Mutations in encephalomyocarditis virus 3A protein uncouple the dependency of genome replication on host factors phosphatidylinositol 4-kinase IIIα and oxysterol-binding protein

mSphere

Volumn 1, Issue 3, 2016, Pages

  Dorobantu, Cristina M ^a   Albulescu, Lucian ^a   Lyoo, Heyrhyoung ^a   van Kampen, Mirjam ^a   De Francesco, Raffaele ^b   Lohmann, Volker ^c   Harak, Christian ^c   van der Schaar, Hilde M ^a   Strating, Jeroen R P M ^a   Gorbaleny, Alexander E ^a,d,e   van Kuppeveld, Frank J M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b Istituto Nazionale di Genetica Molecolare   (Italy)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Cholesterol; EMCV; Mutants; OSBP; PI4KA; PI4P; Picornavirus; Replication organelles; Viral resistance

Indexed keywords

EID: 84992330143     PISSN: None     EISSN: 23795042     Source Type: Journal    
DOI: 10.1128/mSphere.00068-16     Document Type: Article

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