GBF1- and ACBD3-independent recruitment of PI4KIIIß to replication sites by rhinovirus 3A proteins

Journal of Virology

Volumn 89, Issue 3, 2015, Pages 1913-1918

  Dorobantu, Cristina M ^a,b   Ford Siltz, Lauren A ^c   Sittig, Simone P ^a   Lanke, Kjerstin H W ^a   Belov, George A ^c   van Kuppeveld, Frank J M ^a,b   van der Schaar, Hilde M ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDYLINOSITOL KINASE; PROTEIN 3A; PROTEIN ACBD3; PROTEIN GBF1; PROTEIN PI4KIIIBETA; UNCLASSIFIED DRUG; VIRUS PROTEIN; ACBD3 PROTEIN, HUMAN; CORE PROTEIN; GBF1 PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 4-KINASE IIIBETA, HUMAN; PHOSPHOTRANSFERASE; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN RHINOVIRUS; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; VIRUS REPLICATION; HOST PATHOGEN INTERACTION; METABOLISM; PHYSIOLOGY; RHINOVIRUS;

COXSACKIEVIRUS; ENTEROVIRUS; HUMAN RHINOVIRUS 3; POLIOVIRUS; RHINOVIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HOST-PATHOGEN INTERACTIONS; HUMANS; MEMBRANE PROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; RHINOVIRUS; VIRAL CORE PROTEINS;

EID: 84921481887     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02830-14     Document Type: Article

References (18)

1. Hsu N-Y, Ilnytska O, Belov G, Santiana M, Chen Y-H, Takvorian PM, Pau C, van der Schaar H, Kaushik-Basu N, Balla T, Cameron CE, Ehrenfeld E, van Kuppeveld FJM, Altan-Bonnet N. 2010. Viral reorganization of the secretory pathway generates distinct organelles forRNAreplication. Cell 141:799-811. http://dx.doi.org/10.1016/j.cell.2010.03.050.
2. van der Schaar HM, Leyssen P, Thibaut HJ, de Palma A, van der Linden L, Lanke KHW, Lacroix C, Verbeken E, Conrath K, Macleod AM, Mitchell DR, Palmer NJ, van de Poël H, Andrews M, Neyts J, van Kuppeveld FJM. 2013. A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor PI4KIIIß. Antimicrob Agents Chemother 57:4971-4981. http://dx.doi.org/10.1128/AAC.01175-13.
3. Godi A, Di Campli A, Konstantakopoulos A, Di Tullio G, Alessi DR, Kular GS, Daniele T, Marra P, Lucocq JM, De Matteis MA. 2004. FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nat Cell Biol 6:393-404. http://dx.doi.org/10.1038/ncb1119.
4. Donaldson JG, Jackson CL. 2000. Regulators and effectors of the ARF GTPases. Curr Opin Cell Biol 12:475-482. http://dx.doi.org/10.1016/S0955-0674(00)00119-8.
5. Sasaki J, Ishikawa K, Arita M, Taniguchi K. 2012. ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites. EMBO J 31:754-766. http://dx.doi.org/10.1038/emboj.2011.429.
6. Sohda M, Misumi Y, Yamamoto A, Yano A, Nakamura N, Ikehara Y. 2001. Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin. J Biol Chem 276:45298-45306. http://dx.doi.org/10.1074/jbc.M108961200.
7. Wessels E, Duijsings D, Niu T-K, Neumann S, Oorschot VM, de Lange F, Lanke KHW, Klumperman J, Henke A, Jackson CL, Melchers WJG, van Kuppeveld FJM. 2006. A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1. Dev Cell 11:191-201. http://dx.doi.org/10.1016/j.devcel.2006.06.005.
8. Wessels E, Duijsings D, Lanke KHW, van Dooren SHJ, Jackson CL, Melchers WJG, van Kuppeveld FJM. 2006. Effects of picornavirus 3A proteins on protein transport and GBF1-dependent COP-I recruitment. J Virol 80:11852-11860. http://dx.doi.org/10.1128/JVI.01225-06.
9. Dorobantu CM, van der Schaar HM, Ford LA, Strating JRPM, Ulferts R, Fang Y, Belov G, van Kuppeveld FJM. 2014. Recruitment of PI4KIIIß to coxsackievirusB3replication organelles is independent of ACBD3, GBF1, and Arf1. J Virol 88:2725-2736. http://dx.doi.org/10.1128/JVI.03650-13.
10. Téoulé F, Brisac C, Pelletier I, Vidalain P-O, Jégouic S, Mirabelli C, Bessaud M, Combelas N, Autret A, Tangy F, Delpeyroux F, Blondel B. 2013. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-11046. http://dx.doi.org/10.1128/JVI.00304-13.
11. Belov GA, Feng Q, Nikovics K, Jackson CL, Ehrenfeld E. 2008. A critical role of a cellular membrane traffic protein in poliovirus RNA replication. PLoS Pathog 4:e1000216. http://dx.doi.org/10.1371/journal.ppat.1000216.
12. Belov GA, Altan-Bonnet N, Kovtunovych G, Jackson CL, Lippincott-Schwartz J, Ehrenfeld E. 2007. Hijacking components of the cellular secretory pathway for replication of poliovirus RNA. J Virol 81:558-567. http://dx.doi.org/10.1128/JVI.01820-06.
13. Irurzun A, Perez L, Carrasco L. 1992. Involvement of membrane traffic in the replication of poliovirus genomes: effects of brefeldin A. Virology 191:166-175. http://dx.doi.org/10.1016/0042-6822(92)90178-R.
14. van der Linden L, van der Schaar HM, Lanke KHW, Neyts J, van Kuppeveld FJM. 2010. Differential effects of the putative GBF1 inhibitors GolgicideAand AG1478 on enterovirus replication. J Virol 84:7535-7542. http://dx.doi.org/10.1128/JVI.02684-09.
15. Lanke KHW, van der Schaar HM, Belov GA, Feng Q, Duijsings D, Jackson CL, Ehrenfeld E, van Kuppeveld FJM. 2009. GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replication. J Virol 83:11940-11949. http://dx.doi.org/10.1128/JVI.01244-09.
16. Spickler C, Lippens J, Laberge M-K, Desmeules S, Bellavance E, Garneau M, Guo T, Hucke O, Leyssen P, Neyts J, Vaillancourt FH, Décor A, O'Meara J, Franti M, Gauthier A. 2013. Phosphatidylinositol 4-kinase III beta is essential for the replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo. Antimicrob Agents Chemother 57:3358-3368. http://dx.doi.org/10.1128/AAC.00303-13.
17. Greninger AL, Knudsen GM, Betegon M, Burlingame AL, Derisi JL. 2012. The 3A protein from multiple picornaviruses utilizes the Golgi adaptor protein ACBD3 to recruit PI4KIIIß. J Virol 86:3605-3616. http://dx.doi.org/10.1128/JVI.06778-11.
18. Arita M. 2014. Phosphatidylinositol-4 kinase III beta and oxysterolbinding protein accumulate unesterified cholesterol on poliovirusinduced membrane structure. Microbiol Immunol 58:239-256. http://dx.doi.org/10.1111/1348-0421.12144.