TLR3 downregulates expression of schizophrenia gene Disc1 via MYD88 to control neuronal morphology

EMBO Reports

Volumn 18, Issue 1, 2017, Pages 169-183

  Chen, Chiung Ya ^a   Liu, Hsin Yu ^a   Hsueh, Yi Ping ^a  

^a INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

Author keywords

dendritic growth; dendritic spine formation; innate immunity; neonatal infection; neural development

Indexed keywords

CYTOKINE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; POLYINOSINIC ACID; PROTEIN; TOLL LIKE RECEPTOR 3; BIOLOGICAL MARKER; DISC1 PROTEIN, HUMAN; NERVE PROTEIN;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AXON; CELL ACTIVATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DENDRITIC SPINE; ELECTROPORATION; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GENETIC TRANSFECTION; GROWTH REGULATION; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MENTAL HEALTH; MIXED CELL CULTURE; MORPHOGENESIS; MOUSE; MYELOID DENDRITIC CELL; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL CULTURE; CELL LINE; DENDRITE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

ANIMALS; BIOMARKERS; CELL LINE; CELLS, CULTURED; CYTOKINES; DENDRITES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, KNOCKOUT; MORPHOGENESIS; MYELOID DIFFERENTIATION FACTOR 88; NERVE TISSUE PROTEINS; NEURONS; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3;

EID: 85008190897     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201642586     Document Type: Article

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