Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer

ACS Chemical Biology

Volumn 10, Issue 7, 2015, Pages 1624-1630

  Kohnz, Rebecca A ^a   Mulvihill, Melinda M ^a   Chang, Jae Won ^b   Hsu, Ku Lung ^c   Sorrentino, Antonio ^d   Cravatt, Benjamin F ^b   Bandyopadhyay, Sourav ^d   Goga, Andrei ^d,e   Nomura, Daniel K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ACYLGLYCEROL LIPASE; FATTY ACID SYNTHASE; HYDROLASE; PLATELET ACTIVATING FACTOR ACETYLHYDROLASE 1B2; PLATELET ACTIVATING FACTOR ACETYLHYDROLASE 1B3; SERINE; UNCLASSIFIED DRUG; MICROTUBULE ASSOCIATED PROTEIN; PAFAH1B2 PROTEIN, HUMAN; PAFAH1B3 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; LIPID METABOLISM; MELANOMA; ONCOGENE; OVARY CANCER; PATHOGENICITY; PRIORITY JOURNAL; PROSTATE CANCER; REGULATORY MECHANISM; UPREGULATION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; METABOLOME; NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; CELL LINE, TUMOR; HUMANS; LIPID METABOLISM; METABOLOME; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASMS;

EID: 84937150608     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00053     Document Type: Article

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