Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

Nature Communications

Volumn 5, Issue , 2014, Pages

  Takemura, Naoki ^a   Kawasaki, Takumi ^b,c,d   Kunisawa, Jun ^a,e   Sato, Shintaro ^a,f   Lamichhane, Aayam ^a   Kobiyama, Kouji ^b,e   Aoshi, Taiki ^b,e   Ito, Junichi ^e   Mizuguchi, Kenji ^e   Karuppuchamy, Thangaraj ^b,c   Matsunaga, Kouta ^a   Miyatake, Shoichiro ^g   Mori, Nobuko ^h   Tsujimura, Tohru ⁱ   Satoh, Takashi ^b,c   Kumagai, Yutaro ^b,c   Kawai, Taro ^d   Standley, Daron M ^b   Ishii, Ken J ^b,e   Kiyono, Hiroshi ^a,f   Akira, Shizuo ^b,c   Uematsu, Satoshi ^a   more..

^a THE UNIVERSITY OF TOKYO   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^e NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^g TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^h Osaka Prefecture University   (Japan)

ⁱ HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; RNA; TOLL LIKE RECEPTOR 3;

CELL ORGANELLE; GASTROENTERITIS; GENOME; GIS; INHIBITOR; RADIATION BALANCE; RODENT; STABILIZATION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CRYPT CELL; DNA DAMAGE; FEMALE; GAMMA IRRADIATION; GASTROINTESTINAL DISEASE; MOUSE; NONHUMAN; PATHOGENESIS; RADIATION EXPOSURE; RADIATION INDUCED GASTROINTESTINAL SYNDROME; RADIATION INJURY; RECEPTOR BLOCKING; RNA BINDING;

ANIMALS; APOPTOSIS; FEMALE; GASTROINTESTINAL DISEASES; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; RADIATION INJURIES; RADIATION, IONIZING; TOLL-LIKE RECEPTOR 3; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84897895944     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4492     Document Type: Article

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