas, J.N., Biechele, T.L., Robitaille, M., Muster, J., Allison, K.H., Angers, S., Moon, R.T., A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene 31 (2012), 3696–3708.
-
(2012)
Oncogene
, vol.31
, pp. 3696-3708
-
-
Anastas, J.N.1
Biechele, T.L.2
Robitaille, M.3
Muster, J.4
Allison, K.H.5
Angers, S.6
Moon, R.T.7
-
7
-
-
36349027945
-
The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells
-
Arpin-Andre, C., Mesnard, J.M., The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells. J. Biol. Chem. 282 (2007), 33132–33141.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 33132-33141
-
-
Arpin-Andre, C.1
Mesnard, J.M.2
-
8
-
-
78650495439
-
Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
-
Bachovchin, D.A., Ji, T., Li, W., Simon, G.M., Blankman, J.L., Adibekian, A., Hoover, H., Niessen, S., Cravatt, B.F., Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening. Proc. Natl. Acad. Sci. USA 107 (2010), 20941–20946.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 20941-20946
-
-
Bachovchin, D.A.1
Ji, T.2
Li, W.3
Simon, G.M.4
Blankman, J.L.5
Adibekian, A.6
Hoover, H.7
Niessen, S.8
Cravatt, B.F.9
-
9
-
-
0034628471
-
Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
-
Bilder, D., Perrimon, N., Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 403 (2000), 676–680.
-
(2000)
Nature
, vol.403
, pp. 676-680
-
-
Bilder, D.1
Perrimon, N.2
-
10
-
-
84940973446
-
SwissPalm: protein palmitoylation database
-
Blanc, M., David, F., Abrami, L., Migliozzi, D., Armand, F., Burgi, J., van der Goot, F.G., SwissPalm: protein palmitoylation database. F1000Res., 4, 2015, 261.
-
(2015)
F1000Res.
, vol.4
, pp. 261
-
-
Blanc, M.1
David, F.2
Abrami, L.3
Migliozzi, D.4
Armand, F.5
Burgi, J.6
van der Goot, F.G.7
-
11
-
-
84913594151
-
Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium
-
Boczonadi, V., Gillespie, R., Keenan, I., Ramsbottom, S.A., Donald-Wilson, C., Al Nazer, M., Humbert, P., Schwarz, R.J., Chaudhry, B., Henderson, D.J., Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium. Cardiovasc. Res. 104 (2014), 103–115.
-
(2014)
Cardiovasc. Res.
, vol.104
, pp. 103-115
-
-
Boczonadi, V.1
Gillespie, R.2
Keenan, I.3
Ramsbottom, S.A.4
Donald-Wilson, C.5
Al Nazer, M.6
Humbert, P.7
Schwarz, R.J.8
Chaudhry, B.9
Henderson, D.J.10
-
12
-
-
84922879684
-
Spectrin binding motifs regulate Scribble cortical dynamics and polarity function
-
Boeda, B., Etienne-Manneville, S., Spectrin binding motifs regulate Scribble cortical dynamics and polarity function. Elife, 4, 2015, 10.7554/eLife.04726.
-
(2015)
Elife
, vol.4
-
-
Boeda, B.1
Etienne-Manneville, S.2
-
13
-
-
84976907223
-
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
-
Chen, B., Zheng, B., DeRan, M., Jarugumilli, G.K., Fu, J., Brooks, Y.S., Wu, X., ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity. Nat. Chem. Biol. 12 (2016), 686–693.
-
(2016)
Nat. Chem. Biol.
, vol.12
, pp. 686-693
-
-
Chen, B.1
Zheng, B.2
DeRan, M.3
Jarugumilli, G.K.4
Fu, J.5
Brooks, Y.S.6
Wu, X.7
-
14
-
-
84937784363
-
Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases
-
Cognetta, A.B. 3rd, Niphakis, M.J., Lee, H.C., Martini, M.L., Hulce, J.J., Cravatt, B.F., Selective N-hydroxyhydantoin carbamate inhibitors of mammalian serine hydrolases. Chem. Biol. 22 (2015), 928–937.
-
(2015)
Chem. Biol.
