Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis

Biomaterials

Volumn 120, Issue , 2017, Pages 94-102

  Lee, Jaewoo ^a   Jackman, Jennifer G ^b   Kwun, Jean ^a   Manook, Miriam ^a   Moreno, Angelo ^a   Elster, Eric A ^c   Kirk, Allan D ^a   Leong, Kam W ^b,d   Sullenger, Bruce A ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Duke University   (United States)

^c WALTER REED ARMY MEDICAL CENTER   (United States)

^d Department of Earth and Environmental Sciences   (United States)

Author keywords

Inflammation; Microfiber mesh; Nucleic acid scavenger; Thrombosis; Toll like receptor

Indexed keywords

BIOMOLECULES; BLOOD VESSELS; DISEASES; MESH GENERATION; PATHOLOGY; PATIENT TREATMENT; SCAVENGING; TISSUE;

HIGH-MOBILITY GROUPS; INFLAMMATION; INNATE IMMUNE RESPONSE; MICRO-FIBER; POLYAMIDOAMINE DENDRIMERS; THERAPEUTIC AGENTS; THROMBOSIS; TOLL-LIKE RECEPTORS;

NUCLEIC ACIDS;

DENDRIMER; HIGH MOBILITY GROUP B1 PROTEIN; IMMOBILIZED NUCLEIC ACID; MICROFIBER MESH; NANOMESH; NUCLEIC ACID; POLYAMIDOAMINE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG; ALARMIN; NANOFIBER;

ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING; DAMAGE ASSOCIATED MOLECULAR PATTERN; ELECTRON MICROSCOPY; ELECTROSPINNING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INJURY; INNATE IMMUNITY; LUNG FIBROBLAST; MOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOELASTOGRAPHY; THROMBOSIS; ABSORPTION; ANIMAL; CELL CULTURE; CHEMISTRY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MATERIALS TESTING; PROCEDURES; TREATMENT OUTCOME; ULTRAFILTRATION;

ABSORPTION, PHYSICOCHEMICAL; ALARMINS; ANIMALS; CELLS, CULTURED; DENDRIMERS; HUMANS; INFLAMMATION; MATERIALS TESTING; MICE; NANOFIBERS; NUCLEIC ACIDS; THROMBOSIS; TREATMENT OUTCOME; ULTRAFILTRATION;

EID: 85007507466     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.12.024     Document Type: Article

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