The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3

Structure

Volumn 25, Issue 1, 2017, Pages 121-131

  McPhail, Jacob A ^a   Ottosen, Erik H ^a   Jenkins, Meredith L ^a   Burke, John E ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

Author keywords

ACBD3; HDX MS; hydrogen deuterium exchange mass spectrometry; lipid signaling; phosphatidylinositol 4 kinase; phosphoinositide; PI4K; PI4KB; picornaviruses; X ray crystallography

Indexed keywords

ACBD3 PROTEIN; ACYL COENZYME A BINDING DOMAIN CONTAINING PROTEIN 3; AICHI VIRUS 3A PROTEIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 4 KINASE BETA; PHOSPHATIDYLINOSITOL 4 KINASE III BETA; PHOSPHATIDYLINOSITOL KINASE; PROTEIN; UNCLASSIFIED DRUG; VIRAL PROTEIN; ACBD3 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 4-KINASE IIIBETA, HUMAN; PHOSPHOTRANSFERASE; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AICHI VIRUS; AICHI VIRUS 3A; ARTICLE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DEUTERIUM HYDROGEN EXCHANGE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; SENSITIZATION; CELL MEMBRANE; CHEMISTRY; ENZYME ACTIVATION; HUMAN; KOBUVIRUS; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; VIRUS REPLICATION; X RAY CRYSTALLOGRAPHY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BINDING SITES; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; ENZYME ACTIVATION; HUMANS; KOBUVIRUS; MASS SPECTROMETRY; MEMBRANE PROTEINS; MODELS, MOLECULAR; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN CONFORMATION; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 85007578840     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2016.11.016     Document Type: Article

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