, vol.22
, pp. 928-937
-
-
Cognetta, A.B.1
Niphakis, M.J.2
Lee, H.C.3
Martini, M.L.4
Hulce, J.J.5
Cravatt, B.F.6
-
15
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi, M., Zanconato, F., Azzolin, L., Forcato, M., Rosato, A., Frasson, C., Inui, M., Montagner, M., Parenti, A.R., Poletti, A., et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147 (2011), 759–772.
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
-
16
-
-
84895096129
-
Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation
-
Davda, D., Martin, B.R., Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm 5 (2014), 268–276.
-
(2014)
Medchemcomm
, vol.5
, pp. 268-276
-
-
Davda, D.1
Martin, B.R.2
-
17
-
-
0037603113
-
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
-
Debnath, J., Muthuswamy, S.K., Brugge, J.S., Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30 (2003), 256–268.
-
(2003)
Methods
, vol.30
, pp. 256-268
-
-
Debnath, J.1
Muthuswamy, S.K.2
Brugge, J.S.3
-
18
-
-
77952541156
-
Small-molecule inhibition of APT1 affects Ras localization and signaling
-
Dekker, F.J., Rocks, O., Vartak, N., Menninger, S., Hedberg, C., Balamurugan, R., Wetzel, S., Renner, S., Gerauer, M., Scholermann, B., et al. Small-molecule inhibition of APT1 affects Ras localization and signaling. Nat. Chem. Biol. 6 (2010), 449–456.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 449-456
-
-
Dekker, F.J.1
Rocks, O.2
Vartak, N.3
Menninger, S.4
Hedberg, C.5
Balamurugan, R.6
Wetzel, S.7
Renner, S.8
Gerauer, M.9
Scholermann, B.10
-
19
-
-
33846562882
-
Phosphatase and feedback regulation of Raf-1 signaling
-
Dhillon, A.S., von Kriegsheim, A., Grindlay, J., Kolch, W., Phosphatase and feedback regulation of Raf-1 signaling. Cell Cycle 6 (2007), 3–7.
-
(2007)
Cell Cycle
, vol.6
, pp. 3-7
-
-
Dhillon, A.S.1
von Kriegsheim, A.2
Grindlay, J.3
Kolch, W.4
-
20
-
-
80053174316
-
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling
-
Doggett, K., Grusche, F.A., Richardson, H.E., Brumby, A.M., Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling. BMC Dev. Biol., 11, 2011, 57.
-
(2011)
BMC Dev. Biol.
, vol.11
, pp. 57
-
-
Doggett, K.1
Grusche, F.A.2
Richardson, H.E.3
Brumby, A.M.4
-
21
-
-
1642458225
-
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble
-
Dow, L.E., Brumby, A.M., Muratore, R., Coombe, M.L., Sedelies, K.A., Trapani, J.A., Russell, S.M., Richardson, H.E., Humbert, P.O., hScrib is a functional homologue of the Drosophila tumour suppressor Scribble. Oncogene 22 (2003), 9225–9230.
-
(2003)
Oncogene
, vol.22
, pp. 9225-9230
-
-
Dow, L.E.1
Brumby, A.M.2
Muratore, R.3
Coombe, M.L.4
Sedelies, K.A.5
Trapani, J.A.6
Russell, S.M.7
Richardson, H.E.8
Humbert, P.O.9
-
22
-
-
84880769933
-
Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble
-
Elsum, I.A., Humbert, P.O., Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble. Cells Tissues Organs 198 (2013), 1–11.
-
(2013)
Cells Tissues Organs
, vol.198
, pp. 1-11
-
-
Elsum, I.A.1
Humbert, P.O.2
-
23
-
-
84902176984
-
Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with Basal breast cancer
-
Feigin, M.E., Akshinthala, S.D., Araki, K., Rosenberg, A.Z., Muthuswamy, L.B., Martin, B., Lehmann, B.D., Berman, H.K., Pietenpol, J.A., Cardiff, R.D., et al. Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with Basal breast cancer. Cancer Res. 74 (2014), 3180–3194.
-
(2014)
Cancer Res.
, vol.74
, pp. 3180-3194
-
-
Feigin, M.E.1
Akshinthala, S.D.2
Araki, K.3
Rosenberg, A.Z.4
Muthuswamy, L.B.5
Martin, B.6
Lehmann, B.D.7
Berman, H.K.8
Pietenpol, J.A.9
Cardiff, R.D.10
-
24
-
-
33747465415
-
Human discs large and Scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression
-
Gardiol, D., Zacchi, A., Petrera, F., Stanta, G., Banks, L., Human discs large and Scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression. Int. J. Cancer 119 (2006), 1285–1290.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1285-1290
-
-
Gardiol, D.1
Zacchi, A.2
Petrera, F.3
Stanta, G.4
Banks, L.5
-
25
-
-
0018099247
-
Malignant neoplasms of genetic origin in Drosophila melanogaster
-
Gateff, E., Malignant neoplasms of genetic origin in Drosophila melanogaster. Science 200 (1978), 1448–1459.
-
(1978)
Science
, vol.200
, pp. 1448-1459
-
-
Gateff, E.1
-
26
-
-
79952672026
-
Signaling from the living plasma membrane
-
Grecco, H.E., Schmick, M., Bastiaens, P.I., Signaling from the living plasma membrane. Cell 144 (2011), 897–909.
-
(2011)
Cell
, vol.144
, pp. 897-909
-
-
Grecco, H.E.1
Schmick, M.2
Bastiaens, P.I.3
-
27
-
-
35148819132
-
aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia
-
Grifoni, D., Garoia, F., Bellosta, P., Parisi, F., De Biase, D., Collina, G., Strand, D., Cavicchi, S., Pession, A., aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia. Oncogene 26 (2007), 5960–5965.
-
(2007)
Oncogene
, vol.26
, pp. 5960-5965
-
-
Grifoni, D.1
Garoia, F.2
Bellosta, P.3
Parisi, F.4
De Biase, D.5
Collina, G.6
Strand, D.7
Cavicchi, S.8
Pession, A.9
-
28
-
-
77950485564
-
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
-
Grzeschik, N.A., Parsons, L.M., Allott, M.L., Harvey, K.F., Richardson, H.E., Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr. Biol. 20 (2010), 573–581.
-
(2010)
Curr. Biol.
, vol.20
, pp. 573-581
-
-
Grzeschik, N.A.1
Parsons, L.M.2
Allott, M.L.3
Harvey, K.F.4
Richardson, H.E.5
-
29
-
-
84879404146
-
Family-wide investigation of PDZ domain-mediated protein-protein interactions implicates beta-catenin in maintaining the integrity of tight junctions
-
Gujral, T.S., Karp, E.S., Chan, M., Chang, B.H., MacBeath, G., Family-wide investigation of PDZ domain-mediated protein-protein interactions implicates beta-catenin in maintaining the integrity of tight junctions. Chem. Biol. 20 (2013), 816–827.
-
(2013)
Chem. Biol.
, vol.20
, pp. 816-827
-
-
Gujral, T.S.1
Karp, E.S.2
Chan, M.3
Chang, B.H.4
MacBeath, G.5
-
30
-
-
84875237901
-
Profiling and inhibiting reversible palmitoylation
-
Hernandez, J.L., Majmudar, J.D., Martin, B.R., Profiling and inhibiting reversible palmitoylation. Curr. Opin. Chem. Biol. 17 (2013), 20–26.
-
(2013)
Curr. Opin. Chem. Biol.
, vol.17
, pp. 20-26
-
-
Hernandez, J.L.1
Majmudar, J.D.2
Martin, B.R.3
-
31
-
-
84971282424
-
Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition
-
Hernandez, J.L., Davda, D., Majmudar, J.D., Won, S.J., Prakash, A., Choi, A.I., Martin, B.R., Correlated S-palmitoylation profiling of Snail-induced epithelial to mesenchymal transition. Mol. Biosyst. 12 (2016), 1799–1808.
-
(2016)
Mol. Biosyst.
, vol.12
, pp. 1799-1808
-
-
Hernandez, J.L.1
Davda, D.2
Majmudar, J.D.3
Won, S.J.4
Prakash, A.5
Choi, A.I.6
Martin, B.R.7
-
32
-
-
56749170093
-
Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module
-
Humbert, P.O., Grzeschik, N.A., Brumby, A.M., Galea, R., Elsum, I., Richardson, H.E., Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module. Oncogene 27 (2008), 6888–6907.
-
(2008)
Oncogene
, vol.27
, pp. 6888-6907
-
-
Humbert, P.O.1
Grzeschik, N.A.2
Brumby, A.M.3
Galea, R.4
Elsum, I.5
Richardson, H.E.6
-
33
-
-
84894371194
-
Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes
-
Ivarsson, Y., Arnold, R., McLaughlin, M., Nim, S., Joshi, R., Ray, D., Liu, B., Teyra, J., Pawson, T., Moffat, J., et al. Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes. Proc. Natl. Acad. Sci. USA 111 (2014), 2542–2547.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 2542-2547
-
-
Ivarsson, Y.1
Arnold, R.2
McLaughlin, M.3
Nim, S.4
Joshi, R.5
Ray, D.6
Liu, B.7
Teyra, J.8
Pawson, T.9
Moffat, J.10
-
34
-
-
84937150608
-
Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer
-
Kohnz, R.A., Mulvihill, M.M., Chang, J.W., Hsu, K.L., Sorrentino, A., Cravatt, B.F., Bandyopadhyay, S., Goga, A., Nomura, D.K., Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer. ACS Chem. Biol. 10 (2015), 1624–1630.
-
(2015)
ACS Chem. Biol.
, vol.10
, pp. 1624-1630
-
-
Kohnz, R.A.1
Mulvihill, M.M.2
Chang, J.W.3
Hsu, K.L.4
Sorrentino, A.5
Cravatt, B.F.6
Bandyopadhyay, S.7
Goga, A.8
Nomura, D.K.9
-
35
-
-
84855253929
-
DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells
-
Li, Y., Martin, B.R., Cravatt, B.F., Hofmann, S.L., DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells. J. Biol. Chem. 287 (2012), 523–530.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 523-530
-
-
Li, Y.1
Martin, B.R.2
Cravatt, B.F.3
Hofmann, S.L.4
-
36
-
-
84956877118
-
ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization
-
Lin, D.T., Conibear, E., ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization. Elife, 4, 2015, e11306.
-
(2015)
Elife
, vol.4
, pp. e11306
-
-
Lin, D.T.1
Conibear, E.2
-
37
-
-
77957970275
-
The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble
-
Liu, H., Golebiewski, L., Dow, E.C., Krug, R.M., Javier, R.T., Rice, A.P., The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. J. Virol. 84 (2010), 11164–11174.
-
(2010)
J. Virol.
, vol.84
, pp. 11164-11174
-
-
Liu, H.1
Golebiewski, L.2
Dow, E.C.3
Krug, R.M.4
Javier, R.T.5
Rice, A.P.6
-
38
-
-
84863116741
-
Fibroblast activation protein: a potential therapeutic target in cancer
-
Liu, R., Li, H., Liu, L., Yu, J., Ren, X., Fibroblast activation protein: a potential therapeutic target in cancer. Cancer Biol. Ther. 13 (2012), 123–129.
-
(2012)
Cancer Biol. Ther.
, vol.13
, pp. 123-129
-
-
Liu, R.1
Li, H.2
Liu, L.3
Yu, J.4
Ren, X.5
-
39
-
-
84856468404
-
Global profiling of dynamic protein palmitoylation
-
Martin, B.R., Wang, C., Adibekian, A., Tully, S.E., Cravatt, B.F., Global profiling of dynamic protein palmitoylation. Nat. Methods 9 (2012), 84–89.
-
(2012)
Nat. Methods
, vol.9
, pp. 84-89
-
-
Martin, B.R.1
Wang, C.2
Adibekian, A.3
Tully, S.E.4
Cravatt, B.F.5
-
40
-
-
84655169623
-
Epithelial cell polarity, stem cells and cancer
-
Martin-Belmonte, F., Perez-Moreno, M., Epithelial cell polarity, stem cells and cancer. Nat. Rev. Cancer 12 (2012), 23–38.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 23-38
-
-
Martin-Belmonte, F.1
Perez-Moreno, M.2
-
41
-
-
85007427982
-
Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity
-
Mezencev, R., Matyunina, L.V., Jabbari, N., McDonald, J.F., Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity. BMC Cancer 16 (2016), 1–21.
-
(2016)
BMC Cancer
, vol.16
, pp. 1-21
-
-
Mezencev, R.1
Matyunina, L.V.2
Jabbari, N.3
McDonald, J.F.4
-
42
-
-
77957154303
-
The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction
-
Nagasaka, K., Pim, D., Massimi, P., Thomas, M., Tomaic, V., Subbaiah, V.K., Kranjec, C., Nakagawa, S., Yano, T., Taketani, Y., et al. The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction. Oncogene 29 (2010), 5311–5321.
-
(2010)
Oncogene
, vol.29
, pp. 5311-5321
-
-
Nagasaka, K.1
Pim, D.2
Massimi, P.3
Thomas, M.4
Tomaic, V.5
Subbaiah, V.K.6
Kranjec, C.7
Nakagawa, S.8
Yano, T.9
Taketani, Y.10
-
43
-
-
0033776810
-
Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase
-
Nakagawa, S., Huibregtse, J.M., Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase. Mol. Cell. Biol. 20 (2000), 8244–8253.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8244-8253
-
-
Nakagawa, S.1
Huibregtse, J.M.2
-
44
-
-
0842329915
-
Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix
-
Nakagawa, S., Yano, T., Nakagawa, K., Takizawa, S., Suzuki, Y., Yasugi, T., Huibregtse, J.M., Taketani, Y., Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix. Br. J. Cancer 90 (2004), 194–199.
-
(2004)
Br. J. Cancer
, vol.90
, pp. 194-199
-
-
Nakagawa, S.1
Yano, T.2
Nakagawa, K.3
Takizawa, S.4
Suzuki, Y.5
Yasugi, T.6
Huibregtse, J.M.7
Taketani, Y.8
-
45
-
-
73149109062
-
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
-
Nomura, D.K., Long, J.Z., Niessen, S., Hoover, H.S., Ng, S.W., Cravatt, B.F., Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell 140 (2010), 49–61.
-
(2010)
Cell
, vol.140
, pp. 49-61
-
-
Nomura, D.K.1
Long, J.Z.2
Niessen, S.3
Hoover, H.S.4
Ng, S.W.5
Cravatt, B.F.6
-
46
-
-
0242666126
-
A genetic screen in Drosophila for metastatic behavior
-
Pagliarini, R.A., Xu, T., A genetic screen in Drosophila for metastatic behavior. Science 302 (2003), 1227–1231.
-
(2003)
Science
, vol.302
, pp. 1227-1231
-
-
Pagliarini, R.A.1
Xu, T.2
-
47
-
-
80555157484
-
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia
-
Pearson, H.B., Perez-Mancera, P.A., Dow, L.E., Ryan, A., Tennstedt, P., Bogani, D., Elsum, I., Greenfield, A., Tuveson, D.A., Simon, R., et al. SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. J. Clin. Invest. 121 (2011), 4257–4267.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4257-4267
-
-
Pearson, H.B.1
Perez-Mancera, P.A.2
Dow, L.E.3
Ryan, A.4
Tennstedt, P.5
Bogani, D.6
Elsum, I.7
Greenfield, A.8
Tuveson, D.A.9
Simon, R.10
-
48
-
-
66149089196
-
PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma
-
Puustinen, P., Junttila, M.R., Vanhatupa, S., Sablina, A.A., Hector, M.E., Teittinen, K., Raheem, O., Ketola, K., Lin, S., Kast, J., et al. PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma. Cancer Res. 69 (2009), 2870–2877.
-
(2009)
Cancer Res.
, vol.69
, pp. 2870-2877
-
-
Puustinen, P.1
Junttila, M.R.2
Vanhatupa, S.3
Sablina, A.A.4
Hector, M.E.5
Teittinen, K.6
Raheem, O.7
Ketola, K.8
Lin, S.9
Kast, J.10
-
49
-
-
29144469472
-
The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin
-
Qin, Y., Capaldo, C., Gumbiner, B.M., Macara, I.G., The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J. Cell Biol. 171 (2005), 1061–1071.
-
(2005)
J. Cell Biol.
, vol.171
, pp. 1061-1071
-
-
Qin, Y.1
Capaldo, C.2
Gumbiner, B.M.3
Macara, I.G.4
-
50
-
-
1642377561
-
ONCOMINE: a cancer microarray database and integrated data-mining platform
-
Rhodes, D.R., Yu, J., Shanker, K., Deshpande, N., Varambally, R., Ghosh, D., Barrette, T., Pandey, A., Chinnaiyan, A.M., ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 6 (2004), 1–6.
-
(2004)
Neoplasia
, vol.6
, pp. 1-6
-
-
Rhodes, D.R.1
Yu, J.2
Shanker, K.3
Deshpande, N.4
Varambally, R.5
Ghosh, D.6
Barrette, T.7
Pandey, A.8
Chinnaiyan, A.M.9
-
51
-
-
77951913833
-
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins
-
Rocks, O., Gerauer, M., Vartak, N., Koch, S., Huang, Z.P., Pechlivanis, M., Kuhlmann, J., Brunsveld, L., Chandra, A., Ellinger, B., et al. The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell 141 (2010), 458–471.
-
(2010)
Cell
, vol.141
, pp. 458-471
-
-
Rocks, O.1
Gerauer, M.2
Vartak, N.3
Koch, S.4
Huang, Z.P.5
Pechlivanis, M.6
Kuhlmann, J.7
Brunsveld, L.8
Chandra, A.9
Ellinger, B.10
-
52
-
-
76649109937
-
RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia
-
Shields, D.J., Niessen, S., Murphy, E.A., Mielgo, A., Desgrosellier, J.S., Lau, S.K., Barnes, L.A., Lesperance, J., Bouvet, M., Tarin, D., et al. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proc. Natl. Acad. Sci. USA 107 (2010), 2189–2194.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2189-2194
-
-
Shields, D.J.1
Niessen, S.2
Murphy, E.A.3
Mielgo, A.4
Desgrosellier, J.S.5
Lau, S.K.6
Barnes, L.A.7
Lesperance, J.8
Bouvet, M.9
Tarin, D.10
-
53
-
-
33645132429
-
Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli
-
Takizawa, S., Nagasaka, K., Nakagawa, S., Yano, T., Nakagawa, K., Yasugi, T., Takeuchi, T., Kanda, T., Huibregtse, J.M., Akiyama, T., et al. Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli. Genes Cells 11 (2006), 453–464.
-
(2006)
Genes Cells
, vol.11
, pp. 453-464
-
-
Takizawa, S.1
Nagasaka, K.2
Nakagawa, S.3
Yano, T.4
Nakagawa, K.5
Yasugi, T.6
Takeuchi, T.7
Kanda, T.8
Huibregtse, J.M.9
Akiyama, T.10
-
54
-
-
84872539180
-
Fat chance! Getting a grip on a slippery modification
-
Tom, C.T., Martin, B.R., Fat chance! Getting a grip on a slippery modification. ACS Chem. Biol. 8 (2013), 46–57.
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 46-57
-
-
Tom, C.T.1
Martin, B.R.2
-
55
-
-
79959378518
-
Aberrant overexpression of the cell polarity module scribble in human cancer
-
Vaira, V., Faversani, A., Dohi, T., Maggioni, M., Nosotti, M., Tosi, D., Altieri, D.C., Bosari, S., Aberrant overexpression of the cell polarity module scribble in human cancer. Am. J. Pathol. 178 (2011), 2478–2483.
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 2478-2483
-
-
Vaira, V.1
Faversani, A.2
Dohi, T.3
Maggioni, M.4
Nosotti, M.5
Tosi, D.6
Altieri, D.C.7
Bosari, S.8
-
56
-
-
84981294741
-
Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells
-
Vujic, I., Sanlorenzo, M., Esteve-Puig, R., Vujic, M., Kwong, A., Tsumura, A., Murphy, R., Moy, A., Posch, C., Monshi, B., et al. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells. Oncotarget 7 (2016), 7297–7306.
-
(2016)
Oncotarget
, vol.7
, pp. 7297-7306
-
-
Vujic, I.1
Sanlorenzo, M.2
Esteve-Puig, R.3
Vujic, M.4
Kwong, A.5
Tsumura, A.6
Murphy, R.7
Moy, A.8
Posch, C.9
Monshi, B.10
-
57
-
-
84891806422
-
Defining the protein–protein interaction network of the human Hippo pathway
-
Wang, W., Li, X., Huang, J., Feng, L., Dolinta, K.G., Chen, J., Defining the protein–protein interaction network of the human Hippo pathway. Mol. Cell Proteomics 13 (2014), 119–131.
-
(2014)
Mol. Cell Proteomics
, vol.13
, pp. 119-131
-
-
Wang, W.1
Li, X.2
Huang, J.3
Feng, L.4
Dolinta, K.G.5
Chen, J.6
-
58
-
-
85006757943
-
Molecular mechanism for isoform-selective inhibition of acyl protein thioesterases 1 and 2 (APT1 and APT2)
-
Won, S.J., Davda, D., Labby, K.J., Hwang, S.Y., Pricer, R., Majmudar, J.D., Armacost, K.A., Rodriguez, L.A., Rodriguez, C.L., Chong, F.S., et al. Molecular mechanism for isoform-selective inhibition of acyl protein thioesterases 1 and 2 (APT1 and APT2). ACS Chem. Biol. 11 (2016), 3374–3382.
-
(2016)
ACS Chem. Biol.
, vol.11
, pp. 3374-3382
-
-
Won, S.J.1
Davda, D.2
Labby, K.J.3
Hwang, S.Y.4
Pricer, R.5
Majmudar, J.D.6
Armacost, K.A.7
Rodriguez, L.A.8
Rodriguez, C.L.9
Chong, F.S.10
-
59
-
-
85013844236
-
Affinity-based selectivity profiling of an in-class selective competitive inhibitor of acyl protein thioesterase 2
-
Won, S.J., Eschweiler, J.D., Majmudar, J.D., Chong, F.S., Hwang, S.Y., Ruotolo, B.T., Martin, B.R., Affinity-based selectivity profiling of an in-class selective competitive inhibitor of acyl protein thioesterase 2. ACS Med. Chem. Lett., 2016, 10.1021/acsmedchemlett.6b00441.
-
(2016)
ACS Med. Chem. Lett.
-
-
Won, S.J.1
Eschweiler, J.D.2
Majmudar, J.D.3
Chong, F.S.4
Hwang, S.Y.5
Ruotolo, B.T.6
Martin, B.R.7
-
60
-
-
75749106942
-
Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion
-
Wu, M., Pastor-Pareja, J.C., Xu, T., Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature 463 (2010), 545–548.
-
(2010)
Nature
, vol.463
, pp. 545-548
-
-
Wu, M.1
Pastor-Pareja, J.C.2
Xu, T.3
-
61
-
-
52049122800
-
Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth
-
Yamanaka, T., Ohno, S., Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth. Front Biosci. 13 (2008), 6693–6707.
-
(2008)
Front Biosci.
, vol.13
, pp. 6693-6707
-
-
Yamanaka, T.1
Ohno, S.2
-
62
-
-
84890205665
-
An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth
-
Young, L.C., Hartig, N., Munoz-Alegre, M., Oses-Prieto, J.A., Durdu, S., Bender, S., Vijayakumar, V., Vietri Rudan, M., Gewinner, C., Henderson, S., et al. An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth. Mol. Cell 52 (2013), 679–692.
-
(2013)
Mol. Cell
, vol.52
, pp. 679-692
-
-
Young, L.C.1
Hartig, N.2
Munoz-Alegre, M.3
Oses-Prieto, J.A.4
Durdu, S.5
Bender, S.6
Vijayakumar, V.7
Vietri Rudan, M.8
Gewinner, C.9
Henderson, S.10
-
63
-
-
56349098933
-
Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
-
Zhan, L., Rosenberg, A., Bergami, K.C., Yu, M., Xuan, Z., Jaffe, A.B., Allred, C., Muthuswamy, S.K., Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 135 (2008), 865–878.
-
(2008)
Cell
, vol.135
, pp. 865-878
-
-
Zhan, L.1
Rosenberg, A.2
Bergami, K.C.3
Yu, M.4
Xuan, Z.5
Jaffe, A.B.6
Allred, C.7
Muthuswamy, S.K.8
-
64
-
-
84871479018
-
Boron-based inhibitors of acyl protein thioesterases 1 and 2
-
Zimmermann, T.J., Bürger, M., Tashiro, E., Kondoh, Y., Martinez, N.E., Görmer, K., Rosin-Steiner, S., Shimizu, T., Ozaki, S., Mikoshiba, K., et al. Boron-based inhibitors of acyl protein thioesterases 1 and 2. ChemBioChem 14 (2013), 115–122.
-
(2013)
ChemBioChem
, vol.14
, pp. 115-122
-
-
Zimmermann, T.J.1
Bürger, M.2
Tashiro, E.3
Kondoh, Y.4
Martinez, N.E.5
Görmer, K.6
Rosin-Steiner, S.7
Shimizu, T.8
Ozaki, S.9
Mikoshiba, K.10
